S. Wolkenberg

发表

Reducing Limitation in Probe Design: The Development of a Diazirine-Compatible Suzuki-Miyaura Cross Coupling Reaction.

A. Wassermann, S. Krska, Keith P. Moore, 2018, ACS medicinal chemistry letters.

Mechanisms of in situ activation for DNA-targeting antitumor agents.

D. Boger, S. Wolkenberg, 2002, Chemical reviews.

Discovery of MK-1832, a Kv1.5 inhibitor with improved selectivity and pharmacokinetics.

K. K. Nanda, C. Lindsley, R. Spencer, 2017, Bioorganic & medicinal chemistry letters.

Redefining the Histone Deacetylase Inhibitor Pharmacophore: High Potency with No Zinc Cofactor Interaction

P. Coleman, Christopher D. Cox, D. Klein, 2021, ACS medicinal chemistry letters.

Discovery of an Anion-Dependent Farnesyltransferase Inhibitor from a Phenotypic Screen.

Peter S. Kutchukian, A. W. Shaw, Jing Li, 2020, ACS medicinal chemistry letters.

Characterization of non-nitrocatechol pan and isoform specific catechol-O-methyltransferase inhibitors and substrates.

Scott T. Harrison, K. K. Nanda, Monika Kandebo, 2012, ACS chemical neuroscience.

Identification of potent agonists of photoreceptor-specific nuclear receptor (NR2E3) and preparation of a radioligand.

A. Webber, C. Lindsley, D. Dean, 2006, Bioorganic & medicinal chemistry letters.

Direct-to-Biology Accelerates PROTAC Synthesis and the Evaluation of Linker Effects on Permeability and Degradation

Iulia I. Strambeanu, Jennifer D. Venable, C. Chaudhry, 2022, ACS medicinal chemistry letters.

Progress towards validating the NMDA receptor hypofunction hypothesis of schizophrenia.

W. Shipe, Cory R. Theberge, C. Lindsley, 2006, Current topics in medicinal chemistry.

Recent progress in the discovery of non-sarcosine based GlyT1 inhibitors.

C. Sur, S. Wolkenberg, 2010, Current topics in medicinal chemistry.

Design, synthesis, and evaluation of novel 3,6-diaryl-4-aminoalkoxyquinolines as selective agonists of somatostatin receptor subtype 2.

T. Mcdonald, C. Lindsley, C. Thut, 2011, Journal of medicinal chemistry.

Recent advances in positive allosteric modulators of metabotropic glutamate receptors.

W. Shipe, C. Lindsley, David Williams, 2005, Current opinion in drug discovery & development.

Synthesis and SAR of GlyT1 inhibitors derived from a series of N-((4-(morpholine-4-carbonyl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamides.

C. Lindsley, M. Jacobson, G. Hartman, 2006, Bioorganic & medicinal chemistry letters.

Discovery of Highly Selective and Potent HDAC3 Inhibitors Based on a 2-Substituted Benzamide Zinc Binding Group.

D. Klein, M. Holloway, B. Howell, 2020, ACS medicinal chemistry letters.

Discovery of ethyl ketone-based HDACs 1, 2, and 3 selective inhibitors for HIV latency reactivation.

James I. Fells, D. Klein, R. Myers, 2020, Bioorganic & medicinal chemistry letters.

Trends in Hit-to-Lead Optimization Following DNA-Encoded Library Screens.

Nicholas Simmons, S. Wolkenberg, David P. Schuman, 2021, ACS medicinal chemistry letters.

In vitro Characterization of MK-3328: A Novel Fluorinated Positron Emission Tomography Tracer for Plaques

Scott T. Harrison, E. Hostetler, B. Connolly, 2010, Alzheimer's & Dementia.

Discovery of GlyT1 inhibitors with improved pharmacokinetic properties.

B. Ma, C. Lindsley, M. Jacobson, 2009, Bioorganic & medicinal chemistry letters.

General microwave-assisted protocols for the expedient synthesis of quinoxalines and heterocyclic pyrazines

C. Lindsley, D. Wisnoski, Yi Wang, 2004 .

Controlled derivatization of polyhalogenated quinolines utilizing selective cross-coupling reactions

S. Wolkenberg, M. Nolt, Zhijian Zhao, 2008 .

Total synthesis of anhydrolycorinone utilizing sequential intramolecular Diels-Alder reactions of a 1,3,4-oxadiazole.

D. Boger, S. Wolkenberg, 2002, The Journal of organic chemistry.

Efficient synthesis of imidazoles from aldehydes and 1,2-diketones using microwave irradiation.

C. Lindsley, D. Wisnoski, Yi Wang, 2004, Organic letters.

Convenient preparation of substituted 5-aminooxazoles via a microwave-assisted Cornforth rearrangement

C. Lindsley, S. Varga, R. McClain, 2006 .

General Microwave-Assisted Protocols for the Expedient Synthesis of Quinoxalines and Heterocyclic Pyrazines.

C. Lindsley, D. Wisnoski, Yi Wang, 2004 .

Convenient and General Microwave-Assisted Protocols for the Expedient Synthesis of Heterocycles

W. Shipe, C. Lindsley, Feng V Yang, 2006 .

Total synthesis of Amaryllidaceae alkaloids utilizing sequential intramolecular heterocyclic azadiene Diels-Alder reactions of an unsymmetrical 1,2,4,5-tetrazine.

D. Boger, S. Wolkenberg, 2000, The Journal of organic chemistry.

Accelerating lead development by microwave-enhanced medicinal chemistry.

W. Shipe, C. Lindsley, S. Wolkenberg, 2005, Drug discovery today. Technologies.

Mechanisms of in situ Activation for DNA-Targeting Antitumor Agents

D. Boger, S. Wolkenberg, 2002 .

Convenient Preparation of Substituted 5‐Aminooxazoles via a Microwave‐Assisted Cornforth Rearrangement.

C. Lindsley, S. Varga, R. McClain, 2006 .

Applications of microwave-assisted organic synthesis on the multigram scale.

W. Shipe, C. Lindsley, S. Wolkenberg, 2005, Current opinion in drug discovery & development.

Total synthesis of cytostatin

D. Boger, B. Lawhorn, S. B. Boga, 2006 .

Novel indole-3-sulfonamides as potent HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs).

G. McGaughey, Youwei Yan, L. Gabryelski, 2008, Bioorganic & medicinal chemistry letters.

Total synthesis and evaluation of cytostatin, its C10-C11 diastereomers, and additional key analogues: impact on PP2A inhibition.

D. Boger, B. Lawhorn, C. Gauss, 2006, Journal of the American Chemical Society.

DNA alkylation properties of yatakemycin.

D. Boger, Y. Igarashi, David B. Kastrinsky, 2003, Journal of the American Chemical Society.

Rational design, synthesis, and evaluation of key analogues of CC-1065 and the duocarmycins.

D. Boger, A. Zaid, P. Baraldi, 2007, Journal of the American Chemical Society.

Combinatorial Synthesis and Discovery of an Antibiotic Compound. An Experiment Suitable for High School and Undergraduate Laboratories

A. I. Su, S. Wolkenberg, 2001 .

Intramolecular Diels-Alder and tandem intramolecular Diels-Alder/1,3-dipolar cycloaddition reactions of 1,3,4-oxadiazoles.

Gregory I. Elliott, D. Boger, B. Blagg, 2002, Journal of the American Chemical Society.

Intramolecular Diels—Alder and Tandem Intramolecular Diels—Alder/1,3-Dipolar Cycloaddition Reactions of 1,3,4-Oxadiazoles.

D. Boger, B. Blagg, Michael M. Miller, 2003 .

[18F]Fluoroazabenzoxazoles as potential amyloid plaque PET tracers: synthesis and in vivo evaluation in rhesus monkey.

Sandra M. Sanabria-Bohórquez, Scott T. Harrison, E. Hostetler, 2011, Nuclear medicine and biology.

Synthesis and Evaluation of 5-Fluoro-2-aryloxazolo[5,4-b]pyridines as β-Amyloid PET Ligands and Identification of MK-3328.

Sandra M. Sanabria-Bohórquez, Scott T. Harrison, E. Hostetler, 2011, ACS medicinal chemistry letters.

High concentration electrophysiology-based fragment screen: discovery of novel acid-sensing ion channel 3 (ASIC3) inhibitors.

Zhijian Zhao, James C Barrow, Scott T. Harrison, 2011, Bioorganic & medicinal chemistry letters.

Potent antagonists of the Kv1.5 potassium channel: synthesis and evaluation of analogous N,N-diisopropyl-2-(pyridine-3-yl)acetamides.

K. K. Nanda, C. Lindsley, R. Spencer, 2006, Bioorganic & medicinal chemistry letters.

Synthesis and Evaluation of Heterocyclic Catechol Mimics as Inhibitors of Catechol-O-methyltransferase (COMT).

Scott T. Harrison, Sujata Sharma, J. Barrow, 2015, ACS medicinal chemistry letters.

Discovery of N-{[1-(propylsulfonyl)-4-pyridin-2-ylpiperidin-4-yl]methyl}benzamides as novel, selective and potent GlyT1 inhibitors.

C. Lindsley, M. Jacobson, G. Hartman, 2009, Bioorganic & medicinal chemistry letters.

The synthesis and preclinical evaluation in rhesus monkey of [18F]MK‐6577 and [11C]CMPyPB glycine transporter 1 positron emission tomography radiotracers

Sandra M. Sanabria-Bohórquez, Christine Ryan, Kerry Riffel, 2011, Synapse.

Benzoxazolinone aryl sulfonamides as potent, selective Nav1.7 inhibitors with in vivo efficacy in a preclinical pain model.

Michael A Rossi, D. Henze, J. Majercak, 2017, Bioorganic & medicinal chemistry letters.

Rational design, synthesis, and evaluation of key analogues of CC-1065 and the duocarmycins.

D. Boger, A. Zaid, P. Baraldi, 2007, Journal of the American Chemical Society.

Developing and applying ultrasensitive p24 protein immunoassay for HIV latency

D. Hazuda, M. Swanson, D. Graham, 2015 .

Approaches to Eradicate HIV Infection

D. Tellers, Richard J. O. Barnard, S. Wolkenberg, 2016 .

Progress in the preparation and testing of glycine transporter type-1 (GlyT1) inhibitors.

C. Lindsley, G. Kinney, S. Wolkenberg, 2006, Current topics in medicinal chemistry.

Synthesis and optimization of N-heterocyclic pyridinones as catechol-O-methyltransferase (COMT) inhibitors.

Scott T. Harrison, Monika Kandebo, Sean M. Smith, 2016, Bioorganic & medicinal chemistry letters.