N. Duverger

发表

Complete atherosclerosis regression after human ApoE gene transfer in ApoE-deficient/nude mice.

J. Caillaud, D. Branellec, J. Fruchart, 2000, Arteriosclerosis, thrombosis, and vascular biology.

Inhibition of atherosclerosis development in cholesterol-fed human apolipoprotein A-I-transgenic rabbits.

P. Denéfle, L. Houdebine, J. Caillaud, 1996, Circulation.

Increased levels of high-density lipoprotein cholesterol are ineffective in inhibiting the development of immune responses to oxidized low-density lipoprotein and atherosclerosis in transgenic rabbits expressing human apolipoprotein (apo) A-I with severe hypercholesterolaemia.

J. Caillaud, J. Fruchart, A. Tailleux, 2001, Clinical science.

17β-Estradiol Prevents Fatty Streak Formation in Apolipoprotein E–Deficient Mice

J. Arnal, J. Faye, C. Fiévet, 1997 .

REDD2 Gene Is Upregulated by Modified LDL or Hypoxia and Mediates Human Macrophage Cell Death

M. Jaye, A. Nègre-Salvayre, J. Fruchart, 2004, Arteriosclerosis, thrombosis, and vascular biology.

Atherosclerotic Lesions in Apolipoprotein E Adenovirus-Mediated Overexpression of Tissue Inhibitor of Metalloproteinase-1 Reduces

J. Caillaud, P. Horellou, P. Lesnik, 1999 .

Gene-based therapeutic strategies for Human Lipoprotein Lipase (LPL) deficiency: Rationale and prospects for alteration of atherogenic risk

B. McManus, M. Hayden, P. Denéfle, 1996 .

Lipoprotein A-I containing particles.

P. Duchateau, J. Fruchart, N. Théret, 1991, Advances in experimental medicine and biology.

Decreased Susceptibility to Diet-Induced Atherosclerosis in Human Apolipoprotein A-II Transgenic Mice

G. Luc, J. Caillaud, J. Fruchart, 2000, Arteriosclerosis, thrombosis, and vascular biology.

Cholesterol efflux, lecithin-cholesterol acyltransferase activity, and pre-beta particle formation by serum from human apolipoprotein A-I and apolipoprotein A-I/apolipoprotein A-II transgenic mice consistent with the latter being less effective for reverse cholesterol transport.

E. Rubin, P. Denéfle, J. Fruchart, 1997, Biochemistry.

Correction of hypertriglyceridemia and impaired fat tolerance in lipoprotein lipase-deficient mice by adenovirus-mediated expression of human lipoprotein lipase.

B. McManus, M. Hayden, P. Denéfle, 1997, Arteriosclerosis, thrombosis, and vascular biology.

Section Review: Cardiovascular & Renal: Genetic therapies for vascular diseases and lipid disorders

P. Denéfle, D. Branellec, N. Duverger, 1995 .

The ABCA1 transporter functions on the basolateral surface of hepatocytes.

H. Brewer, A. Remaley, C. Combs, 2002, Biochemical and biophysical research communications.

Antiangiogenic Effect of Interleukin-10 in Ischemia-Induced Angiogenesis in Mice Hindlimb

D. Scherman, M. Bureau, B. Lévy, 2000, Circulation research.

Lipoproteins containing apolipoprotein A-IV: composition and relation to cholesterol esterification.

J. Fruchart, N. Théret, G. Castro, 1994, Biochimica et biophysica acta.

Tangier disease: isolation and characterization of LpA-I, LpA-II, LpA-I: A-II and LpA-IV particles from plasma.

P. Duchateau, D. Rader, H. Brewer, 1993, Biochimica et biophysica acta.

Potential gene therapy for lecithin-cholesterol acyltransferase (LCAT)-deficient and hypoalphalipoproteinemic patients with adenovirus-mediated transfer of human LCAT gene.

G. Luc, E. Rubin, P. Denéfle, 1996, Circulation.

Protection Against Atherogenesis in Mice Mediated by Human Apolipoprotein A-IV

P. Denéfle, J. Caillaud, J. Fruchart, 1996, Science.

Characterization of apoA-IV-containing lipoprotein particles isolated from human plasma and interstitial fluid.

J. Fruchart, G. Castro, G. Ailhaud, 1993, Arteriosclerosis and thrombosis : a journal of vascular biology.

Paraoxonase activity is reduced by a pro-atherosclerotic diet in rabbits.

J. Caillaud, J. Fruchart, A. Tailleux, 2000, Biochemical and biophysical research communications.

Functional characterization of human recombinant apolipoprotein AIV produced in Escherichia coli.

J. Taylor, P. Denéfle, J. Mayaux, 1991, European journal of biochemistry.

Systemic tissue inhibitor of metalloproteinase‐1 gene delivery reduces neointimal hyperplasia in balloon‐injured rat carotid artery

K. Walsh, J. Fruchart, M. Rouis, 2002, FEBS letters.

Somatic gene transfer of human ApoA-I inhibits atherosclerosis progression in mouse models.

P. Denéfle, J. Caillaud, D. Branellec, 1999, Circulation.

Expression of Human Apolipoprotein A-I/C-III/A-IV Gene Cluster in Mice Induces Hyperlipidemia but Reduces Atherogenesis

N. Baroukh, J. Fruchart, L. Vergnes, 2000, Arteriosclerosis, thrombosis, and vascular biology.

Impairment of endothelium-dependent arterial relaxation by high-fat feeding in ApoE-deficient mice: toward normalization by human ApoA-I expression.

P. Gambert, G. Lizard, L. Lagrost, 1999, Circulation.

Displacement of apo A-I from HDL by apo A-II or its C-terminal helix promotes the formation of pre-beta1 migrating particles and decreases LCAT activation.

J. Vandekerckhove, M. Rosseneu, B. Vanloo, 1998, Atherosclerosis.

Endothelial derived vasorelaxation is impaired in human APO A-I transgenic rabbits.

P. Denéfle, J. Fruchart, G. Lebuffe, 1997, Biochemical and biophysical research communications.

Differential Interaction of the Human Cholesteryl Ester Transfer Protein with Plasma High Density Lipoproteins (HDLs) from Humans, Control Mice, and Transgenic Mice to Human HDL Apolipoproteins

L. Lagrost, D. Masson, D. Masson, 1997, The Journal of Biological Chemistry.

Transgenic rabbits expressing human apolipoprotein A-I in the liver.

P. Denéfle, B. Laine, J. Fruchart, 1996, Arteriosclerosis, thrombosis, and vascular biology.

Clearance of cationized LDL cholesterol from a muscle depot is not enhanced in human apolipoprotein A-IV transgenic mice.

O. Stein, Y. Stein, Y. Dabach, 2000, Arteriosclerosis, thrombosis, and vascular biology.

Efficient adenovirus-mediated ectopic gene expression of human lipoprotein lipase in human hepatic (HepG2) cells.

M. Hayden, P. Denéfle, D. Ginzinger, 1997, Human gene therapy.

Apolipoprotein(a) Yeast Artificial Chromosome Transgenic Rabbits

E. Rubin, E. Gong, P. Denéfle, 1998, The Journal of Biological Chemistry.

Adenovirus-mediated overexpression of tissue inhibitor of metalloproteinase-1 reduces atherosclerotic lesions in apolipoprotein E-deficient mice.

J. Caillaud, P. Horellou, P. Lesnik, 1999, Circulation.

Dupilumab in CRSwNP: Responder Analysis Using Clinically Meaningful Efficacy Outcome Thresholds

C. Bachert, W. Fokkens, I. Guillemin, 2021, The Laryngoscope.

Interaction of reconstituted high density lipoprotein discs containing human apolipoprotein A-I (ApoA-I) variants with murine adipocytes and macrophages. Evidence for reduced cholesterol efflux promotion by apoA-I(Pro165-->Arg).

P. Duchateau, A. von Eckardstein, G. Assmann, 1993, The Journal of biological chemistry.

PPAR-α and PPAR-γ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway

M. Jaye, H. Brewer, A. Remaley, 2001, Nature Medicine.

Characterization of the ABCA transporter subfamily: identification of prokaryotic and eukaryotic members, phylogeny and topology.

J. Vandekerckhove, P. Denéfle, M. Rosseneu, 2003, Journal of molecular biology.

Tissue-specific expression of the human gene for lecithin: cholesterol acyltransferase in transgenic mice alters blood lipids, lipoproteins and lipases towards a less atherogenic profile.

G. Luc, B. Staels, G. Olivecrona, 1995, European journal of biochemistry.

Therapeutic liver repopulation in a mouse model of hypercholesterolemia.

A. Kahn, A. Tedgui, C. Mitchell, 2000, Human molecular genetics.

High-level protein secretion into blood circulation after electric pulse-mediated gene transfer into skeletal muscle.

D. Scherman, A. Mahfoudi, F. Soubrier, 2000, Molecular therapy : the journal of the American Society of Gene Therapy.

Severe atherosclerosis and hypoalphalipoproteinemia in the staggerer mouse, a mutant of the nuclear receptor RORalpha.

G. Luc, N. Delhaye-bouchaud, J. Mariani, 1998, Circulation.

PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway.

M. Jaye, H. Brewer, A. Remaley, 2000, Nature medicine.

Protective role of interleukin-10 in atherosclerosis.

M. Bureau, V. Deleuze, D. Scherman, 1999, Circulation research.

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

J. Piette, G. Assmann, P. Denéfle, 1999, Nature Genetics.

Three arginine residues in apolipoprotein A-I are critical for activation of lecithin:cholesterol acyltransferase.

Hetal N. Patel, J. Vandekerckhove, C. Shoulders, 2001, Journal of lipid research.

Apolipoprotein A-I(R151C)Paris is defective in activation of lecithin:cholesterol acyltransferase but not in initial lipid binding, formation of reconstituted lipoproteins, or promotion of cholesterol efflux

A. von Eckardstein, G. Assmann, P. Cullen, 1999, Journal of Molecular Medicine.

Opposite regulation of human versus mouse apolipoprotein A-I by fibrates in human apolipoprotein A-I transgenic mice.

J. Auwerx, E. Rubin, A. Guillouzo, 1996, The Journal of clinical investigation.

Systemic Delivery of Murine IL-10 by Intramuscular Injection of Expression Plasmid

V. Deleuze, D. Scherman, M. Bureau, 1999 .

A proposed architecture for lecithin cholesterol acyl transferase (LCAT): Identification of the catalytic triad and molecular modeling

J. Tavernier, A. Verhee, M. Rosseneu, 1998, Protein science : a publication of the Protein Society.

Human ApoA-IV overexpression in transgenic mice induces cAMP-stimulated cholesterol efflux from J774 macrophages to whole serum.

J. Paul, N. Fournier, N. Moatti, 2000, Arteriosclerosis, thrombosis, and vascular biology.

The C-terminal helix of human apolipoprotein AII promotes the fusion of unilamellar liposomes and displaces apolipoprotein AI from high-density lipoproteins.

R. Brasseur, J. Vandekerckhove, D. Rouy, 1998, European journal of biochemistry.

In-Depth Haplotype Analysis of ABCA1 Gene Polymorphisms in Relation to Plasma ApoA1 Levels and Myocardial Infarction

D. Tregouet, A. Evans, C. Morrison, 2004, Arteriosclerosis, thrombosis, and vascular biology.

Characterization of functional residues in the interfacial recognition domain of lecithin cholesterol acyltransferase (LCAT).

R. Brasseur, J. Tavernier, J. Vandekerckhove, 1999, Protein Engineering.

Expression and activity of the nucleotide-binding domains of the human ABCA1 transporter.

J. Vandekerckhove, B. Christiaens, M. Rosseneu, 2004, Protein expression and purification.

In Vitro Expression of Structural Defects in the Lecithin-Cholesterol Acyltransferase Gene (*)

H. Klein, H. Brewer, S. Marcovina, 1995, The Journal of Biological Chemistry.

Effect of mutations of N- and C-terminal charged residues on the activity of LCAT.

J. Tavernier, J. Vandekerckhove, A. Verhee, 2001, Journal of lipid research.

Prevention of fatty streak formation of 17beta-estradiol is not mediated by the production of nitric oxide in apolipoprotein E-deficient mice.

V. Richard, J. Arnal, C. Fiévet, 1997, Circulation.

Characterization of Lipoprotein Particles Containing Apolipoprotein A-IV

P. Duchateau, J. Fruchart, G. Castro, 1993 .

Beneficial effects of fibrates on apolipoprotein A-I metabolism occur independently of any peroxisome proliferative response.

L. Madsen, R. Berge, B. Staels, 1999, Circulation.

17 beta-estradiol prevents fatty streak formation in apolipoprotein E-deficient mice.

J. Arnal, J. Faye, C. Fiévet, 1997, Arteriosclerosis, thrombosis, and vascular biology.

Two different allelic mutations in the lecithin:cholesterol acyltransferase (LCAT) gene resulting in classic LCAT deficiency: LCAT (tyr83-->stop) and LCAT (tyr156-->asn).

D. Rader, H. Klein, H. Brewer, 1993, Journal of lipid research.

Expression of Human Apolipoprotein A-I/C-III/A-IV Gene Cluster in Mice Induces Hyperlipidemia but Reduces Atherogenesis

J. Najib, M. Nanjee, N. Duverger, 2000, Arteriosclerosis, thrombosis, and vascular biology.