Hongwei Zhang

发表

Quantitation of drug metabolites in the absence of pure metabolite standards by high-performance liquid chromatography coupled with a chemiluminescence nitrogen detector and mass spectrometer.

T. Olah, Yuzhong Deng, Jing-tao Wu, 2004, Rapid communications in mass spectrometry : RCM.

The Development and Implementation of LC/MS-Based Bioanalytical Methods for the Quantification of Protein Therapeutics in Drug Discovery

Yulia Benitex, T. Olah, D. Drexler, 2013 .

Modeling and Simulation of the Pharmacokinetics and Target Engagement of an Antagonist Monoclonal Antibody to Interferon‐γ–Induced Protein 10, BMS‐986184, in Healthy Participants to Guide Therapeutic Dosing

L. Gibiansky, Subhashish Banerjee, T. Leil, 2020, Clinical pharmacology in drug development.

Bioanalytical strategies for developing highly sensitive liquid chromatography/tandem mass spectrometry based methods for the peptide GLP-1 agonists in support of discovery PK/PD studies.

T. Olah, B. Xin, Hongwei Zhang, 2011, Rapid communications in mass spectrometry : RCM.

A peptide immunoaffinity LC-MS/MS strategy for quantifying the GPCR protein, S1PR1 in human colon biopsies.

Eugene Ciccimaro, T. Olah, P. Shipkova, 2020, Bioanalysis.

High-throughput screening of 756 chemical contaminants in aquaculture products using liquid chromatography/quadrupole time-of-flight mass spectrometry

R. Tang, Haohao Wu, Suqin Zhu, 2022, Food chemistry: X.

Chemo- and Site-Selective Lysine Modification of Peptides and Proteins under Native Conditions Using the Water-Soluble Zolinium.

Weiliang Zhu, Kaixian Chen, Bo Li, 2022, Journal of medicinal chemistry.

Synthesis and Antiobesity Properties of 6-(4-Chlorophenyl)-3-(4-((3,3-difluoro-1-hydroxycyclobutyl)methoxy)-3-methoxyphenyl)thieno[3,2-d]pyrimidin-4(3H)-one (BMS-814580): A Highly Efficacious Melanin Concentrating Hormone Receptor 1 (MCHR1) Inhibitor.

E. Janovitz, D. Longhi, Christine S. Huang, 2016, Journal of Medicinal Chemistry.

Discovery of a Phenylpyrazole Amide ROCK Inhibitor as a Tool Molecule for in vivo Studies.

David S. Taylor, J. Sack, Chunhong Yan, 2020, Bioorganic & medicinal chemistry letters.

Development of a highly sensitive liquid chromatography/tandem mass spectrometry method to quantify total and free levels of a target protein, interferon-gamma-inducible protein-10, at picomolar levels in human serum.

T. Olah, A. Tymiak, B. Xin, 2014, Rapid communications in mass spectrometry : RCM.

Dihydropyrrolopyrazol-6-one MCHR1 antagonists for the treatment of obesity: Insights on in vivo efficacy from a novel FLIPR assay setup.

R. Sridhar, D. Longhi, Christine S. Huang, 2015, Bioorganic & medicinal chemistry letters.

Immunoaffinity LC-MS/MS for quantitative determination of a free and total protein target as a target engagement biomarker.

Eugene Ciccimaro, T. Olah, P. Shipkova, 2017, Bioanalysis.

A multifunctional anti-AD approach: Design, synthesis, X-ray crystal structure, biological evaluation and molecular docking of chrysin derivatives.

Chang Liu, J Wu, Rui Shen, 2022, European journal of medicinal chemistry.

A novel function of CXCL10 in mediating monocyte production of proinflammatory cytokines

M. Struthers, T. Olah, L. Salter-Cid, 2017, Journal of leukocyte biology.

Disconnection between the early onset anorectic effects by C75 and hypothalamic fatty acid synthase inhibition in rodents.

B. Largent, R. Taub, Cecilia L Chi, 2005, European journal of pharmacology.

Tandem mass spectrometry with online high-flow reversed-phase extraction and normal-phase chromatography on silica columns with aqueous-organic mobile phase for quantitation of polar compounds in biological fluids.

T. Olah, Yuzhong Deng, Jing-tao Wu, 2005, Rapid communications in mass spectrometry : RCM.

Identification of a nonbasic melanin hormone receptor 1 antagonist as an antiobesity clinical candidate.

J. Barrish, E. Janovitz, D. Longhi, 2014, Journal of medicinal chemistry.

Non-basic azolotriazinone MCHR1 antagonists for the treatment of obesity: An empirical brain-exposures-driven candidate selection for in vivo efficacy studies.

S. Radhakrishnan, D. Longhi, Christine S. Huang, 2015, Bioorganic & medicinal chemistry letters.

Distinguishing a phosphate ester prodrug from its isobaric sulfate metabolite by mass spectrometry without the metabolite standard.

Steven T. Wu, M. Jemal, S. Bonacorsi, 2009, Rapid communications in mass spectrometry : RCM.