Ilka Mathar

发表

A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling.

P. Lipp, U. Laufs, M. Freichel, 2015, European heart journal.

Assessing the Use of the sGC Stimulator BAY-747, as a Potential Treatment for Duchenne Muscular Dystrophy

R. Seifert, A. Vakalopoulos, L. Dietz, 2021, International journal of molecular sciences.

Effects of Finerenone Combined with Empagliflozin in a Model of Hypertension-Induced End-Organ Damage

M. Pavkovic, F. Eitner, K. Droebner, 2021, American Journal of Nephrology.

Methylglyoxal evokes acute Ca2+ transients in distinct cell types and increases agonist-evoked Ca2+ entry in endothelial cells via CRAC channels.

M. Freichel, Dagmar Schumacher, V. Tsvilovskyy, 2019, Cell calcium.

Increased β‐adrenergic inotropy in ventricular myocardium from trpm4‐/‐ mice. (LB666)

M. Freichel, V. Flockerzi, R. Vennekens, 2014 .

New pulmonary hypertension model in conscious dogs to investigate pulmonary-selectivity of acute pharmacological interventions

P. Kolkhof, Philip Boehme, T. Mondritzki, 2017, European Journal of Applied Physiology.

Nitric Oxide‐Independent Soluble Guanylate Cyclase Activation Improves Vascular Function and Cardiac Remodeling in Sickle Cell Disease

M. Gladwin, J. Stasch, R. Vanderpool, 2017, American journal of respiratory cell and molecular biology.

Runcaciguat, a novel soluble guanylate cyclase activator, shows renoprotection in hypertensive, diabetic, and metabolic preclinical models of chronic kidney disease

J. Stasch, M. Pavkovic, F. Eitner, 2021, Naunyn-Schmiedeberg's Archives of Pharmacology.

TRPM4-mediated control of FcεRI-evoked Ca2+ elevation comprises enhanced plasmalemmal trafficking of TRPM4 channels in connective tissue type mast cells

P. Lipp, M. Freichel, A. Pfeifer, 2016, Scientific Reports.

Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice.

M. Freichel, V. Flockerzi, R. Vennekens, 2010, The Journal of clinical investigation.

Transient receptor potential M3 channels are ionotropic steroid receptors in pancreatic β cells

V. Flockerzi, S. Philipp, Annette Lis, 2008, Nature Cell Biology.

Control of Insulin Release by Transient Receptor Potential Melastatin 3 (TRPM3) Ion Channels.

A. Beck, M. Freichel, S. Philipp, 2020, Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.

Loss of smooth muscle CYB5R3 amplifies angiotensin-II induced hypertension by increasing sGC heme oxidation.

Megan P. Miller, Neha Hafeez, P. Sandner, 2019, JCI insight.

Loss of smooth muscle CYB 5 R 3 amplifies angiotensin-II induced hypertension by increasing sGC heme oxidation JCI Insight

Megan P. Miller, Neha Hafeez, P. Sandner, 2019 .

TRP Channels in the Heart

M. Freichel, L. Bacmeister, W. Frede, 2017 .

Increased IgE-dependent mast cell activation and anaphylactic responses in mice lacking the calcium-activated nonselective cation channel TRPM4

M. Freichel, V. Flockerzi, S. Philipp, 2007, Nature Immunology.

TRPC proteins contribute to development of diabetic retinopathy and regulate glyoxalase 1 activity and methylglyoxal accumulation

H. Hammes, M. Freichel, L. Birnbaumer, 2018, Molecular metabolism.

Heart Rate Contributes to the Vascular Effects of Chronic Mental Stress: Effects on Endothelial Function and Ischemic Brain Injury in Mice

M. Endres, U. Laufs, M. Freichel, 2011, Stroke.

Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory

Andreas Draguhn, Martin Both, Marc Freichel, 2017, The EMBO journal.

Treatment effects of soluble guanylate cyclase modulation on diabetic kidney disease at single-cell resolution

M. Pavkovic, F. Eitner, K. Suszták, 2023, Cell reports. Medicine.

Contractility Measurements on Isolated Papillary Muscles for the Investigation of Cardiac Inotropy in Mice.

M. Freichel, S. Uhl, Ilka Mathar, 2015, Journal of visualized experiments : JoVE.

Adenylyl cyclase-mediated effects contribute to increased Isoprenaline-induced cardiac contractility in TRPM4-deficient mice.

M. Freichel, R. Vennekens, S. Uhl, 2014, Journal of molecular and cellular cardiology.

Increased &bgr;-Adrenergic Inotropy in Ventricular Myocardium From Trpm4−/− Mice

M. Freichel, V. Flockerzi, R. Vennekens, 2014, Circulation research.

TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A

Hussein N. Rubaiy, H. Waldmann, M. Freichel, 2018, Oncotarget.

The sGC Activator Runcaciguat Has Kidney Protective Effects and Prevents a Decline of Kidney Function in ZSF1 Rats

M. Pavkovic, H. Ellinger-Ziegelbauer, F. Eitner, 2023, International journal of molecular sciences.

Increased &bgr;-Adrenergic Inotropy in Ventricular Myocardium From Trpm4−/− Mice

M. Freichel, V. Flockerzi, R. Vennekens, 2014, Circulation research.

New pulmonary hypertension model in conscious dogs to investigate pulmonary-selectivity of acute pharmacological interventions

P. Kolkhof, T. Mondritzki, H. Truebel, 2017, European Journal of Applied Physiology.

OCaR1 endows exocytic vesicles with autoregulatory competence by preventing uncontrolled Ca2+ release, exocytosis, and pancreatic tissue damage

N. Klugbauer, M. Biel, S. Muallem, 2024, The Journal of clinical investigation.