A. Schotte

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Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamine and [3H]alniditan.

J. Leysen, G. Haegeman, I. van de Weyer, 1996, Molecular pharmacology.

Survey on the pharmacodynamics of the new antipsychotic risperidone

J. Leysen, A. Megens, T. Meert, 1994, Psychopharmacology.

Different Subcellular Localization of Neurotensin‐Receptor and Neurotensin‐Acceptor Sites in the Rat Brain Dopaminergic System

W. Rostène, P. Laduron, A. Schotte, 1988, Journal of neurochemistry.

Evidence for a displaceable non-specific [3H]neurotensin binding site in rat brain

J. Leysen, P. Laduron, A. Schotte, 1986, Naunyn-Schmiedeberg's Archives of Pharmacology.

Two populations of neurotensin binding sites in murine brain: discrimination by the antihistamine levocabastine reveals markedly different radioautographic distribution.

W. Rostène, P. Kitabgi, P. Laduron, 1987, European journal of pharmacology.

Autoradiographic evidence for the localization of high affinity neurotensin binding sites on dopaminergic nerve terminals in the nigrostriatal and mesolimbic pathways in rat brain.

J. Leysen, A. Schotte, 1989, Journal of chemical neuroanatomy.

6.2 Role and localization of serotonin-5HT2 receptors

J. Leysen, A. Schotte, 1992 .

Impact of Janssen drugs for the identification of brain receptors

J. Leysen, P. Laduron, J. van Dun, 1986 .

Solubilized serotonin receptors from rat and dog brain

B. Ilien, P. Laduron, A. Schotte, 1982, FEBS letters.

Endogenous dopamine limits the binding of antipsychotic drugs to D3 receptors in the rat brain: a quantitative autoradiographic study

P. Bonaventure, J. Leysen, A. Schotte, 1996, The Histochemical Journal.

Autoradiographic evidence for the occlusion of rat brain dopamine D3 receptors in vivo.

J. Leysen, W. Luyten, W. Gommeren, 1992, European journal of pharmacology.

Efficacy and Safety of Paliperidone Palmitate 3-Month Formulation for Patients with Schizophrenia: A Randomized, Multicenter, Double-Blind, Noninferiority Study

W. Fleischhacker, S. Gopal, A. Savitz, 2016, The international journal of neuropsychopharmacology.

Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding

P. F. M. Janssen, J. Leysen, W. Luyten, 1996, Psychopharmacology.

Identification of 5-HT2 receptors, alpha 1-adrenoceptors and amine release sites in rat brain by autoradiography with [125I]7-amino-8-iodo-ketanserin.

J. Leysen, A. Schotte, 1989, European journal of pharmacology.

In vitro receptor binding and in vivo receptor occupancy in rat and guinea pig brain: risperidone compared with antipsychotics hitherto used.

P. Bonaventure, J. Leysen, A. Schotte, 1995, Japanese journal of pharmacology.

Efficacy and Safety of the 3-Month Formulation of Paliperidone Palmitate vs Placebo for Relapse Prevention of Schizophrenia: A Randomized Clinical Trial.

Yanning Liu, S. Gopal, B. Remmerie, 2015, JAMA psychiatry.

Different postnatal ontogeny of two [3H]neurotensin binding sites in rat brain

P. Laduron, A. Schotte, 1987, Brain Research.

Interaction of antipsychotic drugs with neurotransmitter receptor sites in vitro and in vivo in relation to pharmacological and clinical effects: role of 5HT2 receptors

J. Leysen, A. Megens, W. Luyten, 2005, Psychopharmacology.

Occupancy of central neurotransmitter receptors by risperidone, clozapine and haloperidol, measured ex vivo by quantitative autoradiography

J. Leysen, A. Megens, A. Schotte, 1993, Brain Research.

Risperidone: a novel antipsychotic with balanced serotonin-dopamine antagonism, receptor occupancy profile, and pharmacologic activity.

J. Leysen, A. Megens, P. Janssen, 1994, The Journal of clinical psychiatry.

Abstracts of papers and posters Meeting on Pharmaceutical Sciences

S. W. F. Omta, Gert Luurtsema, John Urquhart, 1993, Pharmacy World and Science.

Further characterization of neurotensin binding in the rat brain: levocabastine-displaceable neurotensin binding sites are not histamine-H1 receptors.

J. Leysen, A. Schotte, 1989, Biochemical pharmacology.

Autoradiographic mapping of 5-HT1B- and 5-HT1D receptors in human brain using [3H]alniditan, a new radioligand.

A Schotte, P. Bonaventure, J. Leysen, 1997, Receptors & channels.

Characterization and regional distribution of serotonin S2-receptors in human brain

J. Maloteaux, P. Laduron, A. Schotte, 1983, Brain Research.

Receptor occupancy by ritanserin and risperidone measured using ex vivo autaradiography

J. Leysen, A. Schotte, P. Janssen, 1989, Brain Research.

A Randomized, Double-Blind, Multicenter, Noninferiority Study Comparing Paliperidone Palmitate 6-Month Versus the 3-Month Long-Acting Injectable in Patients With Schizophrenia

S. Galderisi, S. Gopal, P. Lim, 2021, The international journal of neuropsychopharmacology.

P.0533 Paliperidone palmitate 6-month long-acting injectable for schizophrenia: A randomised, double-blind, multicenter, noninferiority phase 3 study

S. Galderisi, S. Gopal, P. Lim, 2021, European Neuropsychopharmacology.

Detailed mapping of serotonin 5-HT1B and 5-HT1D receptor messenger RNA and ligand binding sites in guinea-pig brain and trigeminal ganglion: clues for function

P. Bonaventure, M. Jurzak, J. Leysen, 1997, Neuroscience.

Effects of risperidone and haloperidol on tachykinin and opioid precursor peptide mRNA levels in the caudate‐putamen and nucleus accumbens of the rat

P. Voorn, A. Schotte, G. Docter, 1998, Synapse.

Distinct autoradiographic labelling of serotonin 5-HT2 receptors, alpha 1-adrenoceptors and histamine-H1 receptors and of tetrabenazine-displaceable ketanserin binding sites in rodent brain with [125I]7-amino-8-iodo-ketanserin.

J. Leysen, A. Schotte, 1988, European journal of pharmacology.

Dopamine D2 receptor occupancy by risperidone: Implications for the timing and magnitude of clinical response

V. Pérez, E. Alvarez, I. Carrió, 2006, Psychiatry Research: Neuroimaging.

Solubilization of serotonin S2-receptors from human brain.

J. Maloteaux, P. Laduron, A. Schotte, 1984, European journal of pharmacology.

Striatal dopamine receptors in rats displaying long‐term behavioural sensitization to morphine

J. Leysen, L. Vanderschuren, A. Schoffelmeer, 1997, Synapse.

Evidence For Two Neurochemical Divisions in the Human Nucleus Accumbens

H. Berendse, E. Richfield, P. Voorn, 1994, The European journal of neuroscience.

[3H]Desipramine and [3H]imipramine binding are not associated with noradrenaline and serotonin uptake in the brain.

P. Laduron, A. Schotte, M. Robbyns, 1982, European journal of pharmacology.

FURTHER CHARACTERIZATION OF TWO 3H-NEUROTENSIN BINDING SITES IN RAT BRAIN

P. Laduron, A. Schotte, 1987 .