Frederik Börgel

发表

Synthesis and Pharmacological Evaluation of Fluorinated Quinoxaline‐Based κ‐Opioid Receptor (KOR) Agonists Designed for PET Studies

Samuel T. Slocum, T. Che, B. Wünsch, 2020, ChemMedChem.

Novel σ1 antagonists designed for tumor therapy: Structure - activity relationships of aminoethyl substituted cyclohexanes.

E. Laurini, S. Pricl, H. Humpf, 2020, European journal of medicinal chemistry.

Optimization of the metabolic stability of a fluorinated cannabinoid receptor subtype 2 (CB2) ligand designed for PET studies.

H. de Vries, L. Heitman, B. Wünsch, 2018, European journal of medicinal chemistry.

Synthesis and evaluation of a [18F]BODIPY-labeled caspase-inhibitor.

M. Schäfers, B. Wünsch, S. Hermann, 2017, Bioorganic & Medicinal Chemistry.

Pharmacokinetic properties of enantiomerically pure GluN2B selective NMDA receptor antagonists with 3-benzazepine scaffold.

S. Ametamey, B. Wünsch, D. Schepmann, 2019, Journal of pharmaceutical and biomedical analysis.

Fluorinated GluN2B Receptor Antagonists with a 3‐Benzazepine Scaffold Designed for PET Studies

S. Ametamey, A. Haider, B. Wünsch, 2018, ChemMedChem.

Synthesis, Receptor Affinity, and Antiallodynic Activity of Spirocyclic σ Receptor Ligands with Exocyclic Amino Moiety.

P. Brust, C. Daniliuc, B. Wünsch, 2018, Journal of medicinal chemistry.

Synthesis and Pharmacological Evaluation of Enantiomerically Pure GluN2B Selective NMDA Receptor Antagonists

S. Ametamey, G. Seebohm, N. Strutz‐Seebohm, 2018, ChemMedChem.

Synthesis and biological evaluation of PET tracers designed for imaging of calcium activated potassium channel 3.1 (KCa3.1) channels in vivo

T. Budde, M. Schäfers, A. Schwab, 2021, RSC advances.

Synthesis and Biological Evaluation of Natural-Product-Inspired, Aminoalkyl-Substituted 1-Benzopyrans as Novel Antiplasmodial Agents.

M. Nonato, R. Krauth-Siegel, B. Wünsch, 2021, Journal of medicinal chemistry.

Rigidity versus Flexibility: Is This an Issue in σ1 Receptor Ligand Affinity and Activity?

E. Laurini, M. Fermeglia, S. Pricl, 2016, Journal of medicinal chemistry.

Impact of hydroxy moieties at the benzo[7]annulene ring system of GluN2B ligands: Design, synthesis and biological evaluation.

W. Sippl, C. Daniliuc, B. Wünsch, 2019, Bioorganic & medicinal chemistry.

The Action of Reproductive Fluids and Contained Steroids, Prostaglandins, and Zn2+ on CatSper Ca2+ Channels in Human Sperm

B. Wünsch, M. von Wolff, C. Brenker, 2021, Frontiers in Cell and Developmental Biology.

Structure-Activity Relationship of Purine and Pyrimidine Nucleotides as Ecto-5'-Nucleotidase (CD73) Inhibitors.

K. Jacobson, C. Müller, R. Balasubramanian, 2019, Journal of medicinal chemistry.

Optimization of pharmacokinetic properties by modification of a carbazole-based cannabinoid receptor subtype 2 (CB2) ligand.

H. de Vries, L. Heitman, B. Wünsch, 2018, European journal of medicinal chemistry.

Synthesis of Aminoethyl‐Substituted Piperidine Derivatives as σ1 Receptor Ligands with Antiproliferative Properties

E. Laurini, D. Marson, S. Pricl, 2022, ChemMedChem.

Design, (Radio)Synthesis, and in Vitro and in Vivo Evaluation of Highly Selective and Potent Matrix Metalloproteinase 12 (MMP-12) Inhibitors as Radiotracers for Positron Emission Tomography.

M. Schäfers, B. Wünsch, S. Hermann, 2018, Journal of medicinal chemistry.

Phenylethylene glycol-derived LpxC inhibitors with diverse Zn2+-binding groups

J. Kirchmair, F. Galla, Ralph Holl, 2019, Tetrahedron.