E. Park

发表

Small molecule inhibition of CBP/catenin interactions eliminates drug resistant clones in acute lymphoblastic leukemia

C. Nguyên, M. Kahn, M. McMillan, 2013, Oncogene.

Integrin α6 mediates drug resistance of acute lymphoblastic B-cell leukemia.

T. Graeber, M. Oberley, N. Heisterkamp, 2020, Blood.

BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia

Martin C. Müller, A. Melnick, W. Hofmann, 2011, The Journal of experimental medicine.

BCL 6-mediated repression of p 53 is critical for leukemia stem cell survival in chronic myeloid leukemia

Martin C. Müller, A. Melnick, W. Hofmann, 2011 .

Signaling thresholds and negative B cell selection in acute lymphoblastic leukemia

M. Loh, T. Graeber, J. Coligan, 2015, Nature.

B cell origin of non-T cell acute lymphoblastic leukemia. A model for discrete stages of neoplastic and normal pre-B cell differentiation.

S. Korsmeyer, S. Sallan, R. Mayer, 1984, The Journal of clinical investigation.

Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre–B ALL

S. Frietze, O. Witte, S. Smale, 2017, The Journal of experimental medicine.

Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia.

M. Loh, T. Graeber, J. Coligan, 2016 .

Human B Cell-Associated Antigens: Expression on Normal and Malignant B Lymphocytes

L. Nadler, S. Schlossman, E. Park, 1984 .

The B Cell-Restricted Glycoprotein (B2) Is the Receptor for Epstein-Barr Virus

D. Fisher, A. Boyd, L. Nadler, 1986 .

Induction of human B cell antigens in non-T cell acute lymphoblastic leukemia.

S. Sallan, J. Ritz, L. Nadler, 1982, The Journal of clinical investigation.

Targeting survivin overcomes drug resistance in acute lymphoblastic leukemia.

M. Loh, M. Kahn, N. Heisterkamp, 2011, Blood.

Antigens on human plasma cells identified by monoclonal antibodies.

L. Nadler, S. Schlossman, R. Leonard, 1983, Journal of immunology.

BCL6 enables Ph+ acute lymphoblastic leukemia cells to survive BCR-ABL1 kinase inhibition

Sebastian Herzog, Hong Wu, Eugene Park, 2011, Nature.

Erk Negative Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia.

K. Coombes, Nianxiang Zhang, A. Melnick, 2015, Cancer cell.

Self-enforcing Feedback Activation between Bcl6 and Pre-b Cell Receptor Signaling Defines a Distinct Subtype of Acute Lymphoblastic Leukemia Self-enforcing Feedback Activation between Bcl6 and Pre-b Cell Receptor Signaling Defines a Distinct Subtype of Acute Lymphoblastic Leukemia Figure 1. Expressi

M. Loh, A. Melnick, R. Roeder, 2022 .

Integrin alpha4 blockade sensitizes drug resistant pre-B acute lymphoblastic leukemia to chemotherapy.

M. Loh, N. Heisterkamp, H. Koo, 2013, Blood.

Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia

K. Schwarz, M. Lieber, D. Schatz, 2015, Nature Immunology.

Pre–B cell receptor–mediated cell cycle arrest in Philadelphia chromosome–positive acute lymphoblastic leukemia requires IKAROS function

N. Heisterkamp, J. Groffen, H. Jäck, 2009, The Journal of experimental medicine.

B4, a human B lymphocyte-associated antigen expressed on normal, mitogen-activated, and malignant B lymphocytes.

G. Marti, L. Nadler, J. Daley, 1983, Journal of immunology.

MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia.

M. Loh, D. Teachey, Jinhua Wang, 2015, Blood.

Identification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia

E. Passegué, A. Melnick, H. Schjerven, 2015, Nature Communications.

Targeting the vulnerability to NAD+ depletion in B-cell acute lymphoblastic leukemia

E. Baloglu, Y. Chen, S. Gery, 2018, Leukemia.

Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia.

A. Letai, H. Döhner, V. Gaidzik, 2014, Cancer discovery.

MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199

K. Coombes, A. Letai, Nianxiang Zhang, 2015, Cell reports.

AMD3100 sensitizes acute lymphoblastic leukemia cells to chemotherapy in vivo

N. Heisterkamp, J. Groffen, A. Yang, 2011, Blood cancer journal.

Role of Survivin in Drug Resistant B-Cell Acute Lymphoblastic Leukemia.

C. Nguyên, M. Kahn, N. Heisterkamp, 2009 .

Adjuvant CD49d Blockade Eradicates Chemoresistant ALL

M. Loh, N. Heisterkamp, H. Koo, 2010 .

Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia.

A. Letai, H. Döhner, V. Gaidzik, 2014, Cancer discovery.

Targeting survivin overcomes drug resistance in acute lymphoblastic leukemia.

M. Kahn, N. Heisterkamp, W. Hofmann, 2011, Blood.

Integrin alpha4 blockade sensitizes drug resistant pre-B acute lymphoblastic leukemia to chemotherapy.

N. Heisterkamp, H. Koo, W. Hofmann, 2013, Blood.

MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia.

D. Teachey, Jinhua Wang, M. Garabedian, 2015, Blood.

Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia.

T. Graeber, J. Coligan, T. Mak, 2016 .

Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia.

A. Melnick, R. Roeder, B. Druker, 2015, Cancer cell.

BCL6 Is Required for Leukemia-Initiation and Self-Renewal Signaling in Chronic Myeloid Leukemia.

A. Melnick, W. Hofmann, G. Martinelli, 2009 .

CD25 (IL2RA) Orchestrates Negative Feedback Control and Stabilizes Oncogenic Signaling Strength in Acute Lymphoblastic Leukemia

A. Melnick, A. Abbas, S. Kornblau, 2015 .