F. Kockar

发表

Mutation of Phe91 to Asn in human carbonic anhydrase I unexpectedly enhanced both catalytic activity and affinity for sulfonamide inhibitors.

C. Supuran, A. Maresca, S. Sinan, 2010, Bioorganic & medicinal chemistry.

Interleukin-6 represses the transcription of the CCAAT/enhancer binding protein-alpha gene in hepatoma cells by inhibiting its ability to autoactivate the proximal promoter region.

D. Ramji, S. Irvine, P. Foka, 2003, Nucleic acids research.

Identification of intracellular pathways through which TGF-β1 upregulates URG-4/URGCP gene expression in hepatoma cells.

F. Kockar, E. Tokay, 2016, Life sciences.

Carbonic anhydrase III is a new target of HIF1α in prostate cancer model.

F. Kockar, Derya Okuyan, Sumeyye Aydogan Turkoglu, 2020, Gene.

The role of hypoxia response element in TGFβ-induced carbonic anhydrase IX expression in Hep3B human hepatoma cells

H. Yıldırım, F. Kockar, M. Karaman, 2017 .

Mutation of active site residues Asn67 to Ile, Gln92 to Val and Leu204 to Ser in human carbonic anhydrase II: influences on the catalytic activity and affinity for inhibitors.

C. Supuran, A. Maresca, S. Sinan, 2012, Bioorganic & medicinal chemistry.

Hypoxia and cytokines regulate carbonic anhydrase 9 expression in hepatocellular carcinoma cells in vitro.

M. Flentje, D. Vordermark, H. Said, 2012, World journal of clinical oncology.

Amphenicol and macrolide derived antibiotics inhibit paraoxonase enzyme activity in human serum and human hepatoma cells (HepG2) in vitro

H. Yıldırım, S. Sinan, N. Gençer, 2006, Biochemistry (Moscow).

TGF-β downregulates CAIII expression via MAPK and PI3K signaling pathways in colon carcinoma and osteosarcoma cells

F. Kockar, S. Turkoglu, Derya Okuyan, 2019, Archives of Biological Sciences.

IL-6 upregulates a disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAMTS-2) in human osteosarcoma cells mediated by JNK pathway

F. Kockar, M. Alper, 2014, Molecular and Cellular Biochemistry.

SP1-mediated downregulation of ADAMTS3 gene expression in osteosarcoma models.

F. Kockar, M. Alper, A. Aydemir, 2018, Gene.

SP1 and USF differentially regulate ADAMTS1 gene expression under normoxic and hypoxic conditions in hepatoma cells.

F. Kockar, S. Turkoglu, S. Turkoğlu, 2016, Gene.

Differential effects of some antibiotics on paraoxonase enzyme activity on human hepatoma cells (HepG2) in vitro

H. Yıldırım, S. Sinan, O. Arslan, 2010, Journal of enzyme inhibition and medicinal chemistry.

hCAIX Expression and Cell Cycle in Cytokine Stimulated Human Colon Cancer Cells

S. Yılmaz, U. Muşabak, F. Kockar, 2019 .

Characterisation and developmental regulation of the Xenopus laevis CCAAT-enhancer binding protein β gene

D. Ramji, S. Kousteni, F. Kockar, 1998, Mechanisms of Development.

Molecular characterization of zeta class glutathione S-transferases from Pinus brutia Ten.

M. Işcan, M. Alper, E. Oztetik, 2015, Journal of Genetics.

Novel debittering process of green table olives: application of β-glucosidase bound onto superparamagnetic nanoparticles

O. Karaagac, H. Kockar, F. Kockar, 2018 .

Molecular characterization of zeta class glutathione S-transferases from Pinus brutia Ten.

M. Işcan, M. Alper, E. Oztetik, 2015, Journal of Genetics.

Evaluation of the effects of dexketoprofen trometamol on knee joınt: an in vivo & in vitro study

H. Yıldırım, F. Sunay, A. Koroglu, 2013, The Indian journal of medical research.

Investigations of Genetic Variation Between Olive (Olea europaea L.) Cultivars Using Arbitrarily Primed Polymerase Chain Reaction (AP-PCR)

Rahşan Ilıkçı, F. Kockar, 2003, Zeitschrift fur Naturforschung. C, Journal of biosciences.

Novel purification strategy for human PON1 and inhibition of the activity by cephalosporin and aminoglikozide derived antibiotics.

S. Sinan, Oktay Arslan, Selma Sinan, 2006, Biochimie.

Effects of some antibiotics on paraoxonase from human serum in vitro and from mouse serum and liver in vivo.

H. Yıldırım, S. Sinan, N. Gençer, 2006, Biological & pharmaceutical bulletin.

Evaluation of Azadirachtin onArthrospira plantensisGomont growth parameters and antioxidant enzymes

F. Kockar, Ali Doğru, H. Tunca, 2020, Annales de Limnologie - International Journal of Limnology.

Investigation of antioxidant, enzyme inhibition and antiproliferative activities of blackthorn (Prunus spinosa L.) extracts

F. Köçkar, M. Ay, F. Kockar, 2021, International Journal of Life Sciences and Biotechnology.

Differential in vitro inhibition effects of some antibiotics on tumor associated carbonic anhydrase isozymes of hCA-IX and hCA-XII

O. Arslan, F. Kockar, O. Ozensoy, 2008 .

Analysis of the Xenopus laevis CCAAT-enhancer binding protein alpha gene promoter demonstrates species-specific differences in the mechanisms for both auto-activation and regulation by Sp1.

T. Hughes, D. Ramji, S. Kousteni, 2001, Nucleic acids research.

Cloning, characterization and anion inhibition study of a β-class carbonic anhydrase from the caries producing pathogen Streptococcus mutans.

C. Supuran, V. De Luca, C. Capasso, 2015, Bioorganic & medicinal chemistry.

Sulfonamide inhibition study of the β-class carbonic anhydrase from the caries producing pathogen Streptococcus mutans.

C. Supuran, C. Capasso, H. Yıldırım, 2015, Bioorganic & medicinal chemistry letters.

Carbonic anhydrase inhibitors: inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates.

C. Supuran, A. Scozzafava, A. Innocenti, 2009, Bioorganic & medicinal chemistry.

Saccharomyces cerevisiae β-carbonic anhydrase: inhibition and activation studies.

C. Supuran, O. O. Guler, O. Arslan, 2010, Current pharmaceutical design.

Carbonic anhydrase inhibitors. Inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with anions.

C. Supuran, A. Innocenti, O. O. Guler, 2008, Bioorganic & medicinal chemistry letters.

Amplification of GC-rich ADAMTS-2 and URG4/URGCP promoter regions with optimized combination of PCR enhancers

F. Kockar, E. Tokay, M. Alper, 2016 .

Antidepressant and antipsychotic drugs differentially affect PON1 enzyme activity

S. Sinan, F. Kockar, A. Avcıkurt, 2015, Journal of enzyme inhibition and medicinal chemistry.

IL-6 upregulates a disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAMTS-2) in human osteosarcoma cells mediated by JNK pathway

F. Kockar, M. Alper, 2014, Molecular and Cellular Biochemistry.

Prodrugs for Nitroreductase Based Cancer Therapy- 1: Metabolite Profile, Cell Cytotoxicity and Molecular Modeling Interactions of Nitro Benzamides with Ssap-NtrB.

M. Ay, T. Tok, F. Kockar, 2017, Medicinal chemistry (Shariqah (United Arab Emirates)).

Antiproliferative activity of some novel platinum complexes on C6 glioma and MCF-7 breast cancer cells

H. Yıldırım, Canan Nakiboğlu, F. Kockar, 2012 .

Carbonic anhydrase activators: activation of the beta-carbonic anhydrase Nce103 from the yeast Saccharomyces cerevisiae with amines and amino acids.

C. Supuran, A. Scozzafava, A. Innocenti, 2009, Bioorganic & medicinal chemistry letters.

TNF-α Induces URG-4/URGCP Gene Expression in Hepatoma Cells through Starvation Dependent Manner

F. Kockar, E. Tokay, R. Sagkan, 2020, Biochemical genetics.

TNF-α Induces URG-4/URGCP Gene Expression in Hepatoma Cells through Starvation Dependent Manner

F. Kockar, E. Tokay, R. Sagkan, 2020, Biochemical Genetics.

SP1 is a transcriptional regulator of URG-4/URGCP gene in hepatocytes

F. Kockar, E. Tokay, 2016, Molecular and Cellular Biochemistry.

An evaluation of cytosolic erythrocyte carbonic anhydrase and catalase in carcinoma patients: an elevation of carbonic anhydrase activity.

C. Supuran, M. Lyon, O. Arslan, 2006, Clinical biochemistry.

Mutation of Phe91 to Asn in human carbonic anhydrase I unexpectedly enhanced both catalytic activity and affinity for sulfonamide inhibitors.

C. Supuran, A. Maresca, S. Sinan, 2010, Bioorganic & medicinal chemistry.

Selagibenzophenone B and Its Derivatives: SelB-1, a Dual Topoisomerase I/II Inhibitor Identified through In Vitro and In Silico Analyses

F. Kockar, T. Tumer, E. Tokay, 2024, ACS bio & med chem Au.