Dajun Yang

发表

A two-layered-class approach for the reuse of synchronization code

Ming Zhang, Jian Lu, Mengqiao Xu, 2001, Inf. Softw. Technol..

Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database.

Dajun Yang, Xueliang Fang, Renxiao Wang, 2004, Journal of medicinal chemistry.

Synthesis of a C-terminally biotinylated macrocyclic peptide mimetic exhibiting high Grb2 SH2 domain-binding affinity.

Dajun Yang, Robert J Fisher, Zhen-Dan Shi, 2005, Bioorganic & medicinal chemistry.

Potentiating effect of distant sites in non-phosphorylated cyclic peptide antagonists of the Grb2-SH2 domain.

Dajun Yang, Dajun Yang, P. Roller, 2003, Biochemical and biophysical research communications.

MI-219-Zinc Combination: a new Paradigm in MDM2 Inhibitor Based Therapy

Dajun Yang, Asfar S. Azmi, Fazlul H. Sarkar, 2010, Oncogene.

Macrocyclization in the design of non-phosphorus-containing Grb2 SH2 domain-binding ligands.

Dajun Yang, Robert J Fisher, Zhen-Dan Shi, 2004, Journal of medicinal chemistry.

Potent, orally bioavailable diazabicyclic small-molecule mimetics of second mitochondria-derived activator of caspases.

Dajun Yang, Su Qiu, Han Yi, 2008, Journal of medicinal chemistry.

Macrocyclization in the design of Grb2 SH2 domain-binding ligands exhibiting high potency in whole-cell systems.

Dajun Yang, Manchao Zhang, Dajun Yang, 2003, Journal of medicinal chemistry.

Potent Grb2-SH2 domain antagonists not relying on phosphotyrosine mimics.

Dajun Yang, Megan L Peach, Manchao Zhang, 2003, Bioorganic & medicinal chemistry letters.

A novel macrocyclic tetrapeptide mimetic that exhibits low-picomolar Grb2 SH2 domain-binding affinity.

Dajun Yang, Robert J Fisher, Zhen-Dan Shi, 2003, Biochemical and biophysical research communications.

Design and synthesis of 4-(alpha-hydroxymalonyl)phenylalanine as a new phosphotyrosyl mimetic and its use in growth factor receptor bound 2 src-homology 2 (Grb2 SH2) domain-binding peptides.

Dajun Yang, Robert J Fisher, Sang-Uk Kang, 2005, Journal of medicinal chemistry.

Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database.

Dajun Yang, Xueliang Fang, Renxiao Wang, 2004 .

Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

Dajun Yang, Su Qiu, Guoping Wang, 2008, Proceedings of the National Academy of Sciences.

Potent and orally active small-molecule inhibitors of the MDM2-p53 interaction.

Shanghai Yu, Dajun Yang, Su Qiu, 2009, Journal of medicinal chemistry.

Preclinical studies of Apogossypolone: a new nonpeptidic pan small-molecule inhibitor of Bcl-2, Bcl-XL and Mcl-1 proteins in Follicular Small Cleaved Cell Lymphoma model

Dajun Yang, Shaomeng Wang, R. Mohammad, 2008, Molecular Cancer.

Molecular mechanism of gossypol-induced cell growth inhibition and cell death of HT-29 human colon carcinoma cells.

Dajun Yang, Manchao Zhang, Shaomeng Wang, 2003, Biochemical pharmacology.

A potent and orally active antagonist (SM-406/AT-406) of multiple inhibitor of apoptosis proteins (IAPs) in clinical development for cancer treatment.

Tao Zhang, Dajun Yang, Su Qiu, 2011, Journal of medicinal chemistry.