G. Willemsens

发表

The Novel Azole R126638 Is a Selective Inhibitor of Ergosterol Synthesis in Candida albicans, Trichophyton spp., and Microsporum canis

L. Meerpoel, J. Ausma, F. Odds, 2004, Antimicrobial Agents and Chemotherapy.

Biochemical Approaches to Selective Antifungal Activity. Focus on Azole Antifungals

P. Janssen, H. Moereels, P. Marichal, 1989, Mycoses.

Perturbation of sterol biosynthesis by itraconazole and ketoconazole in Leishmania mexicana mexicana infected macrophages.

F. Opperdoes, D. Hart, H. Vanden Bossche, 1989, Molecular and biochemical parasitology.

The action of miconazole of the growth of Candida albicans.

H. van den Bossche, J. V. van Cutsem, G. Willemsens, 1975, Sabouraudia.

In vitro and in vivo effects of the antimycotic drug ketoconazole on sterol synthesis

H. van den Bossche, J. V. van Cutsem, H. Bossche, 1980, Antimicrobial Agents and Chemotherapy.

Molecular basis for the antimycotic and antibacterial activity of N‐substituted imidazoles and triazoles: The inhibition of isoprenoid biosynthesis

P. Marichal, H. Bossche, W. Lauwers, 1984 .

Effects of etomidate on steroid biosynthesis in subcellular fractions of bovine adrenals.

D. Bellens, H. Bossche, H. Vanden Bossche, 1984, Biochemical pharmacology.

Cytochrome p‐450: Target for itraconazole

P. Marichal, H. Vanden Bossche, R. De Coster, 1986 .

Ridogrel: a selective inhibitor of the cytochrome P450-dependent thromboxane synthesis.

P. Janssen, D. Bellens, H. Vanden Bossche, 1992, Biochemical pharmacology.

High-content assays for evaluating cellular and hepatic diacylglycerol acyltransferase activity

M. Connelly, J. Linders, Charles D Smith, 2010, Journal of Lipid Research.

Anti-Candida drugs--the biochemical basis for their activity.

P. Marichal, H. Bossche, H. Vanden Bossche, 1987, Critical reviews in microbiology.

R 76713 and enantiomers: selective, nonsteroidal inhibitors of the cytochrome P450-dependent oestrogen synthesis.

P. Janssen, H. Moereels, D. Bellens, 1990, Biochemical pharmacology.

Cytochrome P450-Dependent 14α-Demethylase: Target for Antifungal Agents and Herbicides

P. Marichal, H. Bossche, H. Verhoeven, 1992 .

Retinoic Acid and Cytochrome P-450

H. Bossche, G. Willemsens, 1991 .

Inhibition of all-TRANS-retinoic acid metabolism by R116010 induces antitumour activity

M. Janicot, L. Dillen, J. van Dun, 2002, British Journal of Cancer.

TRICYCLIC LACTAM DERIVATIVES AS 11-BETA HYDROXYSTEROD DEHYDROGENASE INHIBITORS

G. Willemsens, T. Linders, 2017 .

R115866 inhibits all-trans-retinoic acid metabolism and exerts retinoidal effects in rodents.

L. Dillen, P. Borghgraef, H. Szel, 2000, The Journal of pharmacology and experimental therapeutics.

Hypothesis on the molecular basis of the antifungal activity of N-substituted imidazoles and triazoles.

H. van den Bossche, P. Marichal, H. Bossche, 1983, Biochemical Society transactions.

Saperconazole: A selective inhibitor of the cytochrome P‐450‐dependent ergosterol synthesis in Candida albicans, Aspergillus fumigatus and Trichophyton mentagrophytes

P A Janssen, P. Marichal, D. Bellens, 1990, Mycoses.

Synthesis and in vitro and in vivo Antifungal Activity of the Hydroxy Metabolites of Saperconazole

J. Heeres, M. Oris, L. Meerpoel, 2010, ChemMedChem.

Biochemical effects of miconazole on fungi. II. Inhibition of ergosterol biosynthesis in Candida albicans.

H. van den Bossche, W. Lauwers, G. Willemsens, 1978, Chemico-biological interactions.

Synthesis and in vitro and in vivo structure-activity relationships of novel antifungal triazoles for dermatology.

J. Heeres, M. Oris, L. Meerpoel, 2005, Journal of medicinal chemistry.

The interaction of miconazole and ketoconazole with lipids.

H. van den Bossche, J. V. van Cutsem, P. Marichal, 1982, Biochemical pharmacology.

Inhibition of ergosterol synthesis in Candida albicans by ketoconazole [proceedings].

H. van den Bossche, G. Willemsens, W. Cools, 1979, Archives Internationales de Physiologie et de Biochimie.

R 75251, a new inhibitor of steroid biosynthesis

P. Janssen, E. Snoeck, A. Raeymaekers, 1990, The Prostate.

Cytochrome-P-450-dependent metabolism of retinoic acid in rat skin microsomes: inhibition by ketoconazole.

P. Janssen, H. Vanden Bossche, G. Willemsens, 1988, Skin pharmacology : the official journal of the Skin Pharmacology Society.

From 14 alpha-demethylase inhibitors in fungal cells to androgen and oestrogen biosynthesis inhibitors in mammalian cells.

P. Janssen, P A Janssen, D. Bellens, 1990, Biochemical Society transactions.

Endocrinological effects of single daily ketoconazole administration in male beagle dogs.

R. De Coster, G. Willemsens, D. Beerens, 1984, Acta endocrinologica.

Identification of 17α, 20α‐dihydroxyprogesterone in testicular extracts after incubation with ketoconazole

H. Bossche, W. Lauwers, G. Willemsens, 1985 .

Ketoconazole an inhibitor of the cytochrome P-450 dependent testosterone biosynthesis.

H. Vanden Bossche, W. Lauwers, G. Willemsens, 1985, Progress in clinical and biological research.

Synthesis and in vitro and in vivo Antifungal Activity of the Hydroxy Metabolites of Saperconazole

J. Heeres, M. Oris, L. Meerpoel, 2010, ChemMedChem.