D. Iusuf

发表

OATP1A/1B Transporters Affect Irinotecan and SN-38 Pharmacokinetics and Carboxylesterase Expression in Knockout and Humanized Transgenic Mice

E. van de Steeg, O. van Tellingen, M. Ludwig, 2013, Molecular Cancer Therapeutics.

Angiotensin-(1-7): pharmacological properties and pharmacotherapeutic perspectives.

R. Henning, W. V. van Gilst, A. Roks, 2008, European journal of pharmacology.

Murine Oatp1a/1b Uptake Transporters Control Rosuvastatin Systemic Exposure Without Affecting Its Apparent Liver Exposure

E. van de Steeg, A. Schinkel, E. Wagenaar, 2013, Molecular Pharmacology.

P-Glycoprotein (ABCB1) Transports the Primary Active Tamoxifen Metabolites Endoxifen and 4-Hydroxytamoxifen and Restricts Their Brain Penetration

H. Rosing, J. Beijnen, A. Schinkel, 2011, Journal of Pharmacology and Experimental Therapeutics.

Abcc4 Together with Abcb1 and Abcg2 Form a Robust Cooperative Drug Efflux System That Restricts the Brain Entry of Camptothecin Analogues

J. Schellens, J. Beijnen, D. Pluim, 2013, Clinical Cancer Research.

Human OATP1B1, OATP1B3 and OATP1A2 can mediate the in vivo uptake and clearance of docetaxel

H. Rosing, J. Beijnen, E. van de Steeg, 2015, International journal of cancer.

Cancer Therapy : Preclinical Abcc 4 Together with Abcb 1 and Abcg 2 Form a Robust Cooperative Drug Ef fl ux System That Restricts the Brain Entry of Camptothecin Analogues

J. Schellens, J. Beijnen, D. Pluim, 2013 .

P-Glycoprotein, Multidrug-Resistance Associated Protein 2, Cyp3a, and Carboxylesterase Affect the Oral Availability and Metabolism of Vinorelbine

C. Damen, J. Beijnen, A. Schinkel, 2012, Molecular Pharmacology.

Liquid chromatography-tandem mass spectrometric assay for the light sensitive tyrosine kinase inhibitor axitinib in human plasma.

J. Schellens, J. Beijnen, A. Schinkel, 2009, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Bradykinin Protects Against Oxidative Stress–Induced Endothelial Cell Senescence

R. Henning, P. van der Harst, W. V. van Gilst, 2009, Hypertension.

Bradykinin protects against endothelial cell senescence

P. Harst, R. Henning, W. H. Gilst, 2008 .

Organic anion-transporting polypeptides 1a/1b control the hepatic uptake of pravastatin in mice.

J. Beijnen, E. van de Steeg, A. Schinkel, 2012, Molecular pharmaceutics.

Differential Impact of P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) on Axitinib Brain Accumulation and Oral Plasma Pharmacokinetics

Jos H Beijnen, J. Beijnen, A. Schinkel, 2011, Drug Metabolism and Disposition.

Functions of OATP1A and 1B transporters in vivo: insights from mouse models.

E. van de Steeg, A. Schinkel, D. Iusuf, 2012, Trends in pharmacological sciences.

Abcc 4 together with Abcb 1 and Abcg 2 form a robust co-operative drug efflux system that restricts the brain entry of camptothecin analogs

J. Beijnen, D. Pluim, R. Mazzanti, 2013 .

Hepatocyte Hopping of OATP1B Substrates Contributes to Efficient Hepatic Detoxification

A. Schinkel, E. Steeg, D. Iusuf, 2012, Clinical pharmacology and therapeutics.

Liquid chromatography-tandem mass spectrometric assay for pravastatin and two isomeric metabolites in mouse plasma and tissue homogenates.

J. Schellens, J. Beijnen, A. Schinkel, 2010, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Functions of OATP1A and 1B transporters in vivo: insights from mouse models.

E. van de Steeg, A. Schinkel, D. Iusuf, 2012, TIPS - Trends in Pharmacological Sciences.