L. Krimbou

发表

RVX 208: a small molecule that raises HDL

N. Wong, J. Genest, L. Krimbou, 2010 .

Plasma remnant-like particle lipid and apolipoprotein levels in normolipidemic and hyperlipidemic subjects.

M. Tremblay, K. Nakajima, J. Davignon, 1998, Atherosclerosis.

Association of apolipoprotein E with α2-macroglobulin in human plasma

M. Tremblay, J. Davignon, J. Cohn, 1998 .

Plasma lipoprotein distribution of apoC-III in normolipidemic and hypertriglyceridemic subjects: comparison of the apoC-III to apoE ratio in different lipoprotein fractions.

M. Tremblay, J. Davignon, J. Cohn, 1997, Journal of lipid research.

Comparison of treatment of severe high-density lipoprotein cholesterol deficiency in men with daily atorvastatin (20 mg) versus fenofibrate (200 mg) versus extended-release niacin (2 g).

Z. Awan, J. Genest, I. Ruel, 2008, The American journal of cardiology.

High-density lipoproteins: multifunctional vanguards of the cardiovascular system

M. Marcil, L. Krimbou, Brian O'Connell, 2004, Expert review of cardiovascular therapy.

Familial HDL deficiency characterized by hypercatabolism of mature apoA-I but not proapoA-I.

M. Tremblay, O. Mamer, J. Genest, 1998, Arteriosclerosis, thrombosis, and vascular biology.

Cellular cholesterol transport and efflux in fibroblasts are abnormal in subjects with familial HDL deficiency.

J. Genest, J. Oram, M. Marcil, 1999, Arteriosclerosis, thrombosis, and vascular biology.

Identification of an ABCA1-dependent phospholipid-rich plasma membrane apolipoprotein A-I binding site for nascent HDL formation: implications for current models of HDL biogenesis Published, JLR Papers in Press, July 26, 2007.

I. Iatan, J. Genest, M. Denis, 2007, Journal of Lipid Research.

New insights into the biogenesis of human high-density lipoproteins

J. Genest, M. Marcil, L. Krimbou, 2006, Current opinion in lipidology.

Expression, regulation, and activity of ABCA1 in human cell lines.

M. Bouvier, J. Genest, M. Denis, 2003, Molecular genetics and metabolism.

Structural and functional properties of human plasma high density-sized lipoprotein containing only apoE particles Published, JLR Papers in Press, March 1, 2003. DOI 10.1194/jlr.M200273-JLR200

J. Genest, H. Chiba, M. Marcil, 2003, Journal of Lipid Research.

Characterization of human plasma apolipoprotein E-containing lipoproteins in the high density lipoprotein size range: focus on pre-beta1-LpE, pre-beta2-LpE, and alpha-LpE.

M. Tremblay, J. Davignon, J. Cohn, 1997, Journal of lipid research.

Interaction of lecithin:cholesterol acyltransferase (LCAT).alpha 2-macroglobulin complex with low density lipoprotein receptor-related protein (LRP). Evidence for an alpha 2-macroglobulin/LRP receptor-mediated system participating in LCAT clearance.

J. Genest, J. Davignon, M. Marcil, 2001, The Journal of biological chemistry.

Structural and functional properties of human plasma high density-sized lipoprotein containing only apoE particles

J. Genest, H. Chiba, M. Marcil, 2003 .

Biogenesis and speciation of nascent apoA-I-containing particles in various cell lines Published, JLR Papers in Press, May 16, 2005. DOI 10.1194/jlr.M500038-JLR200

J. Genest, M. Marcil, M. Denis, 2005, Journal of Lipid Research.

Cellular cholesterol homeostasis in vascular endothelial cells.

J. Genest, M. Marcil, M. Denis, 2006, The Canadian journal of cardiology.

Structural modification of plasma HDL by phospholipids promotes efficient ABCA1-mediated cholesterol release Published, JLR Papers in Press, January 16, 2005. DOI 10.1194/jlr.M400477-JLR200

J. Genest, M. Denis, L. Krimbou, 2005, Journal of Lipid Research.

Molecular interactions between apoE and ABCA1: impact on apoE lipidation.

J. Genest, M. Marcil, M. Denis, 2004, Journal of lipid research.

Molecular and Cellular Physiology of Apolipoprotein A-I Lipidation by the ATP-binding Cassette Transporter A1 (ABCA1)*

M. Bouvier, J. Genest, M. Marcil, 2004, Journal of Biological Chemistry.

Compound heterozygosity at the sphingomyelin phosphodiesterase-1 (SMPD1) gene is associated with low HDL cholesterol

J. Genest, M. Marcil, C. Bernard, 2003, Human Genetics.

İnsan HDL'si biyogenezine yeni bakışlar

L. Krimbou, M. Genest, 1990 .

Abstract 679: Oral Administration of Compound RVX-208 Increases Serum Levels of ApoA-I and Improves High-Density Lipoprotein-Mediated Cholesterol Efflux in African Green Monkeys

J. Genest, I. Ruel, L. Krimbou, 2007 .

Carboxyl-terminal disulfide bond of acid sphingomyelinase is critical for its secretion and enzymatic function.

I. Iatan, I. Wada, C. Lazure, 2007, Biochemistry.

In vitro factors affecting the concentration of gamma-LpE (gamma-LpE) in human plasma.

M. Tremblay, J. Davignon, J. Cohn, 1998, Journal of lipid research.

Analysis of lipid transfer activity between model nascent HDL particles and plasma lipoproteins: implications for current concepts of nascent HDL maturation and genesis[S]

I. Iatan, M. Jauhiainen, C. Ehnholm, 2010, Journal of Lipid Research.

Membrane microdomains modulate oligomeric ABCA1 function: impact on apoAI-mediated lipid removal and phosphatidylcholine biosynthesis[S]

I. Iatan, J. Genest, D. Bailey, 2011, Journal of Lipid Research.

Quantitative Analysis of ABCA1-dependent Compartmentalization and Trafficking of Apolipoprotein A-I

I. Iatan, J. Genest, D. Bailey, 2008, Journal of Biological Chemistry.

Association of apolipoprotein E with alpha2-macroglobulin in human plasma.

M. Tremblay, J. Davignon, J. Cohn, 1998, Journal of lipid research.

Increased sphingomyelin content impairs HDL biogenesis and maturation in human Niemann-Pick disease type B Published, JLR Papers in Press, November 30, 2005.

A. Lesimple, O. Mamer, J. Genest, 2006, Journal of Lipid Research.

The HDL proteome in acute coronary syndromes shifts to an inflammatory profile.

Swneke D. Bailey, S. Laboissiere, Z. Awan, 2012, Biochimica et biophysica acta.

cAMP induces ABCA1 phosphorylation activity and promotes cholesterol efflux from fibroblasts Published, JLR Papers in Press, August 16, 2002. DOI 10.1194/jlr.M200235-JLR200

J. Genest, M. Marcil, M. Denis, 2002, Journal of Lipid Research.

Disorders of high‐density lipoprotein biogenesis

I. Iatan, Z. Dastani, J. Genest, 2008 .

A novel nonsense apolipoprotein A-I mutation (apoA-I(E136X)) causes low HDL cholesterol in French Canadians.

P. Pajukanta, R. Hegele, J. Engert, 2006, Atherosclerosis.

Cellular Phospholipid and Cholesterol Efflux in High-Density Lipoprotein Deficiency

J. Genest, M. Marcil, L. Krimbou, 2003, Circulation.

Severe familial HDL deficiency in French-Canadian kindreds. Clinical, biochemical, and molecular characterization.

J. Frohlich, J. Genest, J. Davignon, 1995, Arteriosclerosis, thrombosis, and vascular biology.

Apolipoprotein A-I Activates Cellular cAMP Signaling through the ABCA1 Transporter*

J. Genest, M. Marcil, M. Denis, 2004, Journal of Biological Chemistry.

RVX-208: a small molecule that increases apolipoprotein A-I and high-density lipoprotein cholesterol in vitro and in vivo.

N. Wong, J. Genest, G. Wagner, 2010, Journal of the American College of Cardiology.

Characterization of Oligomeric Human ATP Binding Cassette Transporter A1

M. Bouvier, J. Genest, M. Marcil, 2004, Journal of Biological Chemistry.

Interaction of Lecithin:Cholesterol Acyltransferase (LCAT)·α2-Macroglobulin Complex with Low Density Lipoprotein Receptor-related Protein (LRP)

M. Marcil, L. Krimbou, J. Davignon, 2001, The Journal of Biological Chemistry.

İnsan HDL'si biyogenezine yeni bakışlar

L. Krimbou, M. Genest, 1990 .