Daniel J. Hui

发表

of Human Glycosylation Enhanced T Cell Function in a Mouse Model

A. Varki, K. High, M. Jordan, 2013 .

Enhanced T Cell Function in a Mouse Model of Human Glycosylation

E. Wherry, A. Varki, K. High, 2013, The Journal of Immunology.

Overcoming Preexisting Humoral Immunity to AAV Using Capsid Decoys

J. F. Wright, X. Anguela, K. High, 2013, Science Translational Medicine.

Alpha Interferon Induces Distinct Translational Control Programs To Suppress Hepatitis C Virus RNA Replication

M. Gale, R. Sumpter, G. Sen, 2003, Journal of Virology.

Identification of mouse AAV capsid-specific CD8+ T cell epitopes.

H. Ertl, K. High, P. Colosi, 2005, Molecular therapy : the journal of the American Society of Gene Therapy.

Safety of AAV Factor IX Peripheral Transvenular Gene Delivery to Muscle in Hemophilia B Dogs

V. Haurigot, H. Stedman, J. F. Wright, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

Hemophilia B Gene Therapy with a High‐Specific‐Activity Factor IX Variant

J. Rasko, L. Sullivan, X. Anguela, 2017, The New England journal of medicine.

Modulation of tolerance to the transgene product in a nonhuman primate model of AAV-mediated gene transfer to liver.

J. F. Wright, K. High, V. Arruda, 2007, Blood.

Diverse IgG subclass responses to adeno‐associated virus infection and vector administration

K. High, D. Sabatino, F. Mingozzi, 2009, Journal of medical virology.

Modulation of CD8+ T cell responses to AAV vectors with IgG-derived MHC class II epitopes

D. Scott, A. D. De Groot, V. Haurigot, 2013, Molecular therapy : the journal of the American Society of Gene Therapy.

CD8+ T-cell responses to adeno-associated virus capsid in humans

Marcela V Maus, Hildegund C J Ertl, Haiyan Jiang, 2007, Nature Medicine.

Spk-9001: Adeno-Associated Virus Mediated Gene Transfer for Hemophilia B Achieves Sustained Mean Factor IX Activity Levels of >30% without Immunosuppression

L. Sullivan, X. Anguela, M. Carr, 2016 .

A Phase 1/2 Trial of Investigational Spk-8011 in Hemophilia a Demonstrates Durable Expression and Prevention of Bleeds

L. Valentino, X. Anguela, M. Carr, 2018, Blood.

Safety and Efficacy of Subretinal Readministration of a Viral Vector in Large Animals to Treat Congenital Blindness

J. Golden, J. Bennett, K. High, 2010, Science Translational Medicine.

Mouse p56 Blocks a Distinct Function of Eukaryotic Initiation Factor 3 in Translation Initiation*

W. Merrick, G. Sen, F. Terenzi, 2005, Journal of Biological Chemistry.

AAV-1-mediated gene transfer to skeletal muscle in humans results in dose-dependent activation of capsid-specific T cells.

Etiena Basner-Tschakarjan, M. Betts, J. Kastelein, 2009, Blood.

AAV capsid CD8+ T-cell epitopes are highly conserved across AAV serotypes

Etiena Basner-Tschakarjan, H. Ertl, K. High, 2015, Molecular therapy. Methods & clinical development.

Cardiac gene transfer of short hairpin RNA directed against phospholamban effectively knocks down gene expression but causes cellular toxicity in canines.

H. Sweeney, James M. Wilson, G. Gao, 2011, Human gene therapy.

Proteasome inhibitors decrease AAV2 capsid derived peptide epitope presentation on MHC class I following transduction.

K. High, Shangzhen Zhou, F. Mingozzi, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

Capsid antigen presentation flags human hepatocytes for destruction after transduction by adeno-associated viral vectors.

J. Orange, K. High, Shangzhen Zhou, 2009, The Journal of clinical investigation.

Distinct Induction Patterns and Functions of Two Closely Related Interferon-inducible Human Genes, ISG54 and ISG56*

W. Merrick, G. Sen, F. Terenzi, 2006, Journal of Biological Chemistry.

The Mechanism of Protein Synthesis Inhibition by the P56 Family of Viral Stress Inducible Proteins

Daniel J. Hui, 2005 .

A new pathway of translational regulation mediated by eukaryotic initiation factor 3

W. Merrick, G. Sen, Daniel J. Hui, 2000, The EMBO journal.

Replication Suppress Hepatitis C Virus RNA Translational Control Programs To Alpha Interferon Induces Distinct

M. Gale, R. Sumpter, G. Sen, 2003 .

Immunosuppression Modulates Immune Responses to AAV Capsid in Human Subjects Undergoing Intramuscular Gene Transfer for Lipoprotein Lipase Deficiency

D. Gaudet, K. High, F. Mingozzi, 2008 .

AAV-2 Capsid-Specific CD8+ T Cells Limit the Duration of Gene Therapy in Humans and Cross-React with AAV-8 Capsid.

J. Rasko, H. Ertl, K. High, 2006 .

Reversal of blindness in animal models of leber congenital amaurosis using optimized AAV2-mediated gene transfer.

J. F. Wright, G. Acland, C. Zeiss, 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

TmPSMA-02: A CD2 endodomain containing double armored PSMA CAR T with enhanced efficacy and lower immune toxicity.

D. Barrett, W. Gladney, Thomas J. Fountaine, 2022, Journal of Clinical Oncology.

Viral Stress-inducible Protein p56 Inhibits Translation by Blocking the Interaction of eIF3 with the Ternary Complex eIF2·GTP·Met-tRNAi*

W. Merrick, G. Sen, C. Bhasker, 2003, Journal of Biological Chemistry.

Modulation of CD8 Modulation of CD8 ++ T cell responses to AAV vectors with IgG- T cell responses to AAV vectors with IgG-derived MHC class II epitopes derived MHC class II epitopes

V. Haurigot, Shangzhen Zhou, F. Mingozzi, 2022 .

Suppression of CTL Responses against AAV-Capsid Epitopes by Peptide-Induced Regulatory T Cells.

K. High, Shangzhen Zhou, F. Mingozzi, 2009 .

Peptide-Induced Antigen-Specific CD4+CD25+FoxP3+ T Cells Suppress Cytotoxicity T Cell Responses Directed Against the AAV Capsid.

K. High, F. Mingozzi, W. Martin, 2010 .

AAV-1-mediated gene transfer to skeletal muscle in humans results in dose-dependent activation of capsid-specific T cells.

M. Betts, J. Kastelein, K. High, 2009, Blood.

Cardiac gene transfer of short hairpin RNA directed against phospholamban effectively knocks down gene expression but causes cellular toxicity in canines.

H. Sweeney, James M. Wilson, G. Gao, 2011, Human gene therapy.

Spk-8011: Preliminary Results from a Phase 1/2 Dose Escalation Trial of an Investigational AAV-Mediated Gene Therapy for Hemophilia a

X. Anguela, M. Carr, K. High, 2017 .

Safety and Efficacy of Subretinal Readministration of a Viral Vector in Large Animals to Treat Congenital Blindness

J. Golden, J. Bennett, K. High, 2010, Science Translational Medicine.