M. Nenquin

发表

Effects of a calcium channel agonist on the electrical, ionic and secretory events in mouse pancreatic B-cells.

H. Meissner, J. Henquin, W. Schmeer, 1985, Biochemical and biophysical research communications.

Congenital Hyperinsulinism Caused by Hexokinase I Expression or Glucokinase-Activating Mutation in a Subset of β-Cells

C. Sempoux, Y. Guiot, J. Henquin, 2013, Diabetes.

cAMP-mediated and metabolic amplification of insulin secretion are distinct pathways sharing independence of β-cell microfilaments.

J. Henquin, M. Nenquin, N. Mourad, 2012, Endocrinology.

Metabolic amplification of insulin secretion by glucose is independent of β-cell microtubules.

J. Henquin, M. Nenquin, N. Mourad, 2011, American journal of physiology. Cell physiology.

Metabolic amplifying pathway increases both phases of insulin secretion independently of beta-cell actin microfilaments.

J. Henquin, M. Nenquin, N. Mourad, 2010, American journal of physiology. Cell physiology.

Tolbutamide and diazoxide influence insulin secretion by changing the concentration but not the action of cytoplasmic Ca2+ in beta-cells.

P. Gilon, J. Henquin, M. Nenquin, 1998, Diabetes.

Inhibition of protein synthesis sequentially impairs distinct steps of stimulus-secretion coupling in pancreatic beta cells.

M. Ravier, P. Gilon, J. Henquin, 2001, Endocrinology.

Inhibition of Protein Synthesis Sequentially Impairs Distinct Steps of Stimulus-secretion Coupling in Pancreatic b Cells*

M. Ravier, P. Gilon, M. García-Barrado, 2000 .

Galanin and epinephrine act on distinct receptors to inhibit insulin release by the same mechanisms including an increase in K+ permeability of the B-cell membrane.

G. Drews, J. Henquin, M. Nenquin, 1990, Endocrinology.

Mechanisms of the Stimulation of Insulin Release by Saturated Fatty Acids: A Study of Palmitate Effects in Mouse β-cells

P. Gilon, J. Henquin, M. Nenquin, 1994, Diabetes.

Signals and pools underlying biphasic insulin secretion.

M. Ravier, J. Henquin, J. Jonas, 2002, Diabetes.

Hierarchy of the β‐cell signals controlling insulin secretion

M. Ravier, P. Gilon, J. Henquin, 2003, European journal of clinical investigation.

Quinine‐induced modifications of insulin release and glucose metabolism by isolated pancreatic islets

J. Henquin, B. Horemans, M. Nenquin, 1975, FEBS letters.

Shortcomings of current models of glucose‐induced insulin secretion

M. Ravier, J. Henquin, M. Nenquin, 2009, Diabetes, obesity & metabolism.

Overnight Culture Unmasks Glucose-induced Insulin Secretion in Mouse Islets Lacking ATP-sensitive K+ Channels by Improving the Triggering Ca2+ Signal*

J. Henquin, M. Nenquin, A. Szollosi, 2007, Journal of Biological Chemistry.

Glucose Stimulates Ca2+ Influx and Insulin Secretion in 2-Week-old β-Cells Lacking ATP-sensitive K+ Channels*

J. Bryan, L. Aguilar-Bryan, J. Henquin, 2007, Journal of Biological Chemistry.

Dynamics of glucose-induced insulin secretion in normal human islets.

J. Kerr-Conte, D. Dufrane, J. Henquin, 2015, American journal of physiology. Endocrinology and metabolism.

SERCA3 ablation does not impair insulin secretion but suggests distinct roles of different sarcoendoplasmic reticulum Ca(2+) pumps for Ca(2+) homeostasis in pancreatic beta-cells.

A. Arredouani, P. Gilon, F. Wuytack, 2002, Diabetes.

Unbound rather than total concentration and saturation rather than unsaturation determine the potency of fatty acids on insulin secretion

J. Henquin, M. Nenquin, C. Warnotte, 1999, Molecular and Cellular Endocrinology.

In Vivo and In Vitro Glucose-Induced Biphasic Insulin Secretion in the Mouse Pattern and Role of Cytoplasmic Ca 2 and Amplification Signals in-Cells

B. Ahrén, J. Henquin, M. Nenquin, 2006 .

Glucose-induced cytosolic pH changes in beta-cells and insulin secretion are not causally related: studies in islets lacking the Na+/H+ exchangeR NHE1.

P. Moulin, J. Henquin, J. Jonas, 2007, The Journal of biological chemistry.

Forskolin suppresses the slow cyclic variations of glucose-induced electrical activity in pancreatic B cells.

H. Meissner, J. Henquin, W. Schmeer, 1984, Biochemical and biophysical research communications.

Mechanism of the stimulation of insulin release in vitro by HB 699, a benzoic acid derivative similar to the non-sulphonylurea moiety of glibenclamide

H. Meissner, J. Henquin, M. Garrino, 1985, Diabetologia.

Multiple effects and stimulation of insulin secretion by the tyrosine kinase inhibitor genistein in normal mouse islets

P. Gilon, J. Henquin, J. Jonas, 1995, British journal of pharmacology.

The Elevation of Glutamate Content and the Amplification of Insulin Secretion in Glucose-stimulated Pancreatic Islets Are Not Causally Related*

M. Ravier, G. Bertrand, J. Henquin, 2002, The Journal of Biological Chemistry.

Magnesium uptake by pancreatic islet cells is modulated by stimulators and inhibitors of the B-cell function.

J. Henquin, M. Cogneau, M. Nenquin, 1986, European journal of biochemistry.

Relative contribution of Ca2+‐dependent and Ca2+‐independent mechanisms to the regulation of insulin secretion by glucose

J. Henquin, Yoshihiko Sato, M. Nenquin, 1998, FEBS letters.

Both Triggering and Amplifying Pathways Contribute to Fuel-induced Insulin Secretion in the Absence of Sulfonylurea Receptor-1 in Pancreatic β-Cells*

J. Bryan, L. Aguilar-Bryan, J. Henquin, 2004, Journal of Biological Chemistry.

Glucose controls cytosolic Ca2+ and insulin secretion in mouse islets lacking adenosine triphosphate-sensitive K+ channels owing to a knockout of the pore-forming subunit Kir6.2.

M. Ravier, S. Seino, T. Miki, 2009, Endocrinology.

In vitro insulin secretion by pancreatic tissue from infants with diazoxide-resistant congenital hyperinsulinism deviates from model predictions.

C. Sempoux, C. Bellanné-Chantelot, P. de Lonlay, 2011, The Journal of clinical investigation.

The effects of cesium chloride on insulin release, ionic fluxes and membrane potential in pancreatic B-cells.

G. Paolisso, H. Meissner, J. Henquin, 1985, Biochimica et biophysica acta.

Sparteine increases insulin release by decreasing the K+ permeability of the B-cell membrane.

G. Paolisso, H. Meissner, J. Henquin, 1985, Biochemical pharmacology.

Muscarinic stimulation exerts both stimulatory and inhibitory effects on the concentration of cytoplasmic Ca2+ in the electrically excitable pancreatic B-cell.

P. Gilon, J. Henquin, M. Nenquin, 1995, The Biochemical journal.

Insulin secretion in islets from mice with a double knockout for the dense core vesicle proteins islet antigen-2 (IA-2) and IA-2beta.

A. Kubosaki, A. Notkins, J. Henquin, 2008, The Journal of endocrinology.

Activators of PKA and Epac distinctly influence insulin secretion and cytosolic Ca2+ in female mouse islets stimulated by glucose and tolbutamide.

J. Henquin, M. Nenquin, 2014, Endocrinology.

Nutrient control of insulin secretion in perifused adult pig islets.

D. Dufrane, J. Henquin, M. Nenquin, 2007, Diabetes & metabolism.

Two sites of glucose control of insulin release with distinct dependence on the energy state in pancreatic B-cells.

P. Gilon, J. Henquin, P. Detimary, 1994, The Biochemical journal.

Diazoxide and D600 Inhibition of Insulin Release: Distinct Mechanisms Explain the Specificity for Different Stimuli

J. Henquin, M. Nenquin, T. Tamagawa, 1982, Diabetes.

Disruption and stabilization of β‐cell actin microfilaments differently influence insulin secretion triggered by intracellular Ca2+ mobilization or store‐operated Ca2+ entry

J. Henquin, M. Nenquin, N. Mourad, 2012, FEBS letters.

Distinct mechanisms for two amplification systems of insulin release.

M. Bozem, J. Henquin, W. Schmeer, 1987, The Biochemical journal.

Human Insulinomas Show Distinct Patterns of Insulin Secretion In Vitro

C. Sempoux, Y. Guiot, J. Henquin, 2015, Diabetes.

Sulphonylurea receptor‐1, sulphonylureas and amplification of insulin secretion by Epac activation in β cells

J. Henquin, M. Nenquin, 2016, Diabetes, obesity & metabolism.

Glucose modulates Mg2+fluxes in pancreatic islet cells

J. Henquin, M. Cogneau, M. Nenquin, 1983, Nature.

Pharmacological control of 86Rb efflux from mouse pancreatic islets.

G. Paolisso, J. Henquin, M. Garrino, 1986, Advances in experimental medicine and biology.

Nutrient insulin secretagogues decrease 45Ca2+ efflux from islet cells by a mechanism other than the inhibition of the Na+‐Ca2+ countertransport

J. Henquin, M. Garrino, M. Nenquin, 1985, FEBS letters.

Effects of acute sodium omission on insulin release, ionic flux and membrane potential in mouse pancreatic B-cells.

J. Henquin, W. Schmeer, M. Nenquin, 1988, Biochimica et biophysica acta.

Distinct effects of acetylcholine and glucose on 45calcium and 86rubidium efflux from mouse pancreatic islets

J. Henquin, M. Nenquin, P. Awouters, 1984, FEBS letters.

Vanadate stimulation of insulin release in normal mouse islets.

P. Gilon, G. Drews, J. Henquin, 1991, The Journal of biological chemistry.

Mechanisms of the stimulation of insulin release by arginine-vasopressin in normal mouse islets.

G. Drews, J. Henquin, T. Plant, 1990, The Journal of biological chemistry.

Immaturity of insulin secretion by pancreatic islets isolated from one human neonate

J. Henquin, M. Nenquin, 2017, Journal of diabetes investigation.

Comparison of the inhibition of insulin release by activation of adenosine and alpha 2-adrenergic receptors in rat beta-cells.

G. Bertrand, J. Henquin, M. Nenquin, 1989, The Biochemical journal.

The muscarinic receptor subtype in mouse pancreatic B‐cells

J. Henquin, M. Nenquin, 1988, FEBS letters.

In vivo and in vitro glucose-induced biphasic insulin secretion in the mouse: pattern and role of cytoplasmic Ca2+ and amplification signals in beta-cells.

Myriam Nenquin, B. Ahrén, J. Henquin, 2006, Diabetes.

Muscarinic control of pancreatic B cell function involves sodium-dependent depolarization and calcium influx.

M. Bozem, J. Henquin, J C Henquin, 1988, Endocrinology.

Amplification of insulin secretion by acetylcholine or phorbol ester is independent of β-cell microfilaments and distinct from metabolic amplification

J. Henquin, M. Nenquin, N. Mourad, 2013, Molecular and Cellular Endocrinology.

Inhibition of Protein Synthesis Sequentially Impairs Distinct Steps of Stimulus-secretion Coupling in Pancreatic β Cells* * This work was supported by the Interuniversity Poles of Attraction Program (P4/21), Belgian State Prime Minister's Office, Federal Office for Scientific, Technical, and Cultura

M. Ravier, P. Gilon, J. Henquin, 2001, Endocrinology.

Nutrient Control of Insulin Secretion in Isolated Normal Human Islets

Myriam Nenquin, Denis Dufrane, D. Dufrane, 2006, Diabetes.

Pharmacological stimulation and inhibition of insulin secretion in mouse islets lacking ATP‐sensitive K+ channels

J. Henquin, M. Nenquin, A. Szollosi, 2010, British journal of pharmacology.

RESEARCH PAPER Pharmacological stimulation and inhibition of insulin secretion in mouse islets lacking

J. Henquin, M. Nenquin, A. Szollosi, 2010 .

Stimulation of insulin release by benzoic acid derivatives related to the non-sulphonylurea moiety of glibenclamide: structural requirements and cellular mechanisms.

J. Henquin, M. Garrino, M. Nenquin, 1987, European journal of pharmacology.

Dynamics and Regulation of Insulin Secretion in Pancreatic Islets from Normal Young Children

J. Henquin, M. Nenquin, 2016, PloS one.

Pharmacological approach to understanding the control of insulin secretion in human islets

V. Gmyr, J. Kerr-Conte, D. Dufrane, 2017, Diabetes, obesity & metabolism.

The ionic, electrical, and secretory effects of protein kinase C activation in mouse pancreatic B-cells: studies with a phorbol ester.

M. Bozem, J. Henquin, M. Nenquin, 1987, Endocrinology.

The Oscillatory Behavior of Pancreatic Islets from Mice with Mitochondrial Glycerol-3-phosphate Dehydrogenase Knockout*

M. Ravier, T. Kadowaki, K. Eto, 2000, The Journal of Biological Chemistry.

Insulin secretion in response to high extracellular calcium is not a pathognomonic feature of insulinoma cells.

F. Pattou, J. Henquin, M. Nenquin, 2017, Diabetes & metabolism.

Insulin secretion in islets from mice with a double knockout for the dense core vesicle proteins islet antigen-2 (IA-2) and IA-2beta.

A. Kubosaki, A. Notkins, J. Henquin, 2008, The Journal of endocrinology.

M. Ravier, P. Gilon, J. Henquin, 2001, Endocrinology.

Inhibition of Protein Synthesis Sequentially Impairs Distinct Steps of Stimulus-secretion Coupling in Pancreatic b Cells*

M. Ravier, P. Gilon, M. García-Barrado, 2000 .