P. Watson

发表

Lanosterol to Ergosterol — Enzymology, Inhibition and Genetics

D. Kelly, S. Kelly, I. Stansfield, 1990 .

Analysis of the T Cell Receptor Vα Repertoire in Hashimoto’s Thyroiditis: Evidence for the Restricted Accumulation of CD8+ T Cells in the Absence of CD4+ T Cell Restriction1

A. Weetman, R. Mcintosh, P. Watson, 1997 .

Somatic hypermutation in autoimmune thyroid disease.

A. Weetman, R. Mcintosh, P. Watson, 1998, Immunological reviews.

Somatic hypermutation in antoimmune thyroid disease

A. Weetman, P. Watson, R. Mclntosh, 1998 .

Demonstration of immunoglobulin G, A, and E autoantibodies to the human thyrotropin receptor using flow cytometry.

M. Ludgate, M. Wiltshire, A. Weetman, 2002, The Journal of clinical endocrinology and metabolism.

Immunoglobulin Gκ Antithyroid Peroxidase Antibodies in Hashimoto’s Thyroiditis: Epitope-Mapping Analysis1

B. Czarnocka, A. Weetman, P. Carayon, 1997 .

An insertion/deletion polymorphism in the gene encoding angiotensin converting enzyme is not associated with generalised vitiligo in an English population

D. Gawkrodger, N. Gavalas, A. Weetman, 2005, Archives of Dermatological Research.

Low frequency of pendrin autoantibodies detected using a radioligand binding assay in patients with autoimmune thyroid disease.

A. Weetman, H. Sandhu, E. Kemp, 2013, The Journal of clinical endocrinology and metabolism.

Cytokines and thyroid function.

R. Ajjan, A. Weetman, P. Watson, 1996, Advances in neuroimmunology.

No association between a thyrotropin receptor gene polymorphism and Graves' disease in the female population.

K. Kotsa, A. Weetman, P. Watson, 1997, Thyroid : official journal of the American Thyroid Association.

Association of Graves' disease with an allele of the interleukin-1 receptor antagonist gene.

A. Blakemore, G. Duff, A. Weetman, 1995, The Journal of clinical endocrinology and metabolism.

Analysis of allelic variants in the catalase gene in patients with the skin depigmenting disorder vitiligo.

D. Gawkrodger, N. Gavalas, A. Weetman, 2006, Biochemical and biophysical research communications.

A study of the association between a polymorphism in the CTLA‐4 gene and postpartum thyroiditis

A. Weetman, E. Waterman, J. Lazarus, 1998, Clinical endocrinology.

Cytokines in Graves’ Disease

R. Ajjan, A. Weetman, P. Watson, 2000 .

Cytokines and Graves' disease.

R. Ajjan, A. Weetman, P. Watson, 1997, Bailliere's clinical endocrinology and metabolism.

Genetic and physiological analysis of azole sensitivity in Saccharomyces cerevisiae.

S. Kelly, H. Bligh, S. Kenna, 1989, Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology.

Detection and localization of chemokine gene expression in autoimmune thyroid disease

A. Weetman, M. Woodroofe, E. Kemp, 2003, Clinical endocrinology.

Apoptosis and caspase-3 in experimental anti-glomerular basement membrane nephritis.

B. Yang, B. Wagner, T. Johnson, 2001, Journal of the American Society of Nephrology : JASN.

Intrathyroidal cytokine gene expression in Hashimoto's thyroiditis

R. Ajjan, A. Weetman, R. Mcintosh, 1996, Clinical and experimental immunology.

No restriction of intrathyroidal T cell receptor Vα families in the thyroid of Graves’disease

A. Weetman, R. Mcintosh, P. Watson, 1993 .

Effects of caspase inhibition on the progression of experimental glomerulonephritis.

Bin Yang, A. E. El Nahas, B. Wagner, 2003, Kidney international.

Isolation and analysis of ketoconazole resistant mutants of Saccharomyces cerevisiae.

S. Kelly, P. Watson, M. Rose, 1988, Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology.

Activating autoantibodies against the calcium-sensing receptor detected in two patients with autoimmune polyendocrine syndrome type 1.

E. Brown, N. Gavalas, A. Weetman, 2009, The Journal of clinical endocrinology and metabolism.

High-dose growth hormone does not affect proinflammatory cytokine (tumor necrosis factor-alpha, interleukin-6, and interferon-gamma) release from activated peripheral blood mononuclear cells or after minimal to moderate surgical stress.

A. Revhaug, R. Ross, A. Weetman, 2000, The Journal of clinical endocrinology and metabolism.

The calcium-sensing receptor is a target of autoantibodies in patients with autoimmune polyendocrine syndrome type 1.

E. Brown, N. Gavalas, A. Weetman, 2007, The Journal of clinical endocrinology and metabolism.

Function-blocking autoantibodies to the melanin-concentrating hormone receptor in vitiligo patients

J. Haycock, D. Gawkrodger, N. Gavalas, 2006, Laboratory Investigation.

Autoantibodies in vitiligo patients are not directed to the melanocyte differentiation antigen MelanA/MART1

D. Gawkrodger, P. Watson, A. Weetman, 2002, Clinical and experimental immunology.

Caspase-3 and apoptosis in experimental chronic renal scarring.

B. Yang, A. E. El Nahas, B. Wagner, 2001, Kidney international.

Effects of Transforming Growth Factor-β1 on Renal Extracellular Matrix Components and Their Regulating Proteins

A. E. El Nahas, T. Johnson, J. Douthwaite, 1999 .

Detection of IL-12, IL-13, and IL-15 messenger ribonucleic acid in the thyroid of patients with autoimmune thyroid disease.

R. Ajjan, A. Weetman, P. Watson, 1997, The Journal of clinical endocrinology and metabolism.

T cell receptor β chain gene polymorphisms in Graves' disease

A. Weetman, P. Watson, N. Tandon, 1993 .

Defective sterol C5-6 desaturation and azole resistance: a new hypothesis for the mode of action of azole antifungals.

S. Kelly, S. Ellis, P. Watson, 1989, Biochemical and biophysical research communications.

Analysis of cytokine gene expression in Graves' disease and multinodular goiter.

A. Weetman, P. Watson, A. Pickerill, 1994, The Journal of clinical endocrinology and metabolism.

Cloning and analysis of IgG kappa and IgG lambda anti-thyroglobulin autoantibodies from a patient with Hashimoto's thyroiditis: evidence for in vivo antigen-driven repertoire selection.

A. Weetman, E. Kemp, R. Mcintosh, 1996, Journal of immunology.

Contrasting activities of thyrotropin receptor antibodies in experimental models of Graves' disease induced by injection of transfected fibroblasts or deoxyribonucleic acid vaccination.

J. Banga, A. Weetman, P. Watson, 2003, Endocrinology.

Transglutaminase 2: Development of therapeutic antibodies reveals four inhibitory epitopes and confirms extracellular function in fibrotic remodelling

Hélène Bon, C. Kettleborough, K. Cain, 2021, British journal of pharmacology.

Interplay between transglutaminases and heparan sulphate in progressive renal scarring

M. Vinciguerra, T. Johnson, H. Lortat-Jacob, 2016, Scientific Reports.

The pattern of cytokine mRNA expression in ovarian endometriomata.

I. Cooke, R. Ajjan, A. Weetman, 1997, Molecular human reproduction.

Immunoglobulin G kappa antithyroid peroxidase antibodies in Hashimoto's thyroiditis: epitope-mapping analysis.

B. Czarnocka, A. Weetman, P. Carayon, 1997, The Journal of clinical endocrinology and metabolism.

Detection and location of the enzymes of de novo pyrimidine biosynthesis in mammalian spermatozoa.

Dylan M Glubb, J. Lucocq, M. Löffler, 2002, Reproduction.

Induction of hyperthyroidism in mice by intradermal immunization with DNA encoding the thyrotropin receptor

J. Banga, K. Barrett, A. Weetman, 2004, Clinical and experimental immunology.

Immunoprecipitation of melanogenic enzyme autoantigens with vitiligo sera: evidence for cross‐reactive autoantibodies to tyrosinase and tyrosinase‐related protein‐2 (TRP‐2)

D. Gawkrodger, A. Weetman, E. Kemp, 1997, Clinical and experimental immunology.

Lack of association between a polymorphism in the coding region of the thyrotropin receptor gene and Graves' disease.

A. Weetman, R. Mcintosh, P. Watson, 1995, The Journal of clinical endocrinology and metabolism.

ANALYSIS OF THE T-CELL RECEPTOR V a REPERTOIRE AND CYTOKINE GENE EXPRESSION IN SJÖGREN ’ S SYNDROME

R. Ajjan, A. Weetman, E. Waterman, 1998 .

Mapping of melanin‐concentrating hormone receptor 1 B cell epitopes predicts two major binding sites for vitiligo patient autoantibodies

D. Gawkrodger, N. Gavalas, A. Weetman, 2009, Experimental dermatology.

Analysis of immunoglobulin G kappa antithyroid peroxidase antibodies from different tissues in Hashimoto's thyroiditis.

J. Banga, A. Weetman, A. Gardas, 1997, The Journal of clinical endocrinology and metabolism.

Key residues contributing to dominant conformational autoantigenic epitopes on thyroid peroxidase identified by mutagenesis.

J. Banga, B. Sutton, A. Weetman, 2004, Biochemical and biophysical research communications.

Molecular genetic studies on the mode of action of azole antifungal agents.

S. Kelly, J. Rowe, P. Watson, 1991, Biochemical Society transactions.

Detection of tyrosinase autoantibodies in patients with vitiligo using 35S-labeled recombinant human tyrosinase in a radioimmunoassay.

D. Gawkrodger, S. Macneil, A. Weetman, 1997, The Journal of investigative dermatology.

Autoantibodies against tyrosine hydroxylase in patients with non‐segmental (generalised) vitiligo

D. Gawkrodger, A. Weetman, E. Kemp, 2011, Experimental dermatology.

Autoantigens in vitiligo identified by the serological selection of a phage-displayed melanocyte cDNA expression library.

D. Gawkrodger, A. Weetman, E. Waterman, 2010, The Journal of investigative dermatology.

The melanin-concentrating hormone receptor 1, a novel target of autoantibody responses in vitiligo.

B. Hawes, K. O'neill, D. Gawkrodger, 2002, The Journal of clinical investigation.

Autoantibodies in vitiligo patients recognize multiple domains of the melanin-concentrating hormone receptor.

D. Gawkrodger, A. Weetman, E. Waterman, 2003, The Journal of investigative dermatology.

A single-nucleotide polymorphism in the gene encoding lymphoid protein tyrosine phosphatase (PTPN22) confers susceptibility to generalised vitiligo

D. Gawkrodger, I. Cantón, N. Gavalas, 2005, Genes and Immunity.

Identification of epitopes on tyrosinase which are recognized by autoantibodies from patients with vitiligo.

D. Gawkrodger, A. Weetman, E. Waterman, 1999, The Journal of investigative dermatology.

Molecular mapping of epitopes on melanocyte‐specific protein Pmel17 which are recognized by autoantibodies in patients with vitiligo

D. Gawkrodger, A. Weetman, E. Waterman, 2001, Clinical and Experimental Immunology.

The Journal of Clinical Endocrinology & Metabolism Printed in U.S.A. Copyright © 2000 by The Endocrine Society Detection of Binding and Blocking Autoantibodies to the Human Sodium-Iodide Symporter in Patients with

T. Endo, R. Ajjan, A. Weetman, 2022 .

A Crucial Sequence for Transglutaminase Type 2 Extracellular Trafficking in Renal Tubular Epithelial Cells Lies in Its N-terminal β-Sandwich Domain

A. Streets, Linghong Huang, T. Johnson, 2011, The Journal of Biological Chemistry.

Mutations of the PDS gene, encoding pendrin, are associated with protein mislocalization and loss of iodide efflux: implications for thyroid dysfunction in Pendred syndrome.

Richard C Trembath, R. Trembath, A. Weetman, 2002, The Journal of clinical endocrinology and metabolism.

The modulation of the human sodium iodide symporter activity by Graves' disease sera.

M. Ludgate, R. Ajjan, A. Weetman, 1998, The Journal of clinical endocrinology and metabolism.

Semi-quantitative analysis of interleukin-1 alpha, interleukin-6 and interleukin-8 mRNA expression by human thyrocytes.

A. Weetman, P. Watson, A. Pickerill, 1995, Journal of molecular endocrinology.

Expression of apoptosis-related genes and proteins in experimental chronic renal scarring.

B. Yang, A. E. El Nahas, B. Wagner, 2001, Journal of the American Society of Nephrology : JASN.

A shift in the Bax/Bcl-2 balance may activate caspase-3 and modulate apoptosis in experimental glomerulonephritis.

Bin Yang, A. E. El Nahas, B. Wagner, 2002, Kidney international.

Regulation and tissue distribution of the human sodium iodide symporter gene

M. Ludgate, R. Ajjan, A. Weetman, 1998, Clinical endocrinology.

Mapping of Human Autoantibody Binding Sites on the Calcium-Sensing Receptor

E. Brown, J. C. Pallais, N. Gavalas, 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Association of HLA‐DQA1*0501 with Graves’ disease in English Caucasian men and women

A. Weetman, P. Watson, N. Wheatcroft, 1996, Clinical endocrinology.

Treatment of Graves' disease with the block-replace regimen of antithyroid drugs: the effect of treatment duration and immunogenetic susceptibility on relapse.

V. Chatterjee, O. M. Edwards, A. Weetman, 1994, The Quarterly journal of medicine.

Is there loss or qualitative changes in the expression of thyroid peroxidase protein in thyroid epithelial cancer?

E. Gubała, B. Jarzab, B. Czarnocka, 2001, British Journal of Cancer.

The sodium iodide symporter gene and its regulation by cytokines found in autoimmunity.

M. Ludgate, R. Ajjan, A. Weetman, 1998, The Journal of endocrinology.

IL‐14 and IL‐16 are expressed in the thyroid of patients with either Graves’ disease or Hashimoto's thyroiditis

R. Ajjan, A. Weetman, E. Helen Kemp, 2015, Clinical endocrinology.

Human thyroid peroxidase: mapping of autoantibodies, conformational epitopes to the enzyme surface

J. Banga, B. Sutton, A. Weetman, 2000, Redox report : communications in free radical research.

Evaluation of conformational epitopes on thyroid peroxidase by antipeptide antibody binding and mutagenesis

J. Banga, B. Sutton, A. Weetman, 2004, Clinical and experimental immunology.

Proposed PBPK Model to Predict Infant Exposure to Toxic Chemicals in Breast Milk

R. Ajjan, Ge Dai, P. Watson, 2002 .

Catalytic activities of human debrisoquine 4-hydroxylase cytochrome P450 (CYP2D6) expressed in yeast.

G. Tucker, M. S. Ching, M. Lennard, 1992, Biochemical pharmacology.

HLA-G does not have a pathophysiological role in Graves’ disease

A. Weetman, E. Kemp, P. Watson, 2003, Journal of Clinical Pathology.

Identification of antigenic domains on the human sodium‐iodide symporter which are recognized by autoantibodies from patients with autoimmune thyroid disease

M. Ludgate, R. Ajjan, A. Weetman, 2001, Clinical and experimental immunology.

A CTLA‐4 gene polymorphism is associated with both Graves' disease and autoimmune hypothyroidism

K. Kotsa, P. Watson, A. Weetman, 1997, Clinical endocrinology.

Modelling the Economics of Type 2 Diabetes Mellitus Prevention: A Literature Review of Methods

L. Preston, A. Brennan, H. Squires, 2014, Applied Health Economics and Health Policy.

Comparative mapping of cloned human and murine antithyroglobulin antibodies: recognition by human antibodies of an immunodominant region.

A. Weetman, P. Carayon, J. Ruf, 1998, Thyroid : official journal of the American Thyroid Association.

The sodium iodide symporter gene and its regulation by cytokines found in autoimmunity.

R. Ajjan, A. Weetman, M. Crisp, 1998, Journal of Endocrinology.

Analysis of the T cell receptor V alpha repertoire in Hashimoto's thyroiditis: evidence for the restricted accumulation of CD8+ T cells in the absence of CD4+ T cell restriction.

A. Weetman, R. Mcintosh, P. Watson, 1997, The Journal of clinical endocrinology and metabolism.