R. D. de Zeeuw

发表

A single-column procedure on Bond Elut Certify for systematic toxicological analysis of drugs in plasma and urine.

X. H. Chen, J. Wijsbeek, J. Franke, 1992, Journal of forensic sciences.

Transdermal drug delivery: efficacy and potential applications of the penetration enhancer Azone.

J. Wiechers, R. D. de Zeeuw, 1990, Drug design and delivery.

Identification of cannabivarins in hashish by a new method of combined gas chromatography-mass-spectrometry.

T. Vree, J. V. van Rossum, C. V. van Ginneken, 1971, Clinica chimica acta; international journal of clinical chemistry.

Rapid extraction of clenbuterol from human and calf urine using empore C8 extraction disks.

J. Franke, R. D. de Zeeuw, A. Koole, 1999, Journal of analytical toxicology.

A rapid gas chromatographic method for the fingerprinting of illicit cocaine samples.

R. D. de Zeeuw, J. G. Ensing, C. Racamy, 1992, Journal of forensic sciences.

Substance identification: the weak link in analytical toxicology.

R. D. de Zeeuw, R. A. de Zeeuw, 2004, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

The prevalence of CYP2D6 and CYP2C19 genotypes in a population of healthy Dutch volunteers

R. A. Zeeuw, J. Jonkman, J. Jonkman, 2001, European Journal of Clinical Pharmacology.

Ion suppression in the determination of clenbuterol in urine by solid-phase extraction atmospheric pressure chemical ionisation ion-trap mass spectrometry.

H. Niederländer, G. D. de Jong, M. V. van Hout, 2003, Rapid communications in mass spectrometry : RCM.

Non-equilibrium solid-phase microextraction coupled directly to ion-trap mass spectrometry for rapid analysis of biological samples.

H. Niederländer, G. D. de Jong, M. V. van Hout, 2002, The Analyst.

Impact of structural differences on the in vitro glucuronidation kinetics of potentially dopaminergic hydroxy-2-aminotetralins and naphthoxazines using rat and human liver microsomes.

R. A. Zeeuw, B. Drenth, P. J. Swart, 1991, Pharmacology & toxicology.

Reversed-phase liquid chromatographic method with amperometric detection for the determination of the dopamine agonist 2-(N-propyl-N-2-thienylethylamino)-5-hydroxytetralin (N-0437) in human plasma and urine.

B. Drenth, P. J. Swart, R. D. de Zeeuw, 1990, Journal of chromatography.

An optimized methodology for combined phenotyping and genotyping on CYP2D6 and CYP2C19

J. Jonkman, B. Oosterhuis, R. D. de Zeeuw, 2001, European Journal of Clinical Pharmacology.

CYP2D6 and CYP2C19 activity in a large population of Dutch healthy volunteers: indications for oral contraceptive-related gender differences

R. A. Zeeuw, B. Wilffert, J. Wieling, 1999, European Journal of Clinical Pharmacology.

Spherical molecularly imprinted polymer particles: A promising tool for molecular recognition in capillary electrokinetic separations

D. Sherrington, T. de Boer, K. Ensing, 2002, Electrophoresis.

Kinetics of carbamazepine and carbamazepine‐epoxide, determined by use of plasma and saliva

T. Oei, R. D. de Zeeuw, E. van der Kleijn, 1978, Clinical pharmacology and therapeutics.

On-line coupling of solid-phase extraction with mass spectrometry for the analysis of biological samples. III. Determination of prednisolone in serum.

H. Niederländer, A. Bruins, G. D. de Jong, 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Muscarinic M2 receptors in bovine tracheal smooth muscle: discrepancies between binding and function.

R. A. Zeeuw, J. Zaagsma, R. V. van Amsterdam, 1988, European journal of pharmacology.

Isolation of acidic, neutral, and basic drugs from whole blood using a single mixed-mode solid-phase extraction column.

X. H. Chen, J. Wijsbeek, J. Franke, 1992, Journal of analytical toxicology.

The metabolic fate of the dopamine agonist 2-(N-propyl-N-2-thienylethylamino)-5-hydroxytetralin in rats after intravenous and oral administration. I. Disposition and metabolic profiling.

T. K. Gerding, B. Drenth, A. Horn, 1990, Xenobiotica; the fate of foreign compounds in biological systems.

Comparative study of the bronchodilating effects of (-)- and (+)-oxyphenonium bromide.

D. Postma, G. Koëter, R. D. de Zeeuw, 1988, British journal of clinical pharmacology.

Pharmacokinetics of sustained release theophylline in low and high multidose regimens.

J. Jonkman, G. Koëter, R. D. de Zeeuw, 1981, British journal of clinical pharmacology.

Rapid micromethod for the analysis of mitotane and its metabolite in plasma by gas chromatography with electron-capture detection.

R. D. de Zeeuw, R. Benecke, B. Vetter, 1987, Journal of chromatography.

Methodological aspects of quantitative receptor assays.

K. Ensing, R. D. de Zeeuw, J. S̆misterová, 1994, Journal of pharmaceutical and biomedical analysis.

Percutaneous Absorption and Elimination of the Penetration Enhancer Azone in Humans

J. Wiechers, J. Jonkman, B. Drenth, 1987, Pharmaceutical Research.

Identification with liquid chromatography-ionspray mass spectrometry of the metabolites of the enantiomers N-methyl dextrorphan and N-methyl levorphanol after rat liver perfusion.

B. Drenth, K. Ensing, D. Meijer, 1993, Biological mass spectrometry.

Vapor-programmed preparative thin-layer chromatography, a technique with improved resolving power.

J. Wijsbeek, R. D. de Zeeuw, 1970, Analytical chemistry.

The metabolic fate of the dopamine agonist 2-(N-propyl-N-2-thienylethylamino)-5-hydroxytetralin in rats after intravenous and oral administration. II. Isolation and identification of metabolites.

T. K. Gerding, B. Drenth, A. Horn, 1990, Xenobiotica; the fate of foreign compounds in biological systems.

Selectivity in capillary electrokinetic separations

T. de Boer, K. Ensing, G. D. de Jong, 1999, Electrophoresis.

Recent innovations in the use of charged cyclodextrins in capillary electrophoresis for chiral separations in pharmaceutical analysis

T. de Boer, K. Ensing, G. D. de Jong, 2000, Electrophoresis.

Determination of enantiomeric purity of the new D-2 dopamine agonist 2-(N-propyl-N-2-thienylethylamino)-5-hydroxytetralin (N-0437) by reversed-phase high-performance liquid chromatography after pre-column derivatization with D(+)-glucuronic acid.

T. K. Gerding, B. Drenth, A. Horn, 1989, Journal of chromatography.

Feasibility of the direct coupling of solid-phase extraction-pipette tips with a programmed-temperature vaporiser for gas chromatographic analysis of drugs in plasma.

G. D. de Jong, J. Franke, M. V. van Hout, 2002, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

An enzymic digestion and solid-phase extraction procedure for the screening for acidic, neutral, and basic drugs in liver using gas chromatography for analysis.

X. H. Chen, J. Wijsbeek, J. Franke, 1996, Journal of analytical toxicology.

Separation and identification of thiobarbiturates by means of thin-layer chromatography.

J. Wijsbeek, R. D. de Zeeuw, 1969, Pharmaceutisch weekblad.

The determination of the acid dissociation constants of barbiturates by an accurate method of pH measurement.

R. D. de Zeeuw, D. Doornbos, 1969, Pharmaceutisch weekblad.

Intra- and inter-species comparisons of biliary metabolic profiles of butoprozine by high performance liquid chromatography.

R. D. de Zeeuw, F. Overzet, 1985, Xenobiotica; the fate of foreign compounds in biological systems.

High-performance liquid chromatographic determination of reproterol in plasma using on-line trace enrichment and amperometric detection with a rotating working electrode.

R. Hageman, J. Jonkman, R. D. de Zeeuw, 1983, Journal of chromatography.

Dynamically coated capillaries improve the identification power of capillary zone electrophoresis for basic drugs in toxicological analysis.

K. Ensing, J. Franke, R. D. de Zeeuw, 2001, Journal of chromatography. A.

Evaluation of capillary electrophoretic techniques towards systematic toxicological analysis.

K. Ensing, J. Franke, R. D. de Zeeuw, 1999, Journal of chromatography. A.

Solid phase extraction of morphine from whole blood by means of Bond Elut Certify columns.

K. Ensing, P. Zweipfenning, X. H. Chen, 1993, Journal of forensic sciences.

Mephenytoin as a probe for CYP2C19 phenotyping:effect of sample storage, intra-individual reproducibility and occurrence of adverse events.

D. Touw, J. Wieling, J. Jonkman, 2001, British journal of clinical pharmacology.

Discrepancies in the specific activity of 3H-N-methylscopolamine as determined by mass spectrometry and radioreceptor assay due to racemisation.

K. Ensing, R. D. de Zeeuw, D. Bloemhof, 1988, Journal of receptor research.

Determination of clomipramine and desmethylclomipramine in plasma by means of liquid chromatography.

B. Drenth, J. Korf, H. V. van Praag, 1977, Journal of chromatography.

Cannabinoids with a Propyl Side Chain in Cannabis: Occurrence and Chromatographic Behavior

T. Vree, J. V. van Rossum, D. Breimer, 1972, Science.

Determination of the dopamine D2 agonist N-0923 and its major metabolites in perfused rat livers by HPLC-UV-atmospheric pressure ionization mass spectrometry.

A. Bruins, P. Tepper, R. D. de Zeeuw, 1994, Journal of analytical toxicology.

Solid-phase extraction for the screening of acidic, neutral and basic drugs in plasma using a single-column procedure on Bond Elut Certify.

X. H. Chen, J. Wijsbeek, J. Franke, 1990, Journal of chromatography.

Impact of biological matrix, drug concentration, and method of isolation on detectability and variability of retention index values in gas chromatography.

M. Bogusz, J. Franke, J. Wijsbeek, 1985, Journal of analytical toxicology.

Development of a Radioreceptor Assay for the D2-Selective Dopamine Agonist N-0437

K. Ensing, R. D. de Zeeuw, W. G. in't Hout, 1988, Pharmaceutical Research.

Application of radioreceptor assays for systematic toxicological analysis--2. Theoretical considerations and evaluation.

K. Ensing, A. Egberts, I. Bosman, 1994, Journal of pharmaceutical and biomedical analysis.

Application of radioreceptor assays for systematic toxicological analysis--1. Procedures for radioreceptor assays for antihistaminics, anticholinergics and benzodiazepines.

K. Ensing, A. Egberts, I. Bosman, 1994, Journal of pharmaceutical and biomedical analysis.

Centrifugation or filtration in quantitative radioreceptor assays.

K. Ensing, K. G. Feitsma, R. D. de Zeeuw, 1986, Journal of biochemical and biophysical methods.

Evaluation of a purification procedure for the muscarinic receptor for the purpose of quantitative receptor assays of anticholinergics. Part B: The solubilized receptor.

K. Ensing, R. D. de Zeeuw, J. de Boer, 1995, Preparative biochemistry.

SPEC disc solid-phase extraction for rapid broad-spectrum drug screening in urine.

J. Wijsbeek, J. Franke, R. D. de Zeeuw, 2000, Journal of analytical toxicology.

Comparison of intravenous and endobronchial atropine: a pharmacokinetic and -dynamic study in pigs.

K. Ensing, H. Stoeckel, J. Schüttler, 1989, European journal of anaesthesiology.

Determination of oxyphenonium bromide in plasma and urine by means of ion-pair extraction, derivatization and gas chromatography-electron-capture detection.

J. Jonkman, R. D. de Zeeuw, N. Orie, 1977, Journal of chromatography.

Evaluation of the programmed temperature vaporiser for large-volume injection of biological samples in gas chromatography.

G. D. de Jong, M. V. van Hout, J. Franke, 1999, Journal of chromatography. B, Biomedical sciences and applications.

Comparison of some matrix modifiers for the determination of cadmium in urine by atomic-absorption spectrometry with electrothermal atomisation.

K. G. Feitsma, J. Franke, R. D. de Zeeuw, 1984, The Analyst.

Hemoperfusion-hemodialysis ineffective for paraquat removal in life-threatening poisoning?

L. V. Van Gaal, M. D. de Broe, G. Verpooten, 1985, Journal of toxicology. Clinical toxicology.

An unusual case of carbamazepine poisoning with a near-fatal relapse after two days.

J. Gimbrère, R. D. de Zeeuw, E. van der Kleijn, 1979, Clinical toxicology.

Rapid and sensitive liquid chromatographic determination of carbamazepine suitable for use in monitoring multiple-drug anticonvulsant therapy.

R. D. de Zeeuw, H. G. Westenberg, 1976, Journal of chromatography.

An unusual case of carbamazepine poisoning with a near-fatal relapse after two days.

J. Gimbrère, R. D. de Zeeuw, H. G. Westenberg, 1979, Veterinary and human toxicology.

Glucuronidation of labetalol at the two hydroxy positions by bovine liver microsomes. Isolation, purification, and structure elucidation of the glucuronides of labetalol.

T. K. Gerding, R. D. de Zeeuw, N. Niemeijer, 1991, Drug metabolism and disposition: the biological fate of chemicals.

A rapid thin layer chromatographic procedure to identify poor and extensive oxidative drug metabolizers in man using dextromethorphan.

J. Jonkman, J. Franke, R. D. de Zeeuw, 1992, Die Pharmazie.

Multicenter evaluation of ultrafiltration, dialysis, and thermal coagulation as sample pretreatment methods for the colorimetric determination of paraquat in blood and tissues.

M. Bogusz, J. Wijsbeek, J. Franke, 1986, Journal of forensic sciences.

Solid-phase extraction procedures in systematic toxicological analysis.

J. Franke, R. D. de Zeeuw, 1998, Journal of chromatography. B, Biomedical sciences and applications.

Application of Empore C-8 extraction disks for screening urine in systematic toxicological analysis.

K. Ensing, X. H. Chen, J. Franke, 1992, Journal of forensic sciences.

Disposition and Metabolic Profiling of the Penetration Enhancer Azone. I. In Vivo Studies: Urinary Profiles of Hamster, Rat, Monkey, and Man

J. Wiechers, B. Drenth, R. D. de Zeeuw, 1990, Pharmaceutical Research.

Percutaneous absorption, metabolic profiling, and excretion of the penetration enhancer azone after multiple dosing of an azone-containing triamcinolone acetonide cream in humans.

B. Drenth, J. Wiechers, J. Jonkman, 1990, Journal of pharmaceutical sciences.

Pitfalls and solutions in the development of a fully automated solid-phase extraction method for drug screening purposes in plasma and whole blood.

J P Franke, R A de Zeeuw, K. Ensing, 1993, Journal of analytical toxicology.

Study of lot-to-lot reproducibilities of Bond Elut Certify and Clean Screen DAU mixed-mode solid-phase extraction columns in the extraction of drugs from whole blood.

X. H. Chen, J. Wijsbeek, J. Franke, 1993, Journal of chromatography.

Determination of carbisocaine, heptacaine and pentacaine in plasma by capillary gas chromatography with nitrogen-selective detection.

J. Wijsbeek, R. D. de Zeeuw, V. Marko, 1986, Journal of pharmaceutical and biomedical analysis.

Applicability of capillary gas chromatography to systematic toxicological analysis: occurrence of concentration-dependent retention behavior.

M. Bogusz, J. Wijsbeek, J. Franke, 1983, Journal of analytical toxicology.

How to approach substance identification in qualitative bioanalysis.

J. Franke, R. D. de Zeeuw, J. Hartstra, 2000, Journal of chromatography. B, Biomedical sciences and applications.

Multi-residue analysis of anabolics in calf urine using high-performance liquid chromatography with diode-array detection.

J. Franke, R. D. de Zeeuw, A. Koole, 1999, Journal of Chromatography B: Biomedical Sciences and Applications.

Impact of hot and humid tropical conditions on Toxi-Lab thin-layer chromatographic systems for the screening of basic and neutral drugs.

J. Franke, R. D. de Zeeuw, M. van Halem, 1994, Journal of Analytical Toxicology.

Isotopic separations of the drug N-0437 and its diastereoisomeric glucuronides by high-performance liquid chromatography.

T. K. Gerding, B. Drenth, R. D. de Zeeuw, 1988, Analytical biochemistry.

Potentials of wide-bore fused silica capillary columns for substance identification by means of retention indices.

J. Wijsbeek, J. Franke, R. D. de Zeeuw, 1986, Journal of analytical toxicology.

Systematic analysis of solvents and other volatile substances by gas chromatography.

J. Franke, J. Wijsbeek, R. D. de Zeeuw, 1988, Journal of analytical toxicology.

Toxicological analysis of whole blood samples by means of Bond-Elut Certify columns and gas chromatography with nitrogen-phosphorus detection.

P. Zweipfenning, J. Franke, R. D. de Zeeuw, 1994, Journal of chromatography. A.

System evaluation and substance identification in systematic toxicological analysis by the mean list length approach.

J. Franke, R. D. de Zeeuw, P. Schepers, 1983, Journal of analytical toxicology.

Impact of tropical conditions on thin layer chromatography in analytical toxicology: high temperatures and moderate humidities.

J. Franke, R. D. de Zeeuw, B. Kam, 1992, Journal of forensic sciences.

Pharmacokinetics of the dopamine D2 agonist S(-)-2-(N-propyl-N-2-thienylethylamino)-5-hydroxytetralin in freely moving rats.

R. D. de Zeeuw, P. Swart, R. A. de Zeeuw, 1993, Journal of pharmaceutical sciences.

First-pass effect after rectal administration of thiazinamium methylsulfate.

J. Jonkman, J. Wijsbeek, R. D. de Zeeuw, 1979, Journal of pharmaceutical sciences.

Determination of thiazinamium sulphoxide in urine by means of amberlite XAD-2 column chromatography and thin-layer densitometry.

J. Jonkman, J. Wijsbeek, R. D. de Zeeuw, 1976, Journal of chromatography.

Stability of theophylline in serum, plasma, and saliva stored at different temperatures.

J. Jonkman, J. Franke, R. D. de Zeeuw, 1981, Clinical chemistry.

Unusual plasma level oscillations of clomipramine in man: a pharmacokinetic and pharmacodynamic dilemma.

H. V. van Praag, H. D. De Cuyper, R. D. de Zeeuw, 1980, Postgraduate medical journal.

Bioanalysis and pharmacokinetics of clomipramine and desmethylclomipramine in man by means of liquid chromatography.

J. Korf, H. V. van Praag, H. D. De Cuyper, 1977, Postgraduate medical journal.

Direct enantiomeric separation of mianserin and 6-azamianserin derivatives using chiral stationary phases.

H. Wikström, U. Selditz, Y. Liao, 1998, Journal of chromatography. A.

Solubilized benzodiazepine receptors for use in receptor assays.

K. Ensing, M. Janssen, M. Stegeman, 1996, Journal of pharmaceutical and biomedical analysis.

Impact of biological matrix and isolation methods on detectability and interlaboratory variations of TLC Rf-values in systematic toxicological analysis.

M. Bogusz, J. Franke, J. Wijsbeek, 1984, Journal of Analytical Toxicology.

Influence of the biological matrix on retention behaviour in thin-layer chromatography: evidence of systematic differences between pure and extracted drugs.

M. Bogusz, J. Franke, R. D. de Zeeuw, 1985, Journal of chromatography.

Influence of biological matrix on retention behaviour and identification possibilities of selected neutral and acidic drugs in thin layer chromatography. An interlaboratory investigation.

M. Bogusz, J. Wijsbeek, J. Franke, 1986, Journal of analytical toxicology.

Erratic data in thin layer chromatography due to anomalous behavior of correction standards.

M. Bogusz, J. Franke, R. D. de Zeeuw, 1985, Journal of analytical toxicology.

Impact of urine matrix and isolation procedure on retention behaviour of basic drugs in thin-layer chromatography.

J. Franke, J. Wijsbeek, R. D. de Zeeuw, 1988, Journal of pharmaceutical and biomedical analysis.

Optimization of thin layer chromatography for toxicological screening: applicability of shorter development distances.

J. Franke, R. D. de Zeeuw, J. Bosman, 1982, Journal of analytical toxicology.

Screening for the presence of drugs in serum and urine using different separation modes of capillary electrophoresis.

K. Ensing, J. Franke, R. D. de Zeeuw, 2001, Forensic science international.

Determination of basic drugs extracted from biological matrices by means of solid-phase extraction and wide-bore capillary gas chromatography with nitrogen-phosphorus detection.

X. H. Chen, J. Wijsbeek, J. Franke, 1994, Journal of analytical toxicology.

Semi-automated solid-phase extraction procedure for drug screening in biological fluids using the ASPEC system in combination with Clean Screen DAU columns.

K. Ensing, X. H. Chen, J. Wijsbeek, 1993, Journal of chromatography.

Novel diffusion cell for in vitro transdermal permeation, compatible with automated dynamic sampling.

K. Ensing, I. Bosman, R. D. de Zeeuw, 1996, Journal of Pharmaceutical and Biomedical Analysis.

Evaluation of a novel diffusion cell for in vitro transdermal permeation: effects of injection height, volume and temperature.

K. Ensing, I. Bosman, R. D. de Zeeuw, 1998, Journal of pharmaceutical and biomedical analysis.

Development and application of a radioreceptor assay for scopolamine.

K. Ensing, R. D. de Zeeuw, G. Ensing, 1988, Arzneimittel-Forschung.

Effect of purification followed by solubilization of receptor material on quantitative receptor assays for anticholinergic drugs.

K. Ensing, R. D. de Zeeuw, J. S̆misterová, 1996, Journal of Pharmaceutical and Biomedical Analysis.

Variations in the bioavailability of thiazinamium methylsulfate

J. Jonkman, J. Wijsbeek, R. D. de Zeeuw, 1977, Clinical pharmacology and therapeutics.

Separation and identification of neuropeptide Y, two of its fragments and their degradation products using capillary electrophoresis-mass spectrometry.

T. de Boer, K. Ensing, N. Schreuder, 1999, Journal of chromatography. B, Biomedical sciences and applications.

No Effect of Influenza Vaccination on Theophylline Pharmacokinetics as Studied by Ultraviolet Spectrophotometry, HPLC, and EMIT Assay Methods

J. Jonkman, B. Oosterhuis, R. D. de Zeeuw, 1988, Therapeutic drug monitoring.