Shiwen Xu

Yujie Yao, Zhiying Miao, Shiwen Xu, 2022, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Failed Degradation of JunB Contributes to Overproduction of Type I Collagen and Development of Dermal Fibrosis in Patients With Systemic Sclerosis

D. Abraham, C. Denton, A. Holmes, 2014, Arthritis & rheumatology.

Cineole alleviates the BPA-inhibited NETs formation by regulating the p38 pathway-mediated programmed cell death.

Zhihui Jiang, Shiwen Xu, Tian Wang, 2022, Ecotoxicology and environmental safety.

TMT induces apoptosis and necroptosis in mouse kidneys through oxidative stress-induced activation of the NLRP3 inflammasome.

Meng-yao Guo, Shiwen Xu, Xiao-jing Liu, 2022, Ecotoxicology and environmental safety.

Polystyrene nanoplastics induced cardiomyocyte apoptosis and myocardial inflammation in carp by promoting ROS production.

Yujie Yao, Jinming Guo, Shiwen Xu, 2022, Fish & shellfish immunology.

Microplastics and di (2-ethylhexyl) phthalate synergistically induce apoptosis in mouse pancreas through the GRP78/CHOP/Bcl-2 pathway activated by oxidative stress.

Xinyue Sun, Shiwen Xu, Yuqi Wang, 2022, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Combined exposure to di(2-ethylhexyl) phthalate and polystyrene microplastics induced renal autophagy through the ROS/AMPK/ULK1 pathway.

Wenyue Zhang, Xinyue Sun, Shiwen Xu, 2022, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Melatonin attenuates bisphenol A-induced colon injury by dual targeting mitochondrial dynamics and Nrf2 antioxidant system via activation of SIRT1/PGC-1α signaling pathway.

Yujie Yao, N. Yang, Shiwen Xu, 2022, Free radical biology & medicine.

BPA exposure aggravates necroptosis of myocardial tissue in selenium deficient broilers through NO-dependent endoplasmic reticulum stress.

Jing Liu, Shengchen Wang, Shiwen Xu, 2022, Toxicology.

Melatonin ameliorates imidacloprid-induced intestinal injury by negatively regulating the PGN/P38MAPK pathway in the common carp (Cyprinuscarpio).

Zhiying Miao, Zhiruo Miao, Shiwen Xu, 2022, Fish & shellfish immunology.

Di-(2-ethyl hexyl) phthalate induced oxidative stress promotes microplastics mediated apoptosis and necroptosis in mice skeletal muscle by inhibiting PI3K/AKT/mTOR pathway.

Wenyue Zhang, Xinyue Sun, Shiwen Xu, 2022, Toxicology.

ROS-mediated PPAR/RXR inhibition contributes to acetochlor-induced apoptosis and autophagy in Ctenopharyngodon idella hepatic cells.

Xiaojing Li, Shiwen Xu, Xu Shi, 2022, Fish & shellfish immunology.

Chlorpyrifos induces the apoptosis and necroptosis of L8824 cells through the ROS/PTEN/PI3K/AKT axis.

Shiwen Xu, Xu Shi, Lanqiao Wang, 2020, Journal of hazardous materials.

Aberrant expression of WDR4 affects the clinical significance of cancer immunity in pan-cancer

Shiwen Xu, Hanqiang Zeng, Yanyan Shen, 2021, Aging.

Connective tissue growth factor causes EMT-like cell fate changes in vivo and in vitro

D. Abraham, J. Norman, S. Sonnylal, 2013, Journal of Cell Science.

STAT3 controls COL1A2 enhancer activation cooperatively with JunB, regulates type I collagen synthesis posttranscriptionally, and is essential for lung myofibroblast differentiation

D. Abraham, C. Denton, M. Ponticos, 2018, Molecular biology of the cell.

Full-Length Transcriptome Profiling of Coridius chinensis Mitochondrial Genome Reveals the Transcription of Genes with Ancestral Arrangement in Insects

Y. Duan, Hu Li, Fan Song, 2023, Genes.

Protective effects of selenium against zearalenone-induced apoptosis in chicken spleen lymphocyte via an endoplasmic reticulum stress signaling pathway

Shiwen Xu, Zhan-jun Lu, Zhenzhong Hou, 2018, Cell Stress and Chaperones.

IL-6 promotes nuclear translocation of HIF-1α to aggravate chemoresistance of ovarian cancer cells.

Weimin Deng, Chunyan Yu, S. Huang, 2020, European journal of pharmacology.

Hyperglycaemia and Ischaemia Impair Wound Healing via Toll-like Receptor 4 Pathway Activation in vitro and in an Experimental Murine Model.

D. Baker, D. Abraham, J. Tsui, 2019, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

Over-expression of HER 2 promotes cell metastasis and is associated with the prognosis of osteosarcoma

Xin Zhang, Xiangyang Wu, Jian Wang, 2016 .

The Complete Mitochondrial Genome of the Chicken Body Louse, Menacanthus cornutus, and Evolutionary Patterns of Extensive Gene Rearrangements in the Mitochondrial Genomes of Amblycera (Psocodea: Phthiraptera)

Hu Li, Fan Song, W. Cai, 2022, Genes.

Di(2‐ethylhexyl) phthalate and microplastics cause necroptosis and apoptosis in hepatocytes of mice by inducing oxidative stress

Shiwen Xu, Chunyan Xu, Fuchang Yu, 2023, Environmental toxicology.

Polystyrene-microplastics and DEHP co-exposure induced DNA damage, cell cycle arrest and necroptosis of ovarian granulosa cells in mice by promoting ROS production.

N. Yang, Shiwen Xu, Hao Wu, 2023, The Science of the total environment.

Melatonin alleviates lead-induced intestinal epithelial cell pyroptosis in the common carps (Cyprinus carpio) via miR-17-5p/TXNIP axis.

X. Teng, Zhiying Miao, Zhiruo Miao, 2022, Fish & shellfish immunology.

The endoplasmic reticulum-mitochondrial crosstalk is involved in the mitigation mechanism of eucalyptol on imidacloprid toxicity in Ctenopharyngodon idellus kidney cells.

Xiaojing Li, Shiwen Xu, Xu Shi, 2022, Fish & shellfish immunology.

Oxidative stress mediated by the TLR4/NOX2 signalling axis is involved in polystyrene microplastic-induced uterine fibrosis in mice.

Tong Xu, Shiwen Xu, Hao Wu, 2022, The Science of the total environment.

Polystyrene microplastics-induced macrophage extracellular traps contributes to liver fibrotic injury by activating ROS/TGF-β/Smad2/3 signaling axis.

Shiwen Xu, Yue Wang, Xu Shi, 2023, Environmental pollution.

ROS mediated pyroptosis-M1 polarization crosstalk participates in inflammation of chicken liver induced by bisphenol a and selenium deficiency.

Wenyue Zhang, Xiaojing Li, Xinyue Sun, 2023, Environmental pollution.

Clinical and pathological significance of interleukin 6 overexpression in systemic sclerosis

D. Abraham, C. Denton, S. Nihtyanova, 2012, Annals of the rheumatic diseases.

Eucalyptol antagonized the apoptosis and immune dysfunction of grass carp hepatocytes induced by tetrabromobisphenol A by regulating ROS/ASK1/JNK pathway

Huijun Zhu, Shiwen Xu, Wenying Sun, 2023, Environmental toxicology.

TBBPA induces inflammation, apoptosis, and necrosis of skeletal muscle in mice through the ROS/Nrf2/TNF-α signaling pathway.

Meng-yao Guo, Shengchen Wang, Shiwen Xu, 2022, Environmental pollution.

Cadmium exposure causes mitochondrial fission and fusion disorder in the pig hypothalamus via the PI3K/AKT pathway.

Yujie Yao, Shiwen Xu, Xiaohang Li, 2022, Ecotoxicology and environmental safety.

Melatonin alleviates lead-induced fatty liver in the common carps (Cyprinus carpio) via gut-liver axis.

X. Teng, Zhiying Miao, Zhiruo Miao, 2022, Environmental pollution.

Trimethyltin induces apoptosis and necroptosis of mouse liver by oxidative stress through YAP phosphorylation.

Hongyuan Jing, Meng-yao Guo, Shiwen Xu, 2022, Ecotoxicology and environmental safety.

New Insights into Baicalein's Effect on Chlorpyrifos-Induced Liver Injury in Carp: Involving Macrophage Polarization and Pyropto sis.

Wenyue Zhang, Jing Liu, Shiwen Xu, 2023, Journal of agricultural and food chemistry.

Polystyrene microplastics induced inflammation with activating the TLR2 signal by excessive accumulation of ROS in hepatopancreas of carp (Cyprinus carpio).

Yanhe Zhang, Shiwen Xu, Lin Liu, 2023, Ecotoxicology and environmental safety.

H2S Exposure Induces Autophagy Injury in The Jejunum of Broilers Through miR-181a-PKC-δ Axis Mediated ER Stress

Shufang Zheng, Jinming Guo, Wenjing Zhu, 2021 .

The Antagonistic Effects of Selenium Yeast (SeY) on Cadmium-Induced Inflammatory Factors and the Heat Shock Protein Expression Levels in Chicken Livers

Shiwen Xu, Dayong Tao, Yong Wang, 2020, Biological Trace Element Research.

Selenium Deficiency Induces Inflammation via the iNOS/NF-κB Pathway in the Brain of Pigs

Shiwen Xu, Yilei Zhang, J. Cui, 2019, Biological Trace Element Research.

New Insights into How Melatonin Ameliorates Bisphenol A-Induced Colon Damage: Inhibition of NADPH Oxidase.

Yujie Yao, Wenjing Zhu, Shiwen Xu, 2023, Journal of agricultural and food chemistry.

Selective deletion of connective tissue growth factor attenuates experimentally-induced pulmonary fibrosis and pulmonary arterial hypertension

D. Abraham, C. Denton, A. Holmes, 2021, The international journal of biochemistry & cell biology.

Analysis of a functional polymorphism in the CTGF/CCN2 promoter in Systemic Sclerosis.

D. Abraham, C. Denton, A. Holmes, 2005 .

Tripterygium wilfordii derivative celastrol, a YAP inhibitor, has antifibrotic effects in systemic sclerosis

John Nguyen, J. Biernaskie, A. Leask, 2023, Annals of the Rheumatic Diseases.

Clinical and pathogenic significance of S100A4 overexpression in systemic sclerosis

Feng Zhang, C. Denton, J. Klingelhöfer, 2023, Annals of the Rheumatic Diseases.

Single-cell analysis reveals key differences between early-stage and late-stage systemic sclerosis skin across autoantibody subgroups

C. Denton, V. Ong, Shiwen Xu, 2023, Annals of the Rheumatic Diseases.

Exposure to polystyrene microplastics triggers lung injury via targeting toll-like receptor 2 and activation of the NF-κB signal in mice.

Meng-yao Guo, Shiwen Xu, Ran Xu, 2023, Environmental pollution.

Autocrine overexpression of CTGF maintains fibrosis: RDA analysis of fibrosis genes in systemic sclerosis.

D. Pennington, R. D. du Bois, D. Abraham, 2000, Experimental cell research.

Full-length transcriptome profiling of Aphidius gifuensis mitochondrial genome with gene rearrangement and control region duplication

Hu Li, Fan Song, W. Cai, 2023, Heliyon.

A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis

B. Suki, R. Lafyatis, D. Abraham, 2015, PloS one.

An essential role for resident fibroblasts in experimental lung fibrosis is defined by lineage-specific deletion of high-affinity type II transforming growth factor β receptor.

A. Wells, D. Abraham, C. Denton, 2011, American journal of respiratory and critical care medicine.

Selenium Prevents Lead-Induced Necroptosis by Restoring Antioxidant Functions and Blocking MAPK/NF-κB Pathway in Chicken Lymphocytes

Jiayong Zhang, Xiaofang Hao, Shiwen Xu, 2020, Biological Trace Element Research.

ROS/ER stress contributes to trimethyltin chloride-mediated hepatotoxicity; Tea polyphenols alleviate apoptosis and immunosuppression.

Huijun Zhu, Xiaojing Li, Shiwen Xu, 2022, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

CTGF and SMADs, Maintenance of Scleroderma Phenotype Is Independent of SMAD Signaling*

S. Sa, A. Leask, C. Black, 2001, The Journal of Biological Chemistry.

Fibroblast-specific perturbation of transforming growth factor beta signaling provides insight into potential pathogenic mechanisms of scleroderma-associated lung fibrosis: exaggerated response to alveolar epithelial injury in a novel mouse model.

R. D. du Bois, A. Wells, D. Abraham, 2008, Arthritis and rheumatism.

Serial circulating adhesion molecule levels reflect disease severity in systemic sclerosis.

C. Denton, D. Haskard, C. Black, 1995, British journal of rheumatology.

Abnormally differentiating keratinocytes in the epidermis of systemic sclerosis patients show enhanced secretion of CCN2 and S100A9.

D. Abraham, C. Denton, R. Stratton, 2014, The Journal of investigative dermatology.

Interferon-alpha does not improve outcome at one year in patients with diffuse cutaneous scleroderma: results of a randomized, double-blind, placebo-controlled trial.

A. Silman, C. Denton, Helen Wilson, 1999, Arthritis and rheumatism.

Cannabidiol alleviates perfluorooctane sulfonate-induced macrophage extracellular trap mediate inflammation and fibrosis in mice liver.

Hang Yin, Shu Li, D. Luo, 2023, Ecotoxicology and environmental safety.

Co-exposure of avermectin and imidacloprid induces DNA damage, pyroptosis, and immune dysfunction in epithelioma papulosum cyprini cells via ROS-mediated Keap1/Nrf2/TXNIP axis.

Shiwen Xu, Wenying Sun, Dongxu Han, 2023, Fish and Shellfish Immunology.

TBBPA caused apoptosis in grass carp hepatocytes involving destroyed ER-mitochondrial function.

Yujie Yao, N. Yang, Shiwen Xu, 2023, Chemosphere.

Dysregulation of transforming growth factor beta signaling in scleroderma: overexpression of endoglin in cutaneous scleroderma fibroblasts.

Yunliang Chen, D. Pennington, D. Abraham, 2002 .

Tumor Necrosis Factor α Suppresses the Induction of Connective Tissue Growth Factor by Transforming Growth Factor-β in Normal and Scleroderma Fibroblasts*

S. Sa, D. Abraham, A. Leask, 2000, The Journal of Biological Chemistry.

Epigenetic regulation of cyclooxygenase-2 by methylation of c8orf4 in pulmonary fibrosis

G. Laurent, A. Wells, D. Abraham, 2016, Clinical science.

Monocyte chemoattractant protein 3 as a mediator of fibrosis: Overexpression in systemic sclerosis and the type 1 tight-skin mouse.

D. Abraham, C. Denton, V. Rajkumar, 2003, Arthritis and rheumatism.

Polystyrene microplastics with different sizes induce the apoptosis and necroptosis in liver through the PTEN/PI3K/AKT/autophagy axis.

Shiwen Xu, Yue Wang, Xu Shi, 2023, The Science of the total environment.

Inducible lineage-specific deletion of TbetaRII in fibroblasts defines a pivotal regulatory role during adult skin wound healing.

Yunliang Chen, D. Abraham, C. Denton, 2009, The Journal of investigative dermatology.

The control of ccn2 (ctgf) gene expression in normal and scleroderma fibroblasts

S. Sa, D. Abraham, A. Holmes, 2001, Molecular pathology : MP.

Anti-RNA polymerases and other autoantibody specificities in systemic sclerosis.

C. Denton, X. Shi-wen, C. Black, 1998, British journal of rheumatology.

Expression and shedding of intercellular adhesion molecule 1 and lymphocyte function-associated antigen 3 by normal and scleroderma fibroblasts. Effects of interferon-gamma, tumor necrosis factor alpha, and estrogen.

X. Shi-wen, D. Haskard, R. Vancheeswaran, 1994, Arthritis and rheumatism.

Epithelial cells promote fibroblast activation via IL-1alpha in systemic sclerosis.

D. Abraham, C. Denton, A. Leask, 2010, The Journal of investigative dermatology.

Iloprost suppresses connective tissue growth factor production in fibroblasts and in the skin of scleroderma patients.

D. Abraham, A. Holmes, G. Martin, 2001, The Journal of clinical investigation.

Phage transcription activator RinA regulates Staphylococcus aureus virulence by governing sarA expression

Baolin Sun, Ming Jiang, Shiwen Xu, 2022, Genes & Genomics.

Angiogenic effects of stromal cell-derived factor-1 (SDF-1/CXCL12) variants in vitro and the in vivo expressions of CXCL12 variants and CXCR4 in human critical leg ischemia.

D. Baker, D. Abraham, P. Leoni, 2010, Journal of vascular surgery.

miR-130-CYLD Axis Is Involved in the Necroptosis and Inflammation Induced by Selenium Deficiency in Pig Cerebellum

Shengchen Wang, Shiwen Xu, Chunli Sun, 2021, Biological Trace Element Research.

Endothelins: effect on matrix biosynthesis and proliferation in normal and scleroderma fibroblasts.

D. Abraham, C. Denton, A. Holmes, 1998, Journal of cardiovascular pharmacology.

Proteomic analysis of scleroderma lesional skin reveals activated wound healing phenotype of epidermal cell layer.

D. Abraham, C. Denton, D. Aden, 2008, Rheumatology.

Clinical and pathogenic significance of S100A4 overexpression in systemic sclerosis

Feng Zhang, C. Denton, J. Klingelhöfer, 2023, Annals of the Rheumatic Diseases.

Critical Limb Ischaemia in Adult Human Skeletal Muscle Increases Satellite Cell Proliferation but Not Differentiation

D. Baker, D. Abraham, X. Shiwen, 2015 .

Co-exposure to molybdenum and cadmium evokes necroptosis and decreases apoptosis in duck myocardium.

Caiying Zhang, Xueyan Dai, Jiamei Zhu, 2023, The Science of the total environment.