P. Escobar

发表

Coupling cytotoxicity biomarkers with DNA damage assessment in TK6 human lymphoblast cells.

Jing Shi, S. Springer, P. Escobar, 2010, Mutation research.

Use of the bacterial reverse mutation assay to predict carcinogenicity of N-nitrosamines.

K. Cross, A. Czich, A. Lynch, 2022, Regulatory toxicology and pharmacology : RTP.

Analysis of historical negative control group data from the rat in vivo micronucleus assay.

S. Dertinger, M. Fellows, D. Lovell, 2020, Mutation research.

In Vivo Mutagenicity Testing of Arylboronic Acids and Esters

Krista L Dobo, S. Galloway, R. Jolly, 2019, Environmental and molecular mutagenesis.

Nonclinical safety assessment of epigenetic modulatory drugs: Current status and industry perspective.

Matthew M. Abernathy, K. Kolaja, L. Aschenbrenner, 2020, Regulatory toxicology and pharmacology : RTP.

New and emerging technologies for genetic toxicity testing

Jiri Aubrecht, Robert H Schiestl, James F Rusling, 2011, Environmental and molecular mutagenesis.

Fourth International Workgroup on Genotoxicity testing: results of the in vivo Comet assay workgroup.

Raymond R Tice, Masamitsu Honma, Yoshifumi Uno, 2007, Mutation research.

Bacterial mutagenicity screening in the pharmaceutical industry.

R. Snyder, B. Mahadevan, S. Sawant, 2013, Mutation research.

JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for detection of genotoxic carcinogens: II. Summary of definitive validation study results.

Raymond R Tice, Raffaella Corvi, Hajime Kojima, 2015, Mutation research. Genetic toxicology and environmental mutagenesis.

Application of the adverse outcome pathway framework to genotoxic modes of action

A. Fornace, A. Elhajouji, C. Yauk, 2019, Environmental and molecular mutagenesis.

New and Emerging Genetic Toxicity Tests and Approaches to Genetic Toxicology Testing

S. Dertinger, R. Heflich, P. Escobar, 2015 .

Critical issues with the in vivo comet assay: A report of the comet assay working group in the 6th International Workshop on Genotoxicity Testing (IWGT).

Hajime Kojima, Peter Kasper, Yoshifumi Uno, 2015, Mutation research. Genetic toxicology and environmental mutagenesis.

A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals.

M. LeBaron, K. Witt, M. Aardema, 2019, Mutation research. Genetic toxicology and environmental mutagenesis.

Predictions of genotoxic potential, mode of action, molecular targets, and potency via a tiered multiflow® assay data analysis strategy

Stephen D Dertinger, George E Johnson, Patricia A Escobar, 2019, Environmental and molecular mutagenesis.

A Predominant Oxidative Renal Metabolite of Empagliflozin in Male Mice Is Cytotoxic in Mouse Renal Tubular Cells but not Genotoxic

W. Loging, M. Taub, H. Maw, 2017, International journal of toxicology.

Are all bacterial strains required by OECD mutagenicity test guideline TG471 needed?

Leon F. Stankowski, Errol Zeiger, Jonathan Howe, 2019, Mutation research.

Revisiting the bacterial mutagenicity assays: Report by a workgroup of the International Workshops on Genotoxicity Testing (IWGT).

E. Zeiger, K. Cross, R. Williams, 2020, Mutation research.

Demonstrating laboratory proficiency in bacterial mutagenicity assays for regulatory submission.

Martha M. Moore, Masayuki Kato, Rosalie K. Elespuru, 2019, Mutation research.

Errol Zeiger, Masayuki Kato, Dan D Levy, 2019, Mutation research.

JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for the detection of genotoxic carcinogens: I. Summary of pre-validation study results.

Raymond R Tice, Raffaella Corvi, Hajime Kojima, 2015, Mutation research. Genetic toxicology and environmental mutagenesis.

A Collaborative Initiative to Establish Genomic Biomarkers for Assessing Tumorigenic Potential to Reduce Reliance on Conventional Rodent Carcinogenicity Studies

Kamin J. Johnson, A. Podtelezhnikov, J. Corton, 2022, Toxicological sciences : an official journal of the Society of Toxicology.

Error-corrected next-generation sequencing to advance nonclinical genotoxicity and carcinogenicity testing

K. Witt, C. Yauk, F. Marchetti, 2023, Nature Reviews Drug Discovery.

Error-corrected Next Generation Sequencing - Promises and Challenges for Genotoxicity and Cancer Risk Assessment.

K. Witt, F. Marchetti, Sheroy Minocherhomji, 2023, Mutation research. Reviews in mutation research.

Next Generation Sequencing Workshop at the Royal Society of Medicine (London, May 2022): How genomics is on the path to modernizing Genetic Toxicology.

I. Martincorena, K. Witt, J. Kucab, 2023, Mutagenesis.

Comparison of the transgenic rodent mutation assay, error corrected next generation duplex sequencing, and the alkaline comet assay to detect dose-related mutations following exposure to N-nitrosodiethylamine.

Shaofei Zhang, J. Bercu, M. Schuler, 2023, Mutation research. Genetic toxicology and environmental mutagenesis.

A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals.

M. LeBaron, K. Witt, M. Aardema, 2019, Mutation research. Genetic toxicology and environmental mutagenesis.