D. Milot

发表

2-(4-carbonylphenyl)benzoxazole inhibitors of CETP: scaffold design and advancement in HDLc-raising efficacy.

S. Wright, S. Eveland, S. A. Hyland, 2011, Bioorganic & medicinal chemistry letters.

A high-precision fluorogenic cholesteryl ester transfer protein assay compatible with animal serum and 3456-well assay technology.

Gregory T O'Donnell, M. Ferrer, B. Strulovici, 2007, Analytical biochemistry.

Regulation of lipid metabolism and gene expression by fenofibrate in hamsters.

S. Wright, Melba Hernandez, C. Burton, 2001, Biochimica et biophysica acta.

Different roles of liver X receptor alpha and beta in lipid metabolism: effects of an alpha-selective and a dual agonist in mice deficient in each subtype.

L. Mitnaul, S. Wright, J. Menke, 2006, Biochemical pharmacology.

Protein-disulfide isomerase is a component of an NBD-cholesterol monomerizing protein complex from hamster small intestine.

S. Wright, T. Cai, Liwen Zhang, 2002, Biochimica et biophysica acta.

2-Arylbenzoxazoles as CETP inhibitors: substitution and modification of the alpha-alkoxyamide moiety.

S. Wright, S. Eveland, S. A. Hyland, 2010, Bioorganic & medicinal chemistry letters.

Biphenyl-substituted oxazolidinones as cholesteryl ester transfer protein inhibitors: modifications of the oxazolidinone ring leading to the discovery of anacetrapib.

Amjad Ali, S. Wright, Hong Li, 2011, Journal of medicinal chemistry.

Discovery of substituted biphenyl oxazolidinone inhibitors of cholesteryl ester transfer protein.

Amjad Ali, S. Wright, Zhijian Lu, 2011, ACS medicinal chemistry letters.

High fat fed hamster, a unique animal model for treatment of diabetic dyslipidemia with peroxisome proliferator activated receptor alpha selective agonists.

Y. Chao, M. Wu, J. Ventre, 2001, European journal of pharmacology.

Biochemical characterization of cholesteryl ester transfer protein inhibitors

Nadine H. Elowe, B. Hubbard, M. Garcia-Calvo, 2010, Journal of Lipid Research.

2-Arylbenzoxazoles as CETP inhibitors: raising HDL-C in cynoCETP transgenic mice.

Amjad Ali, S. Wright, Dooseop Kim, 2011, Bioorganic & medicinal chemistry letters.

2-(4-Carbonylphenyl)benzoxazole inhibitors of CETP: attenuation of hERG binding and improved HDLc-raising efficacy.

S. Eveland, S. A. Hyland, C. Sparrow, 2011, Bioorganic & medicinal chemistry letters.

PPARα Agonists Reduce 11β-Hydroxysteroid Dehydrogenase Type 1 in the Liver

Margaret S. Wu, D. Gerhold, R. Thieringer, 2000 .

2-Arylbenzoxazoles as CETP inhibitors: Substitution of the benzoxazole moiety.

Amjad Ali, S. Wright, S. Eveland, 2010, Bioorganic & medicinal chemistry letters.

Different roles of liver X receptor α and β in lipid metabolism: Effects of an α-selective and a dual agonist in mice deficient in each subtype

Qiu Guo, Jayne Chin, L. Mitnaul, 2006 .

SAR studies on the central phenyl ring of substituted biphenyl oxazolidinone-potent CETP inhibitors.

Amjad Ali, S. Wright, Q. Deng, 2012, Bioorganic & medicinal chemistry letters.

Design of a novel class of biphenyl CETP inhibitors.

A. Theberge, Amjad Ali, S. Wright, 2010, Bioorganic & medicinal chemistry letters.

Enhancing Studies of Pharmacodynamic Mechanisms via Measurements of Metabolic Flux: Fundamental Concepts and Guiding Principles for Using Stable Isotope Tracers

M. Erion, D. Johns, D. Kelley, 2017, The Journal of Pharmacology and Experimental Therapeutics.

A Novel Peroxisome Proliferator-Activated Receptor α/γ Dual Agonist Demonstrates Favorable Effects on Lipid Homeostasis

Margaret S. Wu, Y. Chao, J. Berger, 2004 .

PPARalpha agonists reduce 11beta-hydroxysteroid dehydrogenase type 1 in the liver.

D. Gerhold, R. Thieringer, Y. Chao, 2000, Biochemical and biophysical research communications.