A. Koch

发表

THOC5, a member of the mRNA export complex: a novel link between mRNA export machinery and signal transduction pathways in cell proliferation and differentiation

T. Tamura, D. Tran, A. Koch, 2014, Cell Communication and Signaling.

THOC5, a member of the mRNA export complex, contributes to processing of a subset of wingless/integrated (Wnt) target mRNAs and integrity of the gut epithelial barrier

R. Klopfleisch, Patricia Moran-Losada, T. Tamura, 2013, BMC Cell Biology.

The SH2-domian-containing inositol 5-phosphatase (SHIP)-2 binds to c-Met directly via tyrosine residue 1356 and involves hepatocyte growth factor (HGF)-induced lamellipodium formation, cell scattering and cell spreading

T. Tamura, O. E. Bounkari, A. Koch, 2005, Oncogene.

Tyrosine phosphorylation modulates binding preference to cyclin-dependent kinases and subcellular localization of p27Kip1 in the acute promyelocytic leukemia cell line NB4.

K. Welte, T. Tamura, A. Kardinal, 2006, Blood.

Tyrosine phosphorylation modulates binding preference to cyclin-dependent kinases and subcellular localization of p 27 Kip 1 in the acute promyelocytic leukemia cell line NB 4 Short title : Tyrosine phosphorylation modulates p 27 Kip 1

K. Welte, T. Tamura, A. Kardinal, 2005 .

THOC5 controls 3′end-processing of immediate early genes via interaction with polyadenylation specific factor 100 (CPSF100)

A. Williamson, A. Whetton, O. Dittrich‐Breiholz, 2014, Nucleic acids research.

Nuclear localization of the pre‐mRNA associating protein THOC7 depends upon its direct interaction with Fms tyrosine kinase interacting protein (FMIP)

J. Griffiths, T. Pieler, A. Whetton, 2009, FEBS letters.

The SH2-containing inositol 5-phosphatase (SHIP)-1 is implicated in the control of cell-cell junction and induces dissociation and dispersion of MDCK cells

T. Tamura, A. Koch, A. Mancini, 2002, Oncogene.

Tyrosine phosphatase SHP-2 is a regulator of p27Kip1 tyrosine phosphorylation

M. Schiffer, Dominique T Brandt, D. Brandt, 2008, Cell cycle.

c-Cbl Associates Directly with the C-terminal Tail of the Receptor for the Macrophage Colony-stimulating Factor, c-Fms, and Down-modulates This Receptor but Not the Viral Oncogene v-Fms*

T. Tamura, A. Koch, A. Mancini, 2002, The Journal of Biological Chemistry.

Identification of a second Grb2 binding site in the v-Fms tyrosine kinase

R. Niedenthal, H. Niemann, T. Tamura, 1997, Oncogene.

Myc target gene, long intergenic noncoding RNA, Linc00176 in hepatocellular carcinoma regulates cell cycle and cell survival by titrating tumor suppressor microRNAs

T. Tamura, D. Tran, A. Koch, 2018, Oncogene.

Inhibition of Abl tyrosine kinase enhances nerve growth factor-mediated signaling in Bcr–Abl transformed cells via the alteration of signaling complex and the receptor turnover

T. Tamura, M. Scherr, M. Eder, 2008, Oncogene.

THOC5, a member of the mRNA export complex: a novel link between mRNA export machinery and signal transduction pathways in cell proliferation and differentiation

T. Tamura, D. Tran, A. Koch, 2014, Cell Communication and Signaling.

Transcriptional regulation of immediate-early gene response by THOC5, a member of mRNA export complex, contributes to the M-CSF-induced macrophage differentiation

A. Williamson, A. Whetton, O. Dittrich‐Breiholz, 2013, Cell Death and Disease.

The tyrosine phosphorylated carboxyterminus of the EGF receptor is a binding site for GAP and PLC‐gamma.

T. Pawson, A. Ullrich, Nanxin Li, 1990, The EMBO journal.

Identification of novel target genes of nerve growth factor (NGF) in human mastocytoma cell line (HMC-1 (V560G c-Kit)) by transcriptome analysis

O. Dittrich‐Breiholz, M. Kracht, H. Schneider, 2011, BMC Genomics.

Src Homology 2-containing Inositol 5-Phosphatase 1 Binds to the Multifunctional Docking Site of c-Met and Potentiates Hepatocyte Growth Factor-induced Branching Tubulogenesis*

H. Niemann, T. Tamura, A. Mohr, 2001, The Journal of Biological Chemistry.

The direct association of the multiple PDZ domain containing proteins (MUPP‐1) with the human c‐Kit C‐terminus is regulated by tyrosine kinase activity

H. Niemann, T. Tamura, A. Koch, 2000, FEBS letters.

Direct interaction of nerve growth factor receptor, TrkA, with non‐receptor tyrosine kinase, c‐Abl, through the activation loop

R. Niedenthal, H. Niemann, T. Tamura, 2000, FEBS letters.

FMIP, a novel Fms-interacting protein, affects granulocyte/macrophage differentiation

J. Dumanski, H. Niemann, T. Tamura, 1999, Oncogene.

THOC5/FMIP, an mRNA export TREX complex protein, is essential for hematopoietic primitive cell survival in vivo

Anthony D Whetton, A. Gruber, E. Jaworska, 2010, BMC Biology.

Colony-stimulating factor-1 receptor provides a growth advantage in epithelial cancer cell line A431 in the presence of epidermal growth factor receptor inhibitor gefitinib.

A. Koch, S. E. Niehus, D. D. H. Tran, 2018, Cellular signalling.

Identification of mRNAs that are spliced but not exported to the cytoplasm in the absence of THOC5 in mouse embryo fibroblasts.

T. Tamura, Priyanka Dutta, O. El Bounkari, 2011, RNA.

Murine precision-cut liver slices (PCLS): a new tool for studying tumor microenvironments and cell signaling ex vivo

R. Klopfleisch, T. Tamura, A. Braun, 2014, Cell Communication and Signaling.

Extracellular-signal regulated kinase (Erk1/2), mitogen-activated protein kinase-activated protein kinase 2 (MK2) and tristetraprolin (TTP) comprehensively regulate injury-induced immediate early gene (IEG) response in in vitro liver organ culture.

M. Gaestel, D. Wirth, F. Ewald, 2016, Cellular signalling.

mRNA export protein THOC5 as a tool for identification of target genes for cancer therapy.

T. Tamura, A. Koch, S. Saran, 2016, Cancer letters.

Depletion of three combined THOC5 mRNA export protein target genes synergistically induces human hepatocellular carcinoma cell death

F. Ewald, T. Tamura, B. Nashan, 2016, Oncogene.

The M-CSF receptor substrate and interacting protein FMIP is governed in its subcellular localization by protein kinase C-mediated phosphorylation, and thereby potentiates M-CSF-mediated differentiation

A. Whetton, T. Tamura, A. Koch, 2004, Oncogene.

Treatment with MAPKAP2 (MK2) inhibitor and DNA methylation inhibitor, 5-aza dC, synergistically triggers apoptosis in hepatocellular carcinoma (HCC) via tristetraprolin (TTP).

F. Ewald, T. Tamura, B. Nashan, 2016, Cellular signalling.

Quantification of circadian interactions and protein abundance defines a mechanism for operational stability of the circadian clock

A. Loudon, K. Strimmer, T. House, 2021, bioRxiv.