J. Epp

发表

The discovery of Arylex™ active and Rinskor™ active: Two novel auxin herbicides.

Carla N. Yerkes, Christian T. Lowe, J. Ruiz, 2016, Bioorganic & medicinal chemistry.

Inhibitors of human neutrophil cathepsin G: structural and biochemical studies.

W. Groutas, J. Epp, M. Brubaker, 1992, Archives of biochemistry and biophysics.

Mechanism-based inhibition of human leukocyte elastase and cathepsin G by substituted dihydrouracils.

H. Huang, W. Groutas, J. Epp, 1994, Biochimica et biophysica acta.

Facile Preparation of Nucleoside-5'-carboxylic Acids.

T. Widlanski, J. Epp, 1999, The Journal of organic chemistry.

Potential mechanism-based inhibitors of proteolytic enzymes

W. Groutas, J. Epp, M. Brubaker, 1992 .

Design, synthesis, and in vitro inhibitory activity toward human leukocyte elastase, cathepsin G, and proteinase 3 of saccharin-derived sulfones and congeners.

O. Prakash, W. Groutas, R. Kuang, 1996, Bioorganic & medicinal chemistry.

Isoxazoline derivatives as potential inhibitors of the proteolytic enzymes human leukocyte elastase, cathepsin G and proteinase 3: a structure-activity relationship study.

W. Groutas, E. H. Kim, J. Epp, 1995, Bioorganic & medicinal chemistry.

3-(Alkylthio)-N-hydroxysuccinimide derivatives: potent inhibitors of human leukocyte elastase.

W. Groutas, J. Epp, M. Brubaker, 1993, Biochimica et biophysica acta.

Utilization of the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold in the design of potent inhibitors of serine proteases: SAR studies using carboxylates.

W. Groutas, S. Ruan, R. Kuang, 2000, Bioorganic & medicinal chemistry.

Potent and specific inhibition of human leukocyte elastase, cathepsin G and proteinase 3 by sulfone derivatives employing the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold.

W. Groutas, S. Ruan, R. Kuang, 1998, Bioorganic & medicinal chemistry.

The Gabriel-Colman rearrangement in biological systems: design, synthesis and biological evaluation of phthalimide and saccharin derivatives as potential mechanism-based inhibitors of human leukocyte elastase, cathepsin G and proteinase 3.

J. Hoidal, W. Groutas, R. Kuang, 1995, Bioorganic & medicinal chemistry.

A general approach toward the design of inhibitors of serine proteinases: inhibition of human leukocyte elastase by substituted dihydrouracils

W. Groutas, J. Epp, M. Brubaker, 1992 .

A General Inhibitor Scaffold for Serine Proteases with a (Chymo)trypsin-Like Fold: Solution-Phase Construction and Evaluation of the First Series of Libraries of Mechanism-Based Inhibitors

N. Schechter, W. Groutas, S. Ruan, 1999 .

Structure-based design of a general class of mechanism-based inhibitors of the serine proteinases employing a novel amino acid-derived heterocyclic scaffold.

O. Prakash, W. Groutas, S. Ruan, 1997, Biochemistry.

Mechanism-based inactivation of human leukocyte elastase via an enzyme-induced sulfonamide fragmentation process.

M. V. van Stipdonk, W. Groutas, K. Alliston, 2004, Archives of biochemistry and biophysics.

Inhibition of human leukocyte elastase and cathepsin G by isoxazoline derivatives

W. Groutas, J. Epp, M. Brubaker, 1992 .

Efficient inhibition of human leukocyte elastase and cathepsin G by saccharin derivatives.

H. Huang, W. Groutas, J. Epp, 1993, Journal of medicinal chemistry.

Discovery and SAR of Halauxifen Methyl: A Novel Auxin Herbicide

Carla N. Yerkes, J. Epp, T. W. Balko, 2015 .

Design, synthesis and biological evaluation of succinimide derivatives as potential mechanism-based inhibitors of human leukocyte elastase, cathepsin G and proteinase 3.

H. Huang, J. Hoidal, W. Groutas, 1995, Bioorganic & medicinal chemistry.

Heterocyclic inhibitors of human leukocyte elastase: 3-Hydroxypyridazopyrimidine, 3-hydroxypyridopyrimidine and 3-hydroxyquinazoline-2,4-1H,3H0dione derivatives

W. Groutas, R. Kuang, J. Epp, 1993 .

Exploiting polymerase promiscuity: A simple colorimetric RNA polymerase assay.

C. Kao, T. Widlanski, A. D. Del Vecchio, 2000, Virology.

Fifty years of herbicide research: comparing the discovery of trifluralin and halauxifen-methyl.

J. Epp, G. D. Crouse, P. Schmitzer, 2018, Pest management science.

Dual-action inhibitors of proteolytic enzymes: potential therapeutic agents for cystic fibrosis and related ailments.

W. Groutas, J. Epp, R. Venkataraman, 1993, Bioorganic & medicinal chemistry.