David L. Williams

发表

Changes in Plasma Membrane Properties and Phosphatidylcholine Subspecies of Insect Sf9 Cells Due to Expression of Scavenger Receptor Class B, Type I, and CD36*

Seth M. Klein, M. Connelly, C. Iden, 2004, Journal of Biological Chemistry.

Isolation and characterization of a cDNA clone specific for avian viteDogenin II

G. S. Shelness, P. Ostapchuk, A. Protter, 2005 .

Scavenger receptor class B Type I (SR-BI) assembles into detergent-sensitive dimers and tetramers.

M. Connelly, David L. Williams, D. Sahoo, 2007, Biochimica et biophysica acta.

Apolipoprotein A-I Is Necessary for thein Vivo Formation of High Density Lipoprotein Competent for Scavenger Receptor BI-mediated Cholesteryl Ester-selective Uptake*

R. Walzem, R. Temel, C. Banka, 2002, The Journal of Biological Chemistry.

Separation of Lipid Transport Functions by Mutations in the Extracellular Domain of Scavenger Receptor Class B, Type I*

M. Connelly, G. Rothblat, M. de la Llera-Moya, 2003, Journal of Biological Chemistry.

Scavenger receptor BI: A scavenger receptor with a mission to transport high density lipoprotein lipids

M. Connelly, David L. Williams, 2004, Current opinion in lipidology.

Cholesterol binding, efflux, and a PDZ-interacting domain of scavenger receptor-BI mediate HDL-initiated signaling.

M. Connelly, Y. Marcel, C. Mineo, 2005, The Journal of clinical investigation.

Scavenger Receptor Class B Type I-mediated Cholesteryl Ester-selective Uptake and Efflux of Unesterified Cholesterol

M. Connelly, M. Phillips, G. Rothblat, 2004, Journal of Biological Chemistry.

Enhancement of Scavenger Receptor Class B Type I-mediated Selective Cholesteryl Ester Uptake fromapoA-I−/− High Density Lipoprotein (HDL) by Apolipoprotein A-I Requires HDL Reorganization by Lecithin Cholesterol Acyltransferase*

J. Parks, R. Temel, David L. Williams, 2003, The Journal of Biological Chemistry.

Selecting selective suppressors of selective uptake.

David L. Williams, 2003, Chemistry & biology.

A quantitative analysis of apolipoprotein binding to SR-BI: multiple binding sites for lipid-free and lipid-associated apolipoproteins.

G. Anantharamaiah, M. Phillips, S. Lund-Katz, 2003, Journal of lipid research.

Binding and Cross-linking Studies Show That Scavenger Receptor BI Interacts with Multiple Sites in Apolipoprotein A-I and Identify the Class A Amphipathic α-Helix as a Recognition Motif*

M. Connelly, G. Anantharamaiah, M. Phillips, 2000, The Journal of Biological Chemistry.

High Density Lipoprotein Phospholipid Composition Is a Major Determinant of the Bi-directional Flux and Net Movement of Cellular Free Cholesterol Mediated by Scavenger Receptor BI*

W. J. Johnson, Seth M. Klein, P. Monzo, 2000, The Journal of Biological Chemistry.

Caveolin-1 does not affect SR-BI-mediated cholesterol efflux or selective uptake of cholesteryl ester in two cell lines Published, JLR Papers in Press, January 16, 2003. DOI 10.1194/jlr.M200449-JLR200

Hsu-hsin Chen, M. Connelly, A. Ostermeyer, 2003, Journal of Lipid Research.

Scavenger Receptor Class B, Type I, Mediates Selective Uptake of Low Density Lipoprotein Cholesteryl Ester*

M. Connelly, R. Temel, S. Swarnakar, 1999, The Journal of Biological Chemistry.

In vivo modulation of HDL phospholipid has opposing effects on SR-BI- and ABCA1-mediated cholesterol efflux Published, JLR Papers in Press, November 1, 2003. DOI 10.1194/jlr.M300231-JLR200

D. Rader, M. Connelly, P. Yancey, 2004, Journal of Lipid Research.

Glycine 420 Near the C-terminal Transmembrane Domain of SR-BI Is Critical for Proper Delivery and Metabolism of High Density Lipoprotein Cholesteryl Ester*

M. Connelly, Saj Parathath, G. Rothblat, 2004, Journal of Biological Chemistry.

SR‐BI and HDL Cholesteryl Ester Metabolism

M. Connelly, David L. Williams, 2004, Endocrine research.

SR-BI and cholesterol uptake into steroidogenic cells

M. Connelly, David L. Williams, 2003, Trends in Endocrinology & Metabolism.

SR-BI-directed HDL-cholesteryl ester hydrolysis Published, JLR Papers in Press, November 16, 2002. DOI 10.1194/jlr.M200186-JLR200

M. Connelly, G. Rothblat, David L. Williams, 2003, Journal of Lipid Research.

SR-BI-directed HDL-cholesteryl ester hydrolysis

M. Connelly, G. Rothblat, David L. Williams, 2003 .

Mechanism of Scavenger Receptor Class B Type I-mediated Selective Uptake of Cholesteryl Esters from High Density Lipoprotein to Adrenal Cells*

R. Temel, W. Rodrigueza, S. Lund-Katz, 1999, The Journal of Biological Chemistry.

SR-BI- and ABCA1-mediated cholesterol efflux to serum from patients with Alagille syndrome Published, JLR Papers in Press, June 21, 2004. DOI 10.1194/jlr.M400133-JLR200

M. Connelly, N. Stettler, P. Yancey, 2004, Journal of Lipid Research.

Analysis of Apolipoprotein E Function in Adrenal Cells: Effects on Cholesterol Metabolism and Signal Transduction Pathways

M. Reyland, J. Gwynne, M. Prack, 1993 .

Synthesis of Apolipoprotein E by Peripheral Tissues

P. Dawson, L. Rudel, T. Newman, 1985 .

Stabilization of caveolin-1 by cellular cholesterol and scavenger receptor class B type I.

M. Connelly, Y. Marcel, M. Lisanti, 2002, Biochemistry.

Differential expression of apolipoprotein E messenger RNA within the rat liver lobule determined by in situ hybridization

M. Massimi, S. Erickson, S. Lear, 1999, Hepatology.

Testing the role of apoA-I, HDL, and cholesterol efflux in the atheroprotective action of low-level apoE expression Published, JLR Papers in Press, September 1, 2003. DOI 10.1194/jlr.M300224-JLR200

P. Yancey, L. Rudel, G. Rothblat, 2003, Journal of Lipid Research.

Apolipoprotein E is the major physiological activator of lecithin-cholesterol acyltransferase (LCAT) on apolipoprotein B lipoproteins.

K. Weisgraber, J. Parks, Yue Zhao, 2005, Biochemistry.

Modification of Extracellular Matrix by the Product of DHA Oxidation Switches Macrophage Adhesion Patterns and Promotes Retention of Macrophages During Chronic Inflammation

E. Podrez, T. Byzova, V. Yakubenko, 2022, Frontiers in Immunology.

SR-BI is required for microvillar channel formation and the localization of HDL particles to the surface of adrenocortical cells in vivo.

J. Wong, R. Hamilton, David L. Williams, 2002, Journal of lipid research.

Oteromycin: A Novel Antagonist of Endothelin Receptor

G. Bills, R. Giacobbe, Sheo B. Singh, 1995 .

Class B scavenger receptor-mediated intestinal absorption of dietary beta-carotene and cholesterol.

H. Hauser, Chang-Hoon Han, M. Phillips, 2005, Biochemistry.

Purification of avian vitellogenin III: comparison with vitellogenins I and II

David L. Williams, Shouyue Wang, David W. E. Smith, 1983 .

The Apolipoprotein E-dependent Low Density Lipoprotein Cholesteryl Ester Selective Uptake Pathway in Murine Adrenocortical Cells Involves Chondroitin Sulfate Proteoglycans and an α2-Macroglobulin Receptor*

D. Strickland, J. Beers, S. Swarnakar, 2001, The Journal of Biological Chemistry.

Estrogen Induces the Assembly of a Multiprotein Messenger Ribonucleoprotein Complex on the 3′-Untranslated Region of Chicken Apolipoprotein II mRNA (*)

David L. Williams, J. Margot, 1996, The Journal of Biological Chemistry.

Inducible expression of protein kinase Cα suppresses steroidogenesis in Y-1 adrenocortical cells.

E. K. White, M. Reyland, David L. Williams, 1998, American journal of physiology. Cell physiology.

Altered Gene Expression in Early Atherosclerosis Is Blocked by Low Level Apolipoprotein E

C. Malbon, David L. Williams, F. Thorngate, 2008, PloS one.

A Test of the Cytosolic Apolipoprotein E Hypothesis Fails to Detect the Escape of Apolipoprotein E from the Endocytic Pathway into the Cytosol and Shows that Direct Expression of Apolipoprotein E in the Cytosol is Cytotoxic

R. Demattos, David L. Williams, F. Thorngate, 1999, The Journal of Neuroscience.

Scavenger receptor BI (SR-BI) clustered on microvillar extensions suggests that this plasma membrane domain is a way station for cholesterol trafficking between cells and high-density lipoprotein.

M. Connelly, M. Phillips, S. Lund-Katz, 2003, Molecular biology of the cell.

Scavenger Receptor Class B, Type I-mediated Uptake of Various Lipids into Cells

M. Phillips, Michael C. Phillips, Sissel Lund-Katz, 2001, The Journal of Biological Chemistry.

Subphysiologic Apolipoprotein E (ApoE) Plasma Levels Inhibit Neointimal Formation After Arterial Injury in ApoE-Deficient Mice

E. Fisher, J. Fallon, L. Rolnitzky, 2004, Arteriosclerosis, thrombosis, and vascular biology.

Roles of Scavenger Receptor Bi and APO A-I in Selective Uptake of Hdl Cholesterol by Adrenal Cells

M. Connelly, R. Temel, D. Williams, 2000, Endocrine research.

Independent effects of APOE on cholesterol metabolism and brain Abeta levels in an Alzheimer disease mouse model.

S. Fujita, K. Mann, B. Lamb, 2004, Human molecular genetics.

Selective Uptake of Low Density Lipoprotein-Cholesteryl Ester Is Enhanced by Inducible Apolipoprotein E Expression in Cultured Mouse Adrenocortical Cells*

M. Reyland, S. Swarnakar, S. Azhar, 1998, The Journal of Biological Chemistry.

Epidermal Keratinocytes Secrete Apolipoprotein E a

D. Williams, D. Gordon, L. Taichman, 1988, Annals of the New York Academy of Sciences.

Regulation by Adrenocorticotropic Hormone of the in Vivo Expression of Scavenger Receptor Class B Type I (SR-BI), a High Density Lipoprotein Receptor, in Steroidogenic Cells of the Murine Adrenal Gland*

E. Edelman, A. Rigotti, P. Seifert, 1996, The Journal of Biological Chemistry.

A Minimally Lipidated Form of Cell-derived Apolipoprotein E Exhibits Isoform-specific Stimulation of Neurite Outgrowth in the Absence of Exogenous Lipids or Lipoproteins*

R. Demattos, L. Curtiss, David L. Williams, 1998, The Journal of Biological Chemistry.

Comparison of Class B Scavenger Receptors, CD36 and Scavenger Receptor BI (SR-BI), Shows That Both Receptors Mediate High Density Lipoprotein-Cholesteryl Ester Selective Uptake but SR-BI Exhibits a Unique Enhancement of Cholesteryl Ester Uptake*

Seth M. Klein, M. Connelly, N. Abumrad, 1999, The Journal of Biological Chemistry.

Effects of amino acid substitutions at glycine 420 on SR-BI cholesterol transport function Published, JLR Papers in Press, March 19, 2007.

M. Connelly, Saj Parathath, M. Phillips, 2007, Journal of Lipid Research.

Correcting Hypercholesterolemia in ApoE-Deficient Mice Low Levels of Extrahepatic Nonmacrophage ApoE Inhibit Atherosclerosis Without

R. Walzem, L. Rudel, David L. Williams, 2000 .

Lipoproteins, HDL/LDL

David L. Williams, F. Thorngate, 2004 .

Cell cholesterol efflux: integration of old and new observations provides new insights.

M C Phillips, D. Williams, G H Rothblat, 1999, Journal of lipid research.

Sarafotoxin S6c: an agonist which distinguishes between endothelin receptor subtypes.

K. Jones, Kathryn L. Jones, D. Williams, 1991, Biochemical and biophysical research communications.

Differential effects of dietary fat on the tissue-specific expression of the apolipoprotein A-I gene: relationship to plasma concentration of high density lipoproteins.

L. Rudel, D. Williams, M. Sorci-Thomas, 1989, Journal of lipid research.

Characterization of the human cysteinyl leukotriene CysLT1 receptor

Jilly F. Evans, C. Austin, B. Connolly, 1999, Nature.

Low levels of extrahepatic nonmacrophage ApoE inhibit atherosclerosis without correcting hypercholesterolemia in ApoE-deficient mice.

R. Walzem, L. Rudel, D. Williams, 2000, Arteriosclerosis, thrombosis, and vascular biology.

Scavenger receptor class B, type I (SR-BI) is the major route for the delivery of high density lipoprotein cholesterol to the steroidogenic pathway in cultured mouse adrenocortical cells.

M. Krieger, B. Trigatti, R. Demattos, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Apolipoprotein A-I is required for cholesteryl ester accumulation in steroidogenic cells and for normal adrenal steroid production.

J. Breslow, A. Plump, D. Williams, 1996, The Journal of clinical investigation.

Scavenger receptor class B type I affects cholesterol homeostasis by magnifying cholesterol flux between cells and HDL.

Seth M. Klein, M. Connelly, E. Favari, 2001, Journal of lipid research.

Expression of scavenger receptor BI in COS-7 cells alters cholesterol content and distribution.

M. Connelly, D. Williams, G. Rothblat, 2000, Biochemistry.

Induction of cellular cholesterol efflux to lipid-free apolipoprotein A-I by cAMP.

D. Williams, M. Phillips, Genevieve W. Stoudt, 1999, Biochimica et biophysica acta.

Systemic distribution of apolipoprotein E secreted by grafts of epidermal keratinocytes: implications for epidermal function and gene therapy.

D. Gordon, L. Pershing, D. Williams, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Scavenger receptor BI and cholesterol trafficking.

M. Connelly, R. Temel, D. Williams, 1999, Current opinion in lipidology.

Scavenger receptor BI (SR-BI) mediates free cholesterol flux independently of HDL tethering to the cell surface.

M. Connelly, D. Williams, M. Phillips, 1999, Journal of lipid research.

Altered adrenal gland cholesterol metabolism in the apoE-deficient mouse Published, JLR Papers in Press, August 16, 2002. DOI 10.1194/jlr.M200205-JLR200

S. Erickson, David L. Williams, F. Thorngate, 2002, Journal of Lipid Research.

Altered Adrenal Gland Cholesterol Metabolism in the Apolipoprotein E-deficient Mouse*

S. Erickson, David L. Williams, F. Thorngate, 2002 .

Analysis of chimeric receptors shows that multiple distinct functional activities of scavenger receptor, class B, type I (SR-BI), are localized to the extracellular receptor domain.

Seth M. Klein, P. Monzo, M. Connelly, 2001, Biochemistry.

Regulation of chicken apolipoprotein B: cloning, tissue distribution, and estrogen induction of mRNA.

K. Svenson, T. Kirchgessner, D. Gordon, 1987, Gene.

Hsu-hsin Chen, M. Connelly, A. Ostermeyer, 2003, Journal of Lipid Research.