E. Puccetti

发表

Upon Drug-Induced Apoptosis Expression of Prostate-apoptosis-response-gene-4 Promotes Cleavage of Caspase-8, Bid and Mitochondrial Release of Cytochrome c

D. Nowak, S. Boehrer, M. Bergmann, 2004, Hematology.

PIC-1/SUMO-1-Modified PML-Retinoic Acid Receptor α Mediates Arsenic Trioxide-Induced Apoptosis in Acute Promyelocytic Leukemia

T. Sternsdorf, K. Jensen, H. Will, 1999, Molecular and Cellular Biology.

Opposite Effects of the Acute Promyelocytic Leukemia PML-Retinoic Acid Receptor a (RAR a ) and PLZF-RAR a Fusion Proteins on Retinoic Acid Signalling

C. Peschle, P. Pelicci, U. Testa, 1996 .

Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling

C. Peschle, P. Pelicci, U. Testa, 1997, Molecular and cellular biology.

sensitivity to STI571 interferes with the transformation potential of BCR/ABL and increases Targeting of the N-terminal coiled coil oligomerization interface of BCR

S. Boehrer, A. Bianchini, C. Nervi, 2013 .

Targeting of the N-terminal coiled coil oligomerization interface of BCR interferes with the transformation potential of BCR-ABL and increases sensitivity to STI571.

S. Boehrer, A. Bianchini, C. Nervi, 2003, Blood.

progenitor cells translocation products by increasing the self-renewal of very primitive -Catenin contributes to leukemogenesis induced by AML-associated γ

R. Henschler, S. Boehrer, O. Ottmann, 2013 .

Acute promyelocytic leukemia: PML/RARα and the leukemic stem cell

M. Ruthardt, E. Puccetti, 2004, Leukemia.

Gamma-catenin contributes to leukemogenesis induced by AML-associated translocation products by increasing the self-renewal of very primitive progenitor cells.

R. Henschler, S. Boehrer, O. Ottmann, 2004, Blood.

Leukemia-associated translocation products able to activate RAS modify PML and render cells sensitive to arsenic-induced apoptosis

O. Ottmann, D. Hoelzer, S. Güller, 2003, Oncogene.

The t(6;9) associated DEK/CAN fusion protein targets a population of long-term repopulating hematopoietic stem cells for leukemogenic transformation

R. Henschler, M. Ruthardt, B. Rüster, 2010, Leukemia.

Prostate apoptosis response gene-4 (par-4) abrogates the survival function of p185(BCR-ABL) in hematopoietic cells.

S. Boehrer, M. Bergmann, D. Hoelzer, 2004, Experimental hematology.

Folinic acid antagonizes methotrexate-induced differentiation of monocyte progenitors

O. Ottmann, D. Hoelzer, M. Ruthardt, 2002, Rheumatology International.

5-Lipoxygenase is a candidate target for therapeutic management of stem cell-like cells in acute myeloid leukemia.

D. Steinhilber, E. Proschak, I. Fleming, 2014, Cancer research.

Direct interaction of PU.1 with oncogenic transcription factors reduces its serine phosphorylation and promoter binding

M. Frech, E. Puccetti, S. Beez, 2012, Leukemia.

BCR-ABL mediates arsenic trioxide-induced apoptosis independently of its aberrant kinase activity.

O. Ottmann, D. Hoelzer, S. Güller, 2000, Cancer research.

Prostate-apoptosis-response-gene-4 increases sensitivity to TRAIL-induced apoptosis.

D. Nowak, S. Boehrer, D. Hoelzer, 2005, Leukemia research.

The integrity of the charged pocket in the BTB/POZ domain is essential for the phenotype induced by the leukemia-associated t(11;17) fusion protein PLZF/RARalpha.

S. Boehrer, C. Nervi, O. Ottmann, 2005, Cancer research.

In lymphatic cells par-4 sensitizes to apoptosis by down-regulating bcl-2 and promoting disruption of mitochondrial membrane potential and caspase activation.

V. Rangnekar, S. Boehrer, D. Hoelzer, 2002, Cancer research.

Mitochondrial Membrane Potential and Caspase Activation Down-Regulating Bcl-2 and Promoting Disruption of In Lymphatic Cells Par-4 Sensitizes to Apoptosis by Updated

V. Rangnekar, D. Hoelzer, K. Chow, 2002 .

Arsenic but not all-trans retinoic acid overcomes the aberrant stem cell capacity of PML/RARalpha-positive leukemic stem cells.

R. Henschler, D. Hoelzer, M. Ruthardt, 2007, Haematologica.

Targeting the Acute Promyelocytic Leukemia-Associated Fusion Proteins PML/RARα and PLZF/RARα with Interfering Peptides

E. Puccetti, P. Demmer, S. Beez, 2012, PloS one.

Deregulated expression of prostate apoptosis response gene-4 in less differentiated lymphocytes and inverse expressional patterns of par-4 and bcl-2 in acute lymphocytic leukemia.

V. Rangnekar, S. Boehrer, D. Hoelzer, 2001, The hematology journal : the official journal of the European Haematology Association.

Advances in Brief BCR-ABL Mediates Arsenic Trioxide-induced Apoptosis Independently of Its Aberrant Kinase Activity 1

O. Ottmann, D. Hoelzer, S. Güller, 2000 .

AML-associated translocation products block vitamin D(3)-induced differentiation by sequestering the vitamin D(3) receptor.

P. Pelicci, F. Chiaradonna, S. Boehrer, 2002, Cancer research.

management of stem cell-like cells in acute myeloid leukemia 5-lipoxygenase is a candidate target for therapeutic

D. Steinhilber, E. Proschak, I. Fleming, 2014 .

Tumor and Stem Cell Biology 5-Lipoxygenase Is a Candidate Target for Therapeutic Management of Stem Cell–like Cells in Acute Myeloid Leukemia

D. Steinhilber, E. Proschak, I. Fleming, 2014 .

Direct interaction of PU.1 with oncogenic transcription factors reduces its serine phosphorylation and promoter binding

M. Frech, E. Puccetti, S. Beez, 2012, Leukemia.

Translocation Products in Acute Myeloid Leukemia Activate the Wnt Signaling Pathway in Hematopoietic Cells

Ping Ji, Hubert Serve, Sven Diederichs, 2004, Molecular and Cellular Biology.

BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility

S. Güller, M. Ruthardt, T. Beissert, 2006, BMC Cancer.

Sulindac Sulfide Reverses Aberrant Self-Renewal of Progenitor Cells Induced by the AML-Associated Fusion Proteins PML/RARα and PLZF/RARα

T. Maier, M. Ruthardt, E. Puccetti, 2011, PloS one.

Acute promyelocytic leukemia: PML/RARalpha and the leukemic stem cell.

M. Ruthardt, E. Puccetti, 2004, Leukemia.

The deacetylase inhibitor LAQ824 induces notch signalling in haematopoietic progenitor cells.

H. Serve, G. Bug, A. Romanski, 2011, Leukemia research.

Down-stream regions of the POZ-domain influence the interaction of the t(11;17)-associated PLZF/RARalpha fusion protein with the histone-deacetylase recruiting co-repressor complex.

S. Boehrer, A. Bianchini, C. Nervi, 2001, The hematology journal : the official journal of the European Haematology Association.

The acute promyelocytic leukaemia specific PML and PLZF proteins localize to adjacent and functionally distinct nuclear bodies

P. Pelicci, M. Fagioli, R. Mannucci, 1998, Oncogene.

Opposite Effects of the Acute Promyelocytic Leukemia PML-Retinoic Acid Receptor a (RAR a ) and PLZF-RAR a Fusion Proteins on Retinoic Acid Signalling

C. Peschle, P. Pelicci, U. Testa, 1997 .

The deacetylase inhibitor LAQ824 induces notch signalling in haematopoietic progenitor cells.

H. Serve, G. Bug, A. Romanski, 2011, Leukemia research.

Targeting of the N-terminal coiled coil oligomerization interface of BCR interferes with the transformation potential of BCR-ABL and increases sensitivity to STI571.

S. Boehrer, A. Bianchini, C. Nervi, 2003, Blood.