P. Polepally

Novel orally available salvinorin A analog PR-38 protects against experimental colitis and reduces abdominal pain in mice by interaction with opioid and cannabinoid receptors.

W. Krajewska, R. Kordek, J. Fichna, 2014, Biochemical pharmacology.

Kappa-opioid receptor-selective dicarboxylic ester-derived salvinorin A ligands.

B. Roth, D. Ferreira, E. Vardy, 2013, Bioorganic & medicinal chemistry letters.

Salvinorin A analogues PR‐37 and PR‐38 attenuate compound 48/80‐induced itch responses in mice

B. Roth, J. Fichna, J. Do Régo, 2015, British journal of pharmacology.

Plurality of anxiety and depression alteration mechanism by oleanolic acid

J. Fajemiroye, E. A. Costa, P. C. Ghedini, 2014, Journal of psychopharmacology.

Critical interactions between opioid and cannabinoid receptors during tolerance and physical dependence development to opioids in the murine gastrointestinal tract: proof of concept

J. Fichna, M. Talar, M. Zielińska, 2021, Pharmacological Reports.

Identification of Novel Functionally Selective κ-Opioid Receptor Scaffolds

B. Roth, J. Javitch, M. Rives, 2014, Molecular Pharmacology.

Oleanolic acid acrylate elicits antidepressant-like effect mediated by 5-HT1A receptor

B. Tekwani, J. Fajemiroye, E. A. Costa, 2015, Scientific Reports.

Michael acceptor approach to the design of new salvinorin A-based high affinity ligands for the kappa-opioid receptor.

V. Setola, B. Roth, E. Vardy, 2014, European journal of medicinal chemistry.

The G Protein–Biased κ-Opioid Receptor Agonist RB-64 Is Analgesic with a Unique Spectrum of Activities In Vivo

B. Roth, C. Malanga, J. Robinson, 2015, The Journal of Pharmacology and Experimental Therapeutics.