Narelle E. McGregor

发表

IL-6 exhibits both cis- and trans-signaling in osteocytes and osteoblasts, but only trans-signaling promotes bone formation and osteoclastogenesis

T. Martin, I. J. Poulton, N. Sims, 2019, The Journal of Biological Chemistry.

Dynll1 is essential for development and promotes endochondral bone formation by regulating intraflagellar Dynein function in primary cilia.

J. Heierhorst, N. Sims, I. Smyth, 2019, Human molecular genetics.

gp130 in late osteoblasts and osteocytes is required for PTH-induced osteoblast differentiation.

T. Martin, Rachelle W Johnson, I. J. Poulton, 2014, The Journal of endocrinology.

Dmp1Cre‐directed knockdown of parathyroid hormone–related protein (PTHrP) in murine decidua is associated with a life‐long increase in bone mass, width, and strength in male progeny

T. Martin, C. Kovacs, I. J. Poulton, 2021, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Dmp1Cre-directed knockdown of PTHrP in murine decidua is associated with increased bone width and a life-long increase in strength specific to male progeny

T. Martin, C. Kovacs, I. J. Poulton, 2020, bioRxiv.

The Primary Function of gp130 Signaling in Osteoblasts Is To Maintain Bone Formation and Strength, Rather Than Promote Osteoclast Formation

Rachelle W Johnson, I. J. Poulton, N. Sims, 2014, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Osteoclast Inhibitory Lectin, an Immune Cell Product That Is Required for Normal Bone Physiology in Vivo*

T. Martin, M. Smyth, I. J. Poulton, 2008, Journal of Biological Chemistry.

Germline deletion of AMP‐activated protein kinase β subunits reduces bone mass without altering osteoclast differentiation or function

B. Kemp, I. J. Poulton, N. Sims, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

G‐CSF Receptor Deletion Amplifies Cortical Bone Dysfunction in Mice With STAT3 Hyperactivation in Osteocytes

I. Wicks, N. Sims, Jonathan H. Gooi, 2022, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Bone corticalization requires local SOCS3 activity and is promoted by androgen action via interleukin-6

T. Martin, David Handelsman, Rachelle W Johnson, 2017, Nature Communications.

Ciliary Neurotrophic Factor Inhibits Bone Formation and Plays a Sex-Specific Role in Bone Growth and Remodeling

T. Martin, N. Sims, J. Quinn, 2010, Calcified Tissue International.

Cortical bone maturation in mice requires SOCS3 suppression of gp130/STAT3 signalling in osteocytes

T. Martin, N. Sims, E. C. Walker, 2020, eLife.

Contrasting roles of leukemia inhibitory factor in murine bone development and remodeling involve region‐specific changes in vascularization

N. Sims, E. C. Walker, S. Pompolo, 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Cardiotrophin‐1 Is an Osteoclast‐Derived Stimulus of Bone Formation Required for Normal Bone Remodeling

N. Sims, M. Gillespie, J. Quinn, 2008, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Osteopontin is An Important Regulative Component of the Fetal Bone Marrow Hematopoietic Stem Cell Niche

S. Heazlewood, S. Nilsson, Xuan Sun, 2019, Cells.

Calcitriol‐Dependent and ‐Independent Regulation of Intestinal Calcium Absorption, Osteoblast Function, and Skeletal Mineralization during Lactation and Recovery in Mice

C. Kovacs, N. Sims, Narelle E. McGregor, 2022, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

EphrinB2 signaling in osteoblasts promotes bone mineralization by preventing apoptosis

T. Martin, N. Sims, S. Tonna, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Granulocyte-CSF links destructive inflammation and comorbidities in obstructive lung disease

M. Maxwell, M. Hibbs, Daniel P Steinfort, 2018, The Journal of clinical investigation.

STAT3 Hyperactivation Due to SOCS3 Deletion in Murine Osteocytes Accentuates Responses to Exercise‐ and Load‐Induced Bone Formation

S. Windahl, N. Sims, E. C. Walker, 2021, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Bone corticalization requires local SOCS3 activity and is promoted by androgen action via interleukin-6

T. Martin, David Handelsman, Rachelle W Johnson, 2017, Nature Communications.

Bone Geometry Is Altered by Follistatin‐Induced Muscle Growth in Young Adult Male Mice

T. Martin, N. Sims, G. Lynch, 2021, JBMR plus.

Chondrocytic ephrin B2 promotes cartilage destruction by osteoclasts in endochondral ossification

T. Martin, N. Sims, S. Tonna, 2016, Development.

IL-6 trans-signalling mediates trabecular, but not cortical, bone loss after ovariectomy.

N. Sims, W. Ferlin, Narelle E. McGregor, 2018, Bone.

Oncostatin M promotes bone formation independently of resorption when signaling through leukemia inhibitory factor receptor in mice.

T. Martin, N. Sims, M. Gillespie, 2010, The Journal of clinical investigation.

Glycoprotein130 (Gp130)/interleukin-6 (IL-6) signalling in osteoclasts promotes bone formation in periosteal and trabecular bone.

T. Martin, Rachelle W Johnson, N. Sims, 2015, Bone.

Sustained RANKL response to parathyroid hormone in oncostatin M receptor‐deficient osteoblasts converts anabolic treatment to a catabolic effect in vivo

N. Sims, E. C. Walker, Julie M. Quach, 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Mice lacking AMP-activated kinase (AMPK) subunits β1 or β2 have low bone mass, while AICAR acts AMPK-independently to increase osteoclast formation

B. Kemp, N. Sims, M. Gillespie, 2009 .

The effect of carbamazepine on bone structure and strength in control and osteogenesis imperfecta (Col1a2 +/p.G610C ) mice

N. Sims, J. Bateman, L. Rowley, 2022, bioRxiv.

Measuring Bone Volume at Multiple Densities by Micro-computed Tomography.

N. Sims, E. C. Walker, Audrey S. M. Chan, 2021, Bio-protocol.

Testing Bone Formation Induction by Calvarial Injection Assay in vivo.

N. Sims, E. C. Walker, Narelle E. McGregor, 2020, Bio-protocol.

Bone corticalization requires local SOCS3 activity and is promoted by androgen action via interleukin-6

David Handelsman, N. Sims, Jonathan H. Gooi, 2017, Nature Communications.