Qingxuan Zeng

发表

Berberine Directly Targets the NEK7 Protein to Block the NEK7-NLRP3 Interaction and Exert Anti-inflammatory Activity.

Wei Wei, Jiandong Jiang, Ying-hong Li, 2020, Journal of medicinal chemistry.

Synthesis and biological evaluation of berberine derivatives as a new class of broad-spectrum antiviral agents against Coxsackievirus B.

Wei Wei, Yu-huan Li, Yanxiang Wang, 2019, Bioorganic chemistry.

Synthesis and Identification of Novel Berberine Derivatives as Potent Inhibitors against TNF-α-Induced NF-κB Activation

Jian-Dong Jiang, Yanxiang Wang, Danqing Song, 2017, Molecules.

Structure-activity relationship and biological evaluation of berberine derivatives as PCSK9 down-regulating agents.

Li Wang, Wei Wei, Yanxiang Wang, 2021, Bioorganic chemistry.

Synthesis and Biological Evaluation of Fangchinoline Derivatives as Anti-Inflammatory Agents through Inactivation of Inflammasome

Ting Liu, Wei Wei, Danqing Song, 2019, Molecules.

Synthesis and Structure–Activity Relationship of Palmatine Derivatives as a Novel Class of Antibacterial Agents against Helicobacter pylori

Xuefu You, Wei Wei, Yanxiang Wang, 2020, Molecules.

Discovery and evolution of 12N-substituted aloperine derivatives as anti-SARS-CoV-2 agents through targeting late entry stage

Wei-Jia Kong, Sheng Tang, Yanxiang Wang, 2021, Bioorganic Chemistry.

Berberine diminishes cancer cell PD-L1 expression and facilitates antitumor immunity via inhibiting the deubiquitination activity of CSN5

M. Yin, N. Zhang, Danqing Song, 2020, Acta pharmaceutica Sinica. B.

Resibufogenin suppresses transforming growth factor‐β‐activated kinase 1‐mediated nuclear factor‐κB activity through protein kinase C‐dependent inhibition of glycogen synthase kinase 3

N. Zhang, M. Yin, Danqing Song, 2018, Cancer science.

Synthesis and Evolution of Berberine Derivatives as a New Class of Antiviral Agents against Enterovirus 71 through the MEK/ERK Pathway and Autophagy

Ting Liu, Yu-huan Li, Yanxiang Wang, 2018, Molecules.

Structure-activity relationship and biological evaluation of 12 N-substituted aloperine derivatives as PD-L1 down-regulatory agents through proteasome pathway.

Xin A. Zhang, Danqing Song, Yueying Dou, 2021, Bioorganic chemistry.

MPB, a novel berberine derivative, enhances lysosomal and bactericidal properties via TGF‐β–activated kinase 1‐dependent activation of the transcription factor EB

M. Yin, N. Zhang, Yanxiang Wang, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Palmatine Derivatives as Potential Antiplatelet Aggregation Agents via Protein Kinase G/Vasodilator-Stimulated Phosphoprotein and Phosphatidylinositol 3-Kinase/Akt Phosphorylation.

Wei-Jia Kong, Wei Wei, Jiandong Jiang, 2022, Journal of medicinal chemistry.

Synthesis and biological evaluation of new berberine derivatives as cancer immunotherapy agents through targeting IDO1.

Jian-Dong Jiang, Yanxiang Wang, Danqing Song, 2018, European journal of medicinal chemistry.

Discovery and identification of EIF2AK2 as a direct key target of berberine for anti-inflammatory effects

Yanxiang Wang, Danqing Song, Hongbin Deng, 2022, Acta pharmaceutica Sinica. B.

Capture and identification of MAP2K7 as a direct proteomic target of berberine to affect JNK pathway

Jian-Dong Jiang, Wei Wei, Sheng Tang, 2022, CCS Chemistry.

Glycogen synthase kinase-3β inhibition promotes lysosome-dependent degradation of c-FLIPL in hepatocellular carcinoma

N. Zhang, Danqing Song, Lu Liu, 2018, Cell Death & Disease.

Synthesis and biological evaluation of 7-substituted cycloberberine derivatives as potent antibacterial agents against MRSA.

Sheng Tang, Yanxiang Wang, Danqing Song, 2019, European journal of medicinal chemistry.

SA-49, a novel aloperine derivative, induces MITF-dependent lysosomal degradation of PD-L1

M. Yin, Xiujun Liu, Danqing Song, 2019, EBioMedicine.

Glycogen synthase kinase-3β inhibition promotes lysosome-dependent degradation of c-FLIPL in hepatocellular carcinoma

N. Zhang, Danqing Song, Lu Liu, 2018, Cell Death and Disease.

A deep learning-driven discovery of berberine derivatives as novel antibacterial against multidrug-resistant Helicobacter pylori

Qingxuan Zeng, Tianyun Fan, Xixi Guo, 2024, Signal transduction and targeted therapy.

Novel berberine derivatives as adjuvants in the battle against Acinetobacter baumannii: A promising strategy for combating multi-drug resistance

Qingxuan Zeng, Tianyun Fan, Xixi Guo, 2024, Chinese Chemical Letters.