Takeshi Honda

发表

Potentiation of insulin secretion and improvement of glucose intolerance by combining a novel G protein-coupled receptor 40 agonist DS-1558 with glucagon-like peptide-1 receptor agonists.

S. Kume, Koji Matsumoto, M. Inoue, 2014, European journal of pharmacology.

Synthesis and anti-influenza evaluation of polyvalent sialidase inhibitors bearing 4-guanidino-Neu5Ac2en derivatives.

M. Yamashita, Takeshi Honda, T. Masuda, 2002, Bioorganic & medicinal chemistry letters.

Substituents at the naphthalene C3 position of (-)-Cercosporamide derivatives significantly affect the maximal efficacy as PPARγ partial agonists.

K. Wakabayashi, Shinko Hayashi, J. Ohsumi, 2012, Bioorganic & medicinal chemistry letters.

Novel antibody drug conjugates containing exatecan derivative-based cytotoxic payloads.

Shinji Ashida, K. Morita, Hideki Miyazaki, 2016, Bioorganic & medicinal chemistry letters.

Synthesis of Tetra- and Penta-Substituted Pyrrole Derivatives from Azazirconacyclopentene and Acyl Halide in the Presence of CuCl

M. Mori, Takeshi Honda, F. Dekura, 1997 .

Discovery of DS-1558: A Potent and Orally Bioavailable GPR40 Agonist.

S. Ito, Koji Matsumoto, Masakazu Hirouchi, 2015, ACS medicinal chemistry letters.

Synthesis and anti-influenza evaluation of polyvalent sialidase inhibitors bearing 4-guanidino-Neu5Ac2en derivatives.

M. Yamashita, Takeshi Honda, T. Masuda, 2003, Chemical & pharmaceutical bulletin.

Millimeter- and Submillimeter-Wave Spectra of CuF and AgF in the X1Σ+ Electronic Ground States

Takeshi Honda, T. Okabayashi, M. Tanimoto, 2001 .

Synthesis and in vivo influenza virus-inhibitory effect of ester prodrug of 4-guanidino-7-O-methyl-Neu5Ac2en.

M. Yamashita, Yoshiyuki Kobayashi, S. Kubo, 2009, Bioorganic & medicinal chemistry letters.

AN EFFICIENT SYNTHESIS OF (35,5S)-5-[3,3-DIMETHYL-1-(ο-TOLYL)-6-OXO-2H-PYRIDIN-4-YL]-PIPERIDINE-3-CARBOXAMIDE AS POTENT RENIN INHIBITOR

Y. Mori, Takahiro Nagayama, T. Nishi, 2014 .

Total Synthesis of Bleomycin A2 and Related Agents. 2. Synthesis of (-)-Pyrimidoblamic Acid, epi-(+)-Pyrimidoblamic Acid, (+)-Desacetamidopyrimidoblamic Acid, and (-)-Descarboxamidopyrimidoblamic Acid

D. Boger, Q. Dang, Takeshi Honda, 1994 .

A Stereocontrolled Construction of 2-Deoxy-β-glycosidic Linkages via 1,2-trans-β-Glycosidation of 2-Deoxy-2-[(p-methoxyphenyl)thio] glycopyranosyl N,N,N′,N′-Tetramethylphosphoroamidates

S. Ikegami, S. Hashimoto, Takeshi Honda, 1992 .

SYNTHESIS OF AZAZIRCONACYCLOPROPANES AND AZAZIRCONACYCLOPENTENES FROM ETA 2-IMINOSILAACYL COMPLEXES

M. Mori, Takeshi Honda, Shoichi Satoh, 1995 .

Total Synthesis of Bleomycin A2 and Related Agents. 1. Synthesis and DNA Binding Properties of the Extended C-Terminus: Tripeptide S, Tetrapeptide S, Pentapeptide S, and Related Agents

D. Boger, S. Colletti, Takeshi Honda, 1994 .

Total Synthesis of Bleomycin A2 and Related Agents. Part 2. Synthesis of (‐)‐Pyrimidoblamic Acid (VI), epi‐(+)‐Pyrimidoblamic Acid (VII), (+) ‐Desacetamidopyrimidoblamic Acid (V), and (‐)‐ Descarboxamidopyrimidoblamic Acid (VIII).

D. Boger, Q. Dang, Takeshi Honda, 1994 .

A new and general glycosidation method for podophyllum lignan glycosides

S. Ikegami, S. Hashimoto, Takeshi Honda, 1991 .

A rapid and efficient synthesis of 1,2-trans-β-linked glycosides via benzyl- or benzoyl-protected glycopyranosyl phosphates

S. Ikegami, S. Hashimoto, Takeshi Honda, 1989 .

“Armed-disarmed” glycosidation strategy based on glycosyl donors and acceptors carrying phosphoroamidate as a leaving group: A convergent synthesis of globotriaosylceramide

H. Abe, S. Ikegami, S. Hashimoto, 1997 .

Total Synthesis of (−)-Pyrimidoblamic Acid and Deglycobleomycin A2†

D. Boger, Takeshi Honda, Royce F. Menezes, 1993 .

Oligosaccharide synthesis based on glycosyl donors and acceptors carrying phosphorus-containing leaving groups

S. Ikegami, S. Hashimoto, Takeshi Honda, 1997 .

Total Synthesis of Bleomycin A2 and Related Agents. 4. Synthesis of the Disaccharide Subunit 2-O-(3-O-Carbamoyl-.alpha.-D-mannopyranosyl)-L-gulopyranose and Completion of the Total Synthesis of Bleomycin A2

D. Boger, Takeshi Honda, 1994 .

An efficient construction of 1,2-trans-β-glycosidic linkages capitalizing on glycopyranosyl N,N,N′,N′-tetramethylphosphroamidates as shelf-stable glycosyl donors

S. Ikegami, S. Hashimoto, Takeshi Honda, 1992 .

AN EFFICIENT CONSTRUCTION OF 1, 2-TRANS-β-GLYCOSIDIC LINKAGES VIA BENZYL-PROTECTED GLYCOPYRANOSYL P, P-DIPHENYL-N-(p-TOLUENESULFONYL)-PHOSPHINIMIDATES

S. Ikegami, S. Hashimoto, Takeshi Honda, 1990 .

Oligosaccharide Synthesis Based on Glycosyl Donors and Acceptors Carrying Phosphorus-Containing Leaving Groups.

S. Ikegami, S. Hashimoto, Takeshi Honda, 1997 .

Highly Selective Glycosidation Reactions Capitalizing on Phosphorus-containing Leaving Groups

S. Ikegami, S. Hashimoto, M. Nakajima, 1995 .

A Mild and Rapid 1,2-trans-Glycosidation Method via Benzoyl-protected Glycopyranosyl. P,P-Diphenyl-N-(p-toluenesulfonyl)phosphinimidates

S. Ikegami, S. Hashimoto, Takeshi Honda, 1990 .

Total Synthesis of Bleomycin A2 and Related Agents. Part 4. Synthesis of the Disaccharide Subunit: 2-O-(3-O-Carbamoyl-α-D- mannopyranosyl)-L-gulopyranose and Completion of the Total Synthesis of Bleomycin A2.

D. Boger, Takeshi Honda, 1994 .

An Efficient Construction of 1,2-trans-β-Glycosidic Linkages via Benzyl-Protected Glycopyranosyl P,P-Diphenyl-N-(p-toluenesulfonyl) phosphinimidates.

S. Ikegami, S. Hashimoto, Takeshi Honda, 1991 .

Synthesis and anti-influenza evaluation of orally active bicyclic ether derivatives related to zanamivir.

Takeshi Masuda, Takanori Tomozawa, M. Yamashita, 2003, Bioorganic & medicinal chemistry letters.

Synthesis of 4-guanidino-7-modified-Neu5Ac2en derivatives and their biological activities as influenza sialidase inhibitors

M. Yamashita, S. Shibuya, Yoshiyuki Kobayashi, 2009 .

Synthesis and anti-influenza virus activity of 4-guanidino-7-substituted Neu5Ac2en derivatives.

Yoshiyuki Kobayashi, Takeshi Masuda, M. Yamashita, 2002, Bioorganic & medicinal chemistry letters.

Studies on the synthesis of bleomycin A2 : observations on a diastereoselective imine addition reaction for C2-acetamido side chain introduction

D. Boger, Takeshi Honda, 1993 .

Synthesis of 4‐Guanidino‐7‐modified‐Neu5Ac2en Derivatives and Their Biological Activities as Influenza Sialidase Inhibitors

Takeshi Honda, Masuda Takeshi, 2010 .

Synthesis and anti-influenza virus activity of 7-O-alkylated derivatives related to zanamivir.

Satoru Kaneko, Takeshi Masuda, M. Yamashita, 2002, Bioorganic & medicinal chemistry letters.

Discovery of 3-aryl-3-ethoxypropanoic acids as orally active GPR40 agonists.

Koji Matsumoto, N. Watanabe, M. Inoue, 2014, Bioorganic & medicinal chemistry letters.

Novel Cyclization Reaction by Tandem Michael Addition -Dieckmann Condensation Using Stannyl Anion Generated from Bu3SnSiMe3 and F−

M. Mori, Takeshi Honda, 1994 .

Synthesis and Antiinfluenza Virus Activity of 7-O-Alkylated Derivatives Related to Zanamivir.

M. Yamashita, Takeshi Honda, T. Masuda, 2002 .

Synthesis and biological evaluation of novel (-)-Cercosporamide derivatives as potent selective PPARγ modulators.

K. Wakabayashi, Shinko Hayashi, J. Ohsumi, 2012, European journal of medicinal chemistry.

Monoclonal Antibodies as Tailor-Made Hosts for Porphyrins

A. Harada, T. Miwatani, M. Kamachi, 1990 .

Synthesis and Antiinfluenza Evaluation of Orally Active Bicyclic Ether Derivatives Related to Zanamivir.

M. Yamashita, S. Shibuya, T. Tomozawa, 2003 .

Generation of efficient mutants of endoglycosidase from Streptococcus pyogenes and their application in a novel one-pot transglycosylation reaction for antibody modification

Y. Sekiguchi, Takeshi Honda, Kensuke Nakamura, 2018, PloS one.

Pharmacokinetic and Pharmacodynamic Profiles of Glyco-Modified Atrial Natriuretic Peptide Derivatives Synthesized Using Chemo-enzymatic Synthesis Approaches.

Ryuki Miyauchi, Y. Sekiguchi, Y. Mori, 2018, Bioconjugate chemistry.

Optimization of 3-aryl-3-ethoxypropanoic acids and discovery of the potent GPR40 agonist DS-1558.

Koji Matsumoto, Masakazu Hirouchi, N. Watanabe, 2015, Bioorganic & medicinal chemistry.

Total Synthesis of Bleomycin A2 and Related Agents. 3. Synthesis and Comparative Evaluation of Deglycobleomycin A2,Epideglycobleomycin A2, Deglycobleomycin A1, and Desacetamido-, Descarboxamido-, Desmethyl-, and Desimidazolyldeglycobleomycin A2

D. Boger, S. Colletti, Takeshi Honda, 1994 .