D. Graves

发表

Use of a photoactive derivative of actinomycin to investigate shuffling between binding sites on DNA.

M. Waring, C. Bailly, C Bailly, 1994, Biochemistry.

Covalent interactions of ethidium and actinomycin D with nucleic acids

D. Graves, 1996 .

Synthesis, separation and characterization of the mono- and diazide analogs of ethidium bromide.

K. L. Yielding, D. Graves, L. Yielding, 1977, Biochimica et biophysica acta.

Ethidium bromide and its photoreactive analogues: spectroscopic analysis of deoxyribonucleic acid binding properties.

D. Graves, L. Yielding, C. Watkins, 1981, Biochemistry.

7-Azidoactinomycin D: a novel probe for examining actinomycin D-DNA interactions.

R. M. Wadkins, D. Graves, 1989, The Journal of biological chemistry.

Influence of the amino substituents in the interaction of ethidium bromide with DNA.

N. Garbett, Nicholas B. Hammond, D. Graves, 2004, Biophysical journal.

Chemical cross-linking of ethidium to DNA by glyoxal.

J. Chaires, F. Leng, D. Graves, 1998, Biochimica et biophysica acta.

Crystal structure of ethidium monoazide, a photoactive compound that reacts with nucleic acids

C. Bugg, D. Graves, L. Yielding, 1978 .

An unusual oxidation of a benzylic methylene group by thionyl chloride: a synthesis of 1,3-dihydro-2-[2-(dimethyl-amino)ethyl]-1,3-dioxopyrrolo[3,4-c]acridine derivatives.

D. Graves, C. A. Panetta, S. Feng, 2001, The Journal of organic chemistry.

Toll-Like Receptor 9 Mediates CpG Oligonucleotide–Induced Cellular Invasion

A. Jukkola-Vuorinen, K. Vuopala, J. Ilvesaro, 2008, Molecular Cancer Research.

Low TLR9 expression defines an aggressive subtype of triple-negative breast cancer

A. Jukkola-Vuorinen, Y. Soini, P. Karihtala, 2012, Breast Cancer Research and Treatment.

Extending nature's leads: the anticancer agent ellipticine.

N. Garbett, D. Graves, 2004, Current medicinal chemistry. Anti-cancer agents.

Telomeric G-quadruplex-forming DNA fragments induce TLR9-mediated and LL-37-regulated invasion in breast cancer cells in vitro

A. Jukkola-Vuorinen, P. Lehenkari, K. Haapasaari, 2016, Breast Cancer Research and Treatment.

Hypoxia regulates Toll-like receptor-9 expression and invasive function in human brain cancer cells in vitro

K. Selander, J. Tuomela, K. Harris, 2014, Oncology letters.

DNA topoisomerases as targets for the anticancer drug TAS-103: DNA interactions and topoisomerase catalytic inhibition.

N. Osheroff, Yuji Yamada, J. Fortune, 1999, Biochemistry.

Covalent attachment of ethidium to DNA results in enhanced topoisomerase II-mediated DNA cleavage.

N. Osheroff, H. Zhou, G. Marx, 1997, Biochemistry.

Addition of Bases to the 5'-end of Human Telomeric DNA: Influences on Thermal Stability and Energetics of Unfolding

D. Graves, Katherine L. Hayden, 2014, Molecules.

Short DNA sequences and bacterial DNA induce esophageal, gastric, and colorectal cancer cell invasion

T. Salo, P. Lehenkari, P. Nyberg, 2013, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

Interactions of actinomycin D with human telomeric G-quadruplex DNA.

Jason S. Hudson, D. Graves, Sonja C Brooks, 2009, Biochemistry.

Amsacrine as a topoisomerase II poison: importance of drug-DNA interactions.

N. Osheroff, W. Denny, D. Graves, 2012, Biochemistry.

Interactions between the etoposide derivative F14512 and human type II topoisomerases: implications for the C4 spermine moiety in promoting enzyme-mediated DNA cleavage.

N. Osheroff, C. Bailly, M. Jablonský, 2011, Biochemistry.

Structure-activity studies of amsacrine analogs in drug resistant human leukemia cell lines expressing either altered DNA topoisomerase II or P-glycoprotein.

W. T. Beck, M. Danks, B. Baguley, 1992, Oncology research.

Comparative studies of the binding of ethidium bromide and its photoreactive analogues to nucleic acids by fluorescence and rapid kinetics.

H. Cheung, D. Graves, L. Yielding, 1980, Biochemistry.

Thermodynamic Studies of Amsacrine Antitumor Agents with Nucleic Acids

R. M. Wadkins, D. Graves, 1990 .

Calories from carbohydrates: energetic contribution of the carbohydrate moiety of rebeccamycin to DNA binding and the effect of its orientation on topoisomerase I inhibition.

C. Bailly, J. Chaires, M. Prudhomme, 1999, Chemistry & biology.

Drug-DNA interactions.

D. Graves, 2001, Methods in molecular biology.

Targeting DNA through-covalent interactions of reversible binding drugs.

D. Graves, 2001, Methods in enzymology.

Influence of substituent modifications on DNA binding energetics of acridine-based anticancer agents.

W. Denny, D. Graves, J. Crenshaw, 2003, Biochemistry.

Drug interactions with Bacillus anthracis topoisomerase IV: biochemical basis for quinolone action and resistance.

N. Osheroff, C. Turnbough, R. Kerns, 2012, Biochemistry.

Synthesis of the ABC ring system of Azaspiracid. 2. A systematic study into the effect of C(16) and C(17) substitution on bis-spirocyclization.

Gregory S. Tschumper, R. Carter, D. Graves, 2002, Organic letters.

Synthesis of the ABC ring system of azaspiracid. 1. Effect of D ring truncation on bis-spirocyclization.

R. Carter, D. Graves, T. Bourland, 2002, Organic letters.

Studies directed toward the total synthesis of azaspiracid. Construction of the C1–C19 carbon backbone and synthesis of the C10, C13 nonnatural transoidal bisspirocyclic ring system

R. Carter, D. Graves, 2001 .

Antiviral and Anticancer Optimization Studies of the DNA‐binding Marine Natural Product Aaptamine

R. Schinazi, S. Wahyuono, F. Valeriote, 2008, Chemical biology & drug design.

Two-dimensional NMR studies on the anthramycin-d(ATGCAT)2 adduct.

T. Krugh, M. Stone, D. Graves, 1989, Biochemistry.

Structure of the anthramycin-d(ATGCAT)2 adduct from one- and two-dimensional proton NMR experiments in solution.

T. Krugh, M. Stone, D. Graves, 1985, Biochemistry.

The reaction of anthramycin with DNA. Proton and carbon nuclear magnetic resonance studies on the structure of the anthramycin-DNA adduct.

T. Krugh, L. Hurley, D. Graves, 1984, The Journal of biological chemistry.

Substituents on etoposide that interact with human topoisomerase IIalpha in the binary enzyme-drug complex: contributions to etoposide binding and activity.

N. Osheroff, C. Anklin, R. Bender, 2008, Biochemistry.

Recognition and Binding of Human Telomeric G-Quadruplex DNA by Unfolding Protein 1

E. Lewis, V. Le, Jason S. Hudson, 2014, Biochemistry.

Interactions of anilinoacridines with nucleic acids: effects of substituent modifications on DNA-binding properties.

R. M. Wadkins, R M Wadkins, D E Graves, 1991, Biochemistry.

Topoisomerase II - drug interaction domains: identification of substituents on etoposide that interact with the enzyme.

N. Osheroff, C. Anklin, R. Bender, 2007, Biochemistry.

Binding of actinomycin D to the T(G)nT motif of double-stranded DNA: determination of the guanine requirement in nonclassical, non-GpC binding sites.

R. Rill, D. Graves, S. Bailey, 1994, Biochemistry.

Inhibition of the B to Z transition in poly(dGdC).poly(dGdC) by covalent attachment of ethidium: kinetic studies.

J. Chaires, D. Graves, M. Britt, 1991, Biochemistry.

Covalent binding of ethidium azide analogs to Salmonella DNA in vivo: competition by ethidium bromide.

K. L. Yielding, D. Graves, L. Yielding, 1979, Biochemical and biophysical research communications.

Cooperative binding of m-AMSA to nucleic acids.

R. M. Wadkins, D. Graves, R. Elmore, 1988, Nucleic acids research.

Adriamycin and daunorubicin bind in a cooperative manner to deoxyribonucleic acid.

T. Krugh, D. Graves, 1983, Biochemistry.

Photoaffinity approaches to determining the sequence selectivities of DNA-small molecule interactions: actinomycin D and ethidium.

R. Rill, D. Graves, G. Marsch, 1995, Nucleic acids research.

7-Azido-actinomycin D: a photoaffinity probe of the sequence specificity of DNA binding by actinomycin D.

R. Rill, D. Graves, G. Marsch, 1989, Journal of biomolecular structure & dynamics.

Contributions of the D-Ring to the activity of etoposide against human topoisomerase IIα: potential interactions with DNA in the ternary enzyme--drug--DNA complex.

N. Osheroff, C. Anklin, C. Monneret, 2011, Biochemistry.

Stability of the Na+ Form of the Human Telomeric G-Quadruplex: Role of Adenines in Stabilizing G-Quadruplex Structure

R. Sheardy, E. Lewis, E. Kharlampieva, 2018, ACS omega.

DNA from dead cancer cells induces TLR9-mediated invasion and inflammation in living cancer cells

M. Kaakinen, Dongquan Chen, J. Ilvesaro, 2013, Breast Cancer Research and Treatment.

Cembrene A and a congeneric ketone isolated from the paracloacal glands of the Chinese alligator (Alligator sinensis).

P. Weldon, D. Mattern, D. Graves, 1997, Journal of natural products.

Synthesis and characterization of ethidium analogs: Emphasis on amino and azido substituents: Synthesis and Characterization of Ethidium Analogs

D. Graves, L. Yielding, C. Watkins, 1983 .

Synthesis and characterization of ethidium analogs: Emphasis on amino and azido substituents

D. Graves, C. Watkins, W. Firth, 1983 .

Ethidium bromide enhancement of frameshift mutagenesis caused by photoactivatable ethidium analogs.

K. L. Yielding, D. Graves, L. Yielding, 1979, Mutation research.

Single-cell partition analysis--a direct fluorescence technique for examining ligand-macromolecule interactions.

T. Krugh, D. Graves, 1983, Analytical biochemistry.

Encapsulation and Ultrasound-Triggered Release of G-Quadruplex DNA in Multilayer Hydrogel Microcapsules

V. Kozlovskaya, E. Kharlampieva, N. Gupta, 2018, Polymers.

Influence of DNA base sequence on the binding energetics of actinomycin D.

R. Rill, D. Graves, G. Marsch, 1993, Biochemistry.

Carcinogen-nucleic acid interactions: equilibrium binding studies of aflatoxins B1 and B2 with DNA and the oligodeoxynucleotide d(ATGCAT)2.

T. Harris, M. Stone, S. Gopalakrishnan, 1988, Journal of biomolecular structure & dynamics.

Encapsulation and Ultrasound-Triggered Release of G-Quadruplex DNA in Multilayer Hydrogel Microcapsules

V. Kozlovskaya, E. Kharlampieva, Jun Chen, 2018, Polymers.

Interactions between the etoposide derivative F14512 and human type II topoisomerases: implications for the C4 spermine moiety in promoting enzyme-mediated DNA cleavage.

N. Osheroff, C. Bailly, M. Jablonský, 2011, Biochemistry.