N. Khan

发表

Wogonin, a natural flavonoid, intercalates with genomic DNA and exhibits protective effects in IL-1β stimulated osteoarthritis chondrocytes.

I. Ahmad, T. Haqqi, N. Khan, 2017, Chemico-biological interactions.

Pharmacogenetic landscape of clopidogrel in north Indians suggest distinct interpopulation differences in allele frequencies.

N. Tandon, V. Scaria, D. Bharadwaj, 2014, Pharmacogenomics.

Genetic epidemiology of pharmacogenetic variations in CYP2C9, CYP4F2 and VKORC1 genes associated with warfarin dosage in the Indian population.

N. Tandon, V. Scaria, S. Brahmachari, 2014, Pharmacogenomics.

Antioxidant supplementation enhances bacterial peritonitis in mice by inhibiting phagocytosis.

N. Jawali, M. Goswami, R. Checker, 2014, Journal of medical microbiology.

Differential immunotoxic effects of ethanol on murine EL-4 lymphoma and normal lymphocytes is mediated through increased ROS production and activation of p38MAPK

J. Shukla, N. Khan, V. S. Thakur, 2012, Immunopharmacology and immunotoxicology.

A wogonin-rich-fraction of Scutellaria baicalensis root extract exerts chondroprotective effects by suppressing IL-1β-induced activation of AP-1 in human OA chondrocytes

A. Haseeb, T. Haqqi, N. Khan, 2017, Scientific Reports.

l-Arginine Mitigates Radiation-Induced Early Changes in Cardiac Dysfunction: The Role of Inflammatory Pathways

J. Shukla, N. Khan, V. S. Thakur, 2011, Radiation research.

Deep sequencing and analyses of miRNAs, isomiRs and miRNA induced silencing complex (miRISC)-associated miRNome in primary human chondrocytes

I. Ahmad, M. Makki, A. Haseeb, 2017, Scientific Reports.

Parkin clearance of dysfunctional mitochondria regulates ROS levels and increases survival of human chondrocytes.

I. Ahmad, T. Haqqi, N. Khan, 2017, Osteoarthritis and cartilage.

Directional dominance on stature and cognition in diverse human populations

Laura J. Scott, Claude Bouchard, Christian Gieger, 2015, Nature.

Vitamin K3 suppressed inflammatory and immune responses in a redox-dependent manner

K. Sainis, R. Patwardhan, R. Checker, 2011, Free radical research.

Comparative transcriptomic analysis identifies distinct molecular signatures and regulatory networks of chondroclasts and osteoclasts

M. Hansen, H. Drissi, J. Lorenzo, 2020, Arthritis Research & Therapy.

A standardized extract of Butea monosperma (Lam.) flowers suppresses the IL-1β-induced expression of IL-6 and matrix-metalloproteases by activating autophagy in human osteoarthritis chondrocytes.

T. Haqqi, N. Khan, M. Ansari, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Sucrose, But Not Glucose, Blocks IL1‐β‐Induced Inflammatory Response in Human Chondrocytes by Inducing Autophagy via AKT/mTOR Pathway

T. Haqqi, N. Khan, M. Ansari, 2017, Journal of cellular biochemistry.

Differential chondrogenic differentiation between iPSC derived from healthy and OA cartilage is associated with changes in epigenetic regulation and metabolic transcriptomic signatures

H. Drissi, L. Mortensen, R. Guzzo, 2022, bioRxiv.

Single-cell RNA-seq identifies unique transcriptional landscapes of human nucleus pulposus and annulus fibrosus cells

G. Gibson, H. Drissi, N. Khan, 2020, Scientific Reports.

Role of immunoregulatory transcription factors in differential immunomodulatory effects of tocotrienols.

T. Devasagayam, R. Patwardhan, R. Checker, 2011, Free radical biology & medicine.

Acute Radiation Syndrome at Crossroads of Protection and Therapy

A. Giri, Divya Narayanan, N. Khan, 2013 .

Genetic Inactivation of ZCCHC6 Suppresses Interleukin‐6 Expression and Reduces the Severity of Experimental Osteoarthritis in Mice

K. Novak, T. Haqqi, N. Khan, 2019, Arthritis & rheumatology.

Immunomodulatory and immunotoxic effects of bilirubin: molecular mechanisms

N. Khan, T. Poduval, N. M. Khan, 2011, Journal of leukocyte biology.

PHLPP1 deficiency protects against age‐related intervertebral disc degeneration

H. Drissi, S. Illien-Junger, N. Khan, 2022, JOR spine.

Pro-oxidants ameliorate radiation-induced apoptosis through activation of the calcium-ERK1/2-Nrf2 pathway.

K. Sainis, R. Checker, D. Sharma, 2011, Free radical biology & medicine.

Wogonin, a plant derived small molecule, exerts potent anti‐inflammatory and chondroprotective effects through the activation of ROS/ERK/Nrf2 signaling pathways in human Osteoarthritis chondrocytes

Pratap Devarapalli, A. Haseeb, T. Haqqi, 2017, Free radical biology & medicine.

Inhibition of cartilage degradation and suppression of PGE2 and MMPs expression by pomegranate fruit extract in a model of posttraumatic osteoarthritis.

N. Akhtar, T. Haqqi, N. Khan, 2017, Nutrition.

γ-Tocotrienol induces apoptosis in human T cell lymphoma through activation of both intrinsic and extrinsic pathways.

T. Devasagayam, R. Patwardhan, R. Checker, 2011, Current pharmaceutical design.

Derivation of notochordal cells from human embryonic stem cells reveals unique regulatory networks by single cell‐transcriptomics

G. Gibson, H. Drissi, P. Maye, 2019, Journal of cellular physiology.

Epigenetics in osteoarthritis: Potential of HDAC inhibitors as therapeutics

T. Haqqi, N. Khan, 2017, Pharmacological research.

Sexual Dimorphism in Differentiating Osteoclast Precursors Demonstrates Enhanced Inflammatory Pathway Activation in Female Cells

H. Drissi, P. Zhou, Seyeon Bae, 2021, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Current challenges to overcome in the management of type 2 diabetes mellitus and associated neurological disorders.

M. Kamal, Ausaf Ahmad, Ghulam M Ashraf, 2014, CNS & neurological disorders drug targets.

A Polyphenol‐rich Pomegranate Fruit Extract Suppresses NF‐κB and IL‐6 Expression by Blocking the Activation of IKKβ and NIK in Primary Human Chondrocytes

A. Haseeb, T. Haqqi, N. Khan, 2017, Phytotherapy research : PTR.

Nrf2/ARE pathway attenuates oxidative and apoptotic response in human osteoarthritis chondrocytes by activating ERK1/2/ELK1-P70S6K-P90RSK signaling axis.

I. Ahmad, T. Haqqi, N. Khan, 2018, Free radical biology & medicine.

Bilirubin augments radiation injury and leads to increased infection and mortality in mice: molecular mechanisms.

N. Khan, T. Poduval, 2012, Free radical biology & medicine.

Autophagy plays an essential role in bone homeostasis

F. Safadi, N. Khan, M. Ansari, 2019, Journal of cellular physiology.

Network Analysis Identifies Gene Regulatory Network Indicating the Role of RUNX1 in Human Intervertebral Disc Degeneration

H. Drissi, N. Khan, S. Presciutti, 2020, Genes.

Dataset of effect of Wogonin, a natural flavonoid, on the viability and activation of NF-κB and MAPKs in IL-1β-stimulated human OA chondrocytes

Pratap Devarapalli, A. Haseeb, T. Haqqi, 2017, Data in brief.

Deep sequencing and analyses of miRNAs, isomiRs and miRNA induced silencing complex (miRISC)-associated miRNome in primary human chondrocytes

I. Ahmad, M. Makki, A. Haseeb, 2017, Scientific Reports.

Pleiotropic Roles of Nrf2 as Regulators of Chondrocyte Apoptosis, Oxidative Stress, Inflammatory Response and Catabolic and Anabolic Pathways in Osteoarthritis

T. Haqqi, N. Khan, 2017 .