Z. Ye

发表

Structure–activity relationship of linear tetrapeptides Tic-DPhe-Arg-Trp-NH2 at the human melanocortin-4 receptor and effects on feeding behaviors in rat

D. Macintyre, A. Patchett, R. Nargund, 2005, Peptides.

Chapter 4. Melanocortin-4 receptor agonists and antagonists: Chemistry and potential therapeutic utilities

M. Bednarek, R. Nargund, T. Fong, 2003 .

Melanocortin subtype 4 receptor agonists: structure-activity relationships about the 4-alkyl piperidine core.

L. V. D. van der Ploeg, A. Patchett, R. Nargund, 2007, Bioorganic & medicinal chemistry letters.

Contributions and mechanisms of components in modified biochar to adsorb cadmium in aqueous solution.

Q. Huang, Hui Li, Zhongxin Tan, 2020, The Science of the total environment.

Stimulation of Glucose-Dependent Insulin Secretion by a Potent, Selective sst3 Antagonist.

Margaret S. Wu, Yun-ping Zhou, A. Howard, 2012, ACS medicinal chemistry letters.

Spiroindane based amides as potent and selective MC4R agonists for the treatment of obesity.

Howard Y. Chen, R. Nargund, M. Wyvratt, 2010, Bioorganic & medicinal chemistry letters.

Discovery of highly potent and efficacious MC4R agonists with spiroindane N-Me-1,2,4-triazole privileged structures for the treatment of obesity.

M. Reibarkh, Howard Y. Chen, R. Nargund, 2010, Bioorganic & medicinal chemistry letters.

Discovery of potent, selective, and orally bioavailable 3H-spiro[isobenzofuran-1,4'-piperidine] based melanocortin subtype-4 receptor agonists.

D. Macintyre, Howard Y. Chen, R. Nargund, 2010, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of potent and orally bioavailable tert-butylpyrrolidine archetype derived melanocortin subtype-4 receptor modulators.

J. Huber, F. Ujjainwalla, L. V. D. van der Ploeg, 2008, Bioorganic & medicinal chemistry letters.

Development of a carbon-based slow release fertilizer treated by bio-oil coating and study on its feedback effect on farmland application

Q. Huang, Zhongxin Tan, Limei Zhang, 2019 .

Effects of pyrolysis conditions on migration and distribution of biochar nitrogen in the soil-plant-atmosphere system.

Q. Huang, Liyun Liu, Zhongxin Tan, 2020, The Science of the total environment.

Investigation of Cardiovascular Effects of Tetrahydro-β-carboline sstr3 antagonists.

Margaret S. Wu, M. Reibarkh, Yun-ping Zhou, 2014, ACS medicinal chemistry letters.

Transformation and Transport Mechanism of Nitrogenous Compounds in a Biochar “Preparation–Returning to the Field” Process Studied by Employing an Isotope Tracer Method

Liyun Liu, Zhongxin Tan, Z. Ye, 2018 .

Catalytic asymmetric hydrogenation to access spiroindane dimethyl acetic acid

R. Nargund, Z. Ye, Shuwen He, 2011 .

Discovery of a spiroindane based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor agonist.

D. Macintyre, Howard Y. Chen, R. Nargund, 2010, Bioorganic & medicinal chemistry letters.

Modeling directed design and biological evaluation of quinazolinones as non-peptidic growth hormone secretagogues.

A. Howard, S. Feighner, S. Pong, 2000, Bioorganic & Medicinal Chemistry Letters.

Development of a pharmaceutical cocrystal of a monophosphate salt with phosphoric acid.

Alex M. Chen, R. Ball, D. Mathre, 2007, Chemical communications.

Highly Efficient Synthesis of the Potent Antitumor Annonaceous Acetogenin (+)-Parviflorin

T. Hoye, Z. Ye, 1996 .

Synthesis of the C2-symmetric, macrocyclic alkaloid, (+)-xestospongin A and its C(9)-epimer, (-)-xestospongin C: Impact of substrate rigidity and reaction conditions on the efficiency of the macrocyclic dimerization reaction

T. Hoye, Z. Ye, J. North, 1996 .

Highly Efficient Synthesis of the Potent Antitumor Annonaceous Acetogenin (+)-Parviflorin.

T. Hoye, Z. Ye, 1996 .

An efficient and versatile synthesis of the butenolide subunit of 4-hydroxylated annonaceous acetogenins

T. Hoye, L. Tan, Z. Ye, 1994 .

Synthesis of novel D-seco-taxoids derived from 1-deoxybaccatin VI

J. Shao, Z. Ye, Haixia Lin, 2010 .

The Discovery of MK-4256, a Potent SSTR3 Antagonist as a Potential Treatment of Type 2 Diabetes.

Margaret S. Wu, Rebecca T. Ruck, M. Reibarkh, 2012, ACS medicinal chemistry letters.

Dynamic cross-linked polyurethane hot-melt adhesive with high biomass content and high adhesive strength simultaneously

Qingwen Wang, Rongxian Ou, Zhenzhen Liu, 2022, European Polymer Journal.

Discovery and activity of (1R,4S,6R)-N-[(1R)-2-[4-cyclohexyl-4-[[(1,1-dimethylethyl)amino]carbonyl]-1-piperidinyl]-1-[(4-fluorophenyl)methyl]-2-oxoethyl]-2-methyl-2-azabicyclo[2.2.2]octane-6-carboxamide (3, RY764), a potent and selective melanocortin subtype-4 receptor agonist.

J. Metzger, D. Macintyre, L. V. D. van der Ploeg, 2005, Bioorganic & Medicinal Chemistry Letters.

Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist.

D. Macintyre, Howard Y. Chen, R. Nargund, 2011, Bioorganic & medicinal chemistry letters.

Optimization of privileged structures for selective and potent melanocortin subtype-4 receptor ligands.

J. Metzger, L. V. D. van der Ploeg, C. Rosenblum, 2010, Bioorganic & medicinal chemistry letters.

1-Amino-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid as a Tic mimetic: application in the synthesis of potent human melanocortin-4 receptor selective agonists.

L. V. D. van der Ploeg, A. Patchett, R. Nargund, 2005, Bioorganic & medicinal chemistry letters.

SAR exploration at the C-3 position of tetrahydro-β-carboline sstr3 antagonists.

Margaret S. Wu, M. Reibarkh, Yun-ping Zhou, 2016, Bioorganic & medicinal chemistry letters.

Discovery of MK-1421, a Potent, Selective sstr3 Antagonist, as a Development Candidate for Type 2 Diabetes

Margaret S. Wu, Yun-ping Zhou, E. Sherer, 2015, ACS medicinal chemistry letters.

Design and pharmacology of N-[(3R)-1,2,3,4-tetrahydroisoquinolinium- 3-ylcarbonyl]-(1R)-1-(4-chlorobenzyl)- 2-[4-cyclohexyl-4-(1H-1,2,4-triazol- 1-ylmethyl)piperidin-1-yl]-2-oxoethylamine (1), a potent, selective, melanocortin subtype-4 receptor agonist.

D. Johnston, D. Macintyre, L. V. D. van der Ploeg, 2002, Journal of medicinal chemistry.

Discovery of AG-270, a First-in-Class Oral MAT2A Inhibitor for the Treatment of Tumors with Homozygous MTAP Deletion.

K. Marks, S. Gross, B. Delabarre, 2021, Journal of medicinal chemistry.

Discovery of (2S)-N-[(1R)-2-[4-cyclohexyl-4-[[(1,1-dimethylethyl)amino]carbonyl]-1-piperidinyl]-1-[(4-fluorophenyl)methyl]-2-oxoethyl]-4-methyl-2-piperazinecarboxamide (MB243), a potent and selective melanocortin subtype-4 receptor agonist.

J. Metzger, D. Macintyre, L. V. D. van der Ploeg, 2005, Bioorganic & medicinal chemistry letters.

Modeling Directed Design and Biological Evaluation of Quinazolinones as Non‐peptidic Growth Hormone Secretagogues.

Z. Ye, 2000 .

Orexigenic action of peripheral ghrelin is mediated by neuropeptide Y and agouti-related protein.

D. Macneil, Roy G. Smith, S. Qian, 2004, Endocrinology.

Application of the 15N tracer method to study the effect of pyrolysis temperature and atmosphere on the distribution of biochar nitrogen in the biomass-biochar-plant system.

Zhongxin Tan, Limei Zhang, Z. Ye, 2018, The Science of the total environment.

Spiroindane based amides as potent and selective MC4R agonists for the treatment of obesity.

Howard Y. Chen, R. Nargund, M. Wyvratt, 2010, Bioorganic & Medicinal Chemistry Letters.