E. Deas

发表

Targeting mitochondrial dysfunction in neurodegenerative disease: Part I

N. Wood, S. Gandhi, A. Abramov, 2010, Expert opinion on therapeutic targets.

Targeting mitochondrial dysfunction in neurodegenerative disease: Part II

N. Wood, S. Gandhi, A. Abramov, 2010, Expert opinion on therapeutic targets.

muscleed glucose transport in rat skeletal concentration, glycogen synthase activity, and Levodopa with carbidopa diminishes glycogen

N. Wood, B. Racette, S. Minteer, 2015 .

PINK1 deficiency in β-cells increases basal insulin secretion and improves glucose tolerance in mice

N. Wood, D. Withers, A. Abramov, 2014, Open Biology.

Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress

A. Lees, T. Révész, N. Wood, 2006, Journal of neurochemistry.

PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons

S. Tabrizi, E. Miljan, J. Downward, 2008, PloS one.

HtrA2 deficiency causes mitochondrial uncoupling through the F1F0-ATP synthase and consequent ATP depletion

N. Wood, V. Fedele, K. Cain, 2012, Cell Death and Disease.

What Have PINK1 and HtrA2 Genes Told Us about the Role of Mitochondria in Parkinson's Disease?

N. Wood, S. Gandhi, H. Plun-Favreau, 2008, Annals of the New York Academy of Sciences.

The role of the mitochondrial NCX in the mechanism of neurodegeneration in Parkinson's disease.

N. Wood, A. Abramov, E. Deas, 2013, Advances in experimental medicine and biology.

Loss of PINK1 Increases the Heart's Vulnerability to Ischemia-Reperfusion Injury

M. Mocanu, D. Yellon, S. Davidson, 2013, PloS one.

Loss of PINK 1 Increases the Heart ’ s Vulnerability to Ischemia-Reperfusion Injury

M. Mocanu, D. Yellon, S. Davidson, 2013 .

Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson’s disease

Sonia Gandhi, Emma Deas, Pierluigi Nicotera, 2014, Nature Cell Biology.

Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease.

A. Singleton, J. Hardy, R. Guerreiro, 2009, Brain : a journal of neurology.

PINK1-Associated Parkinson's Disease Is Caused by Neuronal Vulnerability to Calcium-Induced Cell Death

Michael R. Duchen, Nicholas W. Wood, David S. Latchman, 2009, Molecular cell.

A heterozygous effect for PINK1 mutations in Parkinson's disease?

N. Quinn, K. Bhatia, A. Lees, 2006, Annals of neurology.

Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease

Michael J. Devine, C. Dobson, D. Klenerman, 2016, Antioxidants & redox signaling.

PINK1 cleavage at position A103 by the mitochondrial protease PARL

A. Whitworth, N. Wood, A. Renton, 2010, Human molecular genetics.

PINK1 function in health and disease

N. Wood, H. Plun-Favreau, E. Deas, 2009, EMBO molecular medicine.

The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1

J. Downward, N. Wood, L. Martins, 2007, Nature Cell Biology.

Mitophagy and Parkinson's disease: The PINK1–parkin link

N. Wood, H. Plun-Favreau, E. Deas, 2011, Biochimica et biophysica acta.

Degradation of DIAP1 by the N-end rule pathway is essential for regulating apoptosis

A. Paul, T. Tenev, P. Meier, 2003, Nature Cell Biology.

A balanced chromosomal translocation disrupting ARHGEF9 is associated with epilepsy, anxiety, aggression, and mental retardation

Reinhard Ullmann, Cheng Fang, Kirsten Harvey, 2009, Human mutation.

Genetic analysis of mitochondrial protein misfolding in Drosophila melanogaster

D. Dinsdale, L. Martins, V. Fedele, 2012, Cell Death and Differentiation.

Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein

Christopher M. Dobson, Nicholas W. Wood, Carlos W. Bertoncini, 2012, Cell.

Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation

C. Dobson, D. Klenerman, C. Roodveldt, 2015, Proceedings of the National Academy of Sciences.

The glucocerobrosidase E326K variant predisposes to Parkinson's disease, but does not cause Gaucher's disease

J. Hardy, T. Foltynie, P. Jarman, 2013, Movement disorders : official journal of the Movement Disorder Society.

Correction: PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons

S. Tabrizi, E. Miljan, J. Downward, 2008, PLoS ONE.

PINK1 deficiency in b-cells increases basal insulin secretion and improves glucose tolerance in mice.

N. Wood, D. Withers, A. Abramov, 2014, Open biology.

Unraveling LRRK2 Pathogenesis: Common Pathways for Complex Genes?

E. Deas, L. Dunn, 2010, The Journal of Neuroscience.

The mitochondrial protease HtrA 2 is regulated by Parkinson ’ s disease associated kinase PINK 1

J. Downward, N. Wood, L. Martins, 2007 .

Correction: Loss of PINK1 Increases the Heart's Vulnerability to Ischemia-Reperfusion Injury

M. Mocanu, D. Yellon, S. Davidson, 2013, PLoS ONE.

Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson’s disease

D. Dinsdale, S. Gandhi, S. Lehmann, 2014, Nature Cell Biology.

The role of the mitochondrial NCX in the mechanism of neurodegeneration in Parkinson's disease.

N. Wood, A. Abramov, E. Deas, 2013, Advances in experimental medicine and biology.

Geneticanalysisof mitochondrial proteinmisfolding in Drosophila melanogaster

D. Dinsdale, L. Martins, V. Fedele, 2012 .