M. Tanaka

发表

Synthesis and beta-lactamase inhibitory properties of 2 beta-[(1,2,3-triazol-1-yl)methyl]-2 alpha-methylpenam-3 alpha-carboxylic acid 1,1-dioxide and related triazolyl derivatives.

R. Micetich, S. Maiti, K. Ogawa, 1987, Journal of medicinal chemistry.

Orally active, nonpeptide vasopressin V2 receptor antagonists: a novel series of 1-[4-(benzoylamino)benzoyl]-2,3,4,5-tetrahydro-1H-benzazepines and related compounds.

Y. Yamamura, S. Nakamura, H. Ogawa, 1996, Journal of medicinal chemistry.

Synthesis and metal-ion binding properties of monoazathiacrown ethers.

K. Kimura, H. Ando, Y. Shibutani, 2001, The Journal of organic chemistry.

7-Chloro-5-hydroxy-1-[2-methyl-4-(2-methylbenzoyl-amino)benzoyl ]-2,3,4,5-tetrahydro-1H-1-benzazepine (OPC-41061): a potent, orally active nonpeptide arginine vasopressin V2 receptor antagonist.

Y. Yamamura, S. Nakamura, T. Onogawa, 1999, Bioorganic & medicinal chemistry.

2-Acylimino-3H-thiazoline derivatives: a novel template for platelet GPIIb/IIIa receptor antagonists.

S. Nakaike, Y. Toda, M. Sato, 2001, Bioorganic & medicinal chemistry letters.

Kinetics of metalloporphyrin formation with particular reference to the metal ion assisted mechanism

M. Tanaka, 1983 .

Lipophilic, acid-stable, adenosine deaminase-activated anti-HIV prodrugs for central nervous system delivery. 3. 6-Amino prodrugs of 2'-beta-fluoro-2',3'-dideoxyinosine.

H. Mitsuya, J. Roth, V. Marquez, 1995, Journal of medicinal chemistry.

Catalytic C-H activation by RhCl(CO)(PMe3)-hν system

T. Sakakura, M. Tanaka, 1990 .

Studies on 6-halo- and 6,6-dihalopenicillins: the rearrangement of methyl 6,6-dibromopenicillanate to 1,4-thiazepine

R. Micetich, S. Maiti, K. Ogawa, 1986 .

Design, synthesis and pharmacological evaluation of 3-benzylazetidine-2-one-based human chymase inhibitors.

Y. Aoyama, N. Naya, M. Nakajima, 2001, Bioorganic & medicinal chemistry.

Asymmetric synthesis of alpha,alpha-disubstituted alpha-amino acids using (S,S)-cyclohexane-1,2-diol as a chiral auxiliary.

M. Oba, H. Suemune, M. Tanaka, 2001, The Journal of organic chemistry.

Dehydrogenative double silylation of acetylenes with bis(hydrosilane) compounds

Y. Uchimaru, M. Tanaka, 1992 .

Molecular design of a new class of spin-labeled ribonucleosides with N-tert-butylaminoxyl radicals.

N. Koga, M. Aso, H. Suemune, 2001, Journal of Organic Chemistry.

Isoxazolidine-3,5-dione and noncyclic 1,3-dicarbonyl compounds as hypoglycemic agents.

S. Onogi, H Shinkai, S Onogi, 1998, Journal of medicinal chemistry.

Palladium-catalyzed thioesterification of alkynes with O-methyl S-phenyl thiocarbonate.

Y. Abe, R. Hua, S. Onozawa, 2001, Journal of the American Chemical Society.

A practical method for the oxidative coupling of aromatic compounds

M. Tanaka, H. Mitsuhashi, T. Wakamatsu, 1992 .

Solid-state conformation of a hybrid tripeptide between beta-amino acid; 8-aminocyclooct-4-enecarboxylic acid and 2-aminoisobutyric acid.

M. Oba, H. Suemune, M. Tanaka, 2001, Chemical & pharmaceutical bulletin.

Total syntheses of the metabolites of schizandrin

Y. Ikeya, M. Tanaka, H. Mitsuhashi, 1995 .

Total syntheses of the lignans isolated from Schisandra Chinensis

T. Ohshima, M. Tanaka, H. Mitsuhashi, 1995 .

Total synthesis of homochiral kadsurin having the natural configuration

T. Ohshima, M. Tanaka, H. Mitsuhashi, 1995 .

First total synthesis of optically pure deoxyschizandrin and wuweizisu C. The thermal stability of biaryl configuration

M. Tanaka, H. Mitsuhashi, M. Maruno, 1994 .

The stereoselective first total synthesis of isoschizandrin having the natural configuration

M. Tanaka, H. Mitsuhashi, M. Maruno, 1993 .

Synthesis of optically pure gomisin A and schizandrin: The first total synthesis of gomisin A and schizandrin having naturally occurring configurations☆

M. Tanaka, H. Mitsuhashi, T. Wakamatsu, 1992 .

Synthesis and β-Lactamase Inhibitory Properties of 2β-((1,2,3-Triazol- 1-yl)methyl)-2α-methylpenam-3α-carboxylic Acid 1,1-Dioxide and Related Triazolyl Derivatives.

R. Micetich, S. Maiti, K. Ogawa, 1988 .

Synthesis of 2β-azidomethylpenicillin-1,1-dioxides and 3β-azido-3α-methylcepham-1,1-dioxides

R. Micetich, S. Maiti, K. Ogawa, 1986 .

New Dinucleating Macrocycle, 12,24-Dihydroxy-1,6-dioxo-2,5,14,17-tetraaza(6,6)metacyclophane-13,17-diene and Its Metal Complexes.

Y. Fujii, T. Shinmyozu, H. O̅kawa, 1988 .

Nucleosides and nucleotides. 97. Synthesis of new broad spectrum antineoplastic nucleosides, 2'-deoxy-2'-methylidenecytidine (DMDC) and its derivatives.

A. Matsuda, M. Tanaka, T. Ueda, 1991, Journal of medicinal chemistry.

The Migration of Double Bond under the Neutral Conditions. The Transformation of α-Alkylidene Cyclic Carbonyl Compounds to α,β-Unsaturated Cyclic Carbonyl Compounds

M. Tanaka, H. Mitsuhashi, M. Maruno, 1994 .

Synthesis of Optically Pure Gomisi Lignans: The Total Synthesis of (+)-Schizandrin, (+)-Gomisin A, and (+)-Isoschizandrin in Naturally Occurring Forms

M. Tanaka, H. Mitsuhashi, M. Maruno, 1995 .

Palladium-Catalyzed Insertion of 1,2- and 1,4-Quinones into Si—Si Bonds and Its Application to the Modification of Si—Si-Bond-Containing Polymers.

H. Yamashita, M. Tanaka, N. P. Reddy, 1998 .

Nucleosides and nucleotides. Part 212: Practical large-scale synthesis of 1-(3-C-ethynyl-β-d-ribo-pentofuranosyl)cytosine (ECyd), a potent antitumor nucleoside. Isobutyryloxy group as an efficient anomeric leaving group in the Vorbrüggen glycosylation reaction ☆

S. Shuto, A. Matsuda, T. Asao, 2002 .

Nucleosides and nucleotides. 185. Synthesis and biological activities of 4'alpha-C-branched-chain sugar pyrimidine nucleosides.

S. Shuto, A. Matsuda, S. Shigeta, 1999, Journal of medicinal chemistry.

Nucleosides and nucleotides. 180. Synthesis and antitumor activity of nucleosides that have a hydroxylamino group instead of a hydroxyl group at the 2'- or 3'-position of the sugar moiety.

A. Matsuda, A. Ogawa, M. Tanaka, 1998, Journal of medicinal chemistry.

Antitumor activity of a novel orally effective nucleoside, 1-(2-deoxy-2-fluoro-4-thio-beta-D-arabinofuranosyl)cytosine.

A. Matsuda, Y. Yoshimura, M. Tanaka, 1998, Cancer letters.

Unusual locking of silicon chains into all-transoid conformation by pentacoordinate silicon atoms.

I. El-Sayed, Y. Hatanaka, S. Onozawa, 2001, Journal of the American Chemical Society.

Metal-requiring and non-metal - requiring catalysts in the autoxidation of methyl linoleate

M. Tanaka, M. Morita, Y. Takayama, 1976 .

Labeling of free carboxyl groups.

M. Tanaka, Y. Yasaka, 1994, Journal of chromatography. B, Biomedical applications.

Microstructure and properties of various fluorine-containing SiAlON ceramics synthesized by HIPing

S. Shimada, K. MacKenzie, H. Kiyono, 2001 .

Synthesis and photochromism of spirobenzopyran derivatives bearing an oxymethylcrown ether moiety: metal ion-induced switching between positive and negative photochromisms.

K. Kamada, K. Kimura, H. Ando, 2001, The Journal of organic chemistry.

Properties of a heparin-binding peptide derived from bovine lactoferrin.

K. Mikawa, K. Shimazaki, H. Kumura, 1998, Journal of dairy science.

Transglucosylation with 6'-chloro-6'-deoxysucrose and immobilized isomaltulose-producing microorganisms using 2,2-dimethyl-1,3-dioxolane-4-methanol and its related compounds as acceptors. Steric and chemical requirement of the glucosyl acceptor.

H. Kakinuma, M. Tanaka, H. Hashimoto, 1994, Carbohydrate research.

Nucleosides and nucleotides. 175. Structural requirements of the sugar moiety for the antitumor activities of new nucleoside antimetabolites, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine and -uracil1.

M. Fukushima, S. Shuto, A. Matsuda, 1998, Journal of medicinal chemistry.

Methylation of pyridin-2-one with methanol over γ-alumina in vapor phase

Y. Ono, M. Okamoto, M. Tanaka, 1997 .

New neplanocin analogues. VIII. Synthesis and biological activity of 6'-C-ethyl, -ethenyl, and -ethynyl derivatives of neplanocin A.

E. De Clercq, S. Shuto, A. Matsuda, 1997, Chemical & pharmaceutical bulletin.

Nucleosides and nucleotides. 141. Chemical stability of a new antitumor nucleoside, 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine in alkaline medium: formation of 2'-C-cyano-2'-deoxy-1-beta-D-ribo-pentofuranosylcytosine and its antitumor activity.

A. Matsuda, K. Hanaoka, N. Kamo, 1995, Journal of medicinal chemistry.

In vitro and in vivo antitumor activity of a novel nucleoside, 4'-thio-2'-deoxy-2'-methylidenecytidine.

A. Matsuda, H. Satoh, Y. Yoshimura, 1996, Biological & pharmaceutical bulletin.

Nucleosides and nucleotides. 122. 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosylcytosine and its derivatives. A new class of nucleoside with a broad antitumor spectrum.

N. Minakawa, A. Matsuda, K. Hanaoka, 1993, Journal of medicinal chemistry.

Nucleosides and nucleotides. 176. 2'-Deoxy-2'-hydroxylaminocytidine: a new antitumor nucleoside that inhibits DNA synthesis although it has a ribonucleoside structure.

S. Shuto, A. Matsuda, O. Inanami, 1998, Bioorganic & medicinal chemistry letters.

Development and biochemical characterization of a 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine (CNDAC)-resistant variant of the human fibrosarcoma cell line HT-1080.

Y. Endo, A. Matsuda, M. Tanaka, 1998, Cancer letters.

Nucleosides and Nucleotides. Part 152. 1-(3-C-Ethynyl-β-D-ribo- pentofuranosyl)uracil as a Broad Spectrum Antitumor Nucleoside.

A. Matsuda, H. Hattori, M. Tanaka, 1996 .

Nucleosides and nucleotides. 158. 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)-cytosine, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)uracil, and their nucleobase analogues as new potential multifunctional antitumor nucleosides with a broad spectrum of activity.

M. Fukushima, A. Matsuda, H. Hattori, 1996, Journal of medicinal chemistry.

Nucleosides and nucleotides. 100. 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosyl-cytosine (CNDAC): design of a potential mechanism-based DNA-strand-breaking antineoplastic nucleoside.

A. Matsuda, Takuma Sasaki, M. Tanaka, 1991, Journal of medicinal chemistry.

THE RNA SUBSTRATE OF THE TOBACCO RINGSPOT VIRUS DERIVED HAIRPIN RIBOZYME AND ITS DNA ANALOG ADOPT DISTINCT ORDERED STRUCTURES IN SOLUTION: AN INTRINSI C PHOTOAFFINITY STUDY

A. Favre, M. Tanaka, P. Laugâa, 1995 .

On the repair of thymidine bromohydrins, damaged nucleosides: a possible new model for the damage and repair of nucleic acids.

R. Yanada, T. Harayama, F. Yoneda, 1987, Biochemical and biophysical research communications.

3-(5-Alkyl-4-hydroxy-3-methoxy-1-naphthalenyl)-2-methyl-2-propenoic acids as orally active inhibitors of IL-1 generation.

H. Sakurai, S. Hibi, M. Tanaka, 1991, Journal of medicinal chemistry.

Antitumor effect of a novel multifunctional antitumor nucleoside, 3'-ethynylcytidine, on human cancers.

M. Fukushima, A. Matsuda, M. Tanaka, 1996, Oncology reports.

Nucleosides and Nucleotides. Part 100. 2′-C-Cyano-2′-deoxy-1-β-D- arabinofuranosylcytosine (CNDAC): Design of a Potential Mechanism- Based DNA-Strand-Breaking Antineoplastic Nucleoside.

A. Matsuda, Takuma Sasaki, M. Tanaka, 1992 .

Nucleosides and Nucleotides. Part 176. 2′-Deoxy-2′-hydroxylaminocytidine: A New Antitumor Nucleoside that Inhibits DNA Synthesis Although it has a Ribonucleoside Structure.

S. Shuto, A. Matsuda, O. Inanami, 1998 .

Enzymatic procedure for the synthesis of prostaglandin A2.

K. Sakai, H. Suemune, M. Tanaka, 1988, Chemical & pharmaceutical bulletin.

Stereo-structures of reaction products of thymidine epoxides with amines and L-amino acid ethyl esters

J. Cadet, T. Taga, K. Machida, 1988 .

Analysis of mixed parasite populations of Theileria sergenti using cDNA probes encoding a major piroplasm surface protein

C. Sugimoto, M. Onuma, H. Kubota, 1993, Parasitology.

Facile Synthesis of Alkenylsilanes (III) from Organic Halides (I) and Vinylsilanes (II) in the Presence of Triethylamine and Palladium Catalysts.

H. Yamashita, M. Tanaka, B. L. Roan, 2010 .

One-Step Synthesis of α-Hydroxy Acids via Reductive Double Carbonylation of Organic Halides.

T. Sakakura, M. Tanaka, T. Kobayashi, 1987 .

Synthesis of α-Keto Esters via Palladium-Catalyzed Double Carbonylation.

T. Sakakura, H. Yamashita, T. Hayashi, 1988 .

Reactions of PhCOPdX(PPh3)2 (X = I, Cl) with Alkyl Metals Under Carbon Monoxide. Formation of α‐Diketones and α‐Hydroxy Ketones Under Stoichiometric and Catalytic Conditions.

T. Sakakura, H. Yamashita, M. Tanaka, 1989 .

Imidacloprid and Related Compounds: Structure and Water Solubility of N-Alkyl Derivatives of Imidacloprid.

S. Kagabu, K. Yokoyama, M. Tanaka, 1998, Bioscience, biotechnology, and biochemistry.

Morphine metabolism in the opium poppy and its possible physiological function. Biochemical characterization of the morphine metabolite, bismorphine.

Y. Shimohigashi, S. Morimoto, Y. Shoyama, 2001, The Journal of biological chemistry.

Insight into acid-mediated asymmetric spirocyclization in the presence of a chiral diol.

K. Sakai, M. Aso, H. Suemune, 2000, Chemical & pharmaceutical bulletin.

The trapping of sulfenic acids from penicillin sulfoxides - use of 2,5-dimercapto-1,3,4-thiadiazole and 2,4-dimercaptopyrimidine as trapping agents.

M. Singh, R. Micetich, S. Maiti, 1985 .

Cytotoxic mechanisms of new antitumor nucleoside analogues, 3'-ethynylcytidine (ECyd) and 3'-ethynyluridine (EUrd).

M. Fukushima, Y. Wataya, A. Matsuda, 1997, Nucleic acids symposium series.

Preparation of di-O-triphenylmethyl-(trityl-) cyclomaltohexaoses and -cyclomaltoheptaoses and characterization of three positional isomers of each by the "hex-5-enose degradation".

K. Koizumi, T. Tanimoto, M. Tanaka, 1992, Carbohydrate research.

Distribution, excretion, and metabolism of 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitrosourea (ACNU) in rats and mice after iv administration.

K. Nakamura, M. Tanaka, E. Nakajima, 1980, Cancer treatment reports.

Synthesis of 2,8-disubstituted imidazo[1,5-a]pyrimidines with potent antitumor activity.

H. Takayanagi, M. Tanaka, N. Nagata, 1999, Journal of medicinal chemistry.

Synthesis and biological evaluation of all A-ring stereoisomers of 5,6-trans-2-methyl-1,25-dihydroxyvitamin D(3) and their 20-epimers: possible binding modes of potent A-ring analogues to vitamin D receptor.

N. Miyata, K. Nakagawa, T. Okano, 2001, Chemistry and Biology.

Synthesis of iridolactones isolated from Silver vine

M. Tanaka, H. Mitsuhashi, T. Wakamatsu, 1992 .

Palladium- or Platinum-Catalyzed Novel Double Silylation of α- Diketones or a Benzoylformate with Hexamethyldisilane Affording 1,2- Bis(siloxy)ethenes or a Double Silylated Tartrate Derivative.

H. Yamashita, M. Tanaka, N. P. Reddy, 1993 .

Synthesis of a 3,1-Benzoxazin-4-one, 2,4(1H,3H)-Quinolinediones, and 2,4(1H,3H)-Quinazolinediones from the Reaction of Phosphoryl-Stabilized Anions Containing no a-Hydrogen Atoms with Isatoic Anhydride

M. Ogata, I. Hirao, T. Minami, 1982 .