Naoki Aizawa

发表

Effects of TRPV4 cation channel activation on the primary bladder afferent activities of the rat

Y. Homma, J. Wyndaele, Y. Igawa, 2012, Neurourology and urodynamics.

Bladder sensation evaluation of a carrageenan‐induced chronic prostatitis model using a direct measurement of the bladder mechanosensitive single‐unit afferent nerve activity

T. Fujita, T. Yamanishi, Naoki Aizawa, 2020, Neurourology and urodynamics.

GUANYLATE CYCLASE AND P2X PURINOCEPTOR SIGNALLING PATHWAYS CONTRIBUTE TO UROTHELIUM-DERIVED INHIBITION OF β-ADRENOCEPTOR-MEDIATED RELAXATION IN HUMAN DETRUSOR SMOOTH MUSCLE

Y. Homma, H. Fukuhara, Y. Igawa, 2016 .

Effects of mirabegron, a novel β3-adrenoceptor agonist, on primary bladder afferent activity and bladder microcontractions in rats compared with the effects of oxybutynin.

Y. Homma, Y. Igawa, Naoki Aizawa, 2012, European urology.

Beta3-Adrenoceptor Agonists: Possible Role in the Treatment of Overactive Bladder

Y. Homma, Y. Igawa, Naoki Aizawa, 2010, Korean journal of urology.

Effects of Sildenafil, a Phosphodiesterase Type 5 Inhibitor, on the Primary Single Afferent Activity of the Rat Bladder

H. Kume, Y. Homma, H. Fukuhara, 2017, Lower urinary tract symptoms.

The TRPM8 channel as a potential therapeutic target for bladder hypersensitive disorders

T. Fujita, Naoki Aizawa, 2022, Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi.

Rat Bladders Augmented with a Novel Bovine Pericardium‐Derived Biomaterial Reconstruct Functional Tissue Structures

Tetsuya Imamura, O. Nishizawa, O. Ishizuka, 2010, Lower urinary tract symptoms.

Living Anionic Addition Reaction of 1,1-Diphenylethylene Derivatives: One-Pot Synthesis of ABC-type Chain-End Sequence-Controlled Polymers.

S. Uchida, M. Nagao, Raita Goseki, 2021, Journal of the American Chemical Society.

May perioperative ultrasound‐guided pelvic floor muscle training promote early recovery of urinary continence after robot‐assisted radical prostatectomy?

H. Kume, Y. Homma, H. Sanada, 2018, Neurourology and urodynamics.

Attenuated lipopolysaccharide-induced inflammatory bladder hypersensitivity in mice deficient of transient receptor potential ankilin1

H. Kume, Y. Homma, T. Nakagawa, 2018, Scientific Reports.

Cold environmental stress induces detrusor overactivity via resiniferatoxin‐sensitive nerves in conscious rats

Tetsuya Imamura, O. Nishizawa, O. Ishizuka, 2008, Neurourology and urodynamics.

Effects of phenazopyridine on rat bladder primary afferent activity, and comparison with lidocaine and acetaminophen

J. Wyndaele, Naoki Aizawa, 2010, Neurourology and urodynamics.

Differences in Brain Hemodynamics in Response to Achromatic and Chromatic Cards of the Rorschach

M. Jung, D. Saito, C. Uchiumi, 2016, Rorschachiana.

Effects of natriuretic peptides on intracavernous pressure and blood pressure in conscious rats.

K. Andersson, Y. Igawa, O. Nishizawa, 2008, The journal of sexual medicine.

Effects of nitric oxide on the primary bladder afferent activities of the rat with and without intravesical acrolein treatment.

J. Wyndaele, Y. Igawa, O. Nishizawa, 2011, European urology.

Diagnostic value of urinary CXCL10 as a biomarker for predicting Hunner type interstitial cystitis

Y. Homma, H. Fukuhara, A. Nomiya, 2018, Neurourology and urodynamics.

Long-term caloric restriction in rats may prevent age related impairment of in vitro bladder function.

Y. Homma, H. Fukuhara, Y. Kubota, 2015, The Journal of urology.

Inhibitory effects of phosphodiesterase 5 inhibitor, tadalafil, on mechanosensitive bladder afferent nerve activities of the rat, and on acrolein‐induced hyperactivity of these nerves

J. Wyndaele, Y. Igawa, T. Minagawa, 2012, BJU international.

Effects of L‐arginine, mirabegron, and oxybutynin on the primary bladder afferent nerve activities synchronized with reflexic, rhythmic bladder contractions in the rat

Y. Homma, Y. Igawa, Naoki Aizawa, 2015, Neurourology and urodynamics.

Comparison of the effects of oestrogen deficiency and old age on primary bladder afferent activity and voiding behaviour in the ageing female rat

T. Downs, J. Wyndaele, K. Andersson, 2011, BJU international.

Differentiation of smooth muscle cells from human amniotic mesenchymal cells implanted in the freeze-injured mouse urinary bladder.

Y. Igawa, Tetsuya Imamura, O. Nishizawa, 2010, European urology.

Gosha‐jinki‐gan reduces transmitter proteins and sensory receptors associated with C fiber activation induced by acetic acid in rat urinary bladder

Tetsuya Imamura, O. Nishizawa, O. Ishizuka, 2008, Neurourology and urodynamics.

Functional roles of bladder α1‐adrenoceptors in the activation of single‐unit primary bladder afferent activity in rats

Y. Homma, H. Fukuhara, Y. Igawa, 2016, BJU International.

Lacking transient receptor potential melastatin 2 attenuates lipopolysaccharide‐induced bladder inflammation and its associated hypersensitivity in mice

H. Kume, Y. Homma, T. Nakagawa, 2020, International journal of urology : official journal of the Japanese Urological Association.

β3‐Adrenoceptors in the normal and diseased urinary bladder—What are the open questions?

M. Michel, Y. Igawa, Naoki Aizawa, 2019, British journal of pharmacology.

Autologous bone‐marrow‐derived mesenchymal stem cell transplantation into injured rat urethral sphincter

Y. Igawa, Tetsuya Imamura, O. Nishizawa, 2010, International journal of urology : official journal of the Japanese Urological Association.

Influence of urethane‐anesthesia on the effect of resiniferatoxin treatment on bladder function in rats with spinal cord injury

Y. Homma, Y. Igawa, Naoki Aizawa, 2015, Neurourology and urodynamics.

Direct influence of systemic desensitization by resiniferatoxin on the activities of Aδ‐ and C‐fibers in the rat primary bladder mechanosensitive afferent nerves

Y. Homma, H. Fukuhara, Y. Igawa, 2016, International journal of urology : official journal of the Japanese Urological Association.

Pathophysiological changes of the lower urinary tract behind voiding dysfunction in streptozotocin-induced long-term diabetic rats

H. Kume, Kazuki Masuda, T. Okegawa, 2020, Scientific Reports.

Preventive Effects of Long-Term Caloric Restriction on Aging Related In Vivo Bladder Dysfunction and Molecular Biological Changes in the Bladder and Dorsal Root Ganglia in Rats.

Y. Homma, H. Fukuhara, T. Kojima, 2016, The Journal of urology.

KPR-2579, a novel TRPM8 antagonist, inhibits acetic-acid-induced bladder hyperactivity via mechanosensitive afferent C-fibers in rats

Y. Homma, O. Nakanishi, Y. Igawa, 2017 .

EFFECTS OF TRPM8 CHANNELS’ INHIBITION ON CONCIOUS CYSTOMETRY AND SINGLE-UNIT MECHANOSENSITIVE BLADDER AFFERENT ACTIVITIES IN NOVEL EX VIVO MODEL OF THE RAT

Y. Homma, Y. Kubota, N. Takahashi, 2013 .

Stimulation of skin menthol receptors stimulates detrusor activity in conscious rats

K. Andersson, Y. Igawa, Tetsuya Imamura, 2010, Neurourology and urodynamics.

Attenuated lipopolysaccharide-induced inflammatory bladder hypersensitivity in mice deficient of transient receptor potential ankilin1

H. Kume, Y. Homma, T. Nakagawa, 2018, Scientific Reports.

The role of transient receptor potential ankyrin 1 (TRPA1) channel in activation of single unit mechanosensitive bladder afferent activities in the rat

J. Wyndaele, Y. Igawa, T. Minagawa, 2014, Neurourology and urodynamics.

Mechanisms of pelvic organ cross-talk: 2. Impact of colorectal distention on afferent nerve activity of the rat bladder.

J. Wyndaele, M. Wyndaele, Y. Igawa, 2013, The Journal of urology.

Pathophysiology of the underactive bladder

Y. Igawa, Naoki Aizawa, 2017, Investigative and clinical urology.

Beta 3-Adrenoceptor Agonists : Possible Role in the Treatment of Overactive Bladder

Y. Homma, Y. Igawa, Naoki Aizawa, 2010 .

Inhibition of peripheral FAAH depresses activities of bladder mechanosensitive nerve fibers of the rat.

Y. Homma, Y. Igawa, P. Hedlund, 2014, The Journal of urology.

URB937, a peripherally restricted inhibitor for fatty acid amide hydrolase, reduces prostaglandin E2‐induced bladder overactivity and hyperactivity of bladder mechano‐afferent nerve fibres in rats

Y. Homma, F. Montorsi, G. Gandaglia, 2016, BJU international.

Characteristics of the mechanosensitive bladder afferent activities in relation with microcontractions in male rats with bladder outlet obstruction

Y. Homma, H. Fukuhara, K. Andersson, 2017, Scientific Reports.

Effects of CL316,243, a β3‐adrenoceptor agonist, and intravesical prostaglandin E2 on the primary bladder afferent activity of the rat

J. Wyndaele, Y. Igawa, O. Nishizawa, 2010, Neurourology and urodynamics.

Y. Homma, T. Kojima, Masafumi Ito, 2018, Scientific Reports.

Synergic Suppressive Effect of Silodosin and Imidafenacin on Non‐Voiding Bladder Contractions in Male Rats with Subacute Bladder Outlet Obstruction

H. Kume, Y. Homma, H. Fukuhara, 2017, Lower urinary tract symptoms.

COMPARISON OF THE EFFECTS OF MIRABEGRON, A NOVEL BETA3-ADRENOCEPTOR AGONIST, WITH THE ANTICHOLINERGIC AGENT, OXYBUTININ, ON PRIMARY BLADDER AFFERENT ACTIVITY AND BLADDER MICROCONTRACTIONS IN RATS

Y. Homma, Y. Igawa, Naoki Aizawa, 2012 .

Role of α1‐adrenergic receptors in detrusor overactivity induced by cold stress in conscious rats

K. Andersson, Y. Igawa, Tetsuya Imamura, 2009, Neurourology and urodynamics.

Role of 5-HT receptor antagonists in mediating intracavernous pressure response induced by fluvoxamine in conscious rats.

Y. Igawa, O. Nishizawa, O. Ishizuka, 2007, The journal of sexual medicine.

Inhibitory effects of silodosin on the bladder mechanosensitive afferent activities and their relation with bladder myogenic contractions in male rats with bladder outlet obstruction

H. Kume, Y. Homma, H. Fukuhara, 2018, Neurourology and urodynamics.

Toll-like receptor 7 is overexpressed in the bladder of Hunner-type interstitial cystitis, and its activation in the mouse bladder can induce cystitis and bladder pain

Y. Homma, N. Masumori, K. Andersson, 2017, Pain.

Characteristics of lower urinary tract dysfunction and bladder afferent nerve properties in type 2 diabetic goto-kakizaki rats.

Y. Homma, Y. Igawa, Naoki Aizawa, 2013, The Journal of urology.

KPR-5714, a Novel Transient Receptor Potential Melastatin 8 Antagonist, Improves Overactive Bladder via Inhibition of Bladder Afferent Hyperactivity in Rats

O. Nakanishi, Y. Igawa, Hideaki Hirasawa, 2020, The Journal of Pharmacology and Experimental Therapeutics.

RQ‐00434739, a novel TRPM8 antagonist, inhibits prostaglandin E2‐induced hyperactivity of the primary bladder afferent nerves in rats

H. Kume, Y. Homma, Hiroyuki Ohshiro, 2019, Life sciences.

KPR‐2579, a novel TRPM8 antagonist, inhibits acetic acid‐induced bladder afferent hyperactivity in rats

H. Kume, Y. Homma, O. Nakanishi, 2018, Neurourology and urodynamics.

Functional role of the transient receptor potential melastatin 8 (TRPM8) ion channel in the urinary bladder assessed by conscious cystometry and ex vivo measurements of single‐unit mechanosensitive bladder afferent activities in the rat

Y. Homma, H. Fukuhara, Y. Kubota, 2016, BJU international.

Selective inhibitory effect of imidafenacin and 5-hydroxymethyl tolterodine on capsaicin sensitive C fibers of the primary bladder mechanosensitive afferent nerves in the rat.

Y. Homma, H. Fukuhara, Motofumi Suzuki, 2015, The Journal of urology.

SYNERGIC SUPRESSIVE EFFECT OF THE COMBINATION THERAPY WITH SILODOSIN AND IMIDAFENACIN ON NON-VOIDING CONTRACTIONS IN MALE RATS WITH SUB-ACUTE BLADDER OUTLET OBSTRUCTION

Y. Homma, Y. Igawa, Naoki Aizawa, 2013 .

Y. Homma, T. Kojima, Masafumi Ito, 2018, Scientific Reports.

Pathophysiological changes of the lower urinary tract behind voiding dysfunction in streptozotocin-induced long-term diabetic rats

H. Kume, Kazuki Masuda, T. Okegawa, 2020, Scientific Reports.

Characteristics of the mechanosensitive bladder afferent activities in relation with microcontractions in male rats with bladder outlet obstruction

Y. Homma, H. Fukuhara, K. Andersson, 2017, Scientific Reports.

Influence of High Fat Diet Feeding for 20 Weeks on Lower Urinary Tract Function in Mice

Y. Homma, Y. Igawa, Naoki Aizawa, 2013, Lower urinary tract symptoms.

Inhibitory effects of vibegron, a β3-adrenoceptor agonist, on the myogenic contractile and mechanosensitive afferent activities in an obstructed rat bladder.

T. Fujita, Naoki Aizawa, 2022, European journal of pharmacology.

Incontinence: How do β3-adrenoceptor agonists work in the bladder?

Y. Igawa, Naoki Aizawa, 2017, Nature Reviews Urology.

Effects of intravesical instillation of ATP on rat bladder primary afferent activity and its relationship with capsaicin‐sensitivity

J. Wyndaele, K. Andersson, Y. Igawa, 2011, Neurourology and urodynamics.

Changes in the function and expression of T-type and N-type calcium channels in the rat bladder after bladder outlet obstruction.

H. Nishimatsu, Y. Homma, N. Takahashi, 2014, Journal of Urology.

Longitudinal change of comprehensive lower urinary tract symptoms and various types of urinary incontinence during robot‐assisted radical prostatectomy

T. Sugihara, H. Kume, Y. Homma, 2019, Neurourology and urodynamics.

Efficacy of the combination of KPR-5714, a novel transient receptor potential melastatin 8 (TRPM8) antagonist, and β3-adrenoceptor agonist or anticholinergic agent on bladder dysfunction in rats with bladder overactivity.

T. Fujita, O. Nakanishi, Yoshikazu Fujimori, 2021, European journal of pharmacology.

Inhibitory effects of retigabine, a Kv7 channel activator, on mechanosensitive primary bladder afferent activities and nociceptive behaviors in rats

Y. Homma, Y. Igawa, Naoki Aizawa, 2017, Neurourology and urodynamics.

Functional roles of bladder α1‐adrenoceptors in the activation of single‐unit primary bladder afferent activity in rats

Y. Homma, H. Fukuhara, Y. Igawa, 2016, BJU international.

Influence of urethane‐anesthesia on the effect of resiniferatoxin treatment on bladder function in rats with spinal cord injury

Y. Homma, Y. Igawa, Naoki Aizawa, 2015, Neurourology and urodynamics.

LONG-TERM CALORIE RESTRICTION PROTECTS AGAINST AGE-RELATED OXIDATIVE AND FIBROTIC CHANGES IN THE RAT BLADDER

Y. Homma, T. Kojima, Y. Kubota, 2014 .

Differentiation of smooth muscle cells from human amniotic mesenchymal cells implanted in the freeze-injured mouse urinary bladder.

Y. Igawa, Tetsuya Imamura, O. Nishizawa, 2010, European urology.

Near‐Infrared Spectroscopy Detects Prefrontal Activities During Rorschach Inkblot Method

C. Uchiumi, Masahiro Iwakiri, Naoki Aizawa, 2018 .

TRANSIENT RECEPTOR POTENTIAL MELASTATIN 2 (TRPM2) MEDIATES LIPOPOLYSACCHARIDE (LPS)-INDUCED INFRAMMATORY BLADDER PAIN AND FREQUENT VOIDING IN MICE

Y. Homma, T. Nakagawa, S. Kaneko, 2016 .

IN VIVO AND IN VITRO FUNCTIONAL CHARACTERISTICS OF THE BLADDER IN MICE LACKING TRANSIENT RECEPTOR POTENTIAL MELASTATIN 2 (TRPM2) CHANNEL

Y. Homma, T. Nakagawa, S. Kaneko, 2014 .