M. Labadia

发表

Agonist versus antagonist induce distinct thermodynamic modes of co-factor binding to the glucocorticoid receptor.

Elda Gautschi, N. Farrow, C. A. Grygon, 2007, Biophysical chemistry.

Catalysis and Function of the p38α·MK2a Signaling Complex

C. Pargellis, B. Werneburg, S. Lukas, 2004 .

Discovery of 1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxide analogs as new RORC modulators.

I. Muegge, J. Horan, Melissa Hill-Drzewi, 2015, Bioorganic & medicinal chemistry letters.

Identification of a novel class of succinyl-nitrile-based Cathepsin S inhibitors.

M. Hao, D. White, K. Crane, 2007, Bioorganic & medicinal chemistry letters.

Involvement of GATA3 in Protein Kinase C θ‐induced Th2 cytokine expression

Jianfei Yang, D. White, M. Brown, 2006 .

High-affinity interactions of tumor necrosis factor receptor-associated factors (TRAFs) and CD40 require TRAF trimerization and CD40 multimerization.

T. Alber, M. Kehry, R. Ingraham, 1999, Biochemistry.

The primary structure of a human MAP kinase activated protein kinase 2.

C. Huang, A. Gilchrist, Y. Ai, 1994, Biochemical and biophysical research communications.

Discovery of a Series of Pyrazinone RORγ Antagonists and Identification of the Clinical Candidate BI 730357.

S. Brunette, R. Fryer, R. Sibley, 2021, ACS medicinal chemistry letters.

A synthetic peptide containing a predominant protein kinase C site within p47phox inhibits the NADPH oxidase in intact neutrophils

Chi‐Kuang Huang, M. Labadia, Y. Zu, 1996, Journal of leukocyte biology.

Paradoxical Augmentation of Experimental Spondyloarthritis by RORC Inhibition in HLA-B27 Transgenic Rats

D. Baeten, G. Nabozny, Mohamed F. Mandour, 2021, Frontiers in Immunology.

Inhibition of HIV-1 replication by a nonnucleoside reverse transcriptase inhibitor.

J. Adams, K. Grozinger, J. Wu, 1990, Science.

Pathogenic mechanisms and experimental models of multiple sclerosis

M. Brown, A. Slavin, M. Labadia, 2010, Autoimmunity.

RORγt inhibition selectively targets IL-17 producing iNKT and γδ-T cells enriched in Spondyloarthritis patients

Yvan Saeys, Dustin Smith, Sofie Van Gassen, 2019, Nature Communications.

An RORγt Oral Inhibitor Modulates IL-17 Responses in Peripheral Blood and Intestinal Mucosa of Crohn's Disease Patients

A. Salas, A. Corraliza, G. Nabozny, 2018, Front. Immunol..

The Rap1A protein enhances protein kinase C activity in vitro.

G. Bokoch, C. Huang, M. Labadia, 1993, Biochemical and biophysical research communications.

Structural studies unravel the active conformation of apo RORγt nuclear receptor and a common inverse agonism of two diverse classes of RORγt inhibitors

I. Muegge, N. Farrow, B. Cook, 2017, The Journal of Biological Chemistry.

Activation of MAP kinase-activated protein kinase 2 in human neutrophils after phorbol ester or fMLP peptide stimulation.

R. Sha’afi, C. Huang, A. Gilchrist, 1996, Blood.

Epstein‐Barr virus‐induced gene 3 negatively regulates IL‐17, IL‐22 and RORγt

Jianfei Yang, H. Xiong, L. Mayer, 2008, European journal of immunology.

The determination and correlation of molecular and cellular equilibrium Kd and kinetic k(off) values for small molecule allosteric antagonists of LFA-1.

J. Woska, D. Jeanfavre, P. Giblin, 2007, Biochemical pharmacology.

RORγt inhibition selectively targets IL-17 producing iNKT and γδ-T cells enriched in Spondyloarthritis patients

Y. Saeys, S. van Calenbergh, K. Venken, 2019, Nature Communications.

Catalysis and function of the p38 alpha.MK2a signaling complex.

C. Pargellis, B. Werneburg, S. Lukas, 2004, Biochemistry.

Design and synthesis of dipeptide nitriles as reversible and potent Cathepsin S inhibitors.

Yong Wang, Ming-Hong Hao, M. Hao, 2002, Journal of medicinal chemistry.

Molecular regulation of the interaction between leukocyte function-associated antigen-1 and soluble ICAM-1 by divalent metal cations.

D. Jeanfavre, M. Morelock, M. Labadia, 1998, Journal of immunology.

Soluble ICAM-1 by Divalent Metal Cations Leukocyte Function-Associated Antigen-1 and Molecular Regulation of the Interaction Between

D. Jeanfavre, M. Morelock, M. Labadia, 2017 .

Discovery and characterization of a substrate selective p38alpha inhibitor.

C. Pargellis, B. Werneburg, S. Lukas, 2004, Biochemistry.

Structural and biochemical analysis of signal transduction by the TRAF family of adapter proteins.

T. Alber, B. Werneburg, M. Kehry, 1999, Cold Spring Harbor symposia on quantitative biology.

The design of potent hydrazones and disulfides as cathepsin S inhibitors.

Jeffrey D Peterson, J. Peterson, D. White, 2003, Bioorganic & medicinal chemistry.

Interaction between the SH2 domains of ZAP-70 and the tyrosine-based activation motif 1 sequence of the zeta subunit of the T-cell receptor.

S. Lukas, S. Jakes, R. Ingraham, 1997, Archives of biochemistry and biophysics.

Role of Adherence vs. Spreading in the Induction of Membrane‐Associated Interleukin‐1 on Mouse Peritoneal Macrophages

R. Rothlein, R. Faanes, M. Labadia, 1990, Journal of leukocyte biology.

Binding affinities of the SH2 domains of ZAP‐70, p56/ck and Shc to the chain ITAMs of the T‐cell receptor determined by surface plasmon resonance

S. Jakes, R. Ingraham, J. Schembri-King, 1996, Journal of leukocyte biology.