A. Nakamura

发表

Studies on the mechanisms of tumorigenesis induced by polyetherurethane in rats: production of superoxide, tumor necrosis factor, and interleukin 1 from macrophages cultured on different polyetherurethanes.

R. Nakaoka, T. Tsuchiya, A. Nakamura, 2000, Journal of biomedical materials research.

Correlations among chemical constituents, cytotoxicities and tissue responses: in the case of natural rubber latex materials.

K. Toyoda, Y. Ikarashi, M. Sato, 1990, Biomaterials.

Comparative studies by cell culture and in vivo implantation test on the toxicity of natural rubber latex materials.

K. Toyoda, Y. Ikarashi, M. Sato, 1992, Journal of biomedical materials research.

Cytotoxicity of medical materials sterilized with vapour-phase hydrogen peroxide.

Y. Ikarashi, T. Tsuchiya, A. Nakamura, 1995, Biomaterials.

Differences of draining lymph node cell proliferation among mice, rats and guinea pigs following exposure to metal allergens.

T. Tsuchiya, Y. Ikarashi, T. Tsuchiya, 1992, Toxicology.

Studies on in vitro evaluation for the biocompatibility of various biomaterials: inhibitory activity of various kinds of polymer microspheres on metabolic cooperation.

R. Nakaoka, T. Tsuchiya, A. Nakamura, 2001, Journal of biomedical materials research.

Neural differentiation of midbrain cells on various protein-immobilized polyethylene films.

T. Tsuchiya, R. Nakaoka, A. Nakamura, 2003, Journal of biomedical materials research. Part A.

Influence of irritants on lymph node cell proliferation and the detection of contact sensitivity to metal salts in the murine local lymph node assay

Y. Ikarashi, T. Tsuchiya, A. Nakamura, 1993, Contact dermatitis.

Evaluation of skin sensitization potential of nickel, chromium, titanium and zirconium salts using guinea-pigs and mice.

Y. Ikarashi, T. Tsuchiya, A. Nakamura, 1996, Biomaterials.

A sensitive mouse lymph node assay with two application phases for detection of contact allergens

T. Tsuchiya, Y. Ikarashi, A. Nakamura, 2005, Archives of Toxicology.

Evaluation of Allergic Potential of Rubber Products: Comparison of Sample Preparation Methods for the Testing of Polymeric Medical Devices

W. D. de Jong, T. Tsuchiya, K. Andersen, 2003 .

Evaluation of biocompatibility, based on quantitative determination of the vascular response induced by material implantation.

K. Toyoda, T. Tsuchiya, Y. Ikarashi, 1991, Journal of biomedical materials research.

Effect of vitamin E on contact sensitization responses induced by 2,4-dinitrochlorobenzene in mice.

K. Kikugawa, M. Beppu, Y. Ikarashi, 1998, Journal of nutritional science and vitaminology.

Studies on tumor-promoting activity of polyethylene: inhibitory activity of metabolic cooperation on polyethylene surfaces is markedly decreased by surface modification with collagen but not with RGDS peptide.

Y. Ikada, R. Nakaoka, T. Tsuchiya, 1997, Journal of biomedical materials research.

Improved sensitivity and decreased sample size in a cytotoxicity test for biomaterials: a modified colony microassay using a microplate and crystal violet staining.

Y. Ikarashi, T. Tsuchiya, A. Nakamura, 1994, Journal of applied biomaterials : an official journal of the Society for Biomaterials.

Contact sensitivity to Tinuvin® P in mice

T. Tsuchiya, Y. Ikarashi, T. Tsuchiya, 1994, Contact dermatitis.

Assessment of contact sensitivity of four thiourea rubber accelerators: comparison of two mouse lymph node assays with the guinea pig maximization test.

Y. Ikarashi, T. Tsuchiya, A. Nakamura, 1994, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[Cytotoxicity of chemicals used in household products: estimation of eye irritating potency of 25 chemicals tested during 1991-1996].

Y. Ikarashi, T. Tsuchiya, A. Nakamura, 1997, Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences.

Simultaneus development of MHW guidelines for biological evaluation of medical devices and ISO 10993-Report of 10 years activity of the Standardization Committee of JSBM

Akitada Nakamura, A. Nakamura, 1999 .

Studies on the tumor-promoting activity of biomaterials: inhibition of metabolic cooperation by polyetherurethane and silicone.

T. Tsuchiya, A. Nakamura, H. Hata, 1995, Journal of biomedical materials research.

Studies on the tumor-promoting activity of additives in biomaterials: inhibition of metabolic cooperation by phenolic antioxidants involved in rubber materials.

N. Miyata, Y. Ikarashi, K. Fukuhara, 1995, Journal of biomedical materials research.

Species differences between rats and mice in the teratogenic action of ethylenethiourea: in vivo/in vitro tests and teratogenic activity of sera using an embryonic cell differentiation system.

T. Tsuchiya, A. Nakamura, A. Takahashi, 1991, Toxicology and applied pharmacology.

Comparative studies of the toxicity of standard reference materials in various cytotoxicity tests and in vivo implantation tests.

K. Toyoda, N. Tanaka, Y. Ikarashi, 1993, Journal of applied biomaterials : an official journal of the Society for Biomaterials.

Chondrogenic Cellular Responses to Titanium and Zirconium Alloys in Vitro

H. Doi, T. Yoneyama, T. Tsuchiya, 1998 .

Effect of heat treatment of poly(L-lactide) on the response of osteoblast-like MC3T3-E1 cells.

Y. Ikarashi, T. Tsuchiya, A. Nakamura, 2000, Biomaterials.

Evaluation of contact sensitivity of rubber chemicals using the murine local lymph node assay

T. Tsuchiya, Y. Ikarashi, A. Nakamura, 1993, Contact dermatitis.

Detection of contact sensitivity of metal salts using the murine local lymph node assay.

Y. Ikarashi, Ikarashii Yoshiaki, T. Toshie, 1992, Toxicology letters.

Contact sensitivity of and cross-sensitivity between 2-(2'-hydroxy-5'-methylphenyl)benzotriazole (Tinuvin P) and 2-(2'-hydroxy-3'-tert-butyl-5'-methylphenyl)-5-chlorobenzotriazole (Tinuvin 326) evaluated by lymph node cell proliferation and ear swelling response in mice.

Y. Ikarashi, T. Tsuchiya, A. Nakamura, 1994, Toxicology letters.

Studies on the mechanisms of tumorigenesis induced by polyetherurethanes in rats: leachable and biodegradable oligomers involving the diphenyl carbamate structure acted as an initiator on the transformation of Balb 3T3 cells.

R. Nakaoka, T. Tsuchiya, A. Nakamura, 1996, Journal of biomedical materials research.

A new hypothesis: inhibitory potentials of the gap-junctional intercellular communication play an important role in the tumorigenesis induced by biomaterials

Ryusuke Nakaoka, Atsushi Takahara, H. Degawa, 1996, Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference.

Studies on the tumor-promoting activity of polyurethanes: depletion of inhibitory action of metabolic cooperation on the surface of a polyalkyleneurethane but not a polyetherurethane.

A. Takahara, S. Cooper, T. Tsuchiya, 1995, Journal of Biomedical Materials Research.

The inhibitory mechanism of gap junctional intercellular communication induced by polyethylene and the restorative effects by surface modification with various proteins.

R. Nakaoka, T. Tsuchiya, A. Nakamura, 2001, Journal of biomedical materials research.

In vivo tissue/biomaterials toxic responses: Correlation with cytotoxic potential but not cell attachment

K. Isama, T. Tsuchiya, Y. Ikarashi, 1994 .

Application of Sensitive Mouse Lymph Node Assay for Detection of Contact Sensitization Capacity of Dyes

T. Tsuchiya, Y. Ikarashi, A. Nakamura, 1996, Journal of applied toxicology : JAT.

Studies on the causes of tumorigenesis induced by the biomaterials

T. Tsuchiya, A. Nakamura, 1994 .

Activation of osteoblast-like MC3T3-E1 cell responses by poly(lactide).

Y. Ikarashi, T. Tsuchiya, A. Nakamura, 2000, Biological & pharmaceutical bulletin.

Comparison of three in vitro assays to determine the ocular toxicity of detergent, oil, and organic solvents

T. Tsuchiya, Y. Ikarashi, A. Nakamura, 1993 .