S. Vickers

发表

Pyrrolo(iso)quinoline derivatives as 5-HT(2C) receptor agonists.

G. Kennett, C. Dourish, D. Adams, 2006, Bioorganic & medicinal chemistry letters.

Lisdexamfetamine reduces the compulsive and perseverative behaviour of binge-eating rats in a novel food reward/punished responding conflict model

P. Hutson, D. Heal, S. Vickers, 2016, Journal of psychopharmacology.

GPR39 signaling is stimulated by zinc ions but not by obestatin.

T. Schwartz, B. Holst, Kristoffer L Egerod, 2007, Endocrinology.

Modulation of 5-HT2A receptor-mediated head-twitch behaviour in the rat by 5-HT2C receptor agonists

G. Kennett, R. Porter, N. Easton, 2001, Pharmacology Biochemistry and Behavior.

Modulation of 5-HT(2A) receptor-mediated head-twitch behaviour in the rat by 5-HT(2C) receptor agonists.

G. Kennett, R. Porter, N. Easton, 2001, Pharmacology, biochemistry, and behavior.

Effects of the DPP-4 inhibitor, linagliptin, in diet-induced obese rats: a comparison in naive and exenatide-treated animals.

R. Grempler, B. Hocher, K. Dickinson, 2012, Clinical laboratory.

The cannabinoid CB1 receptor inverse agonist, rimonabant, modifies body weight and adiponectin function in diet-induced obese rats as a consequence of reduced food intake

G. Kennett, Z. Thornton-Jones, P. G. Clifton, 2006, Pharmacology Biochemistry and Behavior.

The utility of animal models to evaluate novel anti‐obesity agents

H. Jackson, S. Cheetham, S. Vickers, 2011, British journal of pharmacology.

Synthesis and biological evaluation of novel hexahydro-pyrido[3',2':4,5]pyrrolo[1,2-a]pyrazines as potent and selective 5-HT(2C) receptor agonists.

P. Mattei, G. Kennett, C. Dourish, 2006, Bioorganic & medicinal chemistry letters.

Identification of 4-methyl-1,2,3,4,10,10a-hexahydropyrazino[1,2-a]indoles as 5-HT2C receptor agonists.

P. Mattei, G. Kennett, C. Dourish, 2005, Bioorganic & medicinal chemistry letters.

A comparison of the effects of the CB1 receptor antagonist SR141716A, pre-feeding and changed palatability on the microstructure of ingestive behaviour

G. Kennett, Z. Thornton-Jones, P. G. Clifton, 2007, Psychopharmacology.

Effect of linagliptin, alone and in combination with voglibose or exendin-4, on glucose control in male ZDF rats.

S. Cheetham, T. Klein, M. Mark, 2014, European journal of pharmacology.

Reduced satiating effect of d-fenfluramine in serotonin 5-HT2C receptor mutant mice

L. Tecott, C. Dourish, P. G. Clifton, 1999, Psychopharmacology.

Comparative effects of continuous infusion of mCPP, Ro 60‐0175 and d‐fenfluramine on food intake, water intake, body weight and locomotor activity in rats

G. Kennett, C. Dourish, G A Kennett, 2000, British journal of pharmacology.

5-HT 2C Receptor Agonists for the Treatment of Obesity. Biological and Chemical Adventures

Caterina Bissantz, C. Bissantz, G. Kennett, 2004 .

5-(pyridinon-1-yl)indazoles and 5-(furopyridinon-5-yl)indazoles as MCH-1 antagonists.

Mark Hadden, S. Cheetham, Y. Khmelnitsky, 2010, Bioorganic & medicinal chemistry letters.

Discovery of Highly Selective Inhibitors of Calmodulin-Dependent Kinases That Restore Insulin Sensitivity in the Diet-Induced Obesity in Vivo Mouse Model

C. Harris, S. Knapp, M. Overduin, 2020, Journal of medicinal chemistry.

5‐HT2C receptor modulation and the treatment of obesity

C. Dourish, C T Dourish, M J Bickerdike, 1999, Diabetes, obesity & metabolism.

Novel targets for the treatment of obesity: a review of progress

Keith Dickinson, David J. Heal, H. Jackson, 2004 .

Evidence that hypophagia induced by d-fenfluramine and d-norfenfluramine in the rat is mediated by 5-HT2C receptors

G. Kennett, C. Dourish, S. Vickers, 2001, Neuropharmacology.

Little and often: ingestive behavior patterns following hippocampal lesions in rats.

P. G. Clifton, E. M. Somerville, S. Vickers, 1998, Behavioral neuroscience.

Characterisation of Pain Responses in the High Fat Diet/Streptozotocin Model of Diabetes and the Analgesic Effects of Antidiabetic Treatments

V. Chapman, S. Cheetham, S. Vickers, 2015, Journal of diabetes research.

Oral administration of the 5-HT2C receptor agonist, mCPP, reduces body weight gain in rats over 28 days as a result of maintained hypophagia

G. Kennett, C. Dourish, N. Easton, 2003, Psychopharmacology.

Antidiabetic effects of the Cimicifuga racemosa extract Ze 450 in vitro and in vivo in ob/ob mice.

J. Drewe, S. Cheetham, S. Vickers, 2014, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Tetrahydrocarboline analogs as MCH-1 antagonists.

Mark Hadden, S. Cheetham, Y. Khmelnitsky, 2010, Bioorganic & medicinal chemistry letters.

Synthesis and SAR of 4-aryl-1-(indazol-5-yl)pyridin-2(1H)ones as MCH-1 antagonists for the treatment of obesity.

Mark Hadden, S. Cheetham, Y. Khmelnitsky, 2010, Bioorganic & medicinal chemistry letters.

Chapter 13 – Preclinical Developments in Antiobesity Drugs

S. Cheetham, S. Vickers, 2007 .

Preferential effects of the cannabinoid CB1 receptor antagonist, SR 141716, on food intake and body weight gain of obese (fa/fa) compared to lean Zucker rats

G. Kennett, C. Dourish, S. Vickers, 2003, Psychopharmacology.

The cannabinoid CB1 receptor antagonist SR141716A reduces appetitive and consummatory responses for food

Z. Thornton-Jones, P. G. Clifton, S. Vickers, 2005, Psychopharmacology.

A sustained release formulation of novel quininib-hyaluronan microneedles inhibits angiogenesis and retinal vascular permeability in vivo.

Alison L. Reynolds, A. Pandit, Oliver Carroll, 2016, Journal of controlled release : official journal of the Controlled Release Society.

The distinct effects of subchronic antipsychotic drug treatment on macronutrient selection, body weight, adiposity, and metabolism in female rats

K. Dickinson, S. Cheetham, K. Marshall, 2007, Psychopharmacology.

Effects of saxagliptin and sitagliptin on glycaemic control and pancreatic β‐cell mass in a streptozotocin‐induced mouse model of type 2 diabetes

M. Kirby, S. Poucher, B. Zinker, 2012, Diabetes, obesity & metabolism.

Effects of lisdexamfetamine in a rat model of binge-eating

F. Murray, P. Hutson, D. Heal, 2015, Journal of psychopharmacology.

Combination of the sodium-glucose cotransporter-2 inhibitor empagliflozin with orlistat or sibutramine further improves the body-weight reduction and glucose homeostasis of obese rats fed a cafeteria diet

R. Grempler, K. Dickinson, S. Cheetham, 2014, Diabetes, metabolic syndrome and obesity : targets and therapy.

Behavioural evidence thatd-fenfluramine-induced anorexia in the rat is not mediated by the 5-HT1A receptor subtype

C. Dourish, P. G. Clifton, S. Vickers, 1996, Psychopharmacology.

Investigation of impulsivity in binge-eating rats in a delay-discounting task and its prevention by the d-amphetamine prodrug, lisdexamfetamine

P. Hutson, D. Heal, S. Vickers, 2017, Journal of psychopharmacology.

Animal models to explore the effects of CNS drugs on food intake and energy expenditure

P. G. Clifton, S. Vickers, 2012, Neuropharmacology.

Prokineticin 2 Is a Hypothalamic Neuropeptide That Potently Inhibits Food Intake

Stephen R. Bloom, Kevin G. Murphy, Saira Hameed, 2009, Diabetes.

Indoline derivatives as 5-HT(2C) receptor agonists.

G. Kennett, C. Dourish, D. Adams, 2004, Bioorganic & medicinal chemistry letters.

Serotonin receptor ligands and the treatment of obesity.

C. Dourish, S. Vickers, 2004, Current opinion in investigational drugs.

Cannabinoids and the regulation of ingestive behaviour.

G. Kennett, S. Vickers, 2005, Current drug targets.

Synthesis and biological evaluation of novel pyrido[3 ',2 ': 4,5]pyrrolo[1,2-a]pyrazines as potent and selective 5-HT2c receptor agonists

P. Mattei, G. Kennett, C. Dourish, 2005 .