Tianyun Fan

发表

Berberine Directly Targets the NEK7 Protein to Block the NEK7-NLRP3 Interaction and Exert Anti-inflammatory Activity.

Wei Wei, Jiandong Jiang, Ying-hong Li, 2020, Journal of medicinal chemistry.

Synthesis and Identification of Novel Berberine Derivatives as Potent Inhibitors against TNF-α-Induced NF-κB Activation

Jian-Dong Jiang, Yanxiang Wang, Danqing Song, 2017, Molecules.

Structure-activity relationship and biological evaluation of berberine derivatives as PCSK9 down-regulating agents.

Li Wang, Wei Wei, Yanxiang Wang, 2021, Bioorganic chemistry.

Discovery and development of palmatine analogues as anti-NASH agents by activating farnesoid X receptor (FXR).

Ying-hong Li, Yanxiang Wang, Danqing Song, 2022, European journal of medicinal chemistry.

Discovery and Development of 8-Substituted Cycloberberine Derivatives as Novel Antibacterial Agents against MRSA.

Jiandong Jiang, Ying-hong Li, Sheng Tang, 2018, ACS medicinal chemistry letters.

Synthesis and Structure–Activity Relationship of Palmatine Derivatives as a Novel Class of Antibacterial Agents against Helicobacter pylori

Xuefu You, Wei Wei, Yanxiang Wang, 2020, Molecules.

Synthesis and biological evaluation of tricyclic matrinic derivatives as a class of novel anti-HCV agents

Jian-Dong Jiang, Zonggen Peng, Xin A. Zhang, 2017, Chemistry Central Journal.

Palmatine Derivatives as Potential Antiplatelet Aggregation Agents via Protein Kinase G/Vasodilator-Stimulated Phosphoprotein and Phosphatidylinositol 3-Kinase/Akt Phosphorylation.

Wei-Jia Kong, Wei Wei, Jiandong Jiang, 2022, Journal of medicinal chemistry.

Synthesis and biological evaluation of new berberine derivatives as cancer immunotherapy agents through targeting IDO1.

Jian-Dong Jiang, Yanxiang Wang, Danqing Song, 2018, European journal of medicinal chemistry.

Discovery and identification of EIF2AK2 as a direct key target of berberine for anti-inflammatory effects

Yanxiang Wang, Danqing Song, Hongbin Deng, 2022, Acta pharmaceutica Sinica. B.

Discovery of 9O-Substituted Palmatine Derivatives as a New Class of Anti-COL1A1 Agents Via Repressing TGF-β1/Smads and JAK1/STAT3 Pathways

N. Zhang, Mao-xu Ge, Danqing Song, 2020, Molecules.

Synthesis and antibacterial evaluation of 13-substituted cycloberberine derivatives as a novel class of anti-MRSA agents.

Sheng Tang, Yanxiang Wang, Danqing Song, 2018, European journal of medicinal chemistry.

Capture and identification of MAP2K7 as a direct proteomic target of berberine to affect JNK pathway

Jian-Dong Jiang, Wei Wei, Sheng Tang, 2022, CCS Chemistry.

Synthesis and biological evaluation of 7-substituted cycloberberine derivatives as potent antibacterial agents against MRSA.

Sheng Tang, Yanxiang Wang, Danqing Song, 2019, European journal of medicinal chemistry.

Evolution and Antibacterial Evaluation of 8-Hydroxy-cycloberberine Derivatives as a Novel Family of Antibacterial Agents Against MRSA

Wei Wei, Sheng Tang, Yanxiang Wang, 2019, Molecules.

Synthesis, Biological Evaluation, and Autophagy Mechanism of 12N-Substituted Sophoridinamines as Novel Anticancer Agents.

N. Zhang, R. Shao, Chong-wen Bi, 2017, ACS medicinal chemistry letters.

Evolution and development of potent monobactam sulfonate candidate IMBZ18g as a dual inhibitor against MDR Gram-negative bacteria producing ESBLs

Xuefu You, Jingpu Zhang, H. Fu, 2023, Acta pharmaceutica Sinica. B.

Evolution and Discovery of Matrine Derivatives as a New Class of Anti-Hepatic Fibrosis Agents Targeting Ewing Sarcoma Breakpoint Region 1 (EWSR1).

Yanxiang Wang, Danqing Song, Tianyun Fan, 2023, Journal of medicinal chemistry.

A deep learning-driven discovery of berberine derivatives as novel antibacterial against multidrug-resistant Helicobacter pylori

Qingxuan Zeng, Tianyun Fan, Xixi Guo, 2024, Signal transduction and targeted therapy.

Novel berberine derivatives as adjuvants in the battle against Acinetobacter baumannii: A promising strategy for combating multi-drug resistance

Qingxuan Zeng, Tianyun Fan, Xixi Guo, 2024, Chinese Chemical Letters.