A. Jabbour

发表

Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim

D. Vaux, J. Heraud, A. Strasser, 2009, Cell Death and Differentiation.

Co-fuse: a new class discovery analysis tool to identify and prioritize recurrent fusion genes from RNA-sequencing data

A. Zannettino, E. Nievergall, S. Paisitkriangkrai, 2018, Molecular Genetics and Genomics.

Cell death provoked by loss of interleukin-3 signaling is independent of Bad, Bim, and PI3 kinase, but depends in part on Puma.

C. Borner, D. Vaux, J. Heraud, 2006, Blood.

Akt1 is the principal Akt isoform regulating apoptosis in limiting cytokine concentrations

R. Pearson, J. Sandow, P. Ekert, 2013, Cell Death and Differentiation.

Caspase‐2 is resistant to inhibition by inhibitor of apoptosis proteins (IAPs) and can activate caspase‐7

P. Ekert, C. Hawkins, A. Jabbour, 2005, The FEBS journal.

The p35 relative, p49, inhibits mammalian and Drosophila caspases including DRONC and protects against apoptosis

P. Ekert, E. Coulson, D. Ashley, 2002, Cell Death and Differentiation.

Modeling Metazoan Apoptotic Pathways in Yeast.

C. Hawkins, A. Jabbour, Tanja Kitevska, 2016, Methods in molecular biology.

p53-Dependent Transcriptional Responses to Interleukin-3 Signaling

P. Ekert, L. Gordon, C. Kok, 2012, PloS one.

Hoxb8 regulates expression of microRNAs to control cell death and differentiation

G. Goodall, A. Bert, G. Brumatti, 2013, Cell Death and Differentiation.

Triggering of apoptosis by Puma is determined by the threshold set by prosurvival Bcl-2 family proteins.

Paul G Ekert, D. Vaux, P. Ekert, 2008, Journal of molecular biology.

Human Bcl-2 cannot directly inhibit the Caenorhabditis elegans Apaf-1 homologue CED-4, but can interact with EGL-1

T. Lithgow, D. Vaux, D. Ashley, 2006, Journal of Cell Science.

Myeloid progenitor cells lacking p53 exhibit delayed up-regulation of Puma and prolonged survival after cytokine deprivation.

C. Borner, A. Strasser, R. Pearson, 2010, Blood.

Deletion of IKK2 in haematopoietic cells of adult mice leads to elevated interleukin-6, neutrophilia and fatal gastrointestinal inflammation

J. Vince, Sheila Dias, A. Jabbour, 2021, Cell death & disease.

The oncogenic properties of EWS/WT1 of desmoplastic small round cell tumors are unmasked by loss of p53 in murine embryonic fibroblasts

David M. Thomas, P. Ekert, M. Salmanidis, 2013, BMC Cancer.

Enhancing venetoclax activity in acute myeloid leukemia by co-targeting MCL1

P. Ekert, A. Roberts, A. Wei, 2018, Leukemia.

Cytokine Deprivation and Cell Death

P. Ekert, A. Jabbour, 2011 .

Targeting acute myeloid leukemia by dual inhibition of PI3K signaling and Cdk9-mediated Mcl-1 transcription.

Michael W. Parker, Stefan P. Glaser, S. Nilsson, 2013, Blood.

HoxA9 regulated Bcl-2 expression mediates survival of myeloid progenitors and the severity of HoxA9-dependent leukemia

Toru Okamoto, Stefan P. Glaser, Paul G Ekert, 2013, Oncotarget.

Co-fuse: a new class discovery analysis tool to identify and prioritize recurrent fusion genes from RNA-sequencing data

A. Zannettino, E. Nievergall, S. Paisitkriangkrai, 2018, Molecular Genetics and Genomics.

Cytokine receptor signaling activates an IKK-dependent phosphorylation of PUMA to prevent cell death

M. Condina, J. Sandow, P. Ekert, 2011, Cell Death and Differentiation.

Cytoplasmic p53 is not required for PUMA-induced apoptosis

J. Heraud, P. Ekert, J. Silke, 2008, Cell Death and Differentiation.

The Caenorhabditis elegans CED-9 protein does not directly inhibit the caspase CED-3, in vitro nor in yeast

P. Ekert, D. Ashley, C. Hawkins, 2004, Cell Death and Differentiation.

Targeting acute myeloid leukemia by dual inhibition of PI3K signaling and Cdk9-mediated Mcl-1 transcription.

Stefan P. Glaser, S. Nilsson, Angel F. Lopez, 2013, Blood.

The p35 Family of Apoptosis Inhibitors

C. Hawkins, A. Jabbour, 2004 .