C. Shelton

发表

Activation and intrinsic γ-secretase activity of presenilin 1

Xulun Zhang, S. Sisodia, Yue-Ming Li, 2010, Proceedings of the National Academy of Sciences.

Stereo-controlled synthesis of novel photoreactive gamma-secretase inhibitors.

O. Ouerfelli, Yue-Ming Li, Y. Yin, 2009, Bioorganic & medicinal chemistry letters.

A Miniaturized 1536-Well Format γ -Secretase Assay

David Shum, Hakim Djaballah, C. Radu, 2009 .

A miniaturized 1536-well format gamma-secretase assay.

David Shum, Hakim Djaballah, C. Radu, 2009, Assay and drug development technologies.

An exo-cell assay for examining real-time γ-secretase activity and inhibition

M. Frattini, Yue-Ming Li, C. Shelton, 2009, Molecular Neurodegeneration.

Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia

B. Cravatt, A. Lichtman, C. Shelton, 2004, Pain.

gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity.

Li-Xuan Qin, D. Notterman, L. Qin, 2009, Cancer research.

Hydrogen peroxide generated extracellularly by receptor-ligand interaction facilitates cell signaling.

D. Golde, C. Shelton, J. Cárcamo, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Reversible Inhibitors of Fatty Acid Amide Hydrolase That Promote Analgesia: Evidence for an Unprecedented Combination of Potency and Selectivity

A. Saghatelian, D. Boger, B. Cravatt, 2004, Journal of Pharmacology and Experimental Therapeutics.

Modulation of γ-secretase specificity using small molecule allosteric inhibitors

Li Yang, Rong Wang, Hakim Djaballah, 2009, Proceedings of the National Academy of Sciences.

Assessment of anandamide's pharmacological effects in mice deficient of both fatty acid amide hydrolase and cannabinoid CB1 receptors.

B. Cravatt, L. Wise, A. Lichtman, 2007, European journal of pharmacology.

Association of Notch signaling pathway expression in liposarcomas with outcome, and targeting with gamma-secretase inhibitors.

L. Qin, S. Singer, R. Maki, 2009, Journal of Clinical Oncology.

gamma-Secretase inhibitors abrogate oxaliplatin-induced activation of the Notch-1 signaling pathway in colon cancer cells resulting in enhanced chemosensitivity.

D. Notterman, L. Qin, G. Schwartz, 2009, Cancer research.

Short communication Assessment of anandamide's pharmacological effects in mice deficient of both fatty acid amide hydrolase and cannabinoid CB 1 receptors

B. Cravatt, L. Wise, A. Lichtman, 2007 .