Z. Topçu

发表

Comparative cytochrome P450 ‐1A1, ‐2A6, ‐2B6, ‐2C, ‐2D6, ‐2E1, ‐3A5 and ‐4B1 expressions in human larynx tissue analysed at mRNA level

T. Kamataki, D. Sarıkaya, C. Bilgen, 2006, Biopharmaceutics & drug disposition.

The Yeast Two-hybrid System and Its Pharmaceutical Significance

K. Borden, Z. Topçu, 2000, Pharmaceutical Research.

Biological Activity of 1-Aryl-3-phenethylamino-1-propanone Hydrochlorides and 3-Aroyl-4-aryl-1-phenethyl-4-piperidinols on PC-3 Cells and DNA Topoisomerase I Enzyme

Bulbul Pandit, Pui-Kai Li, H. Gul, 2010, Zeitschrift für Naturforschung C - A Journal of Biosciences.

Mutant Telomeric Repeats in Yeast Can Disrupt the Negative Regulation of Recombination-Mediated Telomere Maintenance and Create an Alternative Lengthening of Telomeres-Like Phenotype

M. Mceachern, Z. Topçu, L. Bechard, 2008, Molecular and Cellular Biology.

Critical time point for apoptotic cell death in an experimental ischemia/reperfusion model and the effect of N-acetylcystein

M. Emre, A. Açıkalın, Z. Topçu, 2017 .

Abrupt disruption of capping and a single source for recombinationally elongated telomeres in Kluyveromyces lactis.

M. Mceachern, Z. Topçu, K. Nickles, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Detection of Cytochrome P450-2A6, -3A5 and -4B1 with Real-Time Polymerase Chain Reaction in Prostate Tissue

D. Alptekin, Z. Topçu, V. Caner, 2008, Zeitschrift fur Naturforschung. C, Journal of biosciences.

Cucurbit[7]uril Macrocyclic Sensors for Optical Fingerprinting: Predicting Protein Structural Changes to Identifying Disease-Specific Amyloid Assemblies.

Sarit S. Agasti, Y. Rozenholc, N. Gagey-Eilstein, 2022, Journal of the American Chemical Society.

Flavonoids in Helichrysum pamphylicum Inhibit Mammalian Type I DNA Topoisomerase

E. Kilinc, Z. Topçu, O. Kucukoglu, 2008, Zeitschrift fur Naturforschung. C, Journal of biosciences.

Inhibitory Activities of Helichrysum. Taxa on Mammalian Type I DNA Topoisomerase

T. Kamataki, Z. Topçu, O. Kucukoglu, 2006 .

Oxidative stress in relation to telomere length maintenance in vascular smooth muscle cells following balloon angioplasty

I. Oran, Z. Topçu, G. Gokce, 2010, Journal of Physiology and Biochemistry.

Telomeric restriction analysis of vascular smooth muscle cells following balloon angioplasty in rabbits

M. Tosun, B. Lebe, I. Oran, 2009, Journal of Physiology and Biochemistry.

Cytotoxic activity of 4′-hydroxychalcone derivatives against Jurkat cells and their effects on mammalian DNA topoisomerase I

M. Atalay, H. Gul, M. Gul, 2008, Journal of enzyme inhibition and medicinal chemistry.

Selected ellipticine derivatives, known to target topoisomerase II, suppress the alternative lengthening of telomere (ALT) pathway in telomerase–negative cells

Y. Ergun, S. Teng, Tsai-Kun Li, 2020, Journal of Cancer Research and Clinical Oncology.

Effects of Secondary Metabolites from the Fungus Septofusidium berolinense on DNA Cleavage Mediated by Human Topoisomerase IIα.

N. Osheroff, E. Bedir, Z. Topçu, 2016, Chemical research in toxicology.

Recombination Can either Help Maintain Very Short Telomeres or Generate Longer Telomeres in Yeast Cells with Weak Telomerase Activity

E. Basenko, Z. Topçu, M. McEachern, 2011, Eukaryotic Cell.

Imatinib‐induced apoptosis: a possible link to topoisomerase enzyme inhibition

Y. Baran, Z. Çakır, Z. Topçu, 2011, Journal of clinical pharmacy and therapeutics.

Anticancer and Multidrug Resistance-Reversal Effects of Solanidine Analogs Synthetized from Pregnadienolone Acetate

J. Molnár, L. Puskás, J. Molnár, 2014, Molecules.

Synthesis and biological activity evaluation of 1H-benzimidazoles via mammalian DNA topoisomerase I and cytostaticity assays.

I. Zupkó, G. Coban, Z. Topçu, 2008, European journal of medicinal chemistry.

DNA topoisomerases as targets for anticancer drugs

Z Topcu, Z. Topçu, 2001, Journal of clinical pharmacy and therapeutics.

Biological activity of bis-benzimidazole derivatives on DNA topoisomerase I and HeLa, MCF7 and A431 cells

I. Zupkó, G. Coban, A. S. Alpan, 2009, Journal of enzyme inhibition and medicinal chemistry.

Mammalian mitochondrial DNA topoisomerase I preferentially relaxes supercoils in plasmids containing specific mitochondrial DNA sequences.

F. Castora, Z. Topçu, Zeki Topcu, 1995, Biochimica et biophysica acta.

The Effects of Arolycoricidine and Narciprimine on Tumor Cell Killing and Topoisomerase Activity

I. Zupkó, J. Bastida, Z. Topçu, 2012 .

Identification of transcriptional and phosphatase regulators as interaction partners of human ADA3, a component of histone acetyltransferase complexes.

I. Boros, M. Dobson, F. Ayaydin, 2013, The Biochemical journal.

Identification of brain-specific angiogenesis inhibitor 2 as an interaction partner of glutaminase interacting protein.

S. Mohanty, M. Dobson, Monimoy Banerjee, 2011, Biochemical and biophysical research communications.

Inhibition of human DNA topoisomerase IIα by two novel ellipticine derivatives.

Sevil Zencir, Neil Osheroff, Yavuz Ergün, 2016, Bioorganic & medicinal chemistry letters.

The promyelocytic leukemia protein PML interacts with the proline-rich homeodomain protein PRH: a RING may link hematopoiesis and growth control

K. Borden, R. Hromas, David L. Mack, 1999, Oncogene.

Oxidative Stress and Apoptosis in Relation to Exposure to Magnetic Field

Sevil Zencir, Salih Cetiner, Ibrahim Kahraman, 2011, Cell Biochemistry and Biophysics.

Gossypol Interferes with Both Type I and Type II Topoisomerase Activities Without Generating Strand Breaks

Muge Senarisoy, Y. Baran, Z. Topçu, 2012, Cell Biochemistry and Biophysics.

Structural modification of ellipticine derivatives with alkyl groups of varying length is influential on their effects on human DNA topoisomerase II: a combined experimental and computational study

S. Durdağı, I. Zupkó, K. Sahin, 2019, Medicinal Chemistry Research.

Che1/AATF interacts with subunits of the histone acetyltransferase core module of SAGA complexes

I. Boros, Muge Senarisoy, M. Dobson, 2017, PloS one.

1H-Benzimidazole derivatives as mammalian DNA topoisomerase I inhibitors.

A. S. Alpan, Z. Topçu, H. Gunes, 2007, Acta biochimica Polonica.

New partner proteins containing novel internal recognition motif for human glutaminase interacting protein (hGIP).

S. Mohanty, M. Dobson, F. Ayaydin, 2013, Biochemical and biophysical research communications.

An optimized recipe for cloning of the polymerase chain reaction-amplified DNA inserts into plasmid vectors.

Z. Topçu, 2000, Acta biochimica Polonica.

Gossypol Interferes with Both Type I and Type II Topoisomerase Activities Without Generating Strand Breaks

Muge Senarisoy, Y. Baran, Z. Topçu, 2012, Cell Biochemistry and Biophysics.

Effect of some bis Mannich bases and corresponding piperidinols on DNA topoisomerase I.

H. Gul, M. Gul, Z. Topçu, 2008, Arzneimittel-Forschung.

New partner proteins containing novel internal recognition motif for human glutaminase interacting protein (hGIP).

S. Mohanty, M. Dobson, F. Ayaydin, 2013, Biochemical and biophysical research communications.