Haeil Park

发表

The neuroprotective effect of eupatilin against ischemia/reperfusion-induced delayed neuronal damage in mice.

Dong Hyun Kim, Se Jin Park, J. Choi, 2012, European journal of pharmacology.

Biochemical pharmacology of biflavonoids: Implications for anti-inflammatory action

Hyun Pyo Kim, H. Chang, S. Kang, 2008, Archives of pharmacal research.

Synthesis and inhibitory activity against COX-2 catalyzed prostaglandin production of chrysin derivatives.

Hyun Pyo Kim, Sanghee Kim, Jeongsoon Kim, 2004, Bioorganic & medicinal chemistry letters.

Synthesis and Cell Death Mechanism of a Militarin Derivative: Synthesis and Biology of a Militarin Derivative

Fei Chen, G. Sung, J. Cho, 2016 .

Synthesis of (±)-methyl-(1 -aryl-4-pyridin-3-yl-but-3-enyl)-amines

Jinhee Jang, Haeil Park, K. Sin, 2001, Archives of pharmacal research.

A concise synthetic pathway fortrans-metanicotine analogues

Jinhee Jang, Haeil Park, K. Sin, 2000, Archives of pharmacal research.

A novel synthetic analog of Militarin, MA-1 induces mitochondrial dependent apoptosis by ROS generation in human lung cancer cells.

B. Jeon, G. Sung, J. Cho, 2013, Toxicology and applied pharmacology.

Synthetic wogonin derivatives suppress lipopolysaccharide-induced nitric oxide production and hydrogen peroxide-induced cytotoxicity

Sung-soo Kim, Gun-Hee Lee, W. Chun, 2005, Archives of pharmacal research.

New synthetic anti-inflammatory chrysin analog, 5,7-dihydroxy-8-(pyridine-4yl)flavone.

H. Lim, Hyun Pyo Kim, Haeil Park, 2011, European journal of pharmacology.

Inhibition of prostaglandin production by a structurally-optimized flavonoid derivative, 2',4',7-trimethoxyflavone and cellular action mechanism.

Hyun Pyo Kim, H. Chang, Chang-Kyun Han, 2005, Biological & pharmaceutical bulletin.

Inhibition of nitric oxide production from lipopolysaccharide-treated RAW 264.7 cells by synthetic flavones: Structure-activity relationship and action mechanism

Hyun Pyo Kim, S. Kim, Haeil Park, 2004, Archives of pharmacal research.

Inhibition of contact dermatitis in animal models and suppression of proinflammatory gene expression by topically applied Flavonoid, Wogonin

H. Lim, Hyun Pyo Kim, Haeil Park, 2004, Archives of pharmacal research.

Effects of wogonin, a plant flavone from Scutellaria radix, on skin inflammation: in vivo regulation of inflammation-associated gene expression.

H. Lim, Hyun Pyo Kim, Haeil Park, 2003, Biochemical pharmacology.

Flavonoids interfere with NLRP3 inflammasome activation

H. Lim, Hyun Pyo Kim, Haeil Park, 2018, Toxicology and applied pharmacology.

New anti-inflammatory synthetic biflavonoid with C-C (6-6″) linkage: Differential effects on cyclooxygenase-2 and inducible nitric oxide synthase

H. Lim, Hyun Pyo Kim, H. Chang, 2009, Archives of pharmacal research.

Anti-inflammatory activity of the synthetic chalcone derivatives: inhibition of inducible nitric oxide synthase-catalyzed nitric oxide production from lipopolysaccharide-treated RAW 264.7 cells.

Hyun Pyo Kim, Jeongsoon Kim, Haeil Park, 2007, Biological & pharmaceutical bulletin.

Anti‐inflammatory activity of the synthetic C‐C biflavonoids

Hyun Pyo Kim, H. Chang, Haeil Park, 2006, The Journal of pharmacy and pharmacology.

3-(4-(tert-Octyl)phenoxy)propane-1,2-diol suppresses inflammatory responses via inhibition of multiple kinases.

M. Rhee, G. Sung, J. Cho, 2012, Biochemical pharmacology.

Paclitaxel and docetaxel photoaffinity labels

R. Himes, G. Georg, Haeil Park, 1995 .

A chrysin analog exhibited strong inhibitory activities against both PGE2 and NO production.

H. Lim, Hyun Pyo Kim, Haeil Park, 2011, European journal of medicinal chemistry.

Synthesis and inhibition of PGE2 production of 6,8-disubstituted chrysin derivatives.

Hyun Pyo Kim, Haeil Park, Tran Thanh Dao, 2005, European journal of medicinal chemistry.

Remote Stereoinductive Intramolecular Nitrile Oxide Cycloaddition: Asymmetric Total Synthesis and Structure Revision of (-)-11β-Hydroxycurvularin.

Joo Yun Lee, Y. Kang, J. Y. Lee, 2016, The Journal of organic chemistry.

Synthesis of biflavones having a 6-O-7'' linkage and effects on cyclooxygenase-2 and inducible nitric oxide synthase.

H. Lim, Hyun Pyo Kim, H. Chang, 2009, Bioorganic & medicinal chemistry letters.

Synthesis of biologically active 2-benzoyl paclitaxel analogues

R. Himes, G. Georg, A. Datta, 1995 .

SYNTHESIS AND BIOLOGY OF SUBSTITUTED 3'-PHENYL TAXOL ANALOGUES

R. Himes, M. Hepperle, G. Georg, 1994 .

Topliss approach to the synthesis of biologically active substituted N-benzoyl taxol analogues

R. Himes, M. Hepperle, G. Georg, 1994 .

Practical Synthesis of (±)-Nyasol

Yuanying Fang, Haeil Park, 2015 .

Cross-Metathesis of Methallyl Halides: Concise Enantioselective Formal Total Synthesis of (–)-Presphaerene

H. Nallapaneni, Jongkook Lee, Haeil Park, 2020, Frontiers in Chemistry.

Highly Stereoselective Asymmetric Total Synthesis of (-)-Jimenezin via Sequential Intramolecular Amide Enolate Alkylation.

Hyoungsu Kim, Deukjoon Kim, Thuy Trang Pham, 2022, Organic letters.

Stereoselective Protection-Free Asymmetric Total Synthesis of (+)-Chamuvarinin, a Potent Anticancer and Antitrypanosomal Agent: Substrate-Controlled Construction of the Adjacently Linked Oxatricyclic Core by Internal Alkylation.

Deukjoon Kim, Jongkook Lee, Haeil Park, 2018, Organic letters.

Stereoselective construction of 2,6-cis-disubstituted tetrahydropyrans via intramolecular amide enolate alkylation: total synthesis of (-)-centrolobine.

Chi-Hoon Park, Hyoungsu Kim, M. Latif, 2015, The Journal of organic chemistry.

Synthesis and inhibition of PGE2 production of 6,8-disubstituted chrysin derivatives.

Hyun Pyo Kim, Haeil Park, Tran Thanh Dao, 2005, European journal of medicinal chemistry.

Structure and antiinflammatory activity relationships of wogonin derivatives

Hyun Pyo Kim, Jinhee Jang, Haeil Park, 2005, Archives of pharmacal research.

Synthesis and PGE2 inhibitory activity of vinylated and allylated chrysin analogues

Hyun Pyo Kim, Haeil Park, Tran Thanh Dao, 2003, Archives of pharmacal research.

Taxol®: science and applications.

Michael L. Shuler, Haeil Park, William C. Rose, 1995 .

1,5-Diarylimidazoles with strong inhibitory activity against COX-2 catalyzed PGE2 production from LPS-induced RAW 264.7 cells.

Hyun Pyo Kim, Haeil Park, Haiyan Che, 2010, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of pyrimidine derivatives with diverse azabicyclic ether/amine as novel GPR119 agonist.

Yuanying Fang, Zunhua Yang, Haeil Park, 2017, Bioorganic & medicinal chemistry letters.

Novel 5-nitropyrimidine derivatives bearing endo-azabicyclic alcohols/amines as potent GPR119 agonists.

Yuanying Fang, Zunhua Yang, Jongkook Lee, 2017, Bioorganic & Medicinal Chemistry.

Synthesis and biological evaluation of novel 2,4-disubstituted quinazoline analogues as GPR119 agonists.

Tuan-Anh N. Pham, Yuanying Fang, Zunhua Yang, 2013, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of 5-nitropyrimidine analogs with azabicyclic substituents as GPR119 agonists.

Tuan-Anh N. Pham, Yuanying Fang, Zunhua Yang, 2013, Bioorganic & medicinal chemistry letters.

The ameliorating effects of 5,7-dihydroxy-6-methoxy-2(4-phenoxyphenyl)-4H-chromene-4-one, an oroxylin A derivative, against memory impairment and sensorimotor gating deficit in mice

Dong Hyun Kim, M. Geyer, J. Cheong, 2013, Archives of Pharmacal Research.

Synthesis, in vitro evaluation, and computational simulations studies of 1,2,3-triazole analogues as DPP-4 inhibitors.

K. H. Hong, Jongkook Lee, Haeil Park, 2020, Bioorganic & medicinal chemistry.

Zinc-Mediated Allylation of N-Protected α-Amino Aldehydes in Aqueous Solution. Stereoselective Synthesis of Phe-Phe Hydroxyethylene Dipeptide Isosteres

S. Hanessian, Haeil Park, Rui Yang, 1997 .

Zinc-Mediated Allylation of N-Protected α-Amino Aldehydes in Aqueous Solution. Stereoselective Synthesis of Anti- and Syn-β-Amino Alcohols with Functionalized Allyl Groups

S. Hanessian, Haeil Park, Rui Yang, 1997 .

The ameliorating effects of 5,7-dihydroxy-6-methoxy-2(4-phenoxyphenyl)-4H-chromene-4-one, an oroxylin A derivative, against memory impairment and sensorimotor gating deficit in mice

Dong Hyun Kim, Se Jin Park, M. Geyer, 2013, Archives of pharmacal research.

Synthesis and Structure Revision of Dimeric Tadalafil Analogue Adulterants in Dietary Supplements.

J. H. Lee, Jongkook Lee, S. Baek, 2017, Chemical & pharmaceutical bulletin.

An efficient semisynthesis of taxol from (3R,4S)-N-Benzoyl-3-[(t-butyldimethylsilyl)oxy]-4-phenyl-2-azetidinone and 7-(Triethylsilyl)baccatin III

M. Hepperle, G. Georg, G. Harriman, 1993 .

Phosphine-catalyzed allylic substitution of Morita-Baylis-Hillman acetates: synthesis of N-protected beta-aminophosphonic acid esters.

M. Krische, Haeil Park, C. Cho, 2006, The Journal of organic chemistry.

Effects of flavonoids on senescence-associated secretory phenotype formation from bleomycin-induced senescence in BJ fibroblasts.

H. Lim, Hyun Pyo Kim, Haeil Park, 2015, Biochemical pharmacology.

Effects of flavonoids on matrix metalloproteinase-13 expression of interleukin-1β-treated articular chondrocytes and their cellular mechanisms: inhibition of c-Fos/AP-1 and JAK/STAT signaling pathways.

H. Lim, Hyun Pyo Kim, Haeil Park, 2011, Journal of pharmacological sciences.

Synthesis andin vitro antibacterial activity of cephalosporins with a pyridinium substituent carrying an isoxazole moiety at the C-3 position

Jinhee Jang, Minsun Chang, Haeil Park, 2001, Archives of pharmacal research.

Novel 1,2,3‐Triazole Analogs of Sitagliptin as DPP4 Inhibitors

Jongkook Lee, Haeil Park, Shankariah Gundeti, 2016 .

Synthesis of New 4-(tert-Octyl)phenol Derivatives and Their Anticancer Activity against Human Prostate and Lung Cancer Cell Lines

S. K. Gurung, G. Sung, Yuanying Fang, 2014 .

Synthesis of phospholipase A2 inhibitory biflavonoids.

Hyun Pyo Kim, H. Chang, Jianjun Chen, 2006, Bioorganic & medicinal chemistry letters.

Taxol photoaffinity labels 2. Synthesis and biological evaluation of N-(4-azidobenzoyl)-N-debenzoyltaxol, N-(4-azido-2,3,5,6-tetrafluorobenzoyl)-N-debenzoyltaxol, and 7-(4-azido-2,3,5,6-tetrafluorobenzoyl)taxol

R. Himes, G. Georg, G. Harriman, 1994 .

Prenylated flavonoids as tyrosinase inhibitors

Hyun Pyo Kim, H. Chang, S. Kang, 2004, Archives of pharmacal research.

5,7-Dihydroxy-6-methoxy-4'-phenoxyflavone, a derivative of oroxylin A improves attention-deficit/hyperactivity disorder (ADHD)-like behaviors in spontaneously hypertensive rats.

Yeni Kim, Chan Young Shin, Haeil Park, 2013, European journal of pharmacology.

Oroxylin A improves attention deficit hyperactivity disorder-like behaviors in the spontaneously hypertensive rat and inhibits reuptake of dopamine in vitro

J. Cheong, C. Shin, K. Son, 2013, Archives of pharmacal research.

Synthesis of Halogenated 1,5-Diarylimidazoles and Their Inhibitory Effects on LPS-Induced PGE2 Production in RAW 264.7 Cells

Kyung-Tae Lee, Yuanying Fang, Zunhua Yang, 2021, Molecules.

Synthesis of 1,5-diarylhaloimidazole analogs and their inhibitory activities against PGE₂ production from LPS-treated RAW 264.7 cells.

Tuan-Anh N. Pham, Sung-soo Kim, Zunhua Yang, 2012, Bioorganic & medicinal chemistry.

Small molecule inhibitors of the hedgehog signaling pathway for the treatment of cancer

S. K. Kim, H. Kim, Jongkook Lee, 2012, Archives of Pharmacal Research.

Small molecule inhibitors of the hedgehog signaling pathway for the treatment of cancer

H. Kim, Jongkook Lee, Haeil Park, 2012, Archives of Pharmacal Research.

5,6,7-trimethoxyflavone suppresses pro-inflammatory mediators in lipopolysaccharide-induced RAW 264.7 macrophages and protects mice from lethal endotoxin shock.

Kyung-Tae Lee, Ji-Sun Shin, D. Jang, 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Schotten-Baumann acylation of N-debenzoyltaxol; an efficient route to N-acyl taxol analogues and their biological evaluation

R. Himes, M. Hepperle, G. Georg, 1994 .

Inhibitory effect of synthetic C-C biflavones on various phospholipase A(2)s activity.

T. Moon, Hyun Pyo Kim, H. Chang, 2007, Bioorganic & medicinal chemistry.

Synthesis and Anti-inflammatory Activity of Phenylbutenoid Dimer Analogs

Sung-soo Kim, Yuanying Fang, Haeil Park, 2015 .

Straightforward and Facile Synthesis of a Bioactive Component from Zingiber cassumunar Roxb.

Yuanying Fang, Zunhua Yang, Haeil Park, 2014 .

Inhibitory Activity of Cordyceps bassiana Extract on LPS-induced Inflammation in RAW 264.7 Cells by Suppressing NF-κB Activation

G. Sung, Yuanying Fang, K. Hwang, 2017 .

Total Synthesis of Amentoflavone

Jianjun Chen, Haeil Park, Chuan-Ling Si, 2015 .

First Syntheses of (±)‐Butesuperins A and B

Jongkook Lee, Haeil Park, B. Ganganna, 2017 .

Synthesis and biological activities of 8-arylflavones

Sanghee Kim, Haeil Park, Tran Thanh Dao, 2004, Archives of pharmacal research.

Synthesis and PGE2 Inhibitory Activity of 5,7-Dihydroxyflavones and TheirO-Methylated Flavone Analogs

Hyun Pyo Kim, Sanghee Kim, Jeongsoon Kim, 2003, Archives of pharmacal research.

Structural Alterations of Wogonin Significantly Reduce the Inhibitory Activity against COX-2 Catalyzed PGE 2 Production from LPS-Induced RAW 264.7 Cells

H. Lim, Hyun Pyo Kim, Haeil Park, 2009 .

1,2, 3‐Triazole analogs with bulky and conformationally rigid substructures: Synthesis and in vitro evaluation as DPP ‐4 inhibitors

Jongkook Lee, Haeil Park, Duy-Viet Vo, 2023, Bulletin of the Korean Chemical Society.

Inhibitory activity of prostaglandin E2 production by the synthetic 2'-hydroxychalcone analogues: Synthesis and SAR study.

G. Ecker, Hyun Pyo Kim, K. Thai, 2009, Bioorganic & Medicinal Chemistry Letters.

Oroxylin A analogs exhibited strong inhibitory activities against iNOS-mediated nitric oxide (NO) production.

Tuan-Anh N. Pham, Sung-soo Kim, Jae-Won Lee, 2012, Bioorganic & medicinal chemistry letters.

New anti-inflammatory synthetic biflavonoid with C-C (6-6″) linkage: Differential effects on cyclooxygenase-2 and inducible nitric oxide synthase

H. Lim, Hyun Pyo Kim, H. Chang, 2009, Archives of pharmacal research.

Inhibition of prostaglandin E2 production by synthetic Wogonin analogs

Hyun Pyo Kim, Haeil Park, S. Gurung, 2009, Archives of pharmacal research.

Synthesis of biflavones having a 6-O-7'' linkage and effects on cyclooxygenase-2 and inducible nitric oxide synthase.

H. Lim, Hyun Pyo Kim, H. Chang, 2009, Bioorganic & medicinal chemistry letters.

Synthesis and antiinflammatory activity of 1,5-Diarylimidazoles

Hyun Pyo Kim, Haeil Park, K. Sin, 2005, Archives of pharmacal research.