Setshaba D. Khanye

发表

New Quinolone-Based Thiosemicarbazones Showing Activity Against Plasmodium falciparum and Mycobacterium tuberculosis

D. Warner, Richard M. Beteck, R. Seldon, 2019, Molecules.

Novobiocin–ferrocene conjugates possessing anticancer and antiplasmodial activity independent of HSP90 inhibition

A. Edkins, M. Isaacs, Jason N Sterrenberg, 2018, JBIC Journal of Biological Inorganic Chemistry.

Quinolone-isoniazid hybrids: synthesis and preliminary in vitro cytotoxicity and anti-tuberculosis evaluation.

D. Warner, Richard M. Beteck, L. Legoabe, 2019, MedChemComm.

Butyldiphenylphosphine oxide

Bernard Omondi, E. M. Coyanis, A. Lemmerer, 2007 .

Synthesis, Structure and In Vitro Anti-Trypanosomal Activity of Non-Toxic Arylpyrrole-Based Chalcone Derivatives

Clinton G. L. Veale, M. Isaacs, H. Hoppe, 2020, Molecules.

Coumarin-Annulated Ferrocenyl 1,3-Oxazine Derivatives Possessing In Vitro Antimalarial and Antitrypanosomal Potency

A. Edkins, Laura M. K. Dingle, Dustin Laming, 2021, Molecules.

Anti-Trypanosomal and Antimalarial Properties of Tetralone Derivatives and Structurally Related Benzocycloalkanones

M. Isaacs, Richard M. Beteck, L. Legoabe, 2019, Medicina.

A ring-closing metathesis approach to eight-membered benzannelated scaffolds and subsequent internal alkene isomerizations

B. Aderibigbe, W. V. Otterlo, I. Green, 2013 .

Synthesis of unsaturated 1,4-heteroatom-containing benzo-fused heterocycles using a sequential isomerization–ring-closing metathesis strategy

W. V. Otterlo, C. B. Koning, J. Michael, 2009 .

Isomerization and ring-closing metathesis for the synthesis of 6-, 7- and 8-membered benzo- and pyrido-fused N,N-, N,O- and N,S-heterocycles

B. Aderibigbe, D. Billing, W. V. Otterlo, 2004 .

The in Vitro Antiplasmodial and Antiproliferative Activity of New Ferrocene‐Based α‐Aminocresols Targeting Hemozoin Inhibition and DNA Interaction

Dale Taylor, C. Biot, A. Edkins, 2020, Chembiochem : a European journal of chemical biology.

Design, synthesis and biological evaluation of mono- and bisquinoline methanamine derivatives as potential antiplasmodial agents.

Richard M. Beteck, Dustin Laming, H. Hoppe, 2021, Bioorganic & medicinal chemistry letters.

Unexpected transformations of 3-(bromoacetyl)coumarin provides new evidence for the mechanism of thiol mediated dehalogenation of α-halocarbonyls

Clinton G. L. Veale, Setshaba D. Khanye, Faith N. Magwenzi, 2017 .

Synthesis and in vitro antiprotozoal evaluation of novel metronidazole-Schiff base hybrids.

M. Isaacs, K. Land, Richard M. Beteck, 2022, Archiv der Pharmazie.

Application of the Morita-Baylis-Hillman reaction in the synthesis of 3-[(N-cycloalkylbenzamido)methyl]-2-quinolones as potential HIV-1 integrase inhibitors.

P. T. Kaye, M. Isaacs, F. H. Kriel, 2017, Bioorganic chemistry.

Propylphosphonic acid anhydride–mediated amidation of Morita–Baylis–Hillman–derived indolizine-2-carboxylic acids

P. T. Kaye, D. Warner, M. Isaacs, 2021 .

Expanding the SAR of Nontoxic Antiplasmodial Indolyl‐3‐ethanone Ethers and Thioethers

Clinton G. L. Veale, Dale Taylor, A. Edkins, 2018, ChemMedChem.

Organometallic Chemistry of Drugs Based on Iron

C. Biot, Setshaba D. Khanye, Mziyanda Mbaba, 2021, Reference Module in Chemistry, Molecular Sciences and Chemical Engineering.

Facile synthesis and biological evaluation of assorted indolyl-3-amides and esters from a single, stable carbonyl nitrile intermediate

Clinton G. L. Veale, Peter J. Smith, A. Edkins, 2015 .

Synthesis and in vitro evaluation of gold(I) thiosemicarbazone complexes for antimalarial activity.

J. Gut, P. Rosenthal, K. Chibale, 2010, Journal of inorganic biochemistry.

Ferrocenylthiosemicarbazones conjugated to a poly(propyleneimine) dendrimer scaffold: Synthesis and in vitro antimalarial activity

J. Gut, P. Rosenthal, K. Chibale, 2011 .

Synthesis, in vitro cytotoxicity and trypanocidal evaluation of novel 1,3,6-substituted non-fluoroquinolones

M. Isaacs, Richard M. Beteck, H. Hoppe, 2018 .

Synthesis, antiplasmodial and antitrypanosomal evaluation of a series of novel 2-oxoquinoline-based thiosemicarbazone derivatives

R. Krause, M. Isaacs, Richard M. Beteck, 2018 .

Repurposing a polymer precursor: Synthesis and in vitro medicinal potential of ferrocenyl 1,3-benzoxazine derivatives.

Dale Taylor, A. Edkins, Laura M. K. Dingle, 2019, European journal of medicinal chemistry.

Ferrocenyl and organic novobiocin derivatives: Synthesis and their in vitro biological activity.

A. Edkins, M. Isaacs, N. Boel, 2017, Journal of inorganic biochemistry.

Synthesis and in vitro antimalarial and antitubercular activity of gold(III) complexes containing thiosemicarbazone ligands

J. Gut, P. Rosenthal, K. Chibale, 2011 .

Gold(I) derived thiosemicarbazone complexes with rare halogen-halogen interaction-reduction of [Au(damp-C1,N)Cl2].

K. Chibale, Gregory S. Smith, Setshaba D. Khanye, 2010, Dalton transactions.

A New Synthetic Method for Tetraazatricyclic Derivatives and Evaluation of Their Biological Properties

K. Lobb, Z. Tshentu, C. Frost, 2018, ChemistrySelect.

Cinnamoyl-Oxaborole Amides: Synthesis and Their in Vitro Biological Activity

D. Warner, M. Isaacs, K. Land, 2018, Molecules.

Easy-To-Synthesize Spirocyclic Compounds Possess Remarkable in Vivo Activity against Mycobacterium tuberculosis.

Katrina A. Badiola, M. Todd, P. Rutledge, 2018, Journal of medicinal chemistry.

Indolyl-3-ethanone-α-thioethers: A promising new class of non-toxic antimalarial agents.

Clinton G. L. Veale, M. Isaacs, H. Hoppe, 2016, European journal of medicinal chemistry.

Arylquinolinecarboxamides: Synthesis, in vitro and in silico studies against Mycobacterium tuberculosis

K. Lobb, D. Warner, Richard M. Beteck, 2021, Journal of Heterocyclic Chemistry.