A. Zhukov

发表

Discovery of HTL6641, a dual orexin receptor antagonist with differentiated pharmacodynamic properties

M. Congreve, C. Langmead, J. Errey, 2015 .

X‐Ray Crystallography and Free Energy Calculations Reveal the Binding Mechanism of A2A Adenosine Receptor Antagonists†

M. Congreve, J. Mason, J. Åqvist, 2020, Angewandte Chemie.

Protein Panels Label-Free Primary Screening and Affinity Ranking of Fragment Libraries Using Parallel Analysis of

Robert Karlsson, Magnus Björsne, Maria Ivarsson, 2013 .

X‐Ray Crystallography and Free Energy Calculations Reveal the Binding Mechanism of A2A Adenosine Receptor Antagonists†

M. Congreve, J. Mason, J. Åqvist, 2019, Angewandte Chemie.

Relationship between cytochrome P450 catalytic cycling and stability: fast degradation of ethanol-inducible cytochrome P450 2E1 (CYP2E1) in hepatoma cells is abolished by inactivation of its electron donor NADPH-cytochrome P450 reductase.

M. Ingelman-Sundberg, A. Zhukov, Magnus Ingelman-Sundberg, 1999, The Biochemical journal.

Cytochrome P-450 spin state and leakiness of the monooxygenase pathway.

O. Ristau, J. Blanck, K. Ruckpaul, 1991, Xenobiotica; the fate of foreign compounds in biological systems.

The properties of thermostabilised G protein-coupled receptors (StaRs) and their use in drug discovery

Nathan Robertson, Ali Jazayeri, Christopher J. Langmead, 2011, Neuropharmacology.

Purification of Stabilized GPCRs for Structural and Biophysical Analyses.

A. Doré, J. Errey, F. Marshall, 2015, Methods in molecular biology.

Transcriptional and Post-Translational Regulation of CYP 1 A 1 by Primaquine

M. Ingelman-Sundberg, M. Backlund, A. Zhukov, 2001 .

Transcriptional and post-translational regulation of CYP1A1 by primaquine.

M. Ingelman-Sundberg, M. Backlund, A. Zhukov, 2001, The Journal of pharmacology and experimental therapeutics.

Selective fast degradation of cytochrome P-450 2E1 in serum-deprived hepatoma cells by a mechanism sensitive to inhibitors of vesicular transport.

M. Ingelman-Sundberg, A. Zhukov, Magnus Ingelman-Sundberg, 1997, European journal of biochemistry.

Purification and characterization of hepsin from rat liver microsomes.

M. Ingelman-Sundberg, U. Hellman, A. Zhukov, 1997, Biochimica et biophysica acta.

Discovery of 1,2,4-Triazine Derivatives as Adenosine A2A Antagonists using Structure Based Drug Design

Jonathan S. Mason, Christopher J. Langmead, S. P. Andrews, 2012, Journal of medicinal chemistry.

Ethanol-inducible cytochrome P4502E1: regulation, enzymology and molecular biology.

M. Ingelman-Sundberg, M. Ronis, K. Lindros, 1994, Alcohol and alcoholism (Oxford, Oxfordshire). Supplement.

Structural insight into allosteric modulation of protease-activated receptor 2

Patrik Johansson, Ali Jazayeri, Christoph Grebner, 2017, Nature.

Biophysical Mapping of the Adenosine A2A Receptor

Nathan Robertson, Jonathan S. Mason, S. P. Andrews, 2011, Journal of medicinal chemistry.

Monoclonal anti-β1-adrenergic receptor antibodies activate G protein signaling in the absence of β-arrestin recruitment

C. J. Hutchings, C. Langmead, F. Marshall, 2014, mAbs.

Impact of protein–ligand solvation and desolvation on transition state thermodynamic properties of adenosine A2A ligand binding kinetics

Francesca Deflorian, Andrea Bortolato, Stephanie Federico, 2017, In Silico Pharmacology.

Biosensor‐based affinities and binding kinetics of small molecule antagonists to the adenosine A2A receptor reconstituted in HDL like particles

E. Segala, J. Errey, R. Cooke, 2015, FEBS letters.

Article pubs.acs.org/jmc Identification of Novel Adenosine A 2A Receptor Antagonists by Virtual Screening

Nathan Robertson, Jonathan S. Mason, Christopher J. Langmead, 2022 .

EFFECT OF DOPAMINE AND LONG-CHAIN N-ACYLETHANOLAMINES ON STEROIDOGENESIS IN RAT ADRENAL GLAND IN VITRO

A. Zhukov, O. Kovzun, A. Mikosha, 1998 .

Regulation of Cytochromes P450 by Substrate Interactions

M. Ingelman-Sundberg, S. Mkrtchian, E. Eliasson, 1994 .

X‐Ray Crystallography and Free Energy Calculations Reveal the Binding Mechanism of A2A Adenosine Receptor Antagonists†

M. Congreve, J. Mason, J. Åqvist, 2019, Angewandte Chemie.

Optimizing the surface plasmon resonance/mass spectrometry interface for functional proteomics applications: How to avoid and utilize nonspecific adsorption

Jos Buijs, Andrei Zhukov, Sven Oscarsson, 2006, Proteomics.

Statistical aspects of van't Hoff analysis: a simulation study

R. Karlsson, A. Zhukov, 2007, Journal of molecular recognition : JMR.

Integration of surface plasmon resonance with mass spectrometry: automated ligand fishing and sample preparation for MALDI MS using a Biacore 3000 biosensor.

Jos Buijs, Andrei Zhukov, Martin Schürenberg, 2004, Journal of biomolecular techniques : JBT.

Purification and characterization of two membrane bound serine proteinases from rat liver microsomes active in degradation of cytochrome P450.

M. Ingelman-Sundberg, A. Zhukov, V. Werlinder, 1993, Biochemical and biophysical research communications.

Complete stoichiometry of free NADPH oxidation in liver microsomes.

A. Zhukov, A. Archakov, 1982, Biochemical and biophysical research communications.

Label-Free Primary Screening and Affinity Ranking of Fragment Libraries Using Parallel Analysis of Protein Panels

Magnus Björsne, Tomas Fex, Johan Gottfries, 2008, Journal of biomolecular screening.