Chao Yao

发表

SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression

M. Weirauch, B. Namjou, J. Harley, 2021, Nature communications.

SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression

M. Weirauch, B. Namjou, J. Harley, 2020, bioRxiv.

The NCF1 variant p.R90H aggravates autoimmunity by facilitating the activation of plasmacytoid dendritic cells

N. Shen, Jianyang Ma, Chien-Liang Liu, 2022, The Journal of clinical investigation.

Lupus enhancer risk variant causes dysregulation of IRF8 through cooperative lncRNA and DNA methylation machinery

M. Weirauch, B. Namjou, J. Harley, 2022, Nature Communications.

The transcription factor Zeb2 drives differentiation of age-associated B cells

C. Vinuesa, N. Shen, Haibo Zhou, 2021, bioRxiv.

The MicroRNA miR-22 Represses Th17 Cell Pathogenicity by Targeting PTEN-Regulated Pathways

Yuanjia Tang, N. Shen, Wenfei Jin, 2020, ImmunoHorizons.

Inhibition of Glycolysis in Pathogenic TH17 Cells through Targeting a miR-21–Peli1–c-Rel Pathway Prevents Autoimmunity

N. Shen, Wenfei Jin, Zhijun Han, 2020, The Journal of Immunology.

Targeting PTEN-Regulated Pathways Represses Th17 Cell Pathogenicity by miR-22 The MicroRNA

Yuanjia Tang, N. Shen, Zhijun Han, 2020 .

Deregulation of TGF-β1 signaling induces glycolysis by chromatin remodeling in pathogenic TH17 cells

N. Shen, Wenfei Jin, Zhijun Han, 2019 .

TGF-β1 signaling remodels TH17 cell chromatin architecture for metabolic reprogramming

Yuanjia Tang, N. Shen, J. Qian, 2018 .

MiR-21 Regulates Metabolic Adaptation of TH17 Cells during Autoimmunity and Host Defence

Yuanjia Tang, N. Shen, J. Qian, 2018 .

MicroRNA-21 Regulates Metabolic Adaptation of Pathogenic TH17 cells and Controls Autoimmune Inflammation

Yuanjia Tang, N. Shen, J. Qian, 2017, bioRxiv.

Long non-coding RNA expression profiles in neutrophils revealed potential biomarker for prediction of renal involvement in SLE patients.

N. Shen, Jianyang Ma, Z. Yin, 2020, Rheumatology.

CRISPRa screen on a genetic risk locus shared by multiple autoimmune diseases identifies a dysfunctional enhancer that affects IRF8 expression through cooperative lncRNA and DNA methylation machinery

M. Weirauch, B. Namjou, J. Harley, 2021, bioRxiv.

Identification of Renal Long Non-coding RNA RP11-2B6.2 as a Positive Regulator of Type I Interferon Signaling Pathway in Lupus Nephritis

Lingling Wu, N. Shen, Jianyang Ma, 2019, Front. Immunol..

Association of Abnormal Elevations in IFIT3 With Overactive Cyclic GMP‐AMP Synthase/Stimulator of Interferon Genes Signaling in Human Systemic Lupus Erythematosus Monocytes

Lingling Wu, N. Shen, J. Qian, 2018, Arthritis & Rheumatology.

Amelioration of Autoimmunity in a Lupus Mouse Model by Modulation of T‐Bet–Promoted Energy Metabolism in Pathogenic Age/Autoimmune‐Associated B Cells

Z. Yin, Z. Ye, H. Ding, 2023 .

The transcription factor Zeb2 drives formation of age-associated B cells

C. Vinuesa, N. Shen, Haibo Zhou, 2021, bioRxiv.

Involvement of Transcriptional Factor Pbx1 in Peripheral B Cell Homeostasis to Constrain Lupus Autoimmunity

Haibo Zhou, J. Qian, Z. Yin, 2023, Arthritis & rheumatology.

Association of Abnormal Elevations in IFIT3 With Overactive Cyclic GMP‐AMP Synthase/Stimulator of Interferon Genes Signaling in Human Systemic Lupus Erythematosus Monocytes

Lingling Wu, N. Shen, J. Qian, 2018, Arthritis & rheumatology.

Amelioration of Autoimmunity in a Lupus Mouse Model by Modulation of T‐Bet–Promoted Energy Metabolism in Pathogenic Age/Autoimmune‐Associated B Cells

Z. Yin, Z. Ye, Sheng Chen, 2022, Arthritis & rheumatology.

The transcription factor ZEB2 drives formation of age-associated B cells

M. Weirauch, Jianyang Ma, L. Kottyan, 2021, bioRxiv.