A. Villegas

发表

Glutathione S-transferase M1 and T1 genetic polymorphisms are not related to the risk of hepatocellular carcinoma: a study in the Spanish population.

M. Díaz‐Rubio, E. García-Martín, J. Agúndez, 2006, European journal of cancer.

Improving safety in blood transfusion using failure mode and effect analysis

Rafael Bielza, A. Villegas, A. Mora, 2019, Transfusion.

Presence of acute and chronic renal failure in patients with paroxysmal nocturnal hemoglobinuria: results of a retrospective analysis from the Spanish PNH Registry

S. Brunet, A. Gaya, B. Arrizabalaga, 2017, Annals of Hematology.

Spanish consensus statement for diagnosis and treatment of paroxysmal nocturnal haemoglobinuria

E. Colado, A. Órfão, V. Vicente, 2016 .

Hb Moncloa: A new variant of haemoglobin that interferes in the quantification of Hb A1c.

N. V. Ortiz-Cabrera, P. Ropero, A. Villegas, 2017, Clinical biochemistry.

Hemoglobin Seville [α2 β2 81(EF5) Leu→Phe] a silent phenotypic variant that interferes in hemoglobin A1c measurement by ion-exchange HPLC method.

J. Guerrero, A. Villegas, Teresa Herrera del Rey, 2011, Clinical biochemistry.

Does size matter? Two new deletions in the HBB gene cause β0-thalassemia

M. Sarasa, P. Ropero, M. J. Murúzabal, 2022, Annals of Hematology.

Why is the novel Hb Miguel Servet visualised by CE-HPLC newborn and not by the CE-HPLC β-thalassaemia programme?

P. Ropero, Guillermo Hernández de Abajo, C. Rodríguez-Vigil, 2020, Journal of Clinical Pathology.

Characterization of a New α-Thalassemia-1 Mutation in a Spanish Family

D. Espinós, A. Villegas, F. González, 1989 .

Glutathione S-transferases π1, α1 and µ3 genetic polymorphisms and the risk of hepatocellular carcinoma in humans

M. Díaz‐Rubio, E. García-Martín, J. Agúndez, 2007 .

Nondeletional α‐thalassemia in a Spanish population

A. Villegas, F. González, J. Sanchez, 1997 .

Incidence of the HFE gene mutations in a cohort of non-Spanish origin neonates in Madrid

M. Mateo, P. Ropero, O. Briceño, 2007, Annals of Hematology.

Novel nonsense mutation in the α1-globin gene [HBA1:C.49A>T] is responsible for non-deletion α-thalassemia.

P. Ropero, A. Villegas, F. González, 2019, Clinical biochemistry.

A Case of HB J-Chicago [β76(E20)ALAASP] in a Spanish Family

A. Erkiaga, B. Arrizabalaga, A. Villegas, 1998 .

Frequency of the C282Y and H63D mutations of the hemochromatosis gene (HFE) in a cohort of 1,000 neonates in Madrid (Spain)

M. Mateo, P. Ropero, O. Briceño, 2006, Annals of Hematology.

Extravascular hemolysis and complement consumption in Paroxysmal Nocturnal Hemoglobinuria patients undergoing eculizumab treatment.

S. Rodríguez de Córdoba, M. López-Trascasa, A. Villegas, 2017, Immunobiology.

Paroxysmal nocturnal hemoglobinuria: a single Spanish center’s experience over the last 40 yr

D. Morillo, J. Steegmann, M. Pastrana, 2014, European journal of haematology.

THE THALASSEMIA SYNDROMES: MOLECULAR CHARACTERIZATION IN THE SPANISH POPULATION

E. Anguita, D. Espinós, P. Ropero, 2001, Hemoglobin.

A Search for Anomalies in the ζ,α,β, and γ Globin Gene Arrangements in Normal Black, Italian, Turkish, and Spanish Newborns

Y. Fei, T. Huisman, G. Schilirò, 1989 .

MYELOFIBROSIS IN PRIMARY MYELODYSPLASTIC SYNDROMES

I. Krsnik, M. Rubio, A. Villegas, 1989, British journal of haematology.

Abnormally low HbA1c secondary to hemoglobin J-Baltimore [beta 16(A13) Gly-->Asp]. Family study.

M. Gargallo, A. Villegas, F. González, 2010, Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion.

Development and validation of a multivariable prediction rule for detecting a severe acquired ADAMTS13 activity deficiency in patients with thrombotic microangiopathies

P. Ropero, A. Villegas, M. Fuentes, 2017, Clinical chemistry and laboratory medicine.

Phenotype of mutations in the promoter region of the β-globin gene

B. Arrizabalaga, P. Ropero, M. Torrejón, 2017, Journal of Clinical Pathology.

Hb Nunobiki (α 2 141(HC3) Arg→Cys; HBA2:c.424C>T) in Spain: Mutation de novo or Acquired?

P. Ropero, A. Villegas, F. González, 2013 .

Association in Cis of the Mutations +20 (C>T) in the 5′ Untranslated Region and IVS-II-745 (C>G) on the β-Globin Gene

Á. Cervera, C. Beléndez, P. Ropero, 2013, Hemoglobin.

Haemoglobinopathies with high oxygen affinity. Experience of Erythropathology Cooperative Spanish Group

E. Anguita, P. Ropero, A. Villegas, 2009, Annals of Hematology.

Hemoglobina Stanleyville II [ α78(EF7)Asn → Lys]. Primer caso descrito en España

P. Ropero, A. Villegas, F. González, 2008 .

Origin of the Frameshift Codons 41/42 (–TCTT) Mutation in the First Cases Described in the Spanish Population

P. Ropero, A. Villegas, F. Ataúlfo González, 2008, Hemoglobin.

First Spanish Case Of Thalassemia Major Due to a Compound Heterozygosity for the IVS-II-848 (C→A) And Codon 39 (C→T) Mutations Of The β-Globin Gene

P. Ropero, O. Briceño, A. Villegas, 2006, Hemoglobin.

The identification of five rare beta-chain abnormal hemoglobins by high performance liquid chromatographic procedures.

A. Kutlar, T. Huisman, A. Villegas, 1986, Hemoglobin.

An Electronic Infrastructure for Research and Treatment of the Thalassemias and Other Hemoglobinopathies: The Euro-Mediterranean Ithanet Project

A. Zafeiropoulos, F. Grosveld, R. Gambari, 2009, Hemoglobin.

[Molecular characterization of two new mutations of α° thalassemia in two Spanish families (mutation --(ED) and --(GP))].

E. Anguita, P. Ropero, Aurora Hernández, 2011, Medicina clinica.

Haemoglobinopathies that occur with decreased HbA2 levels: a gene mutation set involving the δ gene at a Spanish centre

P. Ropero, A. Villegas, F. González, 2016, Journal of Clinical Pathology.

Delta0-thalassemia by insertion of 27 base pairs in δ-globin gene with decreased hemoglobin A2 levels

P. Ropero, A. Villegas, F. González, 2015 .

The First Case of Hb E-Saskatoon Associated with Hb Lepore-Baltimore Found in Spain

P. Ropero, A. Villegas, F. González, 2005, Hemoglobin.

Characterization of chromosomes with hybrid genes for Hb Lepore-Washington, Hb Lepore-Baltimore, Hb P-Nilotic, and Hb Kenya

G. Efremov, A. Villegas, P. Ojwang, 1987, Human Genetics.

A deletion of 11 bp (CD 131–134) in exon 3 of the β-globin gene produces the phenotype of inclusion body β-thalassemia

M. Mateo, P. Ropero, A. Villegas, 2005, Annals of Hematology.

Hb Santander [β34(B16)Val→Asp (GTC→GAC)]: A New Unstable Variant Found as a De Novo Mutation in a Spanish Patient

E. Rodrigo, M. Mateo, P. Ropero, 2003, Hemoglobin.

A NOVEL SPLICE ACCEPTOR SITE MUTATION OF THE α2-GLOBIN GENE CAUSING α-THALASSEMIA

N. Noguera, A. Villegas, F. González, 2001 .

Hb Nivaria: A New Hemoglobin Variant with a Shortened α-Globin Chain [α139(HC1)Lys→Stop; HBA1: c.418A>T]

A. Villegas, S. Rochas, F. González, 2022, Hemoglobin.

Autoimmune haemolytic anaemias: A retrospective study of 93 patients

Á. Cervera, B. Arrizabalaga, A. Villegas, 2020 .

Thrombosis and severe asthenia as priority manifestations in paroxysmal nocturnal haemoglobinuria

A. Villegas, F. González, E. Fontanes, 2012, Annals of Hematology.

Hb Palencia: a novel δβδ-type two-way fusion variant with β-globin-like expression levels

J. Alonso, P. Ropero, A. Villegas, 2018, Journal of Clinical Pathology.

Characterization of deletional and non-deletional alpha globin variants in a large cohort from Spain between 2009 and 2014

P. Ropero, A. Villegas, F. González, 2019, Annals of Hematology.

Hb Cervantes, Hb Marañón, Hb La Mancha and Hb Goya: Description of 4 new haemoglobinopathies.

Á. Cervera, J. Anguita, P. Ropero, 2015, Clinical biochemistry.

Heterozygosity for deletion of hypersensitive site 3 in the human locus control region has an unexpected minor effect on red cell phenotype

P. Ropero, A. Villegas, F. González, 2014, Journal of Human Genetics.

16189 Mitochondrial variant and iron overload

P. Ropero, A. Villegas, F. González, 2007, Annals of Hematology.

Emerging hematological targets and therapy for cardiovascular disease: From bench to bedside

S. Redondo, A. Villegas, F. González, 2008, Biologics : targets & therapy.

Another Hb with inclusion bodies β-thalassemia, owing to Hb Durham-N.C. [β114(G16) Leu > Pro]. First case described in Hispanic populations

M. Morado, R. Cordoba, P. Ropero, 2012, Annals of Hematology.

Red blood cell phenotypes in alpha-thalassemias in the Spanish population.

B. Arrizabalaga, A. Villegas, F. González, 1998, Haematologica.

A MUTATION IN THE POLYADENYLATION SIGNAL OF THE α2 GLOBIN GENE (AATAA→AATA–) AS A CAUSE OF α THALASSAEMIA IN ASIAN INDIANS

D. Higgs, G. Hall, P. Murphy, 1994, British journal of haematology.

α‐thalassemia‐1 (— −‐CAL mutation) in a Spanish family

P. Ropero, A. Villegas, F. González, 1994, American journal of hematology.

Molecular characterization of a new family with α‐Thalassemia‐1 (——MA mutation)

D. Espinós, P. Ropero, A. Villegas, 1995, American journal of hematology.

Congenital dyserythropoietic anemia type III with unbalanced globin chain synthesis

P. Ropero, V. Furió, A. Villegas, 1994, European journal of haematology.

Autosomal Recessive Congenital Dyserythropoietic Anemia Type III Is Caused By Mutations in the Centralspindlin RACGAP1 Component

C. Tornador, Mayka Sánchez, M. Morado, 2021, Blood.

Erythrocytosis in a Child due to Hb Andrew-Minneapolis [β144(HC1)Lys→Asn (AAG>AAT or AAC)] Associated with a Spanish (δβ)0-Thalassemia

C. Serí, C. Beléndez, P. Ropero, 2013, Hemoglobin.

Chronic haemolytic anaemia because of pyruvate kinase (PK) deficiency in a child heterozygous for haemoglobin S and no clinical features of sickle cell disease

L. Manco, C. Bento, J. Vagace, 2010, European journal of haematology.

Homozygous Constant Spring: the first case described in the west.

E. Anguita, N. Noguera, P. Ropero, 2000, Haematologica.

Hereditary xerocytosis, a misleading anemia

C. Bento, J. C. García-Ruiz, B. Arrizabalaga, 2016, Annals of Hematology.

Hb Extremadura [β64(E8)Gly→Ser;β133(H11)Val→Leu]: A New Molecular Analysis

P. Ropero, A. Villegas, F. González, 2011, Hemoglobin.

Hb AGENOGI [β90(F6)Glu→Lys] IN AN ARGENTINEAN GIRL

N. Noguera, A. Villegas, F. González, 2002, Hemoglobin.

[Association between hemoglobin Groene Hart and hemoglobin J-Paris-I: first case in Spain].

P. Ropero, A. Villegas, F. González, 2015, Medicina clinica.

Hb Cibeles [α2 CD25(B6) (Gly → Asp)]: a novel alpha chain variant causing alpha-thalassemia

J. Sevilla, P. Ropero, A. Villegas, 2014, International journal of hematology.

HB Extremadura or α2β2133(H11)VAU→LEU, A New Mildly Unstable Hemoglobin in a Spanish Female

A. Kutlar, T. Huisman, A. Villegas, 1989 .

Characterization of a new hemoglobin variant: Hb Badalona (β31[B13]Leu→Val)

P. Ropero, A. Villegas, F. González, 2002, Annals of Hematology.

HB Puerta del Sol [HBA1:c.148A>C], HB Valdecilla [HBA2:c.3G>T], HB Gran Vía [HBA2:c.98T>G], HB Macarena [HBA2:c.358C>T] and HB El Retiro [HBA2:c.364_366dupGTG]: description of five new hemoglobinopathies

A. Escudero, A. Fernández-Teijeiro, P. Ropero, 2016, Clinical chemistry and laboratory medicine.

Study of Three Families with Hb Agrinio [α29(B10)Leu→Pro, CTG>CCG (α2)] in the Spanish Population: Three Homozygous Cases

M. Baiget, I. Badell, P. Ropero, 2012, Hemoglobin.

[Prenatal diagnosis of hemoglobinopathies and thalassemias].

P. Ropero, Aurora Hernández, A. Villegas, 2009, Medicina clinica.

Identification of a Novel Mutation in the β-Globin Gene 3′ Untranslated Region (HBB: c.*+118A > G) in Spain

P. Ropero, A. Villegas, F. González, 2015, Hemoglobin.

Darbepoetin alfa for anemia in patients with low or intermediate-1 risk myelodysplastic syndromes and positive predictive factors of response

J. González-Porras, Á. Remacha, E. Luño, 2011, Current medical research and opinion.

Hb Murcia (β118(G19)His>Gln): A New Hemoglobin Variant Found in a Spanish Woman

P. Ropero, A. Villegas, F. G. Fernández, 2021, Annals of laboratory medicine.

Molecular heterogeneity of β‐thalassaemia in a Spanish population from the area centre of Spain

P. Ropero, A. Villegas, F. González, 1996, European Journal of Haematology.

High incidence of the CD8/9 (+G) beta 0-thalassemia mutation in Spain.

E. Anguita, P. Ropero, A. Villegas, 1998, Haematologica.

Hb Johnstown [β109 (G11) Val→Leu]: Second case described and associated for the first time with β0‐thalassemia in two Spanish families

E. Anguita, B. Arrizabalaga, P. Ropero, 2000 .

High incidence of the CD8/9 (+G) b0-thalassemia mutation in Spain

E. Anguita, P. Ropero, A. Villegas, 2005 .

Nondeletional α-Thalassemia: Two New Mutations on the α2 Gene

P. Ropero, A. Villegas, F. González, 2020, Hemoglobin.

Frameshift CD 11 (-T) beta-thalassemia mutation.

A. Villegas, F. González, J. Sanchez, 1997, American journal of hematology.

Acute promyelocytic leukemia relapse in the central nervous system during hematologic and molecular remission

F. Lo Coco, E. Anguita, A. Villegas, 1999, American journal of hematology.

A Novel Mutation of the α2-Globin causing α+-Thalassemia: Hb Plasencia [α125(H8)Leu→Arg (α2)

M. Mateo, P. Ropero, A. Villegas, 2005 .