Kaapjoo Park

发表

Synthesis and activity of tryptophan sulfonamide derivatives as novel non-hydroxamate TNF-alpha converting enzyme (TACE) inhibitors.

J. Levin, A. Gopalsamy, J. Ellingboe, 2009, Bioorganic & medicinal chemistry.

Design and synthesis of 3,4-dihydro-1H-[1]-benzothieno[2,3-c]pyran and 3,4-dihydro-1H-pyrano[3,4-b]benzofuran derivatives as non-nucleoside inhibitors of HCV NS5B RNA dependent RNA polymerase.

A. Gopalsamy, G. Ciszewski, J. Ellingboe, 2006, Bioorganic & medicinal chemistry letters.

Design and synthesis of 2,3,4,9-tetrahydro-1H-carbazole and 1,2,3,4-tetrahydro-cyclopenta[b]indole derivatives as non-nucleoside inhibitors of hepatitis C virus NS5B RNA-dependent RNA polymerase.

A. Gopalsamy, G. Ciszewski, M. Shi, 2006, Bioorganic & medicinal chemistry letters.

PLAG alleviates cisplatin-induced cachexia in lung cancer implanted mice

Jae Wha Kim, S. Yoon, Kaapjoo Park, 2022, Translational oncology.

Treatment with glucokinase activator, YH-GKA, increases cell proliferation and decreases glucotoxic apoptosis in INS-1 cells.

Youn-Jung Lee, H. Jun, Y. Oh, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Pentadienylnitrobenzyl and Pentadienylnitropiperonyl Photochemically Removable Protecting Groups.

M. Pirrung, Y. R. Lee, Kaapjoo Park, 1999, The Journal of organic chemistry.

Discovery of a novel phenylethyl benzamide glucokinase activator for the treatment of type 2 diabetes mellitus.

T. Han, Byoung Moon Lee, Dong Hoon Lee, 2013, Bioorganic & medicinal chemistry letters.

Signaling Effects of Demethylasterriquinone B1, a Selective Insulin Receptor Modulator

M. Pirrung, N. Webster, Kaapjoo Park, 2003, Chembiochem : a European journal of chemical biology.

The effect of mGlu5 receptor positive allosteric modulators on signaling molecules in brain slices.

F. Liu, K. Marquis, M. Bowlby, 2006, European journal of pharmacology.

Inhibition of the signal transducer and activator of transcription-3 (STAT3) signaling pathway by 4-oxo-1-phenyl-1,4-dihydroquinoline-3-carboxylic acid esters.

J. Gibbons, S. Jelinsky, Jun Xu, 2008, Journal of medicinal chemistry.

Synthesis of 2,5-dihydroxy-3-(indol-3-yl)benzoquinones by acid-catalyzed condensation of indoles with 2,5-dichlorobenzoquinone.

M. Pirrung, Zhitao Li, Liu Deng, 2002, The Journal of organic chemistry.

Total syntheses of demethylasterriquinone B1, an orally active insulin mimetic, and demethylasterriquinone A1.

M. Pirrung, Jin Zhu, Zhitao Li, 2002, The Journal of organic chemistry.

Discovery of pyrano[3,4-b]indoles as potent and selective HCV NS5B polymerase inhibitors.

Boris Feld, A. Gopalsamy, Kitae Lim, 2004, Journal of medicinal chemistry.

Novel benzofuran-3-one indole inhibitors of PI3 kinase-alpha and the mammalian target of rapamycin: hit to lead studies.

N. Brooijmans, Steven C. Kim, L. Feldberg, 2010, Bioorganic & medicinal chemistry letters.

Novel purine and pyrazolo[3,4-d]pyrimidine inhibitors of PI3 kinase-alpha: Hit to lead studies.

N. Brooijmans, Steven C. Kim, L. Feldberg, 2010, Bioorganic & medicinal chemistry letters.

Total Synthesis and Immunosuppressive Activity of (−)-Pateamine A and Related Compounds: Implementation of a β-Lactam-Based Macrocyclization

Jun O. Liu, J. M. Langenhan, R. Rzasa, 1998 .

Isolation and identification of eukaryotic initiation factor 4A as a molecular target for the marine natural product Pateamine A.

Jun O. Liu, Yongjun Dang, N. Choi, 2007, Methods in enzymology.

Practical Sulfonylation of Amines with 4‐Hydroxybenzenesulfonyl Chloride: In Situ Silylation–Desilylation

J. Levin, Kaapjoo Park, M. Du, 2004 .

Discovery of 3-(4-methanesulfonylphenoxy)-N-[1-(2-methoxy-ethoxymethyl)-1H-pyrazol-3-yl]-5-(3-methylpyridin-2-yl)-benzamide as a novel glucokinase activator (GKA) for the treatment of type 2 diabetes mellitus.

Hyunmi Kim, S. Nam, Byoung Moon Lee, 2014, Bioorganic & medicinal chemistry.

(19)F-encoded combinatorial libraries: discovery of selective metal binding and catalytic peptoids.

M. Pirrung, L. N. Tumey, Kaapjoo Park, 2002, Journal of combinatorial chemistry.

Identification of Novel Orally Available Small Molecule Insulin Mimetics

M. Pirrung, N. Webster, Zhitao Li, 2007, Journal of Pharmacology and Experimental Therapeutics.

Organometallic routes to 2,5-dihydroxy-3-(indol-3-yl)benzoquinones. Synthesis of demethylasterriquinone B4.

M. Pirrung, K. Fujita, Kaapjoo Park, 2005, The Journal of organic chemistry.

Identification of YH-GKA, a novel benzamide glucokinase activator as therapeutic candidate for type 2 diabetes mellitus

Kaapjoo Park, 2012, Archives of Pharmacal Research.

Mitigation of Hematopoietic Syndrome of Acute Radiation Syndrome by 1-Palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) is Associated with Regulation of Systemic Inflammation in a Murine Model of Total-Body Irradiation

Jae Wha Kim, S. Yoon, Kaapjoo Park, 2021, Radiation Research.

Polymer/probe interaction in probe diffusion through a polymer matrix: methyl red diffusion in poly(vinyl acetate)/toluene solutions

Jin Chul Jung, Jaeyoung Lee, J. Jung, 1992 .

Design and synthesis of butynyloxyphenyl beta-sulfone piperidine hydroxamates as TACE inhibitors.

J. Levin, Linhong Sun, Jeremy I Levin, 2006, Bioorganic & medicinal chemistry letters.

Design and Synthesis of Acetylenyl Benzamide Derivatives as Novel Glucokinase Activators for the Treatment of T2DM.

T. Han, Byoung Moon Lee, Dong Hoon Lee, 2015, ACS medicinal chemistry letters.

Compound 19e, a Novel Glucokinase Activator, Protects against Cytokine-Induced Beta-Cell Apoptosis in INS-1 Cells

H. Jun, Y. Oh, Kaapjoo Park, 2017, Front. Pharmacol..