M. Tanowitz

发表

Annexin A2 facilitates endocytic trafficking of antisense oligonucleotides

S. Crooke, Shiyu Wang, Xue-hai Liang, 2016, Nucleic acids research.

High-resolution visualization and quantification of nucleic acid–based therapeutics in cells and tissues using Nanoscale secondary ion mass spectrometry (NanoSIMS)

S. Young, K. Iyer, C. Bennett, 2020, Nucleic acids research.

Targeted Delivery of Antisense Oligonucleotides Through Angiotensin Type 1 Receptor.

T. P. Prakash, A. Chappell, P. Seth, 2022, Nucleic acid therapeutics.

Regulation of Neuregulin-Mediated Acetylcholine Receptor Synthesis by Protein Tyrosine Phosphatase SHP2

G. Feng, De-hua Yu, J. Si, 1999, The Journal of Neuroscience.

Agonist-Induced Desensitization and Endocytosis of G-protein-Coupled Receptors

M. Zastrow, M. Tanowitz, 2010 .

Conjugation of hydrophobic moieties enhances potency of antisense oligonucleotides in the muscle of rodents and non-human primates

F. Rigo, C. Bennett, Tae-Won Kim, 2019, Nucleic acids research.

Intra-endosomal trafficking mediated by lysobisphosphatidic acid contributes to intracellular release of phosphorothioate-modified antisense oligonucleotides

S. Crooke, Shiyu Wang, Xue-hai Liang, 2017, Nucleic acids research.

Selective tissue targeting of synthetic nucleic acid drugs.

C. Bennett, P. Seth, M. Tanowitz, 2019, The Journal of clinical investigation.

Receptor-Mediated Uptake of Phosphorothioate Antisense Oligonucleotides in Different Cell Types of the Liver.

A. J. Donner, E. Harris, T. P. Prakash, 2018, Nucleic acid therapeutics.

Targeted Delivery of Antisense Oligonucleotides Using Neurotensin Peptide.

F. Rigo, T. P. Prakash, H. Gaus, 2020, Journal of medicinal chemistry.

Intra-endosomal trafﬁcking mediated by lysobisphosphatidic acid contributes to intracellular release of phosphorothioate-modiﬁed antisense oligonucleotides

Shiyu Wang, Xue-hai Liang, Hong Sun, 2017 .

Regulation by ARIA/neuregulin of acetylcholine receptor gene transcription at the neuromuscular junction.

L. Mei, J. Si, M. Tanowitz, 1998, Life sciences.

Asialoglycoprotein receptor 1 mediates productive uptake of N-acetylgalactosamine-conjugated and unconjugated phosphorothioate antisense oligonucleotides into liver hepatocytes

T. P. Prakash, P. Seth, A. Revenko, 2017, Nucleic acids research.

Alternative Splicing Determines the Post-endocytic Sorting Fate of G-protein-coupled Receptors*

M. von Zastrow, M. Tanowitz, J. Hislop, 2008, Journal of Biological Chemistry.

Ubiquitination-independent Trafficking of G Protein-coupled Receptors to Lysosomes*

M. von Zastrow, M. Tanowitz, 2002, The Journal of Biological Chemistry.

Regulation of Neuregulin Signaling by PSD-95 Interacting with ErbB4 at CNS Synapses

D. Yang, L. Mei, W. Xiong, 2000, Neuron.

Synthesis and biological evaluation of sialyl-oligonucleotide conjugates targeting leukocyte B trans-membranal receptor CD22 as delivery agents for nucleic acid drugs.

S. Hanessian, Tianyuan Zhou, Jinghua Yu, 2016, Bioorganic & medicinal chemistry.

Site-specific replacement of phosphorothioate with alkyl phosphonate linkages enhances the therapeutic profile of gapmer ASOs by modulating interactions with cellular proteins

S. Crooke, S. Murray, Audrey Low, 2019, Nucleic acids research.

Overcoming the challenges of tissue delivery for oligonucleotide therapeutics.

S. Wiechmann, T. P. Prakash, P. Seth, 2021, Trends in pharmacological sciences.

Evaluation of Phosphorus and Non-Phosphorus Neutral Oligonucleotide Backbones for Enhancing Therapeutic Index of Gapmer Antisense Oligonucleotides.

Audrey Low, E. Swayze, P. Seth, 2021, Nucleic acid therapeutics.

Origins of the increased affinity of phosphorothioate-modified therapeutic nucleic acids for proteins.

S. Crooke, M. Nowotny, T. Vickers, 2020, Journal of the American Chemical Society.

M1 muscarinic receptor‐mediated facilitation of acetylcholine release in the rat urinary bladder.

W. D. de Groat, G. Somogyi, M. Tanowitz, 1994, The Journal of physiology.

Role of L‐ and N‐type Ca2+ channels in muscarinic receptor‐mediated facilitation of ACh and noradrenaline release in the rat urinary bladder.

W. D. de Groat, G. Somogyi, M. Tanowitz, 1997, The Journal of physiology.

Surgical denervation increases protein tyrosine phosphatase activity in skeletal muscle

L. Mei, M. Tanowitz, Hongwei Sun, 1996, Brain Research.

M1 muscarinic receptor‐induced facilitation of ACh and noradrenaline release in the rat bladder is mediated by protein kinase C.

W. D. de Groat, G. Somogyi, M. Tanowitz, 1996, The Journal of physiology.

Prejunctional facilitatory α1‐adrenoceptors in the rat urinary bladder

W. C. Groat, G. Somogyi, M. Tanowitz, 1995 .

A novel endocytic recycling signal distinguishes biological responses of Trk neurotrophin receptors.

F. Lee, Zhe-yu Chen, A. Ieraci, 2005, Molecular biology of the cell.

A Novel Endocytic Recycling Signal That Distinguishes the Membrane Trafficking of Naturally Occurring Opioid Receptors*

M. von Zastrow, M. Tanowitz, 2003, Journal of Biological Chemistry.

Association of mu-opioid receptor variants and response to citalopram treatment in major depressive disorder.

G. Jenkins, P. McGrath, S. Slager, 2010, The American journal of psychiatry.

Discovery and optimization of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1.

James G. Tarrant, M. Albertella, D. Berger, 2013, Bioorganic & medicinal chemistry letters.

Prejunctional facilitatory alpha 1-adrenoceptors in the rat urinary bladder.

W. D. de Groat, G. Somogyi, M. Tanowitz, 1995, British journal of pharmacology.

Morphological and electrophysiological analysis of the peripheral and central afferent pathways from the clitoris of the cat

W. C. Groat, M. Kawatani, M. Tanowitz, 1994, Brain Research.