Joan Subrath

发表

First generation 5-vinyl-3-pyridinecarbonitrile PKCtheta inhibitors.

D. Boschelli, Biqi Wu, Xiaoke Yang, 2009, Bioorganic & medicinal chemistry letters.

Synthesis and characterization of a dual kappa-delta opioid receptor agonist analgesic blocking cocaine reward behavior.

G. Pasternak, A. Váradi, S. Eans, 2015, ACS chemical neuroscience.

Synthesis and evaluation of aryl-naloxamide opiate analgesics targeting truncated exon 11-associated μ opioid receptor (MOR-1) splice variants.

G. Pasternak, Ying-Xian Pan, A. Pasternak, 2012, Journal of medicinal chemistry.

Optimization of 5-phenyl-3-pyridinecarbonitriles as PKCtheta inhibitors.

D. Boschelli, Biqi Wu, Xiaoke Yang, 2009, Bioorganic & medicinal chemistry letters.

Optimization of 5-vinylaryl-3-pyridinecarbonitriles as PKCtheta inhibitors.

D. Boschelli, Biqi Wu, Xiaoke Yang, 2010, Bioorganic & medicinal chemistry letters.

C-5 Substituted heteroaryl 3-pyridinecarbonitriles as PKCtheta inhibitors: Part I.

D. Boschelli, Biqi Wu, Xiaoke Yang, 2009, Bioorganic & medicinal chemistry letters.

Synthesis and Characterization of Azido Aryl Analogs of IBNtxA for Radio-Photoaffinity Labeling Opioid Receptors in Cell Lines and in Mouse Brain

G. Pasternak, Ying-Xian Pan, R. Uprety, 2020, Cellular and Molecular Neurobiology.

Three-Component Coupling Approach for the Synthesis of Diverse Heterocycles Utilizing Reactive Nitrilium Trapping

G. Pasternak, C. Hu, A. Váradi, 2014, Organic letters.

Rubsicolins are naturally occurring G-protein-biased delta opioid receptor peptides

G. Pasternak, M. Lill, Ying-Xian Pan, 2018, bioRxiv.

Synthesis and Characterization of Azido Aryl Analogs of IBNtxA for Radio-Photoaffinity Labeling Opioid Receptors in Cell Lines and in Mouse Brain

G. Pasternak, Ying-Xian Pan, R. Uprety, 2020, Cellular and Molecular Neurobiology.

Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site

Samuel T. Slocum, G. Pasternak, B. Roth, 2021, eLife.

Synthesis of Carfentanil Amide Opioids Using the Ugi Multicomponent Reaction.

G. Pasternak, A. Váradi, A. Borics, 2015, ACS chemical neuroscience.

Discovery and initial optimization of 5,5'-disubstituted aminohydantoins as potent beta-secretase (BACE1) inhibitors.

M. Malamas, K. Fan, A. Robichaud, 2010, Bioorganic & medicinal chemistry letters.

Mitragynine/Corynantheidine Pseudoindoxyls As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit β-Arrestin-2.

G. Pasternak, Ying-Xian Pan, A. Borics, 2016, Journal of medicinal chemistry.