Hirofumi Yamamoto

发表

Vizantin inhibits bacterial adhesion without affecting bacterial growth and causes Streptococcus mutans biofilm to detach by altering its internal architecture.

M. Oda, S. Takenaka, H. Ohshima, 2016, Biochemical and biophysical research communications.

Growth of diamond films on grooved Si substrates

Y. Shintani, Y. Naoi, Hirofumi Yamamoto, 2002 .

A Nationwide Survey of Anastomotic Leakage in Rectal Cancer Surgery in Japan (Results of a Questionnaire Survey by the 35th Meeting of the Japan Colorectal Surgical Club)

Y. Akagi, M. Yasuno, M. Inomata, 2012 .

Sulfated vizantin suppresses mucin layer penetration dependent on the flagella motility of Pseudomonas aeruginosa PAO1

M. Oda, T. Nakano, Hirofumi Yamamoto, 2018, PloS one.

Discovery of quinazolinone and quinoxaline derivatives as potent and selective poly(ADP‐ribose) polymerase‐1/2 inhibitors

A. Iwashita, T. Kinoshita, N. Matsuoka, 2005, FEBS letters.

Carbonate Apatite Nanoparticles Act as Potent Vaccine Adjuvant Delivery Vehicles by Enhancing Cytokine Production Induced by Encapsulated Cytosine-Phosphate-Guanine Oligodeoxynucleotides

K. Ishii, Y. Yoshioka, T. Aoshi, 2018, Front. Immunol..

Sulfated vizantin induces formation of macrophage extracellular traps

Mie Kurosawa, M. Oda, T. Maekawa, 2018, Microbiology and immunology.

A heterogeneous mercury salt catalyst stabilized by m-carbaborane

T. Kawakami, H. Imagawa, Y. Kasai, 2015 .

Vizantin Inhibits Endotoxin-Mediated Immune Responses via the TLR 4/MD-2 Complex

Mie Kurosawa, M. Nagahama, M. Oda, 2014, The Journal of Immunology.

Sulfated vizantin causes detachment of biofilms composed mainly of the genus Streptococcus without affecting bacterial growth and viability

M. Oda, S. Takenaka, H. Ohshima, 2020, BMC microbiology.

A new catalyst for organic synthesis: mercuric triflate.

H. Imagawa, M. Nishizawa, Hirofumi Yamamoto, 2010, Organic & biomolecular chemistry.

Silaphenylmercuric triflate catalyzed reactions: synthesis of a solid-supported mercuric salt catalyst.

H. Imagawa, M. Nishizawa, K. Namba, 2009, Angewandte Chemie.

Aryl-Allene Cyclization via a Hg(OTf)2-Catalytic Pathway.

Kazunobu Igawa, H. Imagawa, M. Nishizawa, 2016, Organic letters.

Yellow Pigments, Fomitellanols A and B, and Drimane Sesquiterpenoids, Cryptoporic Acids P and Q, from Fomitella fraxinea and Their Inhibitory Activity against COX and 5-LO

H. Imagawa, S. Arihara, K. Yoshikawa, 2013, Molecules.

Hg(OTf)2-catalyzed glycosylation using alkynoate as the leaving group

H. Imagawa, M. Nishizawa, Hirofumi Yamamoto, 2006 .

Discovery of potent and selective PARP-1 and PARP-2 inhibitors: SBDD analysis via a combination of X-ray structural study and homology modeling.

A. Iwashita, T. Kinoshita, N. Matsuoka, 2006, Bioorganic & medicinal chemistry.

Formation of heterocycles by the Mitsunobu reaction. Stereoselective synthesis of (+)-α-skytanthine

Hirofumi Yamamoto, S. Ito, T. Tsunoda, 1996 .

Orally Active Cephalosporins. Part 4. Synthesis, Structure—Activity Relationships and Oral Absorption of Novel 3‐(4‐Pyrazolylmethylthio)cephalosporins with Various C‐7 Side Chains.

Y. Matsumoto, S. Matsumoto, Hirofumi Yamamoto, 2002 .

Neuroprotective Effects of a Novel Poly(ADP-Ribose) Polymerase-1 Inhibitor, 2-{3-[4-(4-Chlorophenyl)-1-piperazinyl] propyl}-4(3H)-quinazolinone (FR255595), in an in Vitro Model of Cell Death and in Mouse 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine Model of Parkinson's Disease

A. Iwashita, N. Matsuoka, K. Hattori, 2004, Journal of Pharmacology and Experimental Therapeutics.

Hg(OTf)2-BINAPHANE-catalyzed enantioselective anilino sulfonamide allyl alcohol cyclization.

H. Imagawa, M. Nishizawa, K. Namba, 2010, Chemistry.

Hg(OTf)2-Catalyzed cyclization of alkynyl tert-butylcarbonate leading to cyclic enol carbonate

H. Imagawa, M. Nishizawa, Hirofumi Yamamoto, 2006 .

Orally active cephalosporins. Part 4: synthesis, structure--activity relationships and oral absorption of novel 3-(4-pyrazolylmethylthio)cephalosporins with various C-7 side chains.

Hirokazu Tanaka, Y. Matsumoto, S. Matsumoto, 2002, Bioorganic & medicinal chemistry.

Asymmetric synthesis of anthracyclinones : synthesis of a new chiral AB-synthon, (5R,6R)-6-ethyl-5,6-dihydroxy-5,6,7,8-tetrahydro-1,4-naphthoquinone, and its application for a novel regioselective synthesis of (-)-γ-rhodomycinone

Y. Kita, H. Annoura, H. Fujioka, 1992 .

Hg(OTf)2-catalyzed arylene cyclization.

H. Imagawa, M. Nishizawa, K. Namba, 2008, Organic letters.

Hg(OTf)2-Catalyzed cycloisomerization of 2-ethynylaniline derivatives leading to indoles

H. Imagawa, M. Nishizawa, Hirofumi Yamamoto, 2007 .

4-Phenyl-1,2,3,6-tetrahydropyridine, an excellent fragment to improve the potency of PARP-1 inhibitors.

A. Iwashita, N. Matsuoka, K. Hattori, 2005, Bioorganic & medicinal chemistry letters.

Syntheses of thallusin analogues and their algal morphogenesis-inducing activities

H. Imagawa, Y. Kasai, Yuichi Takagi, 2018, Tetrahedron.

Total synthesis of (-)-thallusin: utilization of enzymatic hydrolysis resolution.

Y. Matsuo, H. Imagawa, H. Kenmoku, 2014, The Journal of organic chemistry.

Rational approaches to discovery of orally active and brain-penetrable quinazolinone inhibitors of poly(ADP-ribose)polymerase.

Takayoshi Kinoshita, Kenji Murano, Yoshiyuki Kido, 2004, Journal of medicinal chemistry.

Rational design of conformationally restricted quinazolinone inhibitors of poly(ADP-ribose)polymerase.

A. Iwashita, K. Hattori, Junya Ishida, 2007, Bioorganic & medicinal chemistry letters.

Toward palau'amine: Hg(OTf)2-catalyzed synthesis of the cyclopentane core.

Robert M. Williams, H. Imagawa, M. Nishizawa, 2009, Chemistry.

Hg(OTf)2-CatalyzedInstantaneous Hydration of β- and δ-Hydroxy Internal Alkyneswith Complete Regioselectivity

H. Imagawa, M. Nishizawa, K. Namba, 2009 .

Asymmetric Synthesis Using Chiral Acetals : Highly Diastereoselective Nucleophilic Addition of Grignard Reagents to Chiral 1-Oxo-β-tetralone 1-Acetals

Y. Kita, H. Annoura, H. Fujioka, 1989 .

Asymmetric synthesis of anthracyclinones using chiral acetal: synthesis of a new chiral AB-synthon, ()-2-bromo-6-ethynyl-6-hydroxy-5, 6, 7, 8-tetrahydro-1, 4-naphthoquinone, and its application for ()-7-deoxydaunomycinone

Y. Kita, H. Annoura, H. Fujioka, 1987 .

Hg(OAc)(2).0.1Sc(OTf)(3)-catalyzed cycloisomerization of 2-(4-pentynyl)furan.

H. Imagawa, M. Nishizawa, Hirofumi Yamamoto, 2007, Organic letters.

Virtually Complete E-Selective α,β-Unsaturated Ester Synthesis by Hg(OTf)2-Catalyzed Hydration of sec-Ethoxyalkynyl Acetate

H. Imagawa, M. Nishizawa, K. Namba, 2007 .

Catalytic activation of the leaving group in the S(N)2 reaction.

H. Imagawa, M. Nishizawa, K. Namba, 2007, Organic letters.

Mitsunobu-type alkylation of p-toluenesulfonamide. A convenient new route to primary and secondary amines

Hirofumi Yamamoto, S. Ito, T. Tsunoda, 1996 .

A carbaboranylmercuric salt catalyzed reaction; highly regioselective cycloisomerization of 1,3-dienes.

H. Imagawa, Hirofumi Yamamoto, Ikuo Sasaki, 2012, Organic letters.

Hg(OTf)2-catalyzed Cycloisomerization of Aryl- and Hetero-substituted 1,3-Dienes

H. Imagawa, M. Nishizawa, K. Namba, 2010 .

Total synthesis and morphogenesis-inducing activity of (±)-thallusin and its analogues

Mohammed Sharfuddin, Y. Matsuo, H. Imagawa, 2007 .

Triethyl- (or trimethyl-)silyl triflate-catalyzed reductive cleavage of triphenylmethyl (trityl) ethers with triethylsilane.

R. Singh, H. Imagawa, M. Nishizawa, 2003, Organic letters.

Hg(OTf)2-Catalyzed Cyclization of N-Tosylanilinoallylic Alcohols to 2-Vinylindolines

H. Imagawa, M. Nishizawa, K. Namba, 2008 .

Hg(OTf)2-catalyzed arylene cyclization.

H. Imagawa, M. Nishizawa, K. Namba, 2008, Organic letters.

Intermolecular Amination of Allyl Alcohols with Sulfamates: Effective Utilization of Mercuric Catalyst

H. Imagawa, M. Nishizawa, Yuichi Takagi, 2011 .

TMS triflate-catalyzed cleavage of prenyl (3-methylbut-2-enyl) ester.

H. Imagawa, M. Nishizawa, T. Sugihara, 2002, Organic letters.

The photolysis of N,O-diacyl-N-phenylhydroxylamines

T. Sakurai, H. Inoue, S. Yamada, 1983 .

The photolysis of N,O-diacyl-N-phenylhydroxylamines

T. Sakurai, H. Inoue, S. Yamada, 1985 .

Alkylamides from pericarps of Zanthoxylum bungeanum

Q. Xiong, M. Mizuno, Hirofumi Yamamoto, 1997 .

Effects of Moranoline, 4-O-α-D-Glucopyranosylmoranoline and Their N-Substituted Derivatives on Thermostability of Cyclodextrin Glycosyltransferase, Glucoamylase, and β-Amylase

Hirofumi Yamamoto, Y. Ezure, Y. Kyotani, 1993 .

A synthetic protocol for (−)-ketorolac; development of asymmetric gold(I)-catalyzed cyclization of allyl alcohol with pyrrole ring core

H. Imagawa, Y. Kasai, Hirofumi Yamamoto, 2020 .

Sulfated vizantin inhibits biofilm maturation by Streptococcus mutans

Mie Kurosawa, M. Oda, S. Takenaka, 2020, Microbiology and immunology.

Total synthesis of (+/-)-neovibsanin B.

Y. Fukuyama, H. Imagawa, M. Nishizawa, 2009, Organic letters.

Novel bicyclic pyrazoles as potent ALK2 (R206H) inhibitors for the treatment of fibrodysplasia ossificans progressiva.

K. Miyazono, M. Shirouzu, T. Honma, 2021, Bioorganic & medicinal chemistry letters.

Development of vizantin, a safe immunostimulant, based on the structure-activity relationship of trehalose-6,6'-dicorynomycolate.

M. Nagahama, M. Oda, Naoyuki Watanabe, 2013, Journal of medicinal chemistry.

The first total synthesis of a potent β-rhodonycin, oxaunonycin: regioselectiveglycosidation of the c-7 hydroxyl c-7 group of β-rhodomycinone

Y. Kita, H. Fujioka, H. Maeda, 1990 .

A New Poly(ADP-Ribose) Polymerase Inhibitor, FR261529 [2-(4-Chlorophenyl)-5-quinoxalinecarboxamide], Ameliorates Methamphetamine-Induced Dopaminergic Neurotoxicity in Mice

A. Iwashita, N. Matsuoka, K. Hattori, 2004, Journal of Pharmacology and Experimental Therapeutics.

A Novel and Potent Poly(ADP-Ribose) Polymerase-1 Inhibitor, FR247304 (5-Chloro-2-[3-(4-phenyl-3,6-dihydro-1(2H)-pyridinyl)propyl]-4(3H)-quinazolinone), Attenuates Neuronal Damage in in Vitro and in Vivo Models of Cerebral Ischemia

A. Iwashita, N. Matsuoka, K. Hattori, 2004, Journal of Pharmacology and Experimental Therapeutics.

Syntheses of structurally-simplified and fluorescently-labeled neovibsanin derivatives and analysis of their neurite outgrowth activity in PC12 cells.

M. Nagahama, M. Oda, Y. Fukuyama, 2012, Bioorganic & medicinal chemistry letters.

Total synthesis of (±)-spirotenuipesine A, a promoter of neurotrophic factor secretion from glial cells

Y. Fukuyama, H. Imagawa, Y. Kasai, 2020 .

Efficient syntheses of a series of trehalose dimycolate (TDM)/trehalose dicorynomycolate (TDCM) analogues and their interleukin-6 level enhancement activity in mice sera.

I. Azuma, D. Papy-Garcia, H. Imagawa, 2007, The Journal of organic chemistry.

A glucose carbonate apatite complex exhibits in vitro and in vivo anti-tumour effects

Y. Doki, M. Mori, I. Takemasa, 2015, Scientific Reports.

m-C2B10H11HgCl/AgOTf-Catalyzed Reaction for Reductive Deoxygenation

H. Imagawa, Y. Kasai, Hirofumi Yamamoto, 2017, Synlett.

Vizantin Inhibits Endotoxin-Mediated Immune Responses via the TLR 4/MD-2 Complex

Mie Kurosawa, M. Nagahama, M. Oda, 2014, The Journal of Immunology.

Novel inhibitor of bacterial sphingomyelinase, SMY-540, developed based on three-dimensional structure analysis

M. Nagahama, M. Oda, H. Imagawa, 2014, Journal of enzyme inhibition and medicinal chemistry.

Synthesis and evaluation of novel phosphate ester analogs as neutral sphingomyelinase inhibitors.

M. Nagahama, M. Oda, H. Imagawa, 2010, Bioorganic & medicinal chemistry letters.

Regio- and stereo-selective construction of anthracyclinones: total synthesis of (–)-γ-rhodomycinone

Y. Kita, H. Annoura, H. Fujioka, 1989 .

A carbaboranylmercuric salt catalyzed reaction; highly regioselective cycloisomerization of 1,3-dienes.

H. Imagawa, Hirofumi Yamamoto, Ikuo Sasaki, 2012, Organic letters.