L. Monjas

发表

Rational Adaptation of L3MBTL1 Inhibitors to Create Small‐Molecule Cbx7 Antagonists

J. Wulff, A. Hirsch, Natalia Milosevich, 2019, ChemMedChem.

Α-aryl-N-alkyl nitrones, as potential agents for stroke treatment: synthesis, theoretical calculations, antioxidant, anti-inflammatory, neuroprotective, and brain-blood barrier permeability properties.

D. Hadjipavlou-Litina, A. Alcázar, Abdelouahid Samadi, 2012, Journal of medicinal chemistry.

Insight into the complete substrate-binding pocket of ThiT by chemical and genetic mutations.

S. Marrink, I. Faustino, D. Slotboom, 2017, MedChemComm.

Studying thiamine binding to ThiT using chemical and biochemical mutations

S. Marrink, I. Faustino, D. Slotboom, 2016 .

Design and synthesis of thiamine analogues to study their binding to the ECF transporter for thiamine in bacteria

D. Slotboom, A. Hirsch, R. Oudshoorn, 2016 .

Structure‐Based Design of Potent Small‐Molecule Binders to the S‐Component of the ECF Transporter for Thiamine

A. Guskov, D. Slotboom, Guus B. Erkens, 2015, Chembiochem : a European journal of chemical biology.

Tunable energy and mass renormalization from homothetic Quantum dot arrays

A. Arnau, J. Ortega, A. Hirsch, 2019 .

A combinatorial approach for the discovery of drug-like inhibitors of 15-lipoxygenase-1.

F. Dekker, N. Eleftheriadis, A. Hirsch, 2019, European journal of medicinal chemistry.

"Clicking" fragment leads to novel dual-binding cholinesterase inhibitors.

A. Zawadzka, A. Hirsch, Z. Czarnocki, 2021, Bioorganic & medicinal chemistry.

Surface state tunable energy and mass renormalization from homothetic quantum dot arrays.

A. Arnau, J. Ortega, A. Hirsch, 2019, Nanoscale.

Low-Dimensional Metal–Organic Coordination Structures on Graphene

R. Havenith, A. Hirsch, M. Enache, 2019, The journal of physical chemistry. C, Nanomaterials and interfaces.

Synthesis, biological assessment, and molecular modeling of racemic 7-aryl-9,10,11,12-tetrahydro-7H-benzo[7,8]chromeno[2,3-b]quinolin-8-amines as potential drugs for the treatment of Alzheimer's disease.

C. Pérez, Ignacio Moraleda, I. Iriepa, 2012, European journal of medicinal chemistry.

New tacrine-4-oxo-4H-chromene hybrids as multifunctional agents for the treatment of Alzheimer's disease, with cholinergic, antioxidant, and β-amyloid-reducing properties.

Jörg Rademann, C. Pérez, J. Rademann, 2012, Journal of medicinal chemistry.

Benzothiazepine CGP37157 and its isosteric 2'-methyl analogue provide neuroprotection and block cell calcium entry.

C. Pérez, R. León, Manuela G. López, 2012, ACS chemical neuroscience.

Validation of a homology model of Mycobacterium tuberculosis DXS: rationalization of observed activities of thiamine derivatives as potent inhibitors of two orthologues of DXS.

D. Hawksley, M. Fischer, F. Leeper, 2015, Organic & biomolecular chemistry.

Dynamic Combinatorial Chemistry to Identify Binders of ThiT, an S‐Component of the Energy‐Coupling Factor Transporter for Thiamine

I. Setyawati, D. Slotboom, A. Hirsch, 2017, ChemMedChem.

Multipotent, permeable drug ASS234 inhibits Aβ aggregation, possesses antioxidant properties and protects from Aβ-induced apoptosis in vitro.

C. Pérez, Irene Bolea, Abdelouahid Samadi, 2013, Current Alzheimer research.

Unveiling Adatoms in On-Surface Reactions: Combining Scanning Probe Microscopy with van’t Hoff Plots

D. J. Mowbray, A. Hirsch, M. Stöhr, 2021, The journal of physical chemistry. C, Nanomaterials and interfaces.

Comparing the Self‐Assembly of Sexiphenyl‐Dicarbonitrile on Graphite and Graphene on Cu(111)

R. Havenith, A. Hirsch, M. Enache, 2019, Chemistry.

Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia.

C. Pérez, R. León, Manuela G. López, 2017, European journal of medicinal chemistry.

Anthraquinone derivatives as ADP-competitive inhibitors of liver pyruvate kinase.

J. Borén, M. Uhlén, A. Mardinoğlu, 2022, European journal of medicinal chemistry.